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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:estrone 3-O-(beta-D-glucuronide)
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Accession:CHEBI:28919 term browser browse the term
Definition:The 3-beta-D-glucuronide of estrone.
Synonyms:exact_synonym: 17-oxoestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid
 related_synonym: Estrone 3-glucuronide;   Estrone beta-D-glucuronide;   Estrone glucuronide;   Formula=C24H30O8;   InChI=1S/C24H30O8/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30)/t14-,15-,16+,18+,19+,20-,21+,23-,24+/m1/s1;   InChIKey=FJAZVHYPASAQKM-JBAURARKSA-N;   SMILES=C1[C@]2([C@]3([C@@](C4=C(C=C(O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O)C=C4)CC3)(CC[C@@]2(C(=O)C1)C)[H])[H])[H];   estrone 3-glucosiduronic acid
 alt_id: CHEBI:23973;   CHEBI:42342;   CHEBI:4872
 xref: CAS:2479-90-5;   KEGG:C11133;   LIPID_MAPS_instance:LMST05010011
 xref_mesh: MESH:C015856
 xref: PMID:9261086
 cyclic_relationship: is_conjugate_acid_of CHEBI:136634

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estrone 3-O-(beta-D-glucuronide) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho increases hydrolysis
multiple interactions
ISO KL protein results in increased hydrolysis of estrone-3-glucuronide
estrone-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]
CTD PMID:14701853 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pharmaceutical 19329
          drug 19329
            antineoplastic agent 17317
              estrone 127
                estrone 3-O-(beta-D-glucuronide) 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      carbohydrate derivative 11947
                                        glycosyl compound 10977
                                          glycoside 9260
                                            glycosiduronic acid 155
                                              glucosiduronic acid 155
                                                beta-D-glucosiduronic acid 47
                                                  estrone 3-O-(beta-D-glucuronide) 1
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