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Accession:CHEBI:28864 term browser browse the term
Definition:A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.
Synonyms:exact_synonym: (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
 related_synonym: 3'-Deoxykanamycin B;   Formula=C18H37N5O9;   InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1;   InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N;   Nebramycin 6;   Nebramycin factir 6;   O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine;   SMILES=NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O;   Tobracin (TN);   Tobrex (TN)
 alt_id: CHEBI:19849;   CHEBI:45933;   CHEBI:9610
 xref: CAS:32986-56-4 "ChemIDplus";   CAS:32986-56-4 "KEGG COMPOUND";   DrugBank:DB00684;   Drug_Central:2684 "DrugCentral";   KEGG:C00397;   KEGG:D00063;   LINCS:LSM-6534
 xref_mesh: MESH:D014031
 xref: PDBeChem:TOY;   PMID:11000679 "Europe PMC";   PMID:11072877 "Europe PMC";   PMID:11459219 "Europe PMC";   PMID:11478352 "Europe PMC";   PMID:14961139 "Europe PMC";   PMID:15813341 "Europe PMC";   PMID:16205136 "Europe PMC";   PMID:16239129 "Europe PMC";   PMID:16478137 "Europe PMC";   PMID:16650821 "Europe PMC";   PMID:17150225 "Europe PMC";   PMID:18331849 "Europe PMC";   PMID:19072156 "Europe PMC";   PMID:19220547 "Europe PMC";   PMID:19340717 "Europe PMC";   PMID:19465435 "Europe PMC";   PMID:20000576 "Europe PMC";   PMID:20884302 "Europe PMC";   PMID:20938669 "Europe PMC";   PMID:21275493 "Europe PMC";   PMID:21343445 "Europe PMC";   PMID:21357290 "Europe PMC";   PMID:21396748 "Europe PMC";   PMID:21414310 "Europe PMC";   PMID:21429824 "Europe PMC";   PMID:21438171 "Europe PMC";   PMID:21530479 "Europe PMC";   PMID:21592592 "Europe PMC";   PMID:21726492 "Europe PMC";   PMID:21756818 "Europe PMC";   PMID:21796931 "Europe PMC";   PMID:21815282 "Europe PMC";   Reaxys:1357507 "Reaxys";   Wikipedia:Tobramycin
 cyclic_relationship: is_conjugate_base_of CHEBI:73678

show annotations for term's descendants       view all columns           Sort by:
tobramycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anpep alanyl aminopeptidase, membrane JBrowse link 1 141,561,364 141,604,249 RGD:6480464
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        antimicrobial agent 17199
          tobramycin 9
            nebramycin 5' 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            heteroorganic entity 19055
                              organochalcogen compound 18777
                                organooxygen compound 18689
                                  carbohydrates and carbohydrate derivatives 12088
                                    carbohydrate 12088
                                      carbohydrate derivative 11728
                                        glycosyl compound 10787
                                          glycoside 9136
                                            aminoglycoside 8348
                                              aminoglycoside antibiotic 2532
                                                kanamycins 24
                                                  kanamycin B 9
                                                    tobramycin 9
                                                      nebramycin 5' 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.