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Accession:CHEBI:28973 term browser browse the term
Definition:A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
Synonyms:exact_synonym: strychnidin-10-one
 related_synonym: Formula=C21H22N2O2;   InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1;   InChIKey=QMGVPVSNSZLJIA-FVWCLLPLSA-N;   SMILES=[H][C@@]12CC(=O)N3c4ccccc4[C@]45CCN6CC(=CCO1)[C@]([H])(C[C@@]46[H])[C@]2([H])[C@]35[H];   Strychnin
 alt_id: CHEBI:26795;   CHEBI:9293
 xref: BPDB:2066;   Beilstein:52979 "Beilstein";   CAS:57-24-9 "ChemIDplus";   CAS:57-24-9 "KEGG COMPOUND";   CAS:57-24-9 "NIST Chemistry WebBook";   Drug_Central:2484 "DrugCentral";   Gmelin:117894 "Gmelin";   KEGG:C06522;   KNApSAcK:C00001770;   KNApSAcK:C00025213
 xref_mesh: MESH:D013331
 xref: PDBeChem:SY9;   PMID:10471592 "Europe PMC";   PMID:10821054 "Europe PMC";   PMID:11024105 "Europe PMC";   PMID:11157095 "Europe PMC";   PMID:11324564 "Europe PMC";   PMID:11327524 "Europe PMC";   PMID:11453337 "Europe PMC";   PMID:11516560 "Europe PMC";   PMID:11900860 "Europe PMC";   PMID:12611967 "Europe PMC";   PMID:12718443 "Europe PMC";   PMID:12742643 "Europe PMC";   PMID:12757728 "Europe PMC";   PMID:14530208 "Europe PMC";   PMID:14552874 "Europe PMC";   PMID:14575889 "Europe PMC";   PMID:15046720 "Europe PMC";   PMID:15275654 "Europe PMC";   PMID:15302677 "Europe PMC";   PMID:15601738 "Europe PMC";   PMID:15610168 "Europe PMC";   PMID:16075189 "Europe PMC";   PMID:16171972 "Europe PMC";   PMID:16887371 "Europe PMC";   PMID:16950410 "Europe PMC";   PMID:17145135 "Europe PMC";   PMID:17365101 "Europe PMC";   PMID:17449162 "Europe PMC";   PMID:17595105 "Europe PMC";   PMID:17827655 "Europe PMC";   PMID:17900376 "Europe PMC";   PMID:18199816 "Europe PMC";   PMID:19071748 "Europe PMC";   PMID:19194159 "Europe PMC";   PMID:19200346 "Europe PMC";   PMID:19394327 "Europe PMC";   PMID:19445923 "Europe PMC";   PMID:19617896 "Europe PMC";   PMID:19628662 "Europe PMC";   PMID:20534469 "Europe PMC";   PMID:20810461 "Europe PMC";   PMID:20837125 "Europe PMC";   PMID:21042643 "Europe PMC";   PMID:21109870 "Europe PMC";   PMID:21468359 "Europe PMC";   PMID:21506420 "Europe PMC";   PMID:21532268 "Europe PMC";   PMID:21616062 "Europe PMC";   PMID:21618309 "Europe PMC";   PMID:21666516 "Europe PMC";   PMID:21726589 "Europe PMC";   PMID:22168233 "Europe PMC";   PMID:22417832 "Europe PMC";   PMID:23395890 "Europe PMC";   PMID:25702781 "Europe PMC";   PMID:25877308 "Europe PMC";   PMID:25958869 "Europe PMC";   PMID:26028680 "Europe PMC";   PMID:26173662 "Europe PMC";   PMID:26223366 "Europe PMC";   PMID:26330182 "Europe PMC";   PMID:26416729 "Europe PMC";   PMID:26556179 "Europe PMC";   PMID:26625339 "Europe PMC";   PMID:9918589 "Europe PMC";   Reaxys:52979 "Reaxys";   Wikipedia:Strychnine
 cyclic_relationship: is_conjugate_base_of CHEBI:90700

show annotations for term's descendants       view all columns           Sort by:
strychnine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:6480464
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:6480464
G Glra2 glycine receptor, alpha 2 JBrowse link X 30,612,894 30,832,078 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      application 19336
        pesticide 16148
          rodenticide 5823
            strychnine 13
              2-hydroxy-3-methoxystrychnine 0
              alpha-colubrine 0
              beta-colubrine 0
              pseudostrychnine 0
              strychnine N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              cyclic organic group 1833
                                organic heterobicyclic ring 1833
                                  indole skeleton 1833
                                    indole alkaloid 1833
                                      terpenoid indole alkaloid 1464
                                        monoterpenoid indole alkaloid 1455
                                          strychnidine 13
                                            strychnine 13
                                              2-hydroxy-3-methoxystrychnine 0
                                              alpha-colubrine 0
                                              beta-colubrine 0
                                              pseudostrychnine 0
                                              strychnine N-oxide 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.