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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:angelicin
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Accession:CHEBI:28928 term browser browse the term
Definition:A furanocoumarin that has formula C11H6O3.
Synonyms:exact_synonym: 2H-furo[2,3-h]chromen-2-one
 related_synonym: Formula=C11H6O3;   InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H;   InChIKey=XDROKJSWHURZGO-UHFFFAOYSA-N;   Isopsoralen;   SMILES=O=c1ccc2ccc3occc3c2o1
 alt_id: CHEBI:24918;   CHEBI:2717
 xref: Beilstein:153970;   CAS:523-50-2;   KEGG:C09060;   KNApSAcK:C00002450
 xref_mesh: MESH:C011659


show annotations for term's descendants           Sort by:
angelicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP angelicin results in decreased expression of ABCB11 mRNA; angelicin results in decreased expression of ABCB11 protein CTD PMID:30597224 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP angelicin results in decreased expression of ABCC2 mRNA; angelicin results in decreased expression of ABCC2 protein CTD PMID:30597224 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP angelicin results in increased expression of ABCC3 mRNA; angelicin results in increased expression of ABCC3 protein CTD PMID:30597224 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects expression ISO angelicin affects the expression of ABCC4 mRNA CTD PMID:22173200 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Ahr aryl hydrocarbon receptor increases activity EXP angelicin results in increased activity of AHR protein CTD PMID:15670584 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
increases phosphorylation		 ISO angelicin results in increased expression of AKT1 mRNA
angelicin results in increased phosphorylation of AKT1 protein		 CTD PMID:37069639 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO
EXP		 angelicin results in increased expression of CYP1A1 protein
angelicin results in increased expression of and results in decreased activity of CYP1A1 protein
angelicin results in increased expression of CYP1A1 mRNA		 CTD PMID:15670584 PMID:18692084 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO angelicin results in increased expression of CYP1A2 protein CTD PMID:18692084 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO angelicin results in decreased expression of CYP2E1 protein CTD PMID:22173200 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP angelicin results in decreased expression of CYP7A1 mRNA; angelicin results in decreased expression of CYP7A1 protein CTD PMID:30597224 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP angelicin results in increased expression of GPT protein CTD PMID:30597224 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression
increases phosphorylation		 ISO angelicin results in increased expression of MTOR mRNA
angelicin results in increased phosphorylation of MTOR protein		 CTD PMID:37069639 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression EXP angelicin results in increased expression of NR1H4 mRNA; angelicin results in increased expression of NR1H4 protein CTD PMID:30597224 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO angelicin results in increased expression of PIK3R1 mRNA CTD PMID:37069639 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression
increases expression		 ISO angelicin results in decreased expression of SLC22A1 mRNA
angelicin results in increased expression of SLC22A1 protein		 CTD PMID:22173200 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases expression ISO angelicin results in increased expression of SLC22A2 mRNA; angelicin results in increased expression of SLC22A2 protein CTD PMID:22173200 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a4 solute carrier family 22 member 4 decreases expression ISO angelicin results in decreased expression of SLC22A4 mRNA CTD PMID:22173200 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression ISO angelicin results in increased expression of SLC22A5 protein CTD PMID:22173200 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression ISO angelicin results in increased expression of SLC22A6 protein CTD PMID:22173200 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases expression
decreases expression		 ISO angelicin results in increased expression of SLC22A8 protein
angelicin results in decreased expression of SLC22A8 mRNA		 CTD PMID:22173200 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a9 solute carrier family 2 member 9 increases expression ISO angelicin results in increased expression of SLC2A9 mRNA CTD PMID:22173200 NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP angelicin results in decreased expression of SULT2A1 mRNA; angelicin results in decreased expression of SULT2A1 protein CTD PMID:30597224 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          oxygen atom 19520
            oxygen molecular entity 19490
              organooxygen compound 19137
                oxacycle 17819
                  furochromene 127
                    furanocoumarin 127
                      angelicin 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    organic heterotricyclic compound 15641
                                      furochromene 127
                                        furanocoumarin 127
                                          angelicin 22
paths to the root