Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:estrone 3-O-(beta-D-glucuronide)
go back to main search page
Accession:CHEBI:28919 term browser browse the term
Definition:The 3-beta-D-glucuronide of estrone.
Synonyms:exact_synonym: 17-oxoestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid
 related_synonym: Estrone 3-glucuronide;   Estrone beta-D-glucuronide;   Estrone glucuronide;   Formula=C24H30O8;   InChI=1S/C24H30O8/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30)/t14-,15-,16+,18+,19+,20-,21+,23-,24+/m1/s1;   InChIKey=FJAZVHYPASAQKM-JBAURARKSA-N;   SMILES=C1[C@]2([C@]3([C@@](C4=C(C=C(O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O)C=C4)CC3)(CC[C@@]2(C(=O)C1)C)[H])[H])[H];   estrone 3-glucosiduronic acid
 alt_id: CHEBI:23973;   CHEBI:42342;   CHEBI:4872
 xref: CAS:2479-90-5;   KEGG:C11133;   LIPID_MAPS_instance:LMST05010011
 xref_mesh: MESH:C015856
 xref: PMID:9261086
 cyclic_relationship: is_conjugate_acid_of CHEBI:136634


show annotations for term's descendants           Sort by:
 
estrone 3-O-(beta-D-glucuronide) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho increases hydrolysis
multiple interactions
ISO KL protein results in increased hydrolysis of estrone-3-glucuronide
estrone-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]
CTD PMID:14701853 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pharmaceutical 19272
          drug 19272
            antineoplastic agent 16982
              estrone 125
                estrone 3-O-(beta-D-glucuronide) 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            heteroorganic entity 19147
                              organochalcogen compound 18855
                                organooxygen compound 18777
                                  carbohydrates and carbohydrate derivatives 12178
                                    carbohydrate 12178
                                      carbohydrate derivative 11802
                                        glycosyl compound 10846
                                          glycoside 9202
                                            glycosiduronic acid 139
                                              glucosiduronic acid 139
                                                beta-D-glucosiduronic acid 45
                                                  estrone 3-O-(beta-D-glucuronide) 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.