CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: melphalan
Accession: CHEBI:28876
browse the term
Definition: A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Synonyms: related_synonym: 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine; 4-(Bis(2-chloroethyl)amino)-L-phenylalanine; Formula=C13H18Cl2N2O2; InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1; InChIKey=SGDBTWWWUNNDEQ-LBPRGKRZSA-N; L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine; L-PAM; L-Phenylalanine mustard; L-Sarcolysine; Phenylalanine mustard; Phenylalanine nitrogen mustard; SMILES=N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O; melfalano; melphalanum; p-Bis(beta-chloroethyl)aminophenylalanine; p-Di-(2-chloroethyl)amino-L-phenylalanine; p-L-Sarcolysin; p-N,N-bis(2-chloroethyl)amino-L-phenylalanine; p-N-Bis(2-chloroethyl)amino-L-phenylalanine
alt_id: CHEBI:25815; CHEBI:6742
xref: CAS:148-82-3; DrugBank:DB01042; Drug_Central:1678; KEGG:D00369
xref_mesh: MESH:D008558
xref: PMID:10820424; PMID:10937717; PMID:11680815; PMID:11914777; PMID:18481314; PMID:445303; PMID:7494795; PMID:7605343; PMID:8552138; PMID:8951232; PMID:9218926; PMID:9250538; Patent:US108552; Patent:US275057; Patent:US3032584; Patent:US3032585; Reaxys:2816456; Wikipedia:Melphalan
G
Abcc1
ATP binding cassette subfamily C member 1
affects export
ISO
ABCC1 protein affects the export of Melphalan analog
CTD
PMID:11115505
NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
G
Abhd17c
abhydrolase domain containing 17C, depalmitoylase
decreases expression
ISO
Melphalan results in decreased expression of ABHD17C mRNA
CTD
PMID:22363485
NCBI chr 1:146,248,505...146,289,465
Ensembl chr 1:146,248,503...146,289,465
G
Abraxas1
abraxas 1, BRCA1 A complex subunit
decreases expression
ISO
Melphalan results in decreased expression of ABRAXAS1 mRNA
CTD
PMID:22363485
NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003
G
Abt1
activator of basal transcription 1
increases expression
ISO
Melphalan results in increased expression of ABT1 mRNA
CTD
PMID:22363485
NCBI chr17:43,946,118...43,948,224
Ensembl chr17:43,946,130...43,948,223
G
Ackr3
atypical chemokine receptor 3
increases expression
ISO
Melphalan results in increased expression of ACKR3 mRNA
CTD
PMID:22363485
NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
G
Acvr1c
activin A receptor type 1C
decreases expression
ISO
Melphalan results in decreased expression of ACVR1C mRNA
CTD
PMID:22363485
NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
G
Ahrr
aryl-hydrocarbon receptor repressor
decreases expression
ISO
Melphalan results in decreased expression of AHRR mRNA
CTD
PMID:22363485
NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
G
Alad
aminolevulinate dehydratase
decreases activity
ISO
Melphalan results in decreased activity of ALAD protein
CTD
PMID:19162187
NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
G
Ammecr1l
AMMECR1 like
increases expression
ISO
Melphalan results in increased expression of AMMECR1L mRNA
CTD
PMID:22363485
NCBI chr18:24,539,530...24,563,576
Ensembl chr18:24,540,659...24,563,576
G
Ankar
ankyrin and armadillo repeat containing
decreases expression
ISO
Melphalan results in decreased expression of ANKAR mRNA
CTD
PMID:22363485
NCBI chr 9:53,011,561...53,086,178
Ensembl chr 9:53,013,413...53,084,010
G
Ankrd10
ankyrin repeat domain 10
increases expression
ISO
Melphalan results in increased expression of ANKRD10 mRNA
CTD
PMID:22363485
NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
G
Ankrd28
ankyrin repeat domain 28
decreases expression
ISO
Melphalan results in decreased expression of ANKRD28 mRNA
CTD
PMID:22363485
NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
G
Ankrd34a
ankyrin repeat domain 34A
decreases expression
ISO
Melphalan results in decreased expression of ANKRD34A mRNA
CTD
PMID:22363485
NCBI chr 2:198,720,277...198,725,155
Ensembl chr 2:198,721,724...198,725,154
G
Ar
androgen receptor
decreases expression
ISO
Melphalan results in decreased expression of AR mRNA
CTD
PMID:22363485
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
G
Arhgap12
Rho GTPase activating protein 12
decreases expression
ISO
Melphalan results in decreased expression of ARHGAP12 mRNA
CTD
PMID:22363485
NCBI chr17:54,280,815...54,394,716
Ensembl chr17:54,280,851...54,394,634
G
Arhgap18
Rho GTPase activating protein 18
decreases expression
ISO
Melphalan results in decreased expression of ARHGAP18 mRNA
CTD
PMID:22363485
NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
G
Arhgap20
Rho GTPase activating protein 20
decreases expression
ISO
Melphalan results in decreased expression of ARHGAP20 mRNA
CTD
PMID:22363485
NCBI chr 8:56,179,581...56,264,343
Ensembl chr 8:56,179,637...56,264,263
G
Arhgap24
Rho GTPase activating protein 24
decreases expression
ISO
Melphalan results in decreased expression of ARHGAP24 mRNA
CTD
PMID:22363485
NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
G
Arhgap42
Rho GTPase activating protein 42
decreases expression
ISO
Melphalan results in decreased expression of ARHGAP42 mRNA
CTD
PMID:22363485
NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
G
Arid5a
AT-rich interaction domain 5A
increases expression
ISO
Melphalan results in increased expression of ARID5A mRNA
CTD
PMID:22363485
NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
G
Atg16l1
autophagy related 16-like 1
increases expression
ISO
Melphalan results in increased expression of ATG16L1 mRNA
CTD
PMID:22363485
NCBI chr 9:94,879,876...94,915,231
Ensembl chr 9:94,879,745...94,915,228
G
Atp2b1
ATPase plasma membrane Ca2+ transporting 1
decreases expression
ISO
Melphalan results in decreased expression of ATP2B1 mRNA
CTD
PMID:22363485
NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
G
Aurka
aurora kinase A
increases expression
ISO
Melphalan results in increased expression of AURKA protein
CTD
PMID:22025197
NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
G
Aurkb
aurora kinase B
decreases expression
ISO
Melphalan results in decreased expression of AURKB protein
CTD
PMID:22025197
NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
G
B3gnt2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
increases expression
ISO
Melphalan results in increased expression of B3GNT2 mRNA
CTD
PMID:22363485
NCBI chr14:107,592,336...107,617,189
Ensembl chr14:107,592,336...107,617,161
G
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
increases expression
ISO
Melphalan results in increased expression of B3GNT5 mRNA
CTD
PMID:22363485
NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160
G
Bak1
BCL2-antagonist/killer 1
increases expression
ISO
Melphalan results in increased expression of BAK1 protein
CTD
PMID:22285227
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
Melphalan results in increased expression of and results in decreased localization of BAX protein
CTD
PMID:22285227
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
G
Bche
butyrylcholinesterase
multiple interactions
ISO
[Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein
CTD
PMID:4672170
NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
Melphalan results in decreased expression of BCL2 protein
CTD
PMID:22285227
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
G
Bcl2a1
BCL2-related protein A1
increases expression
ISO
Melphalan results in increased expression of BCL2A1 mRNA
CTD
PMID:22363485
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
G
Bicc1
BicC family RNA binding protein 1
decreases expression
ISO
Melphalan results in decreased expression of BICC1 mRNA
CTD
PMID:22363485
NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408
G
Bicdl2
BICD family like cargo adaptor 2
increases expression
ISO
Melphalan results in increased expression of BICDL2 mRNA
CTD
PMID:22363485
NCBI chr10:12,980,696...12,989,133
Ensembl chr10:12,980,674...12,992,780
G
Birc5
baculoviral IAP repeat-containing 5
affects response to substance decreases expression multiple interactions
ISO
BIRC5 protein affects the susceptibility to Melphalan Melphalan results in decreased expression of BIRC5 protein Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]; Paclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]
CTD
PMID:16373717 PMID:22025197
NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
G
Bnc2
basonuclin 2
decreases expression
ISO
Melphalan results in decreased expression of BNC2 mRNA
CTD
PMID:22363485
NCBI chr 5:102,407,508...102,807,389
Ensembl chr 5:102,415,847...102,786,331
G
Btbd8
BTB domain containing 8
decreases expression
ISO
Melphalan results in decreased expression of BTBD8 mRNA
CTD
PMID:22363485
NCBI chr14:3,282,422...3,351,740
Ensembl chr14:3,284,089...3,300,200
G
Btg2
BTG anti-proliferation factor 2
increases expression
ISO
Melphalan results in increased expression of BTG2 mRNA
CTD
PMID:22363485
NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
G
Cables1
Cdk5 and Abl enzyme substrate 1
decreases expression
ISO
Melphalan results in decreased expression of CABLES1 mRNA
CTD
PMID:22363485
NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
G
Casp3
caspase 3
increases activity
ISO
Melphalan results in increased activity of CASP3 protein
CTD
PMID:16951922
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
G
Casp9
caspase 9
multiple interactions
ISO
Melphalan results in increased cleavage of and results in increased activity of CASP9 protein
CTD
PMID:22285227
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
G
Cat
catalase
decreases activity
ISO
Melphalan results in decreased activity of CAT protein
CTD
PMID:19162187
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
G
Cc2d2a
coiled-coil and C2 domain containing 2A
decreases expression
ISO
Melphalan results in decreased expression of CC2D2A mRNA
CTD
PMID:22363485
NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419
G
Ccdc110
coiled-coil domain containing 110
decreases expression
ISO
Melphalan results in decreased expression of CCDC110 mRNA
CTD
PMID:22363485
NCBI chr16:49,509,885...49,522,094
Ensembl chr16:49,509,876...49,522,341 Ensembl chr16:49,509,876...49,522,341
G
Ccdc171
coiled-coil domain containing 171
decreases expression
ISO
Melphalan results in decreased expression of CCDC171 mRNA
CTD
PMID:22363485
NCBI chr 5:101,639,355...102,017,300
G
Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
Melphalan results in increased expression of CCL20 mRNA
CTD
PMID:22363485
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
G
Ccnj
cyclin J
increases expression
ISO
Melphalan results in increased expression of CCNJ mRNA
CTD
PMID:22363485
NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254 Ensembl chr 1:260,093,641...260,111,254
G
Cd34
CD34 molecule
multiple interactions
ISO
[Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein
CTD
PMID:10618687
NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
G
Cd59
CD59 molecule
decreases lipidation
EXP
Melphalan results in decreased lipidation of CD59 protein
CTD
PMID:27931811
NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
G
Cda
cytidine deaminase
decreases response to substance
ISO
CDA protein results in decreased susceptibility to Melphalan
CTD
PMID:10830723
NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541 Ensembl chr 5:156,703,579...156,734,541
G
Cdc14b
cell division cycle 14B
decreases expression
ISO
Melphalan results in decreased expression of CDC14B mRNA
CTD
PMID:22363485
NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
G
Cdc42ep3
CDC42 effector protein 3
decreases expression
ISO
Melphalan results in decreased expression of CDC42EP3 mRNA
CTD
PMID:22363485
NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
G
Cfap206
cilia and flagella associated protein 206
decreases expression
ISO
Melphalan results in decreased expression of CFAP206 mRNA
CTD
PMID:22363485
NCBI chr 5:50,148,685...50,193,580
Ensembl chr 5:50,148,658...50,193,571
G
Chek1
checkpoint kinase 1
increases phosphorylation
ISO
Melphalan results in increased phosphorylation of CHEK1 protein
CTD
PMID:26208482
NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
G
Chek2
checkpoint kinase 2
increases phosphorylation
ISO
Melphalan results in increased phosphorylation of CHEK2 protein
CTD
PMID:26208482
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
G
Chuk
component of inhibitor of nuclear factor kappa B kinase complex
affects phosphorylation
ISO
Melphalan affects the phosphorylation of CHUK protein
CTD
PMID:19934314
NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
G
Ciita
class II, major histocompatibility complex, transactivator
decreases expression
ISO
Melphalan results in decreased expression of CIITA mRNA
CTD
PMID:22363485
NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
G
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
increases expression
ISO
Melphalan results in increased expression of CITED4 mRNA
CTD
PMID:22363485
NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
G
Cnksr3
Cnksr family member 3
decreases expression
ISO
Melphalan results in decreased expression of CNKSR3 mRNA
CTD
PMID:22363485
NCBI chr 1:43,789,797...43,884,267
Ensembl chr 1:43,789,791...43,884,267
G
Cpne8
copine 8
decreases expression
ISO
Melphalan results in decreased expression of CPNE8 mRNA
CTD
PMID:22363485
NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
G
Creb5
cAMP responsive element binding protein 5
decreases expression
ISO
Melphalan results in decreased expression of CREB5 mRNA
CTD
PMID:22363485
NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
G
Cul3
cullin 3
increases expression
ISO
Melphalan results in increased expression of CUL3 mRNA
CTD
PMID:22363485
NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
G
Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
ISO
Melphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 protein
CTD
PMID:22363485
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO EXP
Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD
PMID:18493746
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions
ISO EXP
Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CTD
PMID:18493746
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression
ISO
Melphalan results in increased expression of CYP27B1 mRNA
CTD
PMID:22363485
NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
G
Cyria
CYFIP related Rac1 interactor A
decreases expression
ISO
Melphalan results in decreased expression of CYRIA mRNA
CTD
PMID:22363485
NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
G
Dbf4
DBF4 zinc finger
increases expression
ISO
Melphalan results in increased expression of DBF4 mRNA
CTD
PMID:22363485
NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
G
Dcn
decorin
multiple interactions
ISO
DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]
CTD
PMID:9509296
NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
G
Dennd4c
DENN domain containing 4C
decreases expression
ISO
Melphalan results in decreased expression of DENND4C mRNA
CTD
PMID:22363485
NCBI chr 5:105,100,081...105,195,634
Ensembl chr 5:105,114,433...105,193,988
G
Dlg3
discs large MAGUK scaffold protein 3
decreases expression
ISO
Melphalan results in decreased expression of DLG3 mRNA
CTD
PMID:22363485
NCBI chr X:70,596,246...70,648,529
Ensembl chr X:70,596,576...70,648,532
G
Dst
dystonin
decreases expression
ISO
Melphalan results in decreased expression of DST mRNA
CTD
PMID:22363485
NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
G
Dusp2
dual specificity phosphatase 2
increases expression
ISO
Melphalan results in increased expression of DUSP2 mRNA
CTD
PMID:22363485
NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
G
Eaf1
ELL associated factor 1
increases expression
ISO
Melphalan results in increased expression of EAF1 mRNA
CTD
PMID:22363485
NCBI chr16:7,588,217...7,602,966
Ensembl chr16:7,588,217...7,602,966
G
Ebf1
EBF transcription factor 1
decreases expression
ISO
Melphalan results in decreased expression of EBF1 mRNA
CTD
PMID:22363485
NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209
G
Edn1
endothelin 1
increases expression
ISO
Melphalan results in increased expression of EDN1 protein
CTD
PMID:18548196
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
G
Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
decreases expression
ISO
Melphalan results in decreased expression of EEPD1 mRNA
CTD
PMID:22363485
NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
G
Efna2
ephrin A2
increases expression
ISO
Melphalan results in increased expression of EFNA2 mRNA
CTD
PMID:22363485
NCBI chr 7:12,382,636...12,393,266
Ensembl chr 7:12,382,636...12,393,266
G
Efna5
ephrin A5
decreases expression
ISO
Melphalan results in decreased expression of EFNA5 mRNA
CTD
PMID:22363485
NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
G
Emx2
empty spiracles homeobox 2
decreases expression
ISO
Melphalan results in decreased expression of EMX2 mRNA
CTD
PMID:22363485
NCBI chr 1:280,633,938...280,640,946
Ensembl chr 1:280,633,938...280,640,946
G
Enox1
ecto-NOX disulfide-thiol exchanger 1
decreases expression
ISO
Melphalan results in decreased expression of ENOX1 mRNA
CTD
PMID:22363485
NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511
G
Epha5
EPH receptor A5
decreases expression
ISO
Melphalan results in decreased expression of EPHA5 mRNA
CTD
PMID:22363485
NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227
G
Exoc6
exocyst complex component 6
decreases expression
ISO
Melphalan results in decreased expression of EXOC6 mRNA
CTD
PMID:22363485
NCBI chr 1:256,211,879...256,369,318
Ensembl chr 1:256,226,179...256,368,813
G
Fabp5
fatty acid binding protein 5
increases expression
ISO
Melphalan results in increased expression of FABP5 mRNA
CTD
PMID:22363485
NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
G
Fam110b
family with sequence similarity 110, member B
decreases expression
ISO
Melphalan results in decreased expression of FAM110B mRNA
CTD
PMID:22363485
NCBI chr 5:18,762,488...18,903,818
Ensembl chr 5:18,901,039...18,902,672
G
Fam90a1
family with sequence similarity 90, member A1
decreases expression
ISO
Melphalan results in decreased expression of FAM90A1 mRNA
CTD
PMID:22363485
NCBI chr16:75,001,033...75,016,173
G
Fancc
FA complementation group C
increases response to substance
ISO
FANCC protein results in increased susceptibility to Melphalan
CTD
PMID:16243825
NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
G
Fancg
FA complementation group G
increases response to substance
ISO
FANCG protein results in increased susceptibility to Melphalan
CTD
PMID:16243825
NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
G
Fat4
FAT atypical cadherin 4
decreases expression
ISO
Melphalan results in decreased expression of FAT4 mRNA
CTD
PMID:22363485
NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387 Ensembl chr 2:125,752,130...125,879,387
G
Fgd4
FYVE, RhoGEF and PH domain containing 4
decreases expression
ISO
Melphalan results in decreased expression of FGD4 mRNA
CTD
PMID:22363485
NCBI chr11:88,699,222...88,796,677
Ensembl chr11:88,699,222...88,796,677
G
Fgd6
FYVE, RhoGEF and PH domain containing 6
decreases expression
ISO
Melphalan results in decreased expression of FGD6 mRNA
CTD
PMID:22363485
NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
G
Fgf5
fibroblast growth factor 5
decreases expression
ISO
Melphalan results in decreased expression of FGF5 mRNA
CTD
PMID:22363485
NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
G
Fign
fidgetin, microtubule severing factor
decreases expression
ISO
Melphalan results in decreased expression of FIGN mRNA
CTD
PMID:22363485
NCBI chr 3:49,992,250...50,120,601
Ensembl chr 3:49,992,397...50,120,392
G
Fmn2
formin 2
decreases expression
ISO
Melphalan results in decreased expression of FMN2 mRNA
CTD
PMID:22363485
NCBI chr13:92,569,256...92,887,302
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Melphalan results in increased expression of FOSB mRNA
CTD
PMID:22363485
NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
G
Foxp2
forkhead box P2
decreases expression
ISO
Melphalan results in decreased expression of FOXP2 mRNA
CTD
PMID:22363485
NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
G
Frmd4a
FERM domain containing 4A
decreases expression
ISO
Melphalan results in decreased expression of FRMD4A mRNA
CTD
PMID:22363485
NCBI chr17:77,642,302...77,918,210
G
Frmd4b
FERM domain containing 4B
decreases expression
ISO
Melphalan results in decreased expression of FRMD4B mRNA
CTD
PMID:22363485
NCBI chr 4:129,658,137...129,984,735
Ensembl chr 4:129,658,840...129,846,642
G
Fry
FRY microtubule binding protein
decreases expression
ISO
Melphalan results in decreased expression of FRY mRNA
CTD
PMID:22363485
NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
G
Fut10
fucosyltransferase 10
decreases expression
ISO
Melphalan results in decreased expression of FUT10 mRNA
CTD
PMID:22363485
NCBI chr16:64,623,246...64,716,248
Ensembl chr16:64,631,264...64,716,224
G
Gab1
GRB2-associated binding protein 1
decreases expression
ISO
Melphalan results in decreased expression of GAB1 mRNA
CTD
PMID:22363485
NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008
G
Garem1
GRB2 associated regulator of MAPK1 subtype 1
decreases expression
ISO
Melphalan results in decreased expression of GAREM1 mRNA
CTD
PMID:22363485
NCBI chr18:14,982,604...15,007,245
Ensembl chr18:12,224,514...12,284,188
G
Gas1
growth arrest-specific 1
decreases expression
ISO
Melphalan results in decreased expression of GAS1 mRNA
CTD
PMID:22363485
NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
G
Gcnt1
glucosaminyl (N-acetyl) transferase 1
decreases expression
ISO
Melphalan results in decreased expression of GCNT1 mRNA
CTD
PMID:22363485
NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
G
Gli3
GLI family zinc finger 3
decreases expression
ISO
Melphalan results in decreased expression of GLI3 mRNA
CTD
PMID:22363485
NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
G
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
increases expression
ISO
Melphalan results in increased expression of GRIN2C mRNA
CTD
PMID:22363485
NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
G
Grk5
G protein-coupled receptor kinase 5
decreases expression
ISO
Melphalan results in decreased expression of GRK5 mRNA
CTD
PMID:22363485
NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
G
Gsta1
glutathione S-transferase alpha 1
decreases response to substance
EXP
GSTA3 protein results in decreased susceptibility to Melphalan
CTD
PMID:8860835 PMID:10215608 PMID:10830723
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
G
Gsta5
glutathione S-transferase alpha 5
decreases response to substance
EXP
GSTA5 protein results in decreased susceptibility to Melphalan
CTD
PMID:12076520
NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
G
Gstm1
glutathione S-transferase mu 1
decreases response to substance
ISO
GSTM1 protein results in decreased susceptibility to Melphalan
CTD
PMID:20067466
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
ISO
GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]; Melphalan inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
CTD
PMID:12791655 PMID:23769903
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
G
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
decreases expression
ISO
Melphalan results in decreased expression of HECW2 mRNA
CTD
PMID:22363485
NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
G
Hgf
hepatocyte growth factor
decreases expression
ISO
Melphalan results in decreased expression of HGF mRNA
CTD
PMID:22363485
NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
G
Hmga2
high mobility group AT-hook 2
decreases expression
ISO
Melphalan results in decreased expression of HMGA2 mRNA
CTD
PMID:22363485
NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
G
Hoxd1
homeo box D1
increases expression
ISO
Melphalan results in increased expression of HOXD1 mRNA
CTD
PMID:22363485
NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
G
Icam1
intercellular adhesion molecule 1
increases expression
ISO
Melphalan results in increased expression of ICAM1 protein
CTD
PMID:16025434
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
G
Ier3
immediate early response 3
increases expression
ISO
Melphalan results in increased expression of IER3 mRNA
CTD
PMID:22363485
NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
G
Ikbke
inhibitor of nuclear factor kappa B kinase subunit epsilon
decreases expression
ISO
Melphalan results in decreased expression of IKBKE mRNA
CTD
PMID:22363485
NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
G
Ikzf2
IKAROS family zinc finger 2
decreases expression
ISO
Melphalan results in decreased expression of IKZF2 mRNA
CTD
PMID:22363485
NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806
G
Il12a
interleukin 12A
increases expression
ISO
Melphalan results in increased expression of IL12A mRNA
CTD
PMID:22363485
NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
G
Il16
interleukin 16
decreases expression
ISO
Melphalan results in decreased expression of IL16 mRNA
CTD
PMID:22363485
NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
G
Il1b
interleukin 1 beta
multiple interactions increases expression
ISO
Melphalan results in increased expression of and results in increased secretion of IL1B protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein] Melphalan results in increased expression of IL1B mRNA
CTD
PMID:21129433 PMID:22363485
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
G
Il23a
interleukin 23 subunit alpha
increases expression multiple interactions
ISO
Melphalan results in increased expression of IL23A protein TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]
CTD
PMID:21129433
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
G
Il6
interleukin 6
multiple interactions
ISO
Melphalan results in increased expression of and results in increased secretion of IL6 protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]
CTD
PMID:21129433
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
G
Il7
interleukin 7
decreases expression
ISO
Melphalan results in decreased expression of IL7 mRNA
CTD
PMID:22363485
NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
G
Irf2
interferon regulatory factor 2
decreases expression
ISO
Melphalan results in decreased expression of IRF2 mRNA
CTD
PMID:22363485
NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932
G
Jade2
jade family PHD finger 2
decreases expression
ISO
Melphalan results in decreased expression of JADE2 mRNA
CTD
PMID:22363485
NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625
G
Jak2
Janus kinase 2
decreases expression
ISO
Melphalan results in decreased expression of JAK2 mRNA
CTD
PMID:22363485
NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
G
Jakmip3
janus kinase and microtubule interacting protein 3
decreases expression
ISO
Melphalan results in decreased expression of JAKMIP3 mRNA
CTD
PMID:22363485
NCBI chr 1:211,292,604...211,421,023
Ensembl chr 1:211,351,350...211,421,022
G
Kalrn
kalirin, RhoGEF kinase
decreases expression
ISO
Melphalan results in decreased expression of KALRN mRNA
CTD
PMID:22363485
NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
G
Kbtbd3
kelch repeat and BTB domain containing 3
decreases expression
ISO
Melphalan results in decreased expression of KBTBD3 mRNA
CTD
PMID:22363485
NCBI chr 8:1,450,345...1,477,250
Ensembl chr 8:1,459,526...1,476,837
G
Kitlg
KIT ligand
decreases expression
ISO
Melphalan results in decreased expression of KITLG mRNA
CTD
PMID:22363485
NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
G
Klf12
Kruppel-like factor 12
decreases expression
ISO
Melphalan results in decreased expression of KLF12 mRNA
CTD
PMID:22363485
NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
G
Klhl42
kelch-like family, member 42
increases expression
ISO
Melphalan results in increased expression of KLHL42 mRNA
CTD
PMID:22363485
NCBI chr 4:181,481,147...181,502,916
Ensembl chr 4:181,481,147...181,502,916
G
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
decreases expression
ISO
Melphalan results in decreased expression of LRIG3 mRNA
CTD
PMID:22363485
NCBI chr 7:69,213,098...69,263,251
Ensembl chr 7:69,213,147...69,263,142
G
Lurap1
leucine rich adaptor protein 1
decreases expression
ISO
Melphalan results in decreased expression of LURAP1 mRNA
CTD
PMID:22363485
NCBI chr 5:134,991,997...135,001,720
Ensembl chr 5:134,991,997...135,001,720
G
Lyst
lysosomal trafficking regulator
decreases expression
ISO
Melphalan results in decreased expression of LYST mRNA
CTD
PMID:22363485
NCBI chr17:90,323,055...90,522,091
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Melphalan results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD
PMID:16025434
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Melphalan results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD
PMID:16025434
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
G
Mboat1
membrane bound O-acyltransferase domain containing 1
decreases expression
ISO
Melphalan results in decreased expression of MBOAT1 mRNA
CTD
PMID:22363485
NCBI chr17:36,061,775...36,177,457
Ensembl chr17:36,061,775...36,177,457
G
Meox2
mesenchyme homeobox 2
decreases expression
ISO
Melphalan results in decreased expression of MEOX2 mRNA
CTD
PMID:22363485
NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
G
Mex3a
mex-3 RNA binding family member A
increases expression
ISO
Melphalan results in increased expression of MEX3A mRNA
CTD
PMID:22363485
NCBI chr 2:187,893,678...187,902,546
Ensembl chr 2:187,893,368...187,898,310
G
Mex3b
mex-3 RNA binding family member B
increases expression
ISO
Melphalan results in increased expression of MEX3B mRNA
CTD
PMID:22363485
NCBI chr 1:144,831,523...144,835,758
Ensembl chr 1:144,831,523...144,835,747
G
Mfsd2a
major facilitator superfamily domain containing 2A
increases expression
ISO
Melphalan results in increased expression of MFSD2A mRNA
CTD
PMID:22363485
NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
G
Mgst2
microsomal glutathione S-transferase 2
decreases response to substance
ISO
MGST2 protein results in decreased susceptibility to Melphalan
CTD
PMID:15779864
NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
G
Mitf
melanocyte inducing transcription factor
decreases expression
ISO
Melphalan results in decreased expression of MITF mRNA
CTD
PMID:22363485
NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
G
Mllt3
MLLT3, super elongation complex subunit
decreases expression
ISO
Melphalan results in decreased expression of MLLT3 mRNA
CTD
PMID:22363485
NCBI chr 5:106,103,498...106,202,559
Ensembl chr 5:106,103,407...106,207,126
G
Mms22l
MMS22-like, DNA repair protein
decreases expression
ISO
Melphalan results in decreased expression of MMS22L mRNA
CTD
PMID:22363485
NCBI chr 5:38,844,502...38,960,989
Ensembl chr 5:38,844,488...38,961,035
G
Mrtfb
myocardin related transcription factor B
decreases expression
ISO
Melphalan results in decreased expression of MRTFB mRNA
CTD
PMID:22363485
NCBI chr10:1,151,163...1,273,269
G
Mta3
metastasis associated 1 family, member 3
decreases expression
ISO
Melphalan results in decreased expression of MTA3 mRNA
CTD
PMID:22363485
NCBI chr 6:6,904,449...7,036,929
Ensembl chr 6:6,908,684...7,031,828
G
Mtcl1
microtubule crosslinking factor 1
decreases expression
ISO
Melphalan results in decreased expression of MTCL1 mRNA
CTD
PMID:22363485
NCBI chr 9:114,493,901...114,632,632
Ensembl chr 9:114,491,419...114,619,711
G
Myo1b
myosin Ib
decreases expression
ISO
Melphalan results in decreased expression of MYO1B mRNA
CTD
PMID:22363485
NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054
G
Nebl
nebulette
increases expression
ISO
Melphalan results in increased expression of NEBL mRNA
CTD
PMID:22363485
NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
G
Nfia
nuclear factor I/A
decreases expression
ISO
Melphalan results in decreased expression of NFIA mRNA
CTD
PMID:22363485
NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
G
Nhs
NHS actin remodeling regulator
decreases expression
ISO
Melphalan results in decreased expression of NHS mRNA
CTD
PMID:22363485
NCBI chr X:34,312,102...34,675,912
Ensembl chr X:34,623,405...34,673,742
G
Nkrf
NFKB repressing factor
increases expression
ISO
Melphalan results in increased expression of NKRF mRNA
CTD
PMID:22363485
NCBI chr X:123,502,074...123,516,301
Ensembl chr X:123,502,096...123,515,720
G
Nop56
NOP56 ribonucleoprotein
increases expression
ISO
Melphalan results in increased expression of NOP56 mRNA
CTD
PMID:22363485
NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
G
Nppb
natriuretic peptide B
increases expression
ISO
Melphalan results in increased expression of NPPB protein
CTD
PMID:18548196
NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
Melphalan results in increased expression of NR4A3 mRNA
CTD
PMID:22363485
NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
G
Nrg2
neuregulin 2
decreases expression
ISO
Melphalan results in decreased expression of NRG2 mRNA
CTD
PMID:22363485
NCBI chr18:28,835,391...29,015,552
Ensembl chr18:28,835,417...29,015,552
G
Nrp1
neuropilin 1
decreases expression
ISO
Melphalan results in decreased expression of NRP1 mRNA
CTD
PMID:22363485
NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
G
Nuak1
NUAK family kinase 1
decreases expression
ISO
Melphalan results in decreased expression of NUAK1 mRNA
CTD
PMID:22363485
NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
G
Osbpl10
oxysterol binding protein-like 10
decreases expression
ISO
Melphalan results in decreased expression of OSBPL10 mRNA
CTD
PMID:22363485
NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
G
Pag1
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
decreases expression
ISO
Melphalan results in decreased expression of PAG1 mRNA
CTD
PMID:22363485
NCBI chr 2:94,266,104...94,277,680
Ensembl chr 2:94,266,213...94,277,676
G
Pdlim5
PDZ and LIM domain 5
decreases expression
ISO
Melphalan results in decreased expression of PDLIM5 mRNA
CTD
PMID:22363485
NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
G
Phf21a
PHD finger protein 21A
decreases expression
ISO
Melphalan results in decreased expression of PHF21A mRNA
CTD
PMID:22363485
NCBI chr 3:81,099,765...81,271,841
Ensembl chr 3:81,134,505...81,271,849
G
Phf3
PHD finger protein 3
decreases expression
ISO
Melphalan results in decreased expression of PHF3 mRNA
CTD
PMID:22363485
NCBI chr 9:37,073,514...37,144,027
Ensembl chr 9:37,073,514...37,144,015
G
Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
Melphalan results in increased expression of PHLDA1 mRNA
CTD
PMID:22363485
NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
G
Phldb2
pleckstrin homology-like domain, family B, member 2
decreases expression
ISO
Melphalan results in decreased expression of PHLDB2 mRNA
CTD
PMID:22363485
NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589
G
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
increases mutagenesis multiple interactions
EXP
Melphalan results in increased mutagenesis of PIGA Melphalan results in increased mutagenesis of and results in decreased activity of PIGA protein
CTD
PMID:22923490 PMID:27931811
NCBI chr X:31,786,823...31,799,751
Ensembl chr X:31,786,194...31,799,560
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
ISO
Melphalan results in decreased expression of PIK3R1 mRNA
CTD
PMID:22363485
NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
G
Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
decreases expression
ISO
Melphalan results in decreased expression of PIK3R3 mRNA
CTD
PMID:22363485
NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
G
Plcl2
phospholipase C-like 2
decreases expression
ISO
Melphalan results in decreased expression of PLCL2 mRNA
CTD
PMID:22363485
NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654
G
Plekha2
pleckstrin homology domain containing A2
decreases expression
ISO
Melphalan results in decreased expression of PLEKHA2 mRNA
CTD
PMID:22363485
NCBI chr16:71,725,649...71,784,432
Ensembl chr16:71,738,718...71,787,787
G
Plekha5
pleckstrin homology domain containing A5
decreases expression
ISO
Melphalan results in decreased expression of PLEKHA5 mRNA
CTD
PMID:22363485
NCBI chr 4:174,605,462...174,774,692
Ensembl chr 4:174,605,476...174,774,693
G
Plk3
polo-like kinase 3
increases expression
ISO
Melphalan results in increased expression of PLK3 mRNA
CTD
PMID:22363485
NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
G
Ppif
peptidylprolyl isomerase F
increases expression
ISO
Melphalan results in increased expression of PPIF mRNA
CTD
PMID:22363485
NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
G
Ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
decreases expression
ISO
Melphalan results in decreased expression of PPM1H mRNA
CTD
PMID:22363485
NCBI chr 7:66,845,692...67,116,979
Ensembl chr 7:66,843,865...67,116,980
G
Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
decreases expression
ISO
Melphalan results in decreased expression of PPP2R2B mRNA
CTD
PMID:22363485
NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
G
Ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha
decreases expression
ISO
Melphalan results in decreased expression of PPP2R5A mRNA
CTD
PMID:22363485
NCBI chr13:110,033,550...110,077,946
Ensembl chr13:110,033,550...110,077,946
G
Prune2
prune homolog 2 with BCH domain
decreases expression
ISO
Melphalan results in decreased expression of PRUNE2 mRNA
CTD
PMID:22363485
NCBI chr 1:236,676,963...236,947,527
Ensembl chr 1:236,680,098...236,729,412
G
Psd3
pleckstrin and Sec7 domain containing 3
decreases expression
ISO
Melphalan results in decreased expression of PSD3 mRNA
CTD
PMID:22363485
NCBI chr16:23,212,165...23,789,414
Ensembl chr16:23,447,366...23,781,604
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Melphalan results in increased expression of PTGS2 mRNA
CTD
PMID:22363485
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
G
Ptprg
protein tyrosine phosphatase, receptor type, G
decreases expression
ISO
Melphalan results in decreased expression of PTPRG mRNA
CTD
PMID:22363485
NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607
G
Pxk
PX domain containing serine/threonine kinase
decreases expression
ISO
Melphalan results in decreased expression of PXK mRNA
CTD
PMID:22363485
NCBI chr15:18,548,209...18,616,617
Ensembl chr15:18,548,212...18,616,589
G
Rad54b
RAD54 homolog B
decreases expression
ISO
Melphalan results in decreased expression of RAD54B mRNA
CTD
PMID:22363485
NCBI chr 5:25,140,531...25,214,469
Ensembl chr 5:25,146,949...25,214,376
G
Radx
RPA1 related single stranded DNA binding protein, X-linked
decreases expression
ISO
Melphalan results in decreased expression of RADX mRNA
CTD
PMID:22363485
NCBI chr X:110,670,037...110,782,420
Ensembl chr X:110,670,119...110,782,284
G
Rarb
retinoic acid receptor, beta
decreases expression
ISO
Melphalan results in decreased expression of RARB mRNA
CTD
PMID:22363485
NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
G
Rasd1
ras related dexamethasone induced 1
increases expression
ISO
Melphalan results in increased expression of RASD1 mRNA
CTD
PMID:22363485
NCBI chr10:46,330,361...46,339,326
Ensembl chr10:46,330,368...46,332,172
G
Rasl10a
RAS-like, family 10, member A
increases expression
ISO
Melphalan results in increased expression of RASL10A mRNA
CTD
PMID:22363485
NCBI chr14:85,311,833...85,313,211
Ensembl chr14:85,311,089...85,314,270
G
Rasl11b
RAS-like family 11 member B
increases expression
ISO
Melphalan results in increased expression of RASL11B mRNA
CTD
PMID:22363485
NCBI chr14:36,550,353...36,554,574
Ensembl chr14:36,550,340...36,554,580
G
Rbm24
RNA binding motif protein 24
increases expression
ISO
Melphalan results in increased expression of RBM24 mRNA
CTD
PMID:22363485
NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876
G
Rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit
decreases expression
ISO
Melphalan results in decreased expression of REV3L mRNA
CTD
PMID:22363485
NCBI chr20:44,803,664...44,961,362
Ensembl chr20:44,803,666...44,961,382
G
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
decreases expression
ISO
Melphalan results in decreased expression of RGL1 mRNA
CTD
PMID:22363485
NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565
G
Rgmb
repulsive guidance molecule BMP co-receptor b
decreases expression
ISO
Melphalan results in decreased expression of RGMB mRNA
CTD
PMID:22363485
NCBI chr 1:57,794,046...57,819,941
Ensembl chr 1:57,796,709...57,815,038
G
Rgs16
regulator of G-protein signaling 16
increases expression
ISO
Melphalan results in increased expression of RGS16 mRNA
CTD
PMID:22363485
NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
G
Rgs2
regulator of G-protein signaling 2
increases expression
ISO
Melphalan results in increased expression of RGS2 mRNA
CTD
PMID:22363485
NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
G
Ripor2
RHO family interacting cell polarization regulator 2
decreases expression
ISO
Melphalan results in decreased expression of RIPOR2 mRNA
CTD
PMID:22363485
NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
G
Rnf128
ring finger protein 128
decreases expression
ISO
Melphalan results in decreased expression of RNF128 mRNA
CTD
PMID:22363485
NCBI chr X:110,789,061...110,877,964
Ensembl chr X:110,789,269...110,877,978
G
Rnf144b
ring finger protein 144B
decreases expression
ISO
Melphalan results in decreased expression of RNF144B mRNA
CTD
PMID:22363485
NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777
G
Ror1
receptor tyrosine kinase-like orphan receptor 1
decreases expression
ISO
Melphalan results in decreased expression of ROR1 mRNA
CTD
PMID:22363485
NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
G
Rpl27a
ribosomal protein L27a
increases expression
ISO
Melphalan results in increased expression of RPL27A mRNA
CTD
PMID:22363485
NCBI chr 1:174,132,798...174,135,816
Ensembl chr 1:174,132,798...174,135,816
G
Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
increases expression
ISO
Melphalan results in increased expression of RRAD mRNA
CTD
PMID:22363485
NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
G
Rspo2
R-spondin 2
decreases expression
ISO
Melphalan results in decreased expression of RSPO2 mRNA
CTD
PMID:22363485
NCBI chr 7:81,919,911...82,059,659
Ensembl chr 7:81,924,050...82,059,789
G
Runx1t1
RUNX1 partner transcriptional co-repressor 1
decreases expression
ISO
Melphalan results in decreased expression of RUNX1T1 mRNA
CTD
PMID:22363485
NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841
G
Scn8a
sodium voltage-gated channel alpha subunit 8
decreases expression
ISO
Melphalan results in decreased expression of SCN8A mRNA
CTD
PMID:22363485
NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
G
Sema6d
semaphorin 6D
decreases expression
ISO
Melphalan results in decreased expression of SEMA6D mRNA
CTD
PMID:22363485
NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050
G
Serpinb2
serpin family B member 2
increases expression
ISO
Melphalan results in increased expression of SERPINB2 mRNA
CTD
PMID:22363485
NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
G
Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
ISO
Melphalan results in increased expression of SGK1 mRNA
CTD
PMID:22363485
NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
G
Sgms1
sphingomyelin synthase 1
decreases expression
ISO
Melphalan results in decreased expression of SGMS1 mRNA
CTD
PMID:22363485
NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
G
Shank2
SH3 and multiple ankyrin repeat domains 2
decreases expression
ISO
Melphalan results in decreased expression of SHANK2 mRNA
CTD
PMID:22363485
NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
G
Shroom3
shroom family member 3
decreases expression
ISO
Melphalan results in decreased expression of SHROOM3 mRNA
CTD
PMID:22363485
NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242
G
Sik1
salt-inducible kinase 1
increases expression
ISO
Melphalan results in increased expression of SIK1 mRNA
CTD
PMID:22363485
NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
G
Slc14a1
solute carrier family 14 member 1 (Kidd blood group)
decreases expression
ISO
Melphalan results in decreased expression of SLC14A1 mRNA
CTD
PMID:22363485
NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139
G
Slc19a2
solute carrier family 19 member 2
increases expression
ISO
Melphalan results in increased expression of SLC19A2 mRNA
CTD
PMID:22363485
NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
G
Smad2
SMAD family member 2
multiple interactions increases phosphorylation
ISO
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Melphalan results in increased phosphorylation of SMAD2 protein]
CTD
PMID:22363485
NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
G
Smad3
SMAD family member 3
decreases expression
ISO
Melphalan results in decreased expression of SMAD3 mRNA
CTD
PMID:22363485
NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
G
Sntb1
syntrophin, beta 1
decreases expression
ISO
Melphalan results in decreased expression of SNTB1 mRNA
CTD
PMID:22363485
NCBI chr 7:95,395,417...95,670,093
Ensembl chr 7:95,397,113...95,669,809
G
Snx29
sorting nexin 29
decreases expression
ISO
Melphalan results in decreased expression of SNX29 mRNA
CTD
PMID:22363485
NCBI chr10:3,838,444...4,249,741
Ensembl chr10:3,840,622...4,249,739
G
Socs5
suppressor of cytokine signaling 5
decreases expression
ISO
Melphalan results in decreased expression of SOCS5 mRNA
CTD
PMID:22363485
NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
G
Spata17
spermatogenesis associated 17
decreases expression
ISO
Melphalan results in decreased expression of SPATA17 mRNA
CTD
PMID:22363485
NCBI chr13:105,489,121...105,684,293
Ensembl chr13:105,489,074...105,684,374
G
Spata7
spermatogenesis associated 7
decreases expression
ISO
Melphalan results in decreased expression of SPATA7 mRNA
CTD
PMID:22363485
NCBI chr 6:122,603,248...122,648,718
Ensembl chr 6:122,603,269...122,648,699
G
Spred1
sprouty-related, EVH1 domain containing 1
decreases expression
ISO
Melphalan results in decreased expression of SPRED1 mRNA
CTD
PMID:22363485
NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556
G
Spty2d1
SPT2 chromatin protein domain containing 1
increases expression
ISO
Melphalan results in increased expression of SPTY2D1 mRNA
CTD
PMID:22363485
NCBI chr 1:103,115,280...103,129,438
Ensembl chr 1:103,115,216...103,128,743
G
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
decreases expression
ISO
Melphalan results in decreased expression of SRGAP2 mRNA
CTD
PMID:22363485
NCBI chr13:48,065,280...48,286,888
Ensembl chr13:48,068,158...48,286,720
G
Stac
SH3 and cysteine rich domain
decreases expression
ISO
Melphalan results in decreased expression of STAC mRNA
CTD
PMID:22363485
NCBI chr 8:119,820,664...119,941,867
Ensembl chr 8:119,821,901...119,889,661
G
Stambpl1
STAM binding protein-like 1
decreases expression
ISO
Melphalan results in decreased expression of STAMBPL1 mRNA
CTD
PMID:22363485
NCBI chr 1:252,490,125...252,536,113
Ensembl chr 1:252,497,452...252,536,104
G
Tacc2
transforming, acidic coiled-coil containing protein 2
decreases expression
ISO
Melphalan results in decreased expression of TACC2 mRNA
CTD
PMID:22363485
NCBI chr 1:201,140,264...201,329,612
Ensembl chr 1:201,055,644...201,329,622
G
Tbc1d12
TBC1 domain family, member 12
decreases expression
ISO
Melphalan results in decreased expression of TBC1D12 mRNA
CTD
PMID:22363485
NCBI chr 1:257,517,128...257,599,659
Ensembl chr 1:257,517,242...257,883,971
G
Tbl1xr1
TBL1X receptor 1
decreases expression
ISO
Melphalan results in decreased expression of TBL1XR1 mRNA
CTD
PMID:22363485
NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229
G
Tet1
tet methylcytosine dioxygenase 1
decreases expression
ISO
Melphalan results in decreased expression of TET1 mRNA
CTD
PMID:22363485
NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
G
Tex30
testis expressed 30
increases expression
ISO
Melphalan results in increased expression of TEX30 mRNA
CTD
PMID:22363485
NCBI chr 9:50,858,737...50,868,238
Ensembl chr 9:50,858,737...50,868,238
G
Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Melphalan results in increased expression of TFPI2 mRNA
CTD
PMID:22363485
NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]
CTD
PMID:9509296
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
G
Thsd4
thrombospondin type 1 domain containing 4
decreases expression
ISO
Melphalan results in decreased expression of THSD4 mRNA
CTD
PMID:22363485
NCBI chr 8:64,811,940...65,413,498
Ensembl chr 8:64,817,191...65,003,296
G
Tigd2
tigger transposable element derived 2
decreases expression
ISO
Melphalan results in decreased expression of TIGD2 mRNA
CTD
PMID:22363485
NCBI chr 4:89,535,418...89,538,535
Ensembl chr 4:89,536,647...89,538,227
G
Tlnrd1
talin rod domain containing 1
increases expression
ISO
Melphalan results in increased expression of TLNRD1 mRNA
CTD
PMID:22363485
NCBI chr 1:146,027,821...146,029,840
Ensembl chr 1:146,027,822...146,029,840
G
Tlr4
toll-like receptor 4
decreases expression
ISO
Melphalan results in decreased expression of TLR4 mRNA
CTD
PMID:22363485
NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
G
Tmem131l
transmembrane 131 like
decreases expression
ISO
Melphalan results in decreased expression of TMEM131L mRNA
CTD
PMID:22363485
NCBI chr 2:182,897,332...183,031,273
Ensembl chr 2:182,897,830...183,031,214
G
Tmem200a
transmembrane protein 200A
decreases expression
ISO
Melphalan results in decreased expression of TMEM200A mRNA
CTD
PMID:22363485
NCBI chr 1:20,330,670...20,413,921
Ensembl chr 1:20,331,976...20,412,381
G
Tmem26
transmembrane protein 26
decreases expression
ISO
Melphalan results in decreased expression of TMEM26 mRNA
CTD
PMID:22363485
NCBI chr20:21,640,655...21,689,655
Ensembl chr20:21,642,484...21,689,553
G
Tmem88
transmembrane protein 88
increases expression
ISO
Melphalan results in increased expression of TMEM88 mRNA
CTD
PMID:22363485
NCBI chr10:55,998,530...56,000,225
Ensembl chr10:55,998,530...56,000,225
G
Tnf
tumor necrosis factor
increases expression
ISO
Melphalan results in increased expression of TNF mRNA
CTD
PMID:16025434
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
G
Tnfrsf19
TNF receptor superfamily member 19
decreases expression
ISO
Melphalan results in decreased expression of TNFRSF19 mRNA
CTD
PMID:22363485
NCBI chr15:41,249,820...41,316,203
Ensembl chr15:41,246,308...41,338,284
G
Tnni3
troponin I3, cardiac type
increases expression
ISO
Melphalan results in increased expression of TNNI3 protein
CTD
PMID:18548196
NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
G
Tnrc6b
trinucleotide repeat containing adaptor 6B
decreases expression
ISO
Melphalan results in decreased expression of TNRC6B mRNA
CTD
PMID:22363485
NCBI chr 7:121,930,610...122,147,934
Ensembl chr 7:121,930,615...122,147,934
G
Tox
thymocyte selection-associated high mobility group box
decreases expression
ISO
Melphalan results in decreased expression of TOX mRNA
CTD
PMID:22363485
NCBI chr 5:19,892,698...20,189,721
Ensembl chr 5:19,892,698...20,189,721
G
Tp63
tumor protein p63
decreases expression
ISO
Melphalan results in decreased expression of TP63 mRNA
CTD
PMID:22363485
NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
G
Trerf1
transcriptional regulating factor 1
decreases expression
ISO
Melphalan results in decreased expression of TRERF1 mRNA
CTD
PMID:22363485
NCBI chr 9:15,653,230...15,881,695
Ensembl chr 9:15,655,735...15,700,312
G
Trib1
tribbles pseudokinase 1
increases expression
ISO
Melphalan results in increased expression of TRIB1 mRNA
CTD
PMID:22363485
NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
G
Trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
increases expression
ISO
Melphalan results in increased expression of TRMT10C mRNA
CTD
PMID:22363485
NCBI chr11:47,047,342...47,052,420
Ensembl chr11:47,047,342...47,052,418
G
Ttc30b
tetratricopeptide repeat domain 30B
decreases expression
ISO
Melphalan results in decreased expression of TTC30B mRNA
CTD
PMID:22363485
NCBI chr 3:62,758,754...62,761,325
Ensembl chr 3:62,758,758...62,761,325
G
Tubg1
tubulin, gamma 1
increases expression
ISO
Melphalan results in increased expression of TUBG1 protein
CTD
PMID:22025197
NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455
G
Tuft1
tuftelin 1
increases expression
ISO
Melphalan results in increased expression of TUFT1 mRNA
CTD
PMID:22363485
NCBI chr 2:195,861,772...195,907,471
Ensembl chr 2:195,861,649...195,908,037
G
Twnk
twinkle mtDNA helicase
increases expression
ISO
Melphalan results in increased expression of TWNK mRNA
CTD
PMID:22363485
NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
G
Txnrd1
thioredoxin reductase 1
decreases activity
EXP
Melphalan results in decreased activity of TXNRD1 protein
CTD
PMID:16085187
NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
G
Ubap1l
ubiquitin associated protein 1-like
increases expression
ISO
Melphalan results in increased expression of UBAP1L mRNA
CTD
PMID:22363485
NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501
G
Usp36
ubiquitin specific peptidase 36
increases expression
ISO
Melphalan results in increased expression of USP36 mRNA
CTD
PMID:22363485
NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
G
Usp53
ubiquitin specific peptidase 53
decreases expression
ISO
Melphalan results in decreased expression of USP53 mRNA
CTD
PMID:22363485
NCBI chr 2:227,098,795...227,160,385
Ensembl chr 2:227,098,795...227,160,379
G
Utp25
UTP25, small subunit processor component
increases expression
ISO
Melphalan results in increased expression of UTP25 mRNA
CTD
PMID:22363485
NCBI chr13:111,828,052...111,849,654
Ensembl chr13:111,828,043...111,849,653
G
Vdac1
voltage-dependent anion channel 1
multiple interactions
ISO
[arsenic trioxide results in increased expression of VDAC1 protein] which results in increased susceptibility to Melphalan
CTD
PMID:22285227
NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
G
Yod1
YOD1 deubiquitinase
increases expression
ISO
Melphalan results in increased expression of YOD1 mRNA
CTD
PMID:22363485
NCBI chr13:47,441,296...47,443,013
Ensembl chr13:47,440,803...47,443,188
G
Ypel2
yippee-like 2
decreases expression
ISO
Melphalan results in decreased expression of YPEL2 mRNA
CTD
PMID:22363485
NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599
G
Yrdc
yrdC N(6)-threonylcarbamoyltransferase domain containing
increases expression
ISO
Melphalan results in increased expression of YRDC mRNA
CTD
PMID:22363485
NCBI chr 5:142,845,265...142,850,110
Ensembl chr 5:142,845,114...142,850,111
G
Zbtb20
zinc finger and BTB domain containing 20
decreases expression
ISO
Melphalan results in decreased expression of ZBTB20 mRNA
CTD
PMID:22363485
NCBI chr11:62,014,925...62,561,113
Ensembl chr11:62,014,925...62,451,184
G
Zc3h12a
zinc finger CCCH type containing 12A
increases expression
ISO
Melphalan results in increased expression of ZC3H12A mRNA
CTD
PMID:22363485
NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
G
Zfhx4
zinc finger homeobox 4
decreases expression
ISO
Melphalan results in decreased expression of ZFHX4 mRNA
CTD
PMID:22363485
NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368
G
Zfp277
zinc finger protein 277
decreases expression
ISO
Melphalan results in decreased expression of ZNF277 mRNA
CTD
PMID:22363485
NCBI chr 6:60,246,209...60,374,388
Ensembl chr 6:60,246,214...60,374,389
G
Zfp438
zinc finger protein 438
decreases expression
ISO
Melphalan results in decreased expression of ZNF438 mRNA
CTD
PMID:22363485
NCBI chr17:55,006,893...55,131,567
Ensembl chr17:55,008,265...55,129,555
G
Zfp521
zinc finger protein 521
decreases expression
ISO
Melphalan results in decreased expression of ZNF521 mRNA
CTD
PMID:22363485
NCBI chr18:5,022,042...5,315,242
Ensembl chr18:5,032,029...5,314,585
G
Zfp618
zinc finger protein 618
decreases expression
ISO
Melphalan results in decreased expression of ZNF618 mRNA
CTD
PMID:22363485
NCBI chr 5:78,806,585...78,972,433
Ensembl chr 5:78,806,607...78,966,813
G
Zswim5
zinc finger, SWIM-type containing 5
decreases expression
ISO
Melphalan results in decreased expression of ZSWIM5 mRNA
CTD
PMID:22363485
NCBI chr 5:135,735,825...135,854,525
Ensembl chr 5:135,735,825...135,852,575
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all