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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:melphalan
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Accession:CHEBI:28876 term browser browse the term
Definition:A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Synonyms:related_synonym: 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine;   4-(Bis(2-chloroethyl)amino)-L-phenylalanine;   Formula=C13H18Cl2N2O2;   InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1;   InChIKey=SGDBTWWWUNNDEQ-LBPRGKRZSA-N;   L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine;   L-PAM;   L-Phenylalanine mustard;   L-Sarcolysine;   Phenylalanine mustard;   Phenylalanine nitrogen mustard;   SMILES=N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O;   melfalano;   melphalanum;   p-Bis(beta-chloroethyl)aminophenylalanine;   p-Di-(2-chloroethyl)amino-L-phenylalanine;   p-L-Sarcolysin;   p-N,N-bis(2-chloroethyl)amino-L-phenylalanine;   p-N-Bis(2-chloroethyl)amino-L-phenylalanine
 alt_id: CHEBI:25815;   CHEBI:6742
 xref: CAS:148-82-3;   DrugBank:DB01042;   Drug_Central:1678;   KEGG:D00369
 xref_mesh: MESH:D008558
 xref: PMID:10820424;   PMID:10937717;   PMID:11680815;   PMID:11914777;   PMID:18481314;   PMID:445303;   PMID:7494795;   PMID:7605343;   PMID:8552138;   PMID:8951232;   PMID:9218926;   PMID:9250538;   Patent:US108552;   Patent:US275057;   Patent:US3032584;   Patent:US3032585;   Reaxys:2816456;   Wikipedia:Melphalan

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melphalan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export ISO ABCC1 protein affects the export of Melphalan analog CTD PMID:11115505 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO Melphalan results in decreased expression of ABHD17C mRNA CTD PMID:22363485 NCBI chr 1:146,248,505...146,289,465
Ensembl chr 1:146,248,503...146,289,465 		JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit decreases expression ISO Melphalan results in decreased expression of ABRAXAS1 mRNA CTD PMID:22363485 NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003 		JBrowse link
G Abt1 activator of basal transcription 1 increases expression ISO Melphalan results in increased expression of ABT1 mRNA CTD PMID:22363485 NCBI chr17:43,946,118...43,948,224
Ensembl chr17:43,946,130...43,948,223 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Melphalan results in increased expression of ACKR3 mRNA CTD PMID:22363485 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445 		JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Melphalan results in decreased expression of ACVR1C mRNA CTD PMID:22363485 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO Melphalan results in decreased expression of AHRR mRNA CTD PMID:22363485 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329 		JBrowse link
G Alad aminolevulinate dehydratase decreases activity ISO Melphalan results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346 		JBrowse link
G Ammecr1l AMMECR1 like increases expression ISO Melphalan results in increased expression of AMMECR1L mRNA CTD PMID:22363485 NCBI chr18:24,539,530...24,563,576
Ensembl chr18:24,540,659...24,563,576 		JBrowse link
G Ankar ankyrin and armadillo repeat containing decreases expression ISO Melphalan results in decreased expression of ANKAR mRNA CTD PMID:22363485 NCBI chr 9:53,011,561...53,086,178
Ensembl chr 9:53,013,413...53,084,010 		JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Melphalan results in increased expression of ANKRD10 mRNA CTD PMID:22363485 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194 		JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression ISO Melphalan results in decreased expression of ANKRD28 mRNA CTD PMID:22363485 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Melphalan results in decreased expression of ANKRD34A mRNA CTD PMID:22363485 NCBI chr 2:198,720,277...198,725,155
Ensembl chr 2:198,721,724...198,725,154 		JBrowse link
G Ar androgen receptor decreases expression ISO Melphalan results in decreased expression of AR mRNA CTD PMID:22363485 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Arhgap12 Rho GTPase activating protein 12 decreases expression ISO Melphalan results in decreased expression of ARHGAP12 mRNA CTD PMID:22363485 NCBI chr17:54,280,815...54,394,716
Ensembl chr17:54,280,851...54,394,634 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Melphalan results in decreased expression of ARHGAP18 mRNA CTD PMID:22363485 NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301 		JBrowse link
G Arhgap20 Rho GTPase activating protein 20 decreases expression ISO Melphalan results in decreased expression of ARHGAP20 mRNA CTD PMID:22363485 NCBI chr 8:56,179,581...56,264,343
Ensembl chr 8:56,179,637...56,264,263 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO Melphalan results in decreased expression of ARHGAP24 mRNA CTD PMID:22363485 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO Melphalan results in decreased expression of ARHGAP42 mRNA CTD PMID:22363485 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Melphalan results in increased expression of ARID5A mRNA CTD PMID:22363485 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855 		JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression ISO Melphalan results in increased expression of ATG16L1 mRNA CTD PMID:22363485 NCBI chr 9:94,879,876...94,915,231
Ensembl chr 9:94,879,745...94,915,228 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Melphalan results in decreased expression of ATP2B1 mRNA CTD PMID:22363485 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Aurka aurora kinase A increases expression ISO Melphalan results in increased expression of AURKA protein CTD PMID:22025197 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Melphalan results in decreased expression of AURKB protein CTD PMID:22025197 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991 		JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 increases expression ISO Melphalan results in increased expression of B3GNT2 mRNA CTD PMID:22363485 NCBI chr14:107,592,336...107,617,189
Ensembl chr14:107,592,336...107,617,161 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Melphalan results in increased expression of B3GNT5 mRNA CTD PMID:22363485 NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Melphalan results in increased expression of BAK1 protein CTD PMID:22285227 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Melphalan results in increased expression of and results in decreased localization of BAX protein CTD PMID:22285227 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein CTD PMID:4672170 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Melphalan results in decreased expression of BCL2 protein CTD PMID:22285227 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Melphalan results in increased expression of BCL2A1 mRNA CTD PMID:22363485 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483 		JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO Melphalan results in decreased expression of BICC1 mRNA CTD PMID:22363485 NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408 		JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 increases expression ISO Melphalan results in increased expression of BICDL2 mRNA CTD PMID:22363485 NCBI chr10:12,980,696...12,989,133
Ensembl chr10:12,980,674...12,992,780 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects response to substance
decreases expression
multiple interactions		 ISO BIRC5 protein affects the susceptibility to Melphalan
Melphalan results in decreased expression of BIRC5 protein
Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]; Paclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]		 CTD PMID:16373717 PMID:22025197 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO Melphalan results in decreased expression of BNC2 mRNA CTD PMID:22363485 NCBI chr 5:102,407,508...102,807,389
Ensembl chr 5:102,415,847...102,786,331 		JBrowse link
G Btbd8 BTB domain containing 8 decreases expression ISO Melphalan results in decreased expression of BTBD8 mRNA CTD PMID:22363485 NCBI chr14:3,282,422...3,351,740
Ensembl chr14:3,284,089...3,300,200 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Melphalan results in increased expression of BTG2 mRNA CTD PMID:22363485 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982 		JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression ISO Melphalan results in decreased expression of CABLES1 mRNA CTD PMID:22363485 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721 		JBrowse link
G Casp3 caspase 3 increases activity ISO Melphalan results in increased activity of CASP3 protein CTD PMID:16951922 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Melphalan results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:22285227 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase decreases activity ISO Melphalan results in decreased activity of CAT protein CTD PMID:19162187 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Melphalan results in decreased expression of CC2D2A mRNA CTD PMID:22363485 NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419 		JBrowse link
G Ccdc110 coiled-coil domain containing 110 decreases expression ISO Melphalan results in decreased expression of CCDC110 mRNA CTD PMID:22363485 NCBI chr16:49,509,885...49,522,094
Ensembl chr16:49,509,876...49,522,341
Ensembl chr16:49,509,876...49,522,341 		JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO Melphalan results in decreased expression of CCDC171 mRNA CTD PMID:22363485 NCBI chr 5:101,639,355...102,017,300 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Melphalan results in increased expression of CCL20 mRNA CTD PMID:22363485 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccnj cyclin J increases expression ISO Melphalan results in increased expression of CCNJ mRNA CTD PMID:22363485 NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254
Ensembl chr 1:260,093,641...260,111,254 		JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein CTD PMID:10618687 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Cd59 CD59 molecule decreases lipidation EXP Melphalan results in decreased lipidation of CD59 protein CTD PMID:27931811 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621 		JBrowse link
G Cda cytidine deaminase decreases response to substance ISO CDA protein results in decreased susceptibility to Melphalan CTD PMID:10830723 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541 		JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Melphalan results in decreased expression of CDC14B mRNA CTD PMID:22363485 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Melphalan results in decreased expression of CDC42EP3 mRNA CTD PMID:22363485 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972 		JBrowse link
G Cfap206 cilia and flagella associated protein 206 decreases expression ISO Melphalan results in decreased expression of CFAP206 mRNA CTD PMID:22363485 NCBI chr 5:50,148,685...50,193,580
Ensembl chr 5:50,148,658...50,193,571 		JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK1 protein CTD PMID:26208482 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK2 protein CTD PMID:26208482 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex affects phosphorylation ISO Melphalan affects the phosphorylation of CHUK protein CTD PMID:19934314 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Melphalan results in decreased expression of CIITA mRNA CTD PMID:22363485 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 increases expression ISO Melphalan results in increased expression of CITED4 mRNA CTD PMID:22363485 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622 		JBrowse link
G Cnksr3 Cnksr family member 3 decreases expression ISO Melphalan results in decreased expression of CNKSR3 mRNA CTD PMID:22363485 NCBI chr 1:43,789,797...43,884,267
Ensembl chr 1:43,789,791...43,884,267 		JBrowse link
G Cpne8 copine 8 decreases expression ISO Melphalan results in decreased expression of CPNE8 mRNA CTD PMID:22363485 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO Melphalan results in decreased expression of CREB5 mRNA CTD PMID:22363485 NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351 		JBrowse link
G Cul3 cullin 3 increases expression ISO Melphalan results in increased expression of CUL3 mRNA CTD PMID:22363485 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Melphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP		 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP		 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Melphalan results in increased expression of CYP27B1 mRNA CTD PMID:22363485 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005 		JBrowse link
G Cyria CYFIP related Rac1 interactor A decreases expression ISO Melphalan results in decreased expression of CYRIA mRNA CTD PMID:22363485 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064 		JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO Melphalan results in increased expression of DBF4 mRNA CTD PMID:22363485 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177 		JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323 		JBrowse link
G Dennd4c DENN domain containing 4C decreases expression ISO Melphalan results in decreased expression of DENND4C mRNA CTD PMID:22363485 NCBI chr 5:105,100,081...105,195,634
Ensembl chr 5:105,114,433...105,193,988 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 decreases expression ISO Melphalan results in decreased expression of DLG3 mRNA CTD PMID:22363485 NCBI chr  X:70,596,246...70,648,529
Ensembl chr  X:70,596,576...70,648,532 		JBrowse link
G Dst dystonin decreases expression ISO Melphalan results in decreased expression of DST mRNA CTD PMID:22363485 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Melphalan results in increased expression of DUSP2 mRNA CTD PMID:22363485 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099 		JBrowse link
G Eaf1 ELL associated factor 1 increases expression ISO Melphalan results in increased expression of EAF1 mRNA CTD PMID:22363485 NCBI chr16:7,588,217...7,602,966
Ensembl chr16:7,588,217...7,602,966 		JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Melphalan results in decreased expression of EBF1 mRNA CTD PMID:22363485 NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Melphalan results in increased expression of EDN1 protein CTD PMID:18548196 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 decreases expression ISO Melphalan results in decreased expression of EEPD1 mRNA CTD PMID:22363485 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325 		JBrowse link
G Efna2 ephrin A2 increases expression ISO Melphalan results in increased expression of EFNA2 mRNA CTD PMID:22363485 NCBI chr 7:12,382,636...12,393,266
Ensembl chr 7:12,382,636...12,393,266 		JBrowse link
G Efna5 ephrin A5 decreases expression ISO Melphalan results in decreased expression of EFNA5 mRNA CTD PMID:22363485 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486 		JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Melphalan results in decreased expression of EMX2 mRNA CTD PMID:22363485 NCBI chr 1:280,633,938...280,640,946
Ensembl chr 1:280,633,938...280,640,946 		JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO Melphalan results in decreased expression of ENOX1 mRNA CTD PMID:22363485 NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511 		JBrowse link
G Epha5 EPH receptor A5 decreases expression ISO Melphalan results in decreased expression of EPHA5 mRNA CTD PMID:22363485 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227 		JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO Melphalan results in decreased expression of EXOC6 mRNA CTD PMID:22363485 NCBI chr 1:256,211,879...256,369,318
Ensembl chr 1:256,226,179...256,368,813 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Melphalan results in increased expression of FABP5 mRNA CTD PMID:22363485 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378 		JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression ISO Melphalan results in decreased expression of FAM110B mRNA CTD PMID:22363485 NCBI chr 5:18,762,488...18,903,818
Ensembl chr 5:18,901,039...18,902,672 		JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 decreases expression ISO Melphalan results in decreased expression of FAM90A1 mRNA CTD PMID:22363485 NCBI chr16:75,001,033...75,016,173 JBrowse link
G Fancc FA complementation group C increases response to substance ISO FANCC protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615 		JBrowse link
G Fancg FA complementation group G increases response to substance ISO FANCG protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819 		JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO Melphalan results in decreased expression of FAT4 mRNA CTD PMID:22363485 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
Ensembl chr 2:125,752,130...125,879,387 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 decreases expression ISO Melphalan results in decreased expression of FGD4 mRNA CTD PMID:22363485 NCBI chr11:88,699,222...88,796,677
Ensembl chr11:88,699,222...88,796,677 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 decreases expression ISO Melphalan results in decreased expression of FGD6 mRNA CTD PMID:22363485 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Melphalan results in decreased expression of FGF5 mRNA CTD PMID:22363485 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584 		JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Melphalan results in decreased expression of FIGN mRNA CTD PMID:22363485 NCBI chr 3:49,992,250...50,120,601
Ensembl chr 3:49,992,397...50,120,392 		JBrowse link
G Fmn2 formin 2 decreases expression ISO Melphalan results in decreased expression of FMN2 mRNA CTD PMID:22363485 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Melphalan results in increased expression of FOSB mRNA CTD PMID:22363485 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO Melphalan results in decreased expression of FOXP2 mRNA CTD PMID:22363485 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023 		JBrowse link
G Frmd4a FERM domain containing 4A decreases expression ISO Melphalan results in decreased expression of FRMD4A mRNA CTD PMID:22363485 NCBI chr17:77,642,302...77,918,210 JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO Melphalan results in decreased expression of FRMD4B mRNA CTD PMID:22363485 NCBI chr 4:129,658,137...129,984,735
Ensembl chr 4:129,658,840...129,846,642 		JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Melphalan results in decreased expression of FRY mRNA CTD PMID:22363485 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874 		JBrowse link
G Fut10 fucosyltransferase 10 decreases expression ISO Melphalan results in decreased expression of FUT10 mRNA CTD PMID:22363485 NCBI chr16:64,623,246...64,716,248
Ensembl chr16:64,631,264...64,716,224 		JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression ISO Melphalan results in decreased expression of GAB1 mRNA CTD PMID:22363485 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 decreases expression ISO Melphalan results in decreased expression of GAREM1 mRNA CTD PMID:22363485 NCBI chr18:14,982,604...15,007,245
Ensembl chr18:12,224,514...12,284,188 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO Melphalan results in decreased expression of GAS1 mRNA CTD PMID:22363485 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940 		JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 decreases expression ISO Melphalan results in decreased expression of GCNT1 mRNA CTD PMID:22363485 NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035 		JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO Melphalan results in decreased expression of GLI3 mRNA CTD PMID:22363485 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO Melphalan results in increased expression of GRIN2C mRNA CTD PMID:22363485 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 decreases expression ISO Melphalan results in decreased expression of GRK5 mRNA CTD PMID:22363485 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Melphalan CTD PMID:8860835 PMID:10215608 PMID:10830723 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases response to substance EXP GSTA5 protein results in decreased susceptibility to Melphalan CTD PMID:12076520 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases response to substance ISO GSTM1 protein results in decreased susceptibility to Melphalan CTD PMID:20067466 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]; Melphalan inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:12791655 PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO Melphalan results in decreased expression of HECW2 mRNA CTD PMID:22363485 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO Melphalan results in decreased expression of HGF mRNA CTD PMID:22363485 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Melphalan results in decreased expression of HMGA2 mRNA CTD PMID:22363485 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408 		JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Melphalan results in increased expression of HOXD1 mRNA CTD PMID:22363485 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Melphalan results in increased expression of ICAM1 protein CTD PMID:16025434 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO Melphalan results in increased expression of IER3 mRNA CTD PMID:22363485 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO Melphalan results in decreased expression of IKBKE mRNA CTD PMID:22363485 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Melphalan results in decreased expression of IKZF2 mRNA CTD PMID:22363485 NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806 		JBrowse link
G Il12a interleukin 12A increases expression ISO Melphalan results in increased expression of IL12A mRNA CTD PMID:22363485 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318 		JBrowse link
G Il16 interleukin 16 decreases expression ISO Melphalan results in decreased expression of IL16 mRNA CTD PMID:22363485 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO Melphalan results in increased expression of and results in increased secretion of IL1B protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]
Melphalan results in increased expression of IL1B mRNA		 CTD PMID:21129433 PMID:22363485 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions		 ISO Melphalan results in increased expression of IL23A protein
TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]		 CTD PMID:21129433 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Melphalan results in increased expression of and results in increased secretion of IL6 protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein] CTD PMID:21129433 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il7 interleukin 7 decreases expression ISO Melphalan results in decreased expression of IL7 mRNA CTD PMID:22363485 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977 		JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Melphalan results in decreased expression of IRF2 mRNA CTD PMID:22363485 NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932 		JBrowse link
G Jade2 jade family PHD finger 2 decreases expression ISO Melphalan results in decreased expression of JADE2 mRNA CTD PMID:22363485 NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625 		JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 decreases expression ISO Melphalan results in decreased expression of JAKMIP3 mRNA CTD PMID:22363485 NCBI chr 1:211,292,604...211,421,023
Ensembl chr 1:211,351,350...211,421,022 		JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO Melphalan results in decreased expression of KALRN mRNA CTD PMID:22363485 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633 		JBrowse link
G Kbtbd3 kelch repeat and BTB domain containing 3 decreases expression ISO Melphalan results in decreased expression of KBTBD3 mRNA CTD PMID:22363485 NCBI chr 8:1,450,345...1,477,250
Ensembl chr 8:1,459,526...1,476,837 		JBrowse link
G Kitlg KIT ligand decreases expression ISO Melphalan results in decreased expression of KITLG mRNA CTD PMID:22363485 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054 		JBrowse link
G Klf12 Kruppel-like factor 12 decreases expression ISO Melphalan results in decreased expression of KLF12 mRNA CTD PMID:22363485 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525 		JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Melphalan results in increased expression of KLHL42 mRNA CTD PMID:22363485 NCBI chr 4:181,481,147...181,502,916
Ensembl chr 4:181,481,147...181,502,916 		JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO Melphalan results in decreased expression of LRIG3 mRNA CTD PMID:22363485 NCBI chr 7:69,213,098...69,263,251
Ensembl chr 7:69,213,147...69,263,142 		JBrowse link
G Lurap1 leucine rich adaptor protein 1 decreases expression ISO Melphalan results in decreased expression of LURAP1 mRNA CTD PMID:22363485 NCBI chr 5:134,991,997...135,001,720
Ensembl chr 5:134,991,997...135,001,720 		JBrowse link
G Lyst lysosomal trafficking regulator decreases expression ISO Melphalan results in decreased expression of LYST mRNA CTD PMID:22363485 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:16025434 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16025434 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Melphalan results in decreased expression of MBOAT1 mRNA CTD PMID:22363485 NCBI chr17:36,061,775...36,177,457
Ensembl chr17:36,061,775...36,177,457 		JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression ISO Melphalan results in decreased expression of MEOX2 mRNA CTD PMID:22363485 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238 		JBrowse link
G Mex3a mex-3 RNA binding family member A increases expression ISO Melphalan results in increased expression of MEX3A mRNA CTD PMID:22363485 NCBI chr 2:187,893,678...187,902,546
Ensembl chr 2:187,893,368...187,898,310 		JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO Melphalan results in increased expression of MEX3B mRNA CTD PMID:22363485 NCBI chr 1:144,831,523...144,835,758
Ensembl chr 1:144,831,523...144,835,747 		JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A increases expression ISO Melphalan results in increased expression of MFSD2A mRNA CTD PMID:22363485 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases response to substance ISO MGST2 protein results in decreased susceptibility to Melphalan CTD PMID:15779864 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Melphalan results in decreased expression of MITF mRNA CTD PMID:22363485 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit decreases expression ISO Melphalan results in decreased expression of MLLT3 mRNA CTD PMID:22363485 NCBI chr 5:106,103,498...106,202,559
Ensembl chr 5:106,103,407...106,207,126 		JBrowse link
G Mms22l MMS22-like, DNA repair protein decreases expression ISO Melphalan results in decreased expression of MMS22L mRNA CTD PMID:22363485 NCBI chr 5:38,844,502...38,960,989
Ensembl chr 5:38,844,488...38,961,035 		JBrowse link
G Mrtfb myocardin related transcription factor B decreases expression ISO Melphalan results in decreased expression of MRTFB mRNA CTD PMID:22363485 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Mta3 metastasis associated 1 family, member 3 decreases expression ISO Melphalan results in decreased expression of MTA3 mRNA CTD PMID:22363485 NCBI chr 6:6,904,449...7,036,929
Ensembl chr 6:6,908,684...7,031,828 		JBrowse link
G Mtcl1 microtubule crosslinking factor 1 decreases expression ISO Melphalan results in decreased expression of MTCL1 mRNA CTD PMID:22363485 NCBI chr 9:114,493,901...114,632,632
Ensembl chr 9:114,491,419...114,619,711 		JBrowse link
G Myo1b myosin Ib decreases expression ISO Melphalan results in decreased expression of MYO1B mRNA CTD PMID:22363485 NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054 		JBrowse link
G Nebl nebulette increases expression ISO Melphalan results in increased expression of NEBL mRNA CTD PMID:22363485 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601 		JBrowse link
G Nfia nuclear factor I/A decreases expression ISO Melphalan results in decreased expression of NFIA mRNA CTD PMID:22363485 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416 		JBrowse link
G Nhs NHS actin remodeling regulator decreases expression ISO Melphalan results in decreased expression of NHS mRNA CTD PMID:22363485 NCBI chr  X:34,312,102...34,675,912
Ensembl chr  X:34,623,405...34,673,742 		JBrowse link
G Nkrf NFKB repressing factor increases expression ISO Melphalan results in increased expression of NKRF mRNA CTD PMID:22363485 NCBI chr  X:123,502,074...123,516,301
Ensembl chr  X:123,502,096...123,515,720 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO Melphalan results in increased expression of NOP56 mRNA CTD PMID:22363485 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558 		JBrowse link
G Nppb natriuretic peptide B increases expression ISO Melphalan results in increased expression of NPPB protein CTD PMID:18548196 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Melphalan results in increased expression of NR4A3 mRNA CTD PMID:22363485 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
G Nrg2 neuregulin 2 decreases expression ISO Melphalan results in decreased expression of NRG2 mRNA CTD PMID:22363485 NCBI chr18:28,835,391...29,015,552
Ensembl chr18:28,835,417...29,015,552 		JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO Melphalan results in decreased expression of NRP1 mRNA CTD PMID:22363485 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858 		JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Melphalan results in decreased expression of NUAK1 mRNA CTD PMID:22363485 NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 decreases expression ISO Melphalan results in decreased expression of OSBPL10 mRNA CTD PMID:22363485 NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Melphalan results in decreased expression of PAG1 mRNA CTD PMID:22363485 NCBI chr 2:94,266,104...94,277,680
Ensembl chr 2:94,266,213...94,277,676 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Melphalan results in decreased expression of PDLIM5 mRNA CTD PMID:22363485 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462 		JBrowse link
G Phf21a PHD finger protein 21A decreases expression ISO Melphalan results in decreased expression of PHF21A mRNA CTD PMID:22363485 NCBI chr 3:81,099,765...81,271,841
Ensembl chr 3:81,134,505...81,271,849 		JBrowse link
G Phf3 PHD finger protein 3 decreases expression ISO Melphalan results in decreased expression of PHF3 mRNA CTD PMID:22363485 NCBI chr 9:37,073,514...37,144,027
Ensembl chr 9:37,073,514...37,144,015 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Melphalan results in increased expression of PHLDA1 mRNA CTD PMID:22363485 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression ISO Melphalan results in decreased expression of PHLDB2 mRNA CTD PMID:22363485 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis
multiple interactions		 EXP Melphalan results in increased mutagenesis of PIGA
Melphalan results in increased mutagenesis of and results in decreased activity of PIGA protein		 CTD PMID:22923490 PMID:27931811 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Melphalan results in decreased expression of PIK3R1 mRNA CTD PMID:22363485 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO Melphalan results in decreased expression of PIK3R3 mRNA CTD PMID:22363485 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488 		JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Melphalan results in decreased expression of PLCL2 mRNA CTD PMID:22363485 NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO Melphalan results in decreased expression of PLEKHA2 mRNA CTD PMID:22363485 NCBI chr16:71,725,649...71,784,432
Ensembl chr16:71,738,718...71,787,787 		JBrowse link
G Plekha5 pleckstrin homology domain containing A5 decreases expression ISO Melphalan results in decreased expression of PLEKHA5 mRNA CTD PMID:22363485 NCBI chr 4:174,605,462...174,774,692
Ensembl chr 4:174,605,476...174,774,693 		JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Melphalan results in increased expression of PLK3 mRNA CTD PMID:22363485 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900 		JBrowse link
G Ppif peptidylprolyl isomerase F increases expression ISO Melphalan results in increased expression of PPIF mRNA CTD PMID:22363485 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908 		JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H decreases expression ISO Melphalan results in decreased expression of PPM1H mRNA CTD PMID:22363485 NCBI chr 7:66,845,692...67,116,979
Ensembl chr 7:66,843,865...67,116,980 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Melphalan results in decreased expression of PPP2R2B mRNA CTD PMID:22363485 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha decreases expression ISO Melphalan results in decreased expression of PPP2R5A mRNA CTD PMID:22363485 NCBI chr13:110,033,550...110,077,946
Ensembl chr13:110,033,550...110,077,946 		JBrowse link
G Prune2 prune homolog 2 with BCH domain decreases expression ISO Melphalan results in decreased expression of PRUNE2 mRNA CTD PMID:22363485 NCBI chr 1:236,676,963...236,947,527
Ensembl chr 1:236,680,098...236,729,412 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 decreases expression ISO Melphalan results in decreased expression of PSD3 mRNA CTD PMID:22363485 NCBI chr16:23,212,165...23,789,414
Ensembl chr16:23,447,366...23,781,604 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Melphalan results in increased expression of PTGS2 mRNA CTD PMID:22363485 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Melphalan results in decreased expression of PTPRG mRNA CTD PMID:22363485 NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607 		JBrowse link
G Pxk PX domain containing serine/threonine kinase decreases expression ISO Melphalan results in decreased expression of PXK mRNA CTD PMID:22363485 NCBI chr15:18,548,209...18,616,617
Ensembl chr15:18,548,212...18,616,589 		JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO Melphalan results in decreased expression of RAD54B mRNA CTD PMID:22363485 NCBI chr 5:25,140,531...25,214,469
Ensembl chr 5:25,146,949...25,214,376 		JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked decreases expression ISO Melphalan results in decreased expression of RADX mRNA CTD PMID:22363485 NCBI chr  X:110,670,037...110,782,420
Ensembl chr  X:110,670,119...110,782,284 		JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO Melphalan results in decreased expression of RARB mRNA CTD PMID:22363485 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO Melphalan results in increased expression of RASD1 mRNA CTD PMID:22363485 NCBI chr10:46,330,361...46,339,326
Ensembl chr10:46,330,368...46,332,172 		JBrowse link
G Rasl10a RAS-like, family 10, member A increases expression ISO Melphalan results in increased expression of RASL10A mRNA CTD PMID:22363485 NCBI chr14:85,311,833...85,313,211
Ensembl chr14:85,311,089...85,314,270 		JBrowse link
G Rasl11b RAS-like family 11 member B increases expression ISO Melphalan results in increased expression of RASL11B mRNA CTD PMID:22363485 NCBI chr14:36,550,353...36,554,574
Ensembl chr14:36,550,340...36,554,580 		JBrowse link
G Rbm24 RNA binding motif protein 24 increases expression ISO Melphalan results in increased expression of RBM24 mRNA CTD PMID:22363485 NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit decreases expression ISO Melphalan results in decreased expression of REV3L mRNA CTD PMID:22363485 NCBI chr20:44,803,664...44,961,362
Ensembl chr20:44,803,666...44,961,382 		JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 decreases expression ISO Melphalan results in decreased expression of RGL1 mRNA CTD PMID:22363485 NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b decreases expression ISO Melphalan results in decreased expression of RGMB mRNA CTD PMID:22363485 NCBI chr 1:57,794,046...57,819,941
Ensembl chr 1:57,796,709...57,815,038 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Melphalan results in increased expression of RGS16 mRNA CTD PMID:22363485 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Melphalan results in increased expression of RGS2 mRNA CTD PMID:22363485 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 decreases expression ISO Melphalan results in decreased expression of RIPOR2 mRNA CTD PMID:22363485 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053 		JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Melphalan results in decreased expression of RNF128 mRNA CTD PMID:22363485 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978 		JBrowse link
G Rnf144b ring finger protein 144B decreases expression ISO Melphalan results in decreased expression of RNF144B mRNA CTD PMID:22363485 NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO Melphalan results in decreased expression of ROR1 mRNA CTD PMID:22363485 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733 		JBrowse link
G Rpl27a ribosomal protein L27a increases expression ISO Melphalan results in increased expression of RPL27A mRNA CTD PMID:22363485 NCBI chr 1:174,132,798...174,135,816
Ensembl chr 1:174,132,798...174,135,816 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Melphalan results in increased expression of RRAD mRNA CTD PMID:22363485 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930 		JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Melphalan results in decreased expression of RSPO2 mRNA CTD PMID:22363485 NCBI chr 7:81,919,911...82,059,659
Ensembl chr 7:81,924,050...82,059,789 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 decreases expression ISO Melphalan results in decreased expression of RUNX1T1 mRNA CTD PMID:22363485 NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 decreases expression ISO Melphalan results in decreased expression of SCN8A mRNA CTD PMID:22363485 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114 		JBrowse link
G Sema6d semaphorin 6D decreases expression ISO Melphalan results in decreased expression of SEMA6D mRNA CTD PMID:22363485 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Melphalan results in increased expression of SERPINB2 mRNA CTD PMID:22363485 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Melphalan results in increased expression of SGK1 mRNA CTD PMID:22363485 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO Melphalan results in decreased expression of SGMS1 mRNA CTD PMID:22363485 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 decreases expression ISO Melphalan results in decreased expression of SHANK2 mRNA CTD PMID:22363485 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763 		JBrowse link
G Shroom3 shroom family member 3 decreases expression ISO Melphalan results in decreased expression of SHROOM3 mRNA CTD PMID:22363485 NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Melphalan results in increased expression of SIK1 mRNA CTD PMID:22363485 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO Melphalan results in decreased expression of SLC14A1 mRNA CTD PMID:22363485 NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139 		JBrowse link
G Slc19a2 solute carrier family 19 member 2 increases expression ISO Melphalan results in increased expression of SLC19A2 mRNA CTD PMID:22363485 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation		 ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Melphalan results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078 		JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO Melphalan results in decreased expression of SMAD3 mRNA CTD PMID:22363485 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Sntb1 syntrophin, beta 1 decreases expression ISO Melphalan results in decreased expression of SNTB1 mRNA CTD PMID:22363485 NCBI chr 7:95,395,417...95,670,093
Ensembl chr 7:95,397,113...95,669,809 		JBrowse link
G Snx29 sorting nexin 29 decreases expression ISO Melphalan results in decreased expression of SNX29 mRNA CTD PMID:22363485 NCBI chr10:3,838,444...4,249,741
Ensembl chr10:3,840,622...4,249,739 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression ISO Melphalan results in decreased expression of SOCS5 mRNA CTD PMID:22363485 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977 		JBrowse link
G Spata17 spermatogenesis associated 17 decreases expression ISO Melphalan results in decreased expression of SPATA17 mRNA CTD PMID:22363485 NCBI chr13:105,489,121...105,684,293
Ensembl chr13:105,489,074...105,684,374 		JBrowse link
G Spata7 spermatogenesis associated 7 decreases expression ISO Melphalan results in decreased expression of SPATA7 mRNA CTD PMID:22363485 NCBI chr 6:122,603,248...122,648,718
Ensembl chr 6:122,603,269...122,648,699 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 decreases expression ISO Melphalan results in decreased expression of SPRED1 mRNA CTD PMID:22363485 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 increases expression ISO Melphalan results in increased expression of SPTY2D1 mRNA CTD PMID:22363485 NCBI chr 1:103,115,280...103,129,438
Ensembl chr 1:103,115,216...103,128,743 		JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO Melphalan results in decreased expression of SRGAP2 mRNA CTD PMID:22363485 NCBI chr13:48,065,280...48,286,888
Ensembl chr13:48,068,158...48,286,720 		JBrowse link
G Stac SH3 and cysteine rich domain decreases expression ISO Melphalan results in decreased expression of STAC mRNA CTD PMID:22363485 NCBI chr 8:119,820,664...119,941,867
Ensembl chr 8:119,821,901...119,889,661 		JBrowse link
G Stambpl1 STAM binding protein-like 1 decreases expression ISO Melphalan results in decreased expression of STAMBPL1 mRNA CTD PMID:22363485 NCBI chr 1:252,490,125...252,536,113
Ensembl chr 1:252,497,452...252,536,104 		JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO Melphalan results in decreased expression of TACC2 mRNA CTD PMID:22363485 NCBI chr 1:201,140,264...201,329,612
Ensembl chr 1:201,055,644...201,329,622 		JBrowse link
G Tbc1d12 TBC1 domain family, member 12 decreases expression ISO Melphalan results in decreased expression of TBC1D12 mRNA CTD PMID:22363485 NCBI chr 1:257,517,128...257,599,659
Ensembl chr 1:257,517,242...257,883,971 		JBrowse link
G Tbl1xr1 TBL1X receptor 1 decreases expression ISO Melphalan results in decreased expression of TBL1XR1 mRNA CTD PMID:22363485 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression ISO Melphalan results in decreased expression of TET1 mRNA CTD PMID:22363485 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427 		JBrowse link
G Tex30 testis expressed 30 increases expression ISO Melphalan results in increased expression of TEX30 mRNA CTD PMID:22363485 NCBI chr 9:50,858,737...50,868,238
Ensembl chr 9:50,858,737...50,868,238 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Melphalan results in increased expression of TFPI2 mRNA CTD PMID:22363485 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa] CTD PMID:9509296 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 decreases expression ISO Melphalan results in decreased expression of THSD4 mRNA CTD PMID:22363485 NCBI chr 8:64,811,940...65,413,498
Ensembl chr 8:64,817,191...65,003,296 		JBrowse link
G Tigd2 tigger transposable element derived 2 decreases expression ISO Melphalan results in decreased expression of TIGD2 mRNA CTD PMID:22363485 NCBI chr 4:89,535,418...89,538,535
Ensembl chr 4:89,536,647...89,538,227 		JBrowse link
G Tlnrd1 talin rod domain containing 1 increases expression ISO Melphalan results in increased expression of TLNRD1 mRNA CTD PMID:22363485 NCBI chr 1:146,027,821...146,029,840
Ensembl chr 1:146,027,822...146,029,840 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Melphalan results in decreased expression of TLR4 mRNA CTD PMID:22363485 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tmem131l transmembrane 131 like decreases expression ISO Melphalan results in decreased expression of TMEM131L mRNA CTD PMID:22363485 NCBI chr 2:182,897,332...183,031,273
Ensembl chr 2:182,897,830...183,031,214 		JBrowse link
G Tmem200a transmembrane protein 200A decreases expression ISO Melphalan results in decreased expression of TMEM200A mRNA CTD PMID:22363485 NCBI chr 1:20,330,670...20,413,921
Ensembl chr 1:20,331,976...20,412,381 		JBrowse link
G Tmem26 transmembrane protein 26 decreases expression ISO Melphalan results in decreased expression of TMEM26 mRNA CTD PMID:22363485 NCBI chr20:21,640,655...21,689,655
Ensembl chr20:21,642,484...21,689,553 		JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Melphalan results in increased expression of TMEM88 mRNA CTD PMID:22363485 NCBI chr10:55,998,530...56,000,225
Ensembl chr10:55,998,530...56,000,225 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Melphalan results in increased expression of TNF mRNA CTD PMID:16025434 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases expression ISO Melphalan results in decreased expression of TNFRSF19 mRNA CTD PMID:22363485 NCBI chr15:41,249,820...41,316,203
Ensembl chr15:41,246,308...41,338,284 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Melphalan results in increased expression of TNNI3 protein CTD PMID:18548196 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488 		JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B decreases expression ISO Melphalan results in decreased expression of TNRC6B mRNA CTD PMID:22363485 NCBI chr 7:121,930,610...122,147,934
Ensembl chr 7:121,930,615...122,147,934 		JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression ISO Melphalan results in decreased expression of TOX mRNA CTD PMID:22363485 NCBI chr 5:19,892,698...20,189,721
Ensembl chr 5:19,892,698...20,189,721 		JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Melphalan results in decreased expression of TP63 mRNA CTD PMID:22363485 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501 		JBrowse link
G Trerf1 transcriptional regulating factor 1 decreases expression ISO Melphalan results in decreased expression of TRERF1 mRNA CTD PMID:22363485 NCBI chr 9:15,653,230...15,881,695
Ensembl chr 9:15,655,735...15,700,312 		JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Melphalan results in increased expression of TRIB1 mRNA CTD PMID:22363485 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit increases expression ISO Melphalan results in increased expression of TRMT10C mRNA CTD PMID:22363485 NCBI chr11:47,047,342...47,052,420
Ensembl chr11:47,047,342...47,052,418 		JBrowse link
G Ttc30b tetratricopeptide repeat domain 30B decreases expression ISO Melphalan results in decreased expression of TTC30B mRNA CTD PMID:22363485 NCBI chr 3:62,758,754...62,761,325
Ensembl chr 3:62,758,758...62,761,325 		JBrowse link
G Tubg1 tubulin, gamma 1 increases expression ISO Melphalan results in increased expression of TUBG1 protein CTD PMID:22025197 NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Melphalan results in increased expression of TUFT1 mRNA CTD PMID:22363485 NCBI chr 2:195,861,772...195,907,471
Ensembl chr 2:195,861,649...195,908,037 		JBrowse link
G Twnk twinkle mtDNA helicase increases expression ISO Melphalan results in increased expression of TWNK mRNA CTD PMID:22363485 NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Melphalan results in decreased activity of TXNRD1 protein CTD PMID:16085187 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400 		JBrowse link
G Ubap1l ubiquitin associated protein 1-like increases expression ISO Melphalan results in increased expression of UBAP1L mRNA CTD PMID:22363485 NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Melphalan results in increased expression of USP36 mRNA CTD PMID:22363485 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355 		JBrowse link
G Usp53 ubiquitin specific peptidase 53 decreases expression ISO Melphalan results in decreased expression of USP53 mRNA CTD PMID:22363485 NCBI chr 2:227,098,795...227,160,385
Ensembl chr 2:227,098,795...227,160,379 		JBrowse link
G Utp25 UTP25, small subunit processor component increases expression ISO Melphalan results in increased expression of UTP25 mRNA CTD PMID:22363485 NCBI chr13:111,828,052...111,849,654
Ensembl chr13:111,828,043...111,849,653 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [arsenic trioxide results in increased expression of VDAC1 protein] which results in increased susceptibility to Melphalan CTD PMID:22285227 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826 		JBrowse link
G Yod1 YOD1 deubiquitinase increases expression ISO Melphalan results in increased expression of YOD1 mRNA CTD PMID:22363485 NCBI chr13:47,441,296...47,443,013
Ensembl chr13:47,440,803...47,443,188 		JBrowse link
G Ypel2 yippee-like 2 decreases expression ISO Melphalan results in decreased expression of YPEL2 mRNA CTD PMID:22363485 NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing increases expression ISO Melphalan results in increased expression of YRDC mRNA CTD PMID:22363485 NCBI chr 5:142,845,265...142,850,110
Ensembl chr 5:142,845,114...142,850,111 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression ISO Melphalan results in decreased expression of ZBTB20 mRNA CTD PMID:22363485 NCBI chr11:62,014,925...62,561,113
Ensembl chr11:62,014,925...62,451,184 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Melphalan results in increased expression of ZC3H12A mRNA CTD PMID:22363485 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165 		JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Melphalan results in decreased expression of ZFHX4 mRNA CTD PMID:22363485 NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368 		JBrowse link
G Zfp277 zinc finger protein 277 decreases expression ISO Melphalan results in decreased expression of ZNF277 mRNA CTD PMID:22363485 NCBI chr 6:60,246,209...60,374,388
Ensembl chr 6:60,246,214...60,374,389 		JBrowse link
G Zfp438 zinc finger protein 438 decreases expression ISO Melphalan results in decreased expression of ZNF438 mRNA CTD PMID:22363485 NCBI chr17:55,006,893...55,131,567
Ensembl chr17:55,008,265...55,129,555 		JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO Melphalan results in decreased expression of ZNF521 mRNA CTD PMID:22363485 NCBI chr18:5,022,042...5,315,242
Ensembl chr18:5,032,029...5,314,585 		JBrowse link
G Zfp618 zinc finger protein 618 decreases expression ISO Melphalan results in decreased expression of ZNF618 mRNA CTD PMID:22363485 NCBI chr 5:78,806,585...78,972,433
Ensembl chr 5:78,806,607...78,966,813 		JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO Melphalan results in decreased expression of ZSWIM5 mRNA CTD PMID:22363485 NCBI chr 5:135,735,825...135,854,525
Ensembl chr 5:135,735,825...135,852,575 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        immunomodulator 14883
          immunosuppressive agent 13701
            melphalan 271
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18075
                                  cyclic hydrocarbon 17090
                                    monocyclic hydrocarbon 5811
                                      annulene 5637
                                        aromatic annulene 5637
                                          benzene 5637
                                            alkylbenzene 3360
                                              methylbenzene 3225
                                                toluene 3089
                                                  benzyl group 2500
                                                    phenylalanine 2500
                                                      L-phenylalanine 2247
                                                        L-phenylalanine derivative 2234
                                                          melphalan 271
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