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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:busulfan
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Accession:CHEBI:28901 term browser browse the term
Definition:A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
Synonyms:exact_synonym: butane-1,4-diyl dimethanesulfonate
 related_synonym: 1,4-Bis(methanesulfonoxy)butane;   1,4-Butanediol dimethanesulfonate;   1,4-Dimesyloxybutane;   1,4-Dimethanesulfonoxybutane;   Bisulfex;   Formula=C6H14O6S2;   InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3;   InChIKey=COVZYZSDYWQREU-UHFFFAOYSA-N;   Leucosulfan;   Mablin;   Mielucin;   Misulban;   Mitostan;   Myeloleukon;   Myleran;   SMILES=CS(=O)(=O)OCCCCOS(C)(=O)=O;   Tetramethylene bis(methanesulfonate);   busulfano;   busulfanum
 alt_id: CHEBI:18936;   CHEBI:3225
 xref: Beilstein:1791786;   CAS:55-98-1;   DrugBank:DB01008;   Drug_Central:438;   KEGG:C06862;   KEGG:D00248;   LINCS:LSM-5388
 xref_mesh: MESH:D002066
 xref: PMID:10523796;   PMID:19361744;   PMID:19611402;   Patent:US2917432;   Reaxys:1791786;   Wikipedia:Busulfan


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  CHEBI ontology 0
    role 0
      biological role 0
        aetiopathogenetic role 0
          carcinogenic agent 0
            busulfan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      chalcogen 0
                        oxygen atom 0
                          oxygen molecular entity 0
                            hydroxides 0
                              oxoacid 0
                                chalcogen oxoacid 0
                                  sulfur oxoacid 0
                                    sulfonic acid 0
                                      sulfo group 0
                                        organosulfonic acid 0
                                          alkanesulfonic acid 0
                                            methanesulfonic acid 0
                                              methanesulfonates 0
                                                methanesulfonate ester 0
                                                  busulfan 0
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