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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:melphalan
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Accession:CHEBI:28876 term browser browse the term
Definition:A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Synonyms:related_synonym: 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine;   4-(Bis(2-chloroethyl)amino)-L-phenylalanine;   Formula=C13H18Cl2N2O2;   InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1;   InChIKey=SGDBTWWWUNNDEQ-LBPRGKRZSA-N;   L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine;   L-PAM;   L-Phenylalanine mustard;   L-Sarcolysine;   Phenylalanine mustard;   Phenylalanine nitrogen mustard;   SMILES=N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O;   melfalano;   melphalanum;   p-Bis(beta-chloroethyl)aminophenylalanine;   p-Di-(2-chloroethyl)amino-L-phenylalanine;   p-L-Sarcolysin;   p-N,N-bis(2-chloroethyl)amino-L-phenylalanine;   p-N-Bis(2-chloroethyl)amino-L-phenylalanine
 alt_id: CHEBI:25815;   CHEBI:6742
 xref: CAS:148-82-3;   DrugBank:DB01042;   Drug_Central:1678;   KEGG:D00369
 xref_mesh: MESH:D008558
 xref: PMID:10820424;   PMID:10937717;   PMID:11680815;   PMID:11914777;   PMID:18481314;   PMID:445303;   PMID:7494795;   PMID:7605343;   PMID:8552138;   PMID:8951232;   PMID:9218926;   PMID:9250538;   Patent:US108552;   Patent:US275057;   Patent:US3032584;   Patent:US3032585;   Reaxys:2816456;   Wikipedia:Melphalan


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melphalan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export ISO ABCC1 protein affects the export of Melphalan analog CTD PMID:11115505 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO Melphalan results in decreased expression of ABHD17C mRNA CTD PMID:22363485 NCBI chr 1:138,084,632...138,125,595
Ensembl chr 1:138,084,634...138,125,595 		JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit decreases expression ISO Melphalan results in decreased expression of ABRAXAS1 mRNA CTD PMID:22363485 NCBI chr14:8,796,281...8,810,625
Ensembl chr14:8,796,266...8,810,622 		JBrowse link
G Abt1 activator of basal transcription 1 increases expression ISO Melphalan results in increased expression of ABT1 mRNA CTD PMID:22363485 NCBI chr17:41,699,151...41,701,253
Ensembl chr17:41,699,147...41,701,259 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Melphalan results in increased expression of ACKR3 mRNA CTD PMID:22363485 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Melphalan results in decreased expression of ACVR1C mRNA CTD PMID:22363485 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO Melphalan results in decreased expression of AHRR mRNA CTD PMID:22363485 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Alad aminolevulinate dehydratase decreases activity ISO Melphalan results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Ammecr1l AMMECR1 like increases expression ISO Melphalan results in increased expression of AMMECR1L mRNA CTD PMID:22363485 NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,386,903...23,410,920 		JBrowse link
G Ankar ankyrin and armadillo repeat containing decreases expression ISO Melphalan results in decreased expression of ANKAR mRNA CTD PMID:22363485 NCBI chr 9:48,141,534...48,215,400
Ensembl chr 9:48,141,391...48,215,616 		JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Melphalan results in increased expression of ANKRD10 mRNA CTD PMID:22363485 NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745 		JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression ISO Melphalan results in decreased expression of ANKRD28 mRNA CTD PMID:22363485 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Melphalan results in decreased expression of ANKRD34A mRNA CTD PMID:22363485 NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116 		JBrowse link
G Ar androgen receptor decreases expression ISO Melphalan results in decreased expression of AR mRNA CTD PMID:22363485 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgap12 Rho GTPase activating protein 12 decreases expression ISO Melphalan results in decreased expression of ARHGAP12 mRNA CTD PMID:22363485 NCBI chr17:51,588,810...51,702,417
Ensembl chr17:51,588,842...51,702,080 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Melphalan results in decreased expression of ARHGAP18 mRNA CTD PMID:22363485 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256 		JBrowse link
G Arhgap20 Rho GTPase activating protein 20 decreases expression ISO Melphalan results in decreased expression of ARHGAP20 mRNA CTD PMID:22363485 NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO Melphalan results in decreased expression of ARHGAP24 mRNA CTD PMID:22363485 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO Melphalan results in decreased expression of ARHGAP42 mRNA CTD PMID:22363485 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Melphalan results in increased expression of ARID5A mRNA CTD PMID:22363485 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression ISO Melphalan results in increased expression of ATG16L1 mRNA CTD PMID:22363485 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Melphalan results in decreased expression of ATP2B1 mRNA CTD PMID:22363485 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Aurka aurora kinase A increases expression ISO Melphalan results in increased expression of AURKA protein CTD PMID:22025197 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Melphalan results in decreased expression of AURKB protein CTD PMID:22025197 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 increases expression ISO Melphalan results in increased expression of B3GNT2 mRNA CTD PMID:22363485 NCBI chr14:96,808,473...96,833,674
Ensembl chr14:96,806,664...96,835,273 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Melphalan results in increased expression of B3GNT5 mRNA CTD PMID:22363485 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Melphalan results in increased expression of BAK1 protein CTD PMID:22285227 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Melphalan results in increased expression of and results in decreased localization of BAX protein CTD PMID:22285227 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein CTD PMID:4672170 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Melphalan results in decreased expression of BCL2 protein CTD PMID:22285227 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Melphalan results in increased expression of BCL2A1 mRNA CTD PMID:22363485 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO Melphalan results in decreased expression of BICC1 mRNA CTD PMID:22363485 NCBI chr20:17,449,644...17,686,775
Ensembl chr20:17,449,560...17,686,776 		JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 increases expression ISO Melphalan results in increased expression of BICDL2 mRNA CTD PMID:22363485 NCBI chr10:12,691,610...12,700,049
Ensembl chr10:12,691,610...12,700,049 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects response to substance
decreases expression
multiple interactions		 ISO BIRC5 protein affects the susceptibility to Melphalan
Melphalan results in decreased expression of BIRC5 protein
Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]; Paclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]		 CTD PMID:16373717 PMID:22025197 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO Melphalan results in decreased expression of BNC2 mRNA CTD PMID:22363485 NCBI chr 5:98,679,071...99,079,742
Ensembl chr 5:98,687,410...99,079,426 		JBrowse link
G Btbd8 BTB domain containing 8 decreases expression ISO Melphalan results in decreased expression of BTBD8 mRNA CTD PMID:22363485 NCBI chr14:2,265,189...2,338,426
Ensembl chr14:2,266,454...2,334,393 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Melphalan results in increased expression of BTG2 mRNA CTD PMID:22363485 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression ISO Melphalan results in decreased expression of CABLES1 mRNA CTD PMID:22363485 NCBI chr18:3,076,556...3,181,183
Ensembl chr18:3,075,524...3,181,181 		JBrowse link
G Casp3 caspase 3 increases activity ISO Melphalan results in increased activity of CASP3 protein CTD PMID:16951922 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Melphalan results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:22285227 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity ISO Melphalan results in decreased activity of CAT protein CTD PMID:19162187 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Melphalan results in decreased expression of CC2D2A mRNA CTD PMID:22363485 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949 		JBrowse link
G Ccdc110 coiled-coil domain containing 110 decreases expression ISO Melphalan results in decreased expression of CCDC110 mRNA CTD PMID:22363485 NCBI chr16:46,315,745...46,337,050
Ensembl chr16:46,315,745...46,337,021 		JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO Melphalan results in decreased expression of CCDC171 mRNA CTD PMID:22363485 NCBI chr 5:97,919,965...98,403,853
Ensembl chr 5:97,920,002...98,282,833 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Melphalan results in increased expression of CCL20 mRNA CTD PMID:22363485 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccnj cyclin J increases expression ISO Melphalan results in increased expression of CCNJ mRNA CTD PMID:22363485 NCBI chr 1:239,659,588...239,677,367 JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein CTD PMID:10618687 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd59b CD59b molecule decreases lipidation EXP Melphalan results in decreased lipidation of CD59 protein CTD PMID:27931811 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cda cytidine deaminase decreases response to substance ISO CDA protein results in decreased susceptibility to Melphalan CTD PMID:10830723 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Melphalan results in decreased expression of CDC14B mRNA CTD PMID:22363485 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Melphalan results in decreased expression of CDC42EP3 mRNA CTD PMID:22363485 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721 		JBrowse link
G Cfap206 cilia and flagella associated protein 206 decreases expression ISO Melphalan results in decreased expression of CFAP206 mRNA CTD PMID:22363485 NCBI chr 5:49,254,399...49,299,145
Ensembl chr 5:49,254,408...49,299,090 		JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK1 protein CTD PMID:26208482 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK2 protein CTD PMID:26208482 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex affects phosphorylation ISO Melphalan affects the phosphorylation of CHUK protein CTD PMID:19934314 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Melphalan results in decreased expression of CIITA mRNA CTD PMID:22363485 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 increases expression ISO Melphalan results in increased expression of CITED4 mRNA CTD PMID:22363485 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135 		JBrowse link
G Cnksr3 Cnksr family member 3 decreases expression ISO Melphalan results in decreased expression of CNKSR3 mRNA CTD PMID:22363485 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635 		JBrowse link
G Cpne8 copine 8 decreases expression ISO Melphalan results in decreased expression of CPNE8 mRNA CTD PMID:22363485 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO Melphalan results in decreased expression of CREB5 mRNA CTD PMID:22363485 NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325 		JBrowse link
G Cul3 cullin 3 increases expression ISO Melphalan results in increased expression of CUL3 mRNA CTD PMID:22363485 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Melphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP		 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP		 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Melphalan results in increased expression of CYP27B1 mRNA CTD PMID:22363485 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyria CYFIP related Rac1 interactor A decreases expression ISO Melphalan results in decreased expression of CYRIA mRNA CTD PMID:22363485 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668 		JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO Melphalan results in increased expression of DBF4 mRNA CTD PMID:22363485 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dennd4c DENN domain containing 4C decreases expression ISO Melphalan results in decreased expression of DENND4C mRNA CTD PMID:22363485 NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 decreases expression ISO Melphalan results in decreased expression of DLG3 mRNA CTD PMID:22363485 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322 		JBrowse link
G Dst dystonin decreases expression ISO Melphalan results in decreased expression of DST mRNA CTD PMID:22363485 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Melphalan results in increased expression of DUSP2 mRNA CTD PMID:22363485 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Eaf1 ELL associated factor 1 increases expression ISO Melphalan results in increased expression of EAF1 mRNA CTD PMID:22363485 NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071 		JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Melphalan results in decreased expression of EBF1 mRNA CTD PMID:22363485 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Melphalan results in increased expression of EDN1 protein CTD PMID:18548196 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 decreases expression ISO Melphalan results in decreased expression of EEPD1 mRNA CTD PMID:22363485 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340 		JBrowse link
G Efna2 ephrin A2 increases expression ISO Melphalan results in increased expression of EFNA2 mRNA CTD PMID:22363485 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061 		JBrowse link
G Efna5 ephrin A5 decreases expression ISO Melphalan results in decreased expression of EFNA5 mRNA CTD PMID:22363485 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Melphalan results in decreased expression of EMX2 mRNA CTD PMID:22363485 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO Melphalan results in decreased expression of ENOX1 mRNA CTD PMID:22363485 NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749 		JBrowse link
G Epha5 EPH receptor A5 decreases expression ISO Melphalan results in decreased expression of EPHA5 mRNA CTD PMID:22363485 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317 		JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO Melphalan results in decreased expression of EXOC6 mRNA CTD PMID:22363485 NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Melphalan results in increased expression of FABP5 mRNA CTD PMID:22363485 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression ISO Melphalan results in decreased expression of FAM110B mRNA CTD PMID:22363485 NCBI chr 5:18,789,362...18,929,647
Ensembl chr 5:18,789,389...18,929,828 		JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 decreases expression ISO Melphalan results in decreased expression of FAM90A1 mRNA CTD PMID:22363485 NCBI chr16:70,098,439...70,106,147
Ensembl chr16:70,098,740...70,101,241 		JBrowse link
G Fancc FA complementation group C increases response to substance ISO FANCC protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376 		JBrowse link
G Fancg FA complementation group G increases response to substance ISO FANCG protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO Melphalan results in decreased expression of FAT4 mRNA CTD PMID:22363485 NCBI chr 2:121,928,188...122,056,711
Ensembl chr 2:121,927,942...122,056,707 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 decreases expression ISO Melphalan results in decreased expression of FGD4 mRNA CTD PMID:22363485 NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 decreases expression ISO Melphalan results in decreased expression of FGD6 mRNA CTD PMID:22363485 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Melphalan results in decreased expression of FGF5 mRNA CTD PMID:22363485 NCBI chr14:11,325,334...11,346,570
Ensembl chr14:11,325,334...11,345,997 		JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Melphalan results in decreased expression of FIGN mRNA CTD PMID:22363485 NCBI chr 3:48,637,510...48,760,772
Ensembl chr 3:48,642,496...48,760,787 		JBrowse link
G Fmn2 formin 2 decreases expression ISO Melphalan results in decreased expression of FMN2 mRNA CTD PMID:22363485 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Melphalan results in increased expression of FOSB mRNA CTD PMID:22363485 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO Melphalan results in decreased expression of FOXP2 mRNA CTD PMID:22363485 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Frmd4a FERM domain containing 4A decreases expression ISO Melphalan results in decreased expression of FRMD4A mRNA CTD PMID:22363485 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687 		JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO Melphalan results in decreased expression of FRMD4B mRNA CTD PMID:22363485 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197 		JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Melphalan results in decreased expression of FRY mRNA CTD PMID:22363485 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fut10 fucosyltransferase 10 decreases expression ISO Melphalan results in decreased expression of FUT10 mRNA CTD PMID:22363485 NCBI chr16:60,868,761...60,958,762
Ensembl chr16:60,877,952...60,958,683 		JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression ISO Melphalan results in decreased expression of GAB1 mRNA CTD PMID:22363485 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 decreases expression ISO Melphalan results in decreased expression of GAREM1 mRNA CTD PMID:22363485 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO Melphalan results in decreased expression of GAS1 mRNA CTD PMID:22363485 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 decreases expression ISO Melphalan results in decreased expression of GCNT1 mRNA CTD PMID:22363485 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776 		JBrowse link
G Glb1 galactosidase, beta 1 increases expression ISO Melphalan results in increased expression of GLB1 protein CTD PMID:33491125 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO Melphalan results in decreased expression of GLI3 mRNA CTD PMID:22363485 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO Melphalan results in increased expression of GRIN2C mRNA CTD PMID:22363485 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 decreases expression ISO Melphalan results in decreased expression of GRK5 mRNA CTD PMID:22363485 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Melphalan CTD PMID:8860835 PMID:10215608 PMID:10830723 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases response to substance EXP GSTA5 protein results in decreased susceptibility to Melphalan CTD PMID:12076520 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases response to substance ISO GSTM1 protein results in decreased susceptibility to Melphalan CTD PMID:20067466 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]; Melphalan inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:12791655 PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO Melphalan results in decreased expression of HECW2 mRNA CTD PMID:22363485 NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO Melphalan results in decreased expression of HGF mRNA CTD PMID:22363485 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Melphalan results in decreased expression of HMGA2 mRNA CTD PMID:22363485 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Melphalan results in increased expression of HOXD1 mRNA CTD PMID:22363485 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Melphalan results in increased expression of ICAM1 protein CTD PMID:16025434 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO Melphalan results in increased expression of IER3 mRNA CTD PMID:22363485 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ift70b intraflagellar transport 70B decreases expression ISO Melphalan results in decreased expression of IFT70B mRNA CTD PMID:22363485 NCBI chr 3:60,855,809...60,858,380
Ensembl chr 3:60,855,575...60,858,389 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO Melphalan results in decreased expression of IKBKE mRNA CTD PMID:22363485 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Melphalan results in decreased expression of IKZF2 mRNA CTD PMID:22363485 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Il12a interleukin 12A increases expression ISO Melphalan results in increased expression of IL12A mRNA CTD PMID:22363485 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il16 interleukin 16 decreases expression ISO Melphalan results in decreased expression of IL16 mRNA CTD PMID:22363485 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO Melphalan results in increased expression of and results in increased secretion of IL1B protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]
Melphalan results in increased expression of IL1B mRNA		 CTD PMID:21129433 PMID:22363485 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions		 ISO Melphalan results in increased expression of IL23A protein
TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]		 CTD PMID:21129433 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Melphalan results in increased expression of and results in increased secretion of IL6 protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein] CTD PMID:21129433 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7 interleukin 7 decreases expression ISO Melphalan results in decreased expression of IL7 mRNA CTD PMID:22363485 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Melphalan results in decreased expression of IRF2 mRNA CTD PMID:22363485 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024 		JBrowse link
G Jade2 jade family PHD finger 2 decreases expression ISO Melphalan results in decreased expression of JADE2 mRNA CTD PMID:22363485 NCBI chr10:36,076,483...36,124,210
Ensembl chr10:36,078,917...36,116,984 		JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 decreases expression ISO Melphalan results in decreased expression of JAKMIP3 mRNA CTD PMID:22363485 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104 		JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO Melphalan results in decreased expression of KALRN mRNA CTD PMID:22363485 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610 		JBrowse link
G Kbtbd3 kelch repeat and BTB domain containing 3 decreases expression ISO Melphalan results in decreased expression of KBTBD3 mRNA CTD PMID:22363485 NCBI chr 8:1,464,162...1,491,144
Ensembl chr 8:1,473,247...1,487,943 		JBrowse link
G Kitlg KIT ligand decreases expression ISO Melphalan results in decreased expression of KITLG mRNA CTD PMID:22363485 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klf12 KLF transcription factor 12 decreases expression ISO Melphalan results in decreased expression of KLF12 mRNA CTD PMID:22363485 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056 		JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Melphalan results in increased expression of KLHL42 mRNA CTD PMID:22363485 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283 		JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO Melphalan results in decreased expression of LRIG3 mRNA CTD PMID:22363485 NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481 		JBrowse link
G Lurap1 leucine rich adaptor protein 1 decreases expression ISO Melphalan results in decreased expression of LURAP1 mRNA CTD PMID:22363485 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766 		JBrowse link
G Lyst lysosomal trafficking regulator decreases expression ISO Melphalan results in decreased expression of LYST mRNA CTD PMID:22363485 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:16025434 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16025434 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Melphalan results in decreased expression of MBOAT1 mRNA CTD PMID:22363485 NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088 		JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression ISO Melphalan results in decreased expression of MEOX2 mRNA CTD PMID:22363485 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467 		JBrowse link
G Mex3a mex-3 RNA binding family member A increases expression ISO Melphalan results in increased expression of MEX3A mRNA CTD PMID:22363485 NCBI chr 2:173,989,491...173,999,567
Ensembl chr 2:173,989,856...173,997,377 		JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO Melphalan results in increased expression of MEX3B mRNA CTD PMID:22363485 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid increases expression ISO Melphalan results in increased expression of MFSD2A mRNA CTD PMID:22363485 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases response to substance ISO MGST2 protein results in decreased susceptibility to Melphalan CTD PMID:15779864 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Melphalan results in decreased expression of MITF mRNA CTD PMID:22363485 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit decreases expression ISO Melphalan results in decreased expression of MLLT3 mRNA CTD PMID:22363485 NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361 		JBrowse link
G Mms22l MMS22-like, DNA repair protein decreases expression ISO Melphalan results in decreased expression of MMS22L mRNA CTD PMID:22363485 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745 		JBrowse link
G Mrtfb myocardin related transcription factor B decreases expression ISO Melphalan results in decreased expression of MRTFB mRNA CTD PMID:22363485 NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897 		JBrowse link
G Mta3 metastasis associated 1 family, member 3 decreases expression ISO Melphalan results in decreased expression of MTA3 mRNA CTD PMID:22363485 NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883 		JBrowse link
G Mtcl1 microtubule crosslinking factor 1 decreases expression ISO Melphalan results in decreased expression of MTCL1 mRNA CTD PMID:22363485 NCBI chr 9:106,305,282...106,441,782
Ensembl chr 9:106,321,098...106,442,203 		JBrowse link
G Myo1b myosin Ib decreases expression ISO Melphalan results in decreased expression of MYO1B mRNA CTD PMID:22363485 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Nebl nebulette increases expression ISO Melphalan results in increased expression of NEBL mRNA CTD PMID:22363485 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210 		JBrowse link
G Nfia nuclear factor I/A decreases expression ISO Melphalan results in decreased expression of NFIA mRNA CTD PMID:22363485 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885 		JBrowse link
G Nhs NHS actin remodeling regulator decreases expression ISO Melphalan results in decreased expression of NHS mRNA CTD PMID:22363485 NCBI chr  X:32,551,974...32,892,961
Ensembl chr  X:32,552,026...32,889,992 		JBrowse link
G Nkrf NFKB repressing factor increases expression ISO Melphalan results in increased expression of NKRF mRNA CTD PMID:22363485 NCBI chr  X:116,126,341...116,144,577
Ensembl chr  X:116,128,798...116,144,628 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO Melphalan results in increased expression of NOP56 mRNA CTD PMID:22363485 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841 		JBrowse link
G Nppb natriuretic peptide B increases expression ISO Melphalan results in increased expression of NPPB protein CTD PMID:18548196 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Melphalan results in increased expression of NR4A3 mRNA CTD PMID:22363485 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nrg2 neuregulin 2 decreases expression ISO Melphalan results in decreased expression of NRG2 mRNA CTD PMID:22363485 NCBI chr18:27,619,635...27,798,505
Ensembl chr18:27,619,661...27,798,505 		JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO Melphalan results in decreased expression of NRP1 mRNA CTD PMID:22363485 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Melphalan results in decreased expression of NUAK1 mRNA CTD PMID:22363485 NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 decreases expression ISO Melphalan results in decreased expression of OSBPL10 mRNA CTD PMID:22363485 NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Melphalan results in decreased expression of PAG1 mRNA CTD PMID:22363485 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Melphalan results in decreased expression of PDLIM5 mRNA CTD PMID:22363485 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Phf21a PHD finger protein 21A decreases expression ISO Melphalan results in decreased expression of PHF21A mRNA CTD PMID:22363485 NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865 		JBrowse link
G Phf3 PHD finger protein 3 decreases expression ISO Melphalan results in decreased expression of PHF3 mRNA CTD PMID:22363485 NCBI chr 9:33,063,855...33,136,013
Ensembl chr 9:33,063,857...33,135,994 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Melphalan results in increased expression of PHLDA1 mRNA CTD PMID:22363485 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression ISO Melphalan results in decreased expression of PHLDB2 mRNA CTD PMID:22363485 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis
multiple interactions		 EXP Melphalan results in increased mutagenesis of PIGA
Melphalan results in increased mutagenesis of and results in decreased activity of PIGA protein		 CTD PMID:22923490 PMID:27931811 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Melphalan results in decreased expression of PIK3R1 mRNA CTD PMID:22363485 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO Melphalan results in decreased expression of PIK3R3 mRNA CTD PMID:22363485 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Melphalan results in decreased expression of PLCL2 mRNA CTD PMID:22363485 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO Melphalan results in decreased expression of PLEKHA2 mRNA CTD PMID:22363485 NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395 		JBrowse link
G Plekha5 pleckstrin homology domain containing A5 decreases expression ISO Melphalan results in decreased expression of PLEKHA5 mRNA CTD PMID:22363485 NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546 		JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Melphalan results in increased expression of PLK3 mRNA CTD PMID:22363485 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
G Ppif peptidylprolyl isomerase F increases expression ISO Melphalan results in increased expression of PPIF mRNA CTD PMID:22363485 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H decreases expression ISO Melphalan results in decreased expression of PPM1H mRNA CTD PMID:22363485 NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Melphalan results in decreased expression of PPP2R2B mRNA CTD PMID:22363485 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha decreases expression ISO Melphalan results in decreased expression of PPP2R5A mRNA CTD PMID:22363485 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:102,931,264...102,975,661 		JBrowse link
G Prune2 prune homolog 2 with BCH domain decreases expression ISO Melphalan results in decreased expression of PRUNE2 mRNA CTD PMID:22363485 NCBI chr 1:214,352,586...214,624,848
Ensembl chr 1:214,352,955...214,622,650 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 decreases expression ISO Melphalan results in decreased expression of PSD3 mRNA CTD PMID:22363485 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Melphalan results in increased expression of PTGS2 mRNA CTD PMID:22363485 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Melphalan results in decreased expression of PTPRG mRNA CTD PMID:22363485 NCBI chr15:12,872,284...13,552,186
Ensembl chr15:12,871,721...13,554,094 		JBrowse link
G Pxk PX domain containing serine/threonine kinase decreases expression ISO Melphalan results in decreased expression of PXK mRNA CTD PMID:22363485 NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444 		JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO Melphalan results in decreased expression of RAD54B mRNA CTD PMID:22363485 NCBI chr 5:25,030,885...25,104,616
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked decreases expression ISO Melphalan results in decreased expression of RADX mRNA CTD PMID:22363485 NCBI chr  X:103,089,284...103,176,840
Ensembl chr  X:103,089,284...103,176,838 		JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO Melphalan results in decreased expression of RARB mRNA CTD PMID:22363485 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO Melphalan results in increased expression of RASD1 mRNA CTD PMID:22363485 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186 		JBrowse link
G Rasl10a RAS-like, family 10, member A increases expression ISO Melphalan results in increased expression of RASL10A mRNA CTD PMID:22363485 NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468 		JBrowse link
G Rasl11b RAS-like family 11 member B increases expression ISO Melphalan results in increased expression of RASL11B mRNA CTD PMID:22363485 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152 		JBrowse link
G Rbm24 RNA binding motif protein 24 increases expression ISO Melphalan results in increased expression of RBM24 mRNA CTD PMID:22363485 NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit decreases expression ISO Melphalan results in decreased expression of REV3L mRNA CTD PMID:22363485 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099 		JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator like 1 decreases expression ISO Melphalan results in decreased expression of RGL1 mRNA CTD PMID:22363485 NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b decreases expression ISO Melphalan results in decreased expression of RGMB mRNA CTD PMID:22363485 NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Melphalan results in increased expression of RGS16 mRNA CTD PMID:22363485 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Melphalan results in increased expression of RGS2 mRNA CTD PMID:22363485 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 decreases expression ISO Melphalan results in decreased expression of RIPOR2 mRNA CTD PMID:22363485 NCBI chr17:40,323,867...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Melphalan results in decreased expression of RNF128 mRNA CTD PMID:22363485 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423 		JBrowse link
G Rnf144b ring finger protein 144B decreases expression ISO Melphalan results in decreased expression of RNF144B mRNA CTD PMID:22363485 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO Melphalan results in decreased expression of ROR1 mRNA CTD PMID:22363485 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Rpl27a ribosomal protein L27A increases expression ISO Melphalan results in increased expression of RPL27A mRNA CTD PMID:22363485 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Melphalan results in increased expression of RRAD mRNA CTD PMID:22363485 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Melphalan results in decreased expression of RSPO2 mRNA CTD PMID:22363485 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 decreases expression ISO Melphalan results in decreased expression of RUNX1T1 mRNA CTD PMID:22363485 NCBI chr 5:27,187,674...27,338,070
Ensembl chr 5:27,187,551...27,335,592 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 decreases expression ISO Melphalan results in decreased expression of SCN8A mRNA CTD PMID:22363485 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292 		JBrowse link
G Sema6d semaphorin 6D decreases expression ISO Melphalan results in decreased expression of SEMA6D mRNA CTD PMID:22363485 NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Melphalan results in increased expression of SERPINB2 mRNA CTD PMID:22363485 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Melphalan results in increased expression of SGK1 mRNA CTD PMID:22363485 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO Melphalan results in decreased expression of SGMS1 mRNA CTD PMID:22363485 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 decreases expression ISO Melphalan results in decreased expression of SHANK2 mRNA CTD PMID:22363485 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shroom3 shroom family member 3 decreases expression ISO Melphalan results in decreased expression of SHROOM3 mRNA CTD PMID:22363485 NCBI chr14:15,099,415...15,396,832
Ensembl chr14:15,099,423...15,396,915 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Melphalan results in increased expression of SIK1 mRNA CTD PMID:22363485 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO Melphalan results in decreased expression of SLC14A1 mRNA CTD PMID:22363485 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146 		JBrowse link
G Slc19a2 solute carrier family 19 member 2 increases expression ISO Melphalan results in increased expression of SLC19A2 mRNA CTD PMID:22363485 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation		 ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Melphalan results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO Melphalan results in decreased expression of SMAD3 mRNA CTD PMID:22363485 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Snord22 small nucleolar RNA, C/D box 22 increases expression ISO Melphalan results in increased expression of SNORD22 mRNA CTD PMID:22363485 NCBI chr11:9,097,799...9,097,923
Ensembl chr11:9,097,799...9,097,923 		JBrowse link
G Sntb1 syntrophin, beta 1 decreases expression ISO Melphalan results in decreased expression of SNTB1 mRNA CTD PMID:22363485 NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315 		JBrowse link
G Snx29 sorting nexin 29 decreases expression ISO Melphalan results in decreased expression of SNX29 mRNA CTD PMID:22363485 NCBI chr10:3,884,880...4,298,699
Ensembl chr10:3,888,301...4,298,655 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression ISO Melphalan results in decreased expression of SOCS5 mRNA CTD PMID:22363485 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Spata17 spermatogenesis associated 17 decreases expression ISO Melphalan results in decreased expression of SPATA17 mRNA CTD PMID:22363485 NCBI chr13:98,605,986...98,784,855
Ensembl chr13:98,605,986...98,784,929 		JBrowse link
G Spata7 spermatogenesis associated 7 decreases expression ISO Melphalan results in decreased expression of SPATA7 mRNA CTD PMID:22363485 NCBI chr 6:117,879,828...117,925,284
Ensembl chr 6:117,879,823...117,925,284 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 decreases expression ISO Melphalan results in decreased expression of SPRED1 mRNA CTD PMID:22363485 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 increases expression ISO Melphalan results in increased expression of SPTY2D1 mRNA CTD PMID:22363485 NCBI chr 1:97,531,495...97,549,633
Ensembl chr 1:97,531,508...97,549,581 		JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO Melphalan results in decreased expression of SRGAP2 mRNA CTD PMID:22363485 NCBI chr13:42,745,956...42,967,083
Ensembl chr13:42,745,947...42,967,058 		JBrowse link
G Stac SH3 and cysteine rich domain decreases expression ISO Melphalan results in decreased expression of STAC mRNA CTD PMID:22363485 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008 		JBrowse link
G Stambpl1 STAM binding protein-like 1 decreases expression ISO Melphalan results in decreased expression of STAMBPL1 mRNA CTD PMID:22363485 NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032 		JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO Melphalan results in decreased expression of TACC2 mRNA CTD PMID:22363485 NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881 		JBrowse link
G Tbc1d12 TBC1 domain family, member 12 decreases expression ISO Melphalan results in decreased expression of TBC1D12 mRNA CTD PMID:22363485 NCBI chr 1:236,603,597...236,685,859
Ensembl chr 1:236,603,607...236,685,859 		JBrowse link
G Tbl1xr1 TBL1X/Y related 1 decreases expression ISO Melphalan results in decreased expression of TBL1XR1 mRNA CTD PMID:22363485 NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression ISO Melphalan results in decreased expression of TET1 mRNA CTD PMID:22363485 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tex30 testis expressed 30 increases expression ISO Melphalan results in increased expression of TEX30 mRNA CTD PMID:22363485 NCBI chr 9:46,242,748...46,252,273
Ensembl chr 9:46,242,748...46,252,249 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Melphalan results in increased expression of TFPI2 mRNA CTD PMID:22363485 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa] CTD PMID:9509296 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 decreases expression ISO Melphalan results in decreased expression of THSD4 mRNA CTD PMID:22363485 NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:60,386,875...61,024,995 		JBrowse link
G Tigd2 tigger transposable element derived 2 decreases expression ISO Melphalan results in decreased expression of TIGD2 mRNA CTD PMID:22363485 NCBI chr 4:88,414,366...88,417,458
Ensembl chr 4:88,414,518...88,417,785 		JBrowse link
G Tlnrd1 talin rod domain containing 1 increases expression ISO Melphalan results in increased expression of TLNRD1 mRNA CTD PMID:22363485 NCBI chr 1:137,864,340...137,866,359
Ensembl chr 1:137,864,343...137,866,359 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Melphalan results in decreased expression of TLR4 mRNA CTD PMID:22363485 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmem131l transmembrane 131 like decreases expression ISO Melphalan results in decreased expression of TMEM131L mRNA CTD PMID:22363485 NCBI chr 2:169,257,659...169,391,773
Ensembl chr 2:169,258,289...169,391,711 		JBrowse link
G Tmem200a transmembrane protein 200A decreases expression ISO Melphalan results in decreased expression of TMEM200A mRNA CTD PMID:22363485 NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453 		JBrowse link
G Tmem26 transmembrane protein 26 decreases expression ISO Melphalan results in decreased expression of TMEM26 mRNA CTD PMID:22363485 NCBI chr20:19,820,768...19,872,561
Ensembl chr20:19,822,975...19,872,023 		JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Melphalan results in increased expression of TMEM88 mRNA CTD PMID:22363485 NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Melphalan results in increased expression of TNF mRNA CTD PMID:16025434 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases expression ISO Melphalan results in decreased expression of TNFRSF19 mRNA CTD PMID:22363485 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Melphalan results in increased expression of TNNI3 protein CTD PMID:18548196 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B decreases expression ISO Melphalan results in decreased expression of TNRC6B mRNA CTD PMID:22363485 NCBI chr 7:112,252,351...112,469,829
Ensembl chr 7:112,252,359...112,461,790 		JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression ISO Melphalan results in decreased expression of TOX mRNA CTD PMID:22363485 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Melphalan affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Melphalan results in decreased expression of TP63 mRNA CTD PMID:22363485 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Trerf1 transcriptional regulating factor 1 decreases expression ISO Melphalan results in decreased expression of TRERF1 mRNA CTD PMID:22363485 NCBI chr 9:13,631,619...13,858,326
Ensembl chr 9:13,634,126...13,857,029 		JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Melphalan results in increased expression of TRIB1 mRNA CTD PMID:22363485 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit increases expression ISO Melphalan results in increased expression of TRMT10C mRNA CTD PMID:22363485 NCBI chr11:44,584,388...44,589,466
Ensembl chr11:44,584,113...44,589,568 		JBrowse link
G Tubg1 tubulin, gamma 1 increases expression ISO Melphalan results in increased expression of TUBG1 protein CTD PMID:22025197 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Melphalan results in increased expression of TUFT1 mRNA CTD PMID:22363485 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192 		JBrowse link
G Twnk twinkle mtDNA helicase increases expression ISO Melphalan results in increased expression of TWNK mRNA CTD PMID:22363485 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Melphalan results in decreased activity of TXNRD1 protein CTD PMID:16085187 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ubap1l ubiquitin associated protein 1-like increases expression ISO Melphalan results in increased expression of UBAP1L mRNA CTD PMID:22363485 NCBI chr 8:65,877,488...65,897,593
Ensembl chr 8:65,884,729...65,897,593 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Melphalan results in increased expression of USP36 mRNA CTD PMID:22363485 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877 		JBrowse link
G Usp53 ubiquitin specific peptidase 53 decreases expression ISO Melphalan results in decreased expression of USP53 mRNA CTD PMID:22363485 NCBI chr 2:211,059,512...211,120,942
Ensembl chr 2:211,059,520...211,120,943 		JBrowse link
G Utp25 UTP25 small subunit processome component increases expression ISO Melphalan results in increased expression of UTP25 mRNA CTD PMID:22363485 NCBI chr13:104,630,390...104,651,681
Ensembl chr13:104,630,391...104,651,662 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [arsenic trioxide results in increased expression of VDAC1 protein] which results in increased susceptibility to Melphalan CTD PMID:22285227 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Yod1 YOD1 deubiquitinase increases expression ISO Melphalan results in increased expression of YOD1 mRNA CTD PMID:22363485 NCBI chr13:42,175,313...42,177,030
Ensembl chr13:42,174,820...42,177,205 		JBrowse link
G Ypel2 yippee-like 2 decreases expression ISO Melphalan results in decreased expression of YPEL2 mRNA CTD PMID:22363485 NCBI chr10:71,746,308...71,803,855
Ensembl chr10:71,746,311...71,803,911 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing increases expression ISO Melphalan results in increased expression of YRDC mRNA CTD PMID:22363485 NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression ISO Melphalan results in decreased expression of ZBTB20 mRNA CTD PMID:22363485 NCBI chr11:57,052,129...57,823,679
Ensembl chr11:57,072,880...57,510,210 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Melphalan results in increased expression of ZC3H12A mRNA CTD PMID:22363485 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Melphalan results in decreased expression of ZFHX4 mRNA CTD PMID:22363485 NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228 		JBrowse link
G Zfp277 zinc finger protein 277 decreases expression ISO Melphalan results in decreased expression of ZNF277 mRNA CTD PMID:22363485 NCBI chr 6:57,383,944...57,512,785
Ensembl chr 6:57,383,951...57,512,765 		JBrowse link
G Zfp438 zinc finger protein 438 decreases expression ISO Melphalan results in decreased expression of ZNF438 mRNA CTD PMID:22363485 NCBI chr17:52,426,221...52,547,472
Ensembl chr17:52,426,221...52,547,472 		JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO Melphalan results in decreased expression of ZNF521 mRNA CTD PMID:22363485 NCBI chr18:4,775,952...5,068,592
Ensembl chr18:4,787,295...5,068,458 		JBrowse link
G Zfp618 zinc finger protein 618 decreases expression ISO Melphalan results in decreased expression of ZNF618 mRNA CTD PMID:22363485 NCBI chr 5:76,398,514...76,564,837
Ensembl chr 5:76,398,366...76,564,834 		JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO Melphalan results in decreased expression of ZSWIM5 mRNA CTD PMID:22363485 NCBI chr 5:130,346,519...130,463,791
Ensembl chr 5:130,343,034...130,463,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        immunomodulator 15059
          immunosuppressive agent 13927
            melphalan 274
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    main group molecular entity 19761
                      s-block molecular entity 19612
                        hydrogen molecular entity 19601
                          hydrides 19077
                            organic hydride 18671
                              organic fundamental parent 18671
                                hydrocarbon 18417
                                  cyclic hydrocarbon 17226
                                    monocyclic hydrocarbon 6094
                                      annulene 5745
                                        aromatic annulene 5745
                                          benzene 5745
                                            alkylbenzene 3442
                                              methylbenzene 3307
                                                toluene 3174
                                                  benzyl group 2577
                                                    phenylalanine 2577
                                                      L-phenylalanine 2319
                                                        L-phenylalanine derivative 2280
                                                          melphalan 274
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