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ONTOLOGY REPORT - ANNOTATIONS


Term:ampicillin
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Accession:CHEBI:28971 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.
Synonyms:exact_synonym: 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;   (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   (2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid;   ABPC;   AMP;   AP;   D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid;   D-(-)-ampicillin;   Formula=C16H19N3O4S;   InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1;   InChIKey=AVKUERGKIZMTKX-NJBDSQKTSA-N;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O;   aminobenzylpenicillin;   ampicilina;   ampicillin acid;   ampicillin anhydrous;   ampicilline;   ampicillinum
 alt_id: CHEBI:22536;   CHEBI:2683;   CHEBI:40648;   CHEBI:45042
 xref: Beilstein:4300240 "Beilstein";   CAS:69-53-4 "ChemIDplus";   DrugBank:DB00415;   Drug_Central:198 "DrugCentral";   HMDB:HMDB0014559;   KEGG:C06574;   KEGG:D00204;   LINCS:LSM-5761
 xref_mesh: MESH:D000667
 xref: PDB:1H8S;   PDBeChem:AIC;   PDBeChem:PN1;   PMID:10930630 "Europe PMC";   PMID:12562703 "Europe PMC";   PMID:12569987 "Europe PMC";   PMID:12833570 "Europe PMC";   PMID:14139119 "Europe PMC";   PMID:14455820 "Europe PMC";   PMID:15768449 "Europe PMC";   PMID:16033609 "Europe PMC";   PMID:18611716 "Europe PMC";   PMID:19967069 "Europe PMC";   PMID:2083978 "Europe PMC";   PMID:23568176 "Europe PMC";   PMID:23861268 "Europe PMC";   PMID:24474427 "Europe PMC";   PMID:24666465 "Europe PMC";   PMID:25998949 "Europe PMC";   PMID:28543395 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:6176550 "Europe PMC";   PMID:8020088 "Europe PMC";   PMID:9433938 "Europe PMC";   Patent:GB902703;   Patent:US2985648;   Patent:US3157640;   Reaxys:4300240 "Reaxys";   VSDB:1849;   Wikipedia:Ampicillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:50658


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ampicillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Amot angiomotin JBrowse link X 116,751,231 116,810,238 RGD:6480464
G Ankrd1 ankyrin repeat domain 1 JBrowse link 1 254,726,985 254,745,673 RGD:6480464
G Aqp3 aquaporin 3 (Gill blood group) JBrowse link 5 57,423,735 57,429,252 RGD:6480464
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:6480464
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:6480464
G Arrdc3 arrestin domain containing 3 JBrowse link 2 8,732,907 8,745,445 RGD:6480464
G Arrdc4 arrestin domain containing 4 JBrowse link 1 129,766,097 129,780,076 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bpifb2 BPI fold containing family B, member 2 JBrowse link 3 149,358,881 149,377,867 RGD:6480464
G Ca9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:6480464
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:6480464
G Ccpg1 cell cycle progression 1 JBrowse link 8 79,660,634 79,692,044 RGD:6480464
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Chst15 carbohydrate sulfotransferase 15 JBrowse link 1 204,243,396 204,328,960 RGD:6480464
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:6480464
G Clgn calmegin JBrowse link 19 24,545,257 24,578,527 RGD:6480464
G Clic3 chloride intracellular channel 3 JBrowse link 3 2,675,732 2,678,248 RGD:6480464
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:6480464
G Creb3l3 cAMP responsive element binding protein 3-like 3 JBrowse link 7 11,490,852 11,499,287 RGD:6480464
G Csta cystatin A JBrowse link 11 67,555,792 67,566,980 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:6480464
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:6480464
G Dusp7 dual specificity phosphatase 7 JBrowse link 8 115,069,095 115,076,130 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Esm1 endothelial cell-specific molecule 1 JBrowse link 2 45,104,392 45,113,130 RGD:6480464
G Filip1l filamin A interacting protein 1-like JBrowse link 11 45,039,488 45,275,141 RGD:6480464
G Fxyd1 FXYD domain-containing ion transport regulator 1 JBrowse link 1 89,484,197 89,488,279 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hoxd1 homeo box D1 JBrowse link 3 61,685,619 61,687,758 RGD:6480464
G Ifrd1 interferon-related developmental regulator 1 JBrowse link 6 60,132,025 60,151,354 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Jdp2 Jun dimerization protein 2 JBrowse link 6 109,464,910 109,505,591 RGD:6480464
G Jund JunD proto-oncogene, AP-1 transcription factor subunit JBrowse link 16 20,485,028 20,486,707 RGD:6480464
G Lox lysyl oxidase JBrowse link 18 47,500,320 47,577,819 RGD:6480464
G Maz MYC associated zinc finger protein JBrowse link 1 198,456,699 198,460,126 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mtss2 MTSS I-BAR domain containing 2 JBrowse link 19 40,904,779 40,925,660 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Pa2g4 proliferation-associated 2G4 JBrowse link 7 2,979,587 2,987,055 RGD:6480464
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like JBrowse link 3 160,410,733 160,447,073 RGD:6480464
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 19 597,427 601,556 RGD:6480464
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:6480464
G Pgc progastricsin JBrowse link 9 15,266,699 15,274,917 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Pir pirin JBrowse link X 31,852,322 31,968,152 RGD:6480464
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
G Plppr1 phospholipid phosphatase related 1 JBrowse link 5 67,852,817 67,985,310 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G Ptgr1 prostaglandin reductase 1 JBrowse link 5 76,110,746 76,129,361 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptms parathymosin JBrowse link 4 157,435,371 157,439,507 RGD:6480464
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:6480464
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:6480464
G Samd1 sterile alpha motif domain containing 1 JBrowse link 19 25,119,560 25,122,781 RGD:6480464
G Sgk2 serum/glucocorticoid regulated kinase 2 JBrowse link 3 159,361,313 159,385,843 RGD:6480464
G Slc1a2 solute carrier family 1 member 2 JBrowse link 3 92,518,679 92,665,731 RGD:6480464
G Slc22a15 solute carrier family 22, member 15 JBrowse link 2 204,281,638 204,344,026 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Slc2a3 solute carrier family 2 member 3 JBrowse link 4 155,549,991 155,626,018 RGD:6480464
G Slc6a14 solute carrier family 6 member 14 JBrowse link X 120,624,522 120,647,964 RGD:6480464
G Slc6a8 solute carrier family 6 member 8 JBrowse link X 157,129,987 157,139,321 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Slc9a3r2 SLC9A3 regulator 2 JBrowse link 10 14,003,330 14,015,066 RGD:6480464
G Smim14 small integral membrane protein 14 JBrowse link 14 44,413,636 44,460,044 RGD:6480464
G Srxn1 sulfiredoxin 1 JBrowse link 3 147,608,850 147,614,410 RGD:6480464
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tpm4 tropomyosin 4 JBrowse link 16 19,385,810 19,399,851 RGD:6480464
G Trim16 tripartite motif-containing 16 JBrowse link 10 49,231,660 49,254,653 RGD:6480464
G Ttyh3 tweety family member 3 JBrowse link 12 16,084,078 16,112,672 RGD:6480464
G Tubb1 tubulin, beta 1 class VI JBrowse link 3 172,550,252 172,558,089 RGD:6480464
G Tube1 tubulin, epsilon 1 JBrowse link 20 44,220,823 44,238,830 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        aetiopathogenetic role 18776
          allergen 16864
            penicillin 181
              ampicillin 92
                ampicillin trihydrate 0
                ampicilloyl group + 0
                ampicilloyl-butylamine 0
                bacampicillin + 0
                epicillin 0
                lenampicillin 0
                pivampicillin 0
                sultamicillin + 0
                talampicillin + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                lactam 2856
                                                  beta-lactam 710
                                                    beta-lactam antibiotic 698
                                                      penams 181
                                                        penicillanic acids 181
                                                          penicillanic acid 181
                                                            6-aminopenicillanic acid 181
                                                              penicillin 181
                                                                penicillin allergen 178
                                                                  ampicillin 92
                                                                    ampicillin trihydrate 0
                                                                    ampicilloyl group + 0
                                                                    ampicilloyl-butylamine 0
                                                                    bacampicillin + 0
                                                                    epicillin 0
                                                                    lenampicillin 0
                                                                    pivampicillin 0
                                                                    sultamicillin + 0
                                                                    talampicillin + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.