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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fosfomycin
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Accession:CHEBI:28915 term browser browse the term
Definition:A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus.
Synonyms:related_synonym: (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid;   (1R,2S)-epoxypropylphosphonic acid;   (2R-cis)-(3-Methyloxiranyl)phosphonic acid;   1R-cis-(1,2-epoxypropyl)phosphonic acid;   FCM;   Formula=C3H7O4P;   InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1;   InChIKey=YMDXZJFXQJVXBF-STHAYSLISA-N;   L-cis-1,2-epoxypropylphosphonic acid;   Phosphomycin;   Phosphonomycin;   SMILES=C[C@@H]1O[C@@H]1P(O)(O)=O;   [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid;   cis-(1R,2S)-epoxypropylphosphonic acid;   fosfomicina;   fosfomycine;   fosfomycinum;   phosphonemycin
 alt_id: CHEBI:24100;   CHEBI:42503;   CHEBI:8159
 xref: CAS:23155-02-4;   DrugBank:DB00828;   Drug_Central:1243;   KEGG:C06454;   KEGG:D04253;   KNApSAcK:C00000789
 xref_mesh: MESH:D005578
 xref: MetaCyc:CPD0-1113;   PDBeChem:FCN;   PMID:105327;   PMID:17124631;   PMID:19308743;   PMID:2660079;   PMID:288976;   PMID:3464490;   PMID:3900889;   PMID:488578;   PMID:614140;   PMID:6348659;   PMID:6796449;   PMID:7030849;   PMID:7224844;   PMID:740308;   PMID:9309262;   Reaxys:1680831
 cyclic_relationship: is_conjugate_acid_of CHEBI:62247



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fosfomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp5 aquaporin 5 decreases expression EXP Fosfomycin results in decreased expression of AQP5 protein CTD PMID:30031112 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Crp C-reactive protein decreases expression ISO Fosfomycin results in decreased expression of CRP protein CTD PMID:12680319 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        antimicrobial agent 17482
          fosfomycin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic molecule 19562
                              organic cyclic compound 19356
                                organic heterocyclic compound 18596
                                  organic heteromonocyclic compound 17120
                                    saturated organic heteromonocyclic parent 9775
                                      oxirane 9755
                                        epoxide 9754
                                          fosfomycin 2
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