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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:beta-D-glucuronic acid
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Accession:CHEBI:28860 term browser browse the term
Definition:A D-glucopyranuronic acid in which the anomeric centre has beta-configuration.
Synonyms:exact_synonym: (2S,3S,4S,5R,6R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-carboxylic acid
 related_synonym: Formula=C6H10O7;   GlcAb;   GlcAbeta;   InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1;   InChIKey=AEMOLEFTQBMNLQ-QIUUJYRFSA-N;   SMILES=O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O;   beta-D-GlcpA;   beta-D-Glucopyranuronic acid
 alt_id: CHEBI:10395;   CHEBI:21016;   CHEBI:40973
 xref: Beilstein:1427744;   Gmelin:2497864;   KEGG:C08350;   KNApSAcK:C00001123;   MetaCyc:CPD-12521;   PDBeChem:BDP;   PMID:19443021;   PMID:22770225;   PMID:25568069;   PMID:31537530;   PMID:35774810;   Reaxys:1427744;   Wikipedia:Glucuronic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:85313


show annotations for term's descendants           Sort by:
acetaminophen O-beta-D-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases activity
affects export
multiple interactions		 ISO
EXP		 acetaminophen glucuronide results in increased activity of ABCC3 protein
ABCC3 protein affects the export of acetaminophen glucuronide
Ethinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]		 CTD PMID:16250050 PMID:16554369 PMID:17569508 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ins2 insulin 2 increases abundance ISO INS protein results in increased abundance of acetaminophen glucuronide CTD PMID:26739624 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO OGT gene mutant form inhibits the reaction [Acetaminophen results in increased abundance of acetaminophen glucuronide] CTD PMID:29325178 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
androsterone 3-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho multiple interactions ISO androsterone glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] CTD PMID:14701853 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        biochemical role 19501
          metabolite 19486
            beta-D-glucuronic acid 4
              2-Me-alpha-D-Fucp4NAc-(1->4)-beta-D-GlcpA 0
              3-indole carboxylic acid glucuronide 0
              5-(3',5'-dihydroxyphenyl)-valeric acid-O-glucuronide 0
              5alpha-androstane-3beta,17beta-diol 3-O-(beta-D-glucuronide) 0
              acetaminophen O-beta-D-glucosiduronic acid 3
              alpha-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
              androsterone 3-glucosiduronic acid 1
              beta-D-GlcpA-(1->3)-beta-D-GalpNAc4S 0
              beta-D-GlcpA-(1->3)-beta-D-GalpNAc6S 0
              beta-D-GlcpA-(1->4)-D-Xylp 0
              beta-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
              beta-D-Xylp-(1->3)-beta-D-GlcpA 0
              beta-D-Xylp-(1->4)-beta-D-GlcpA 0
              beta-D-glucuronamide 0
              cytosylglucuronic acid 0
              dehydroisoandrosterone 3-glucuronide 0
              kaempferol O-glucuronide + 0
              luteolin O-glucuronoside + 0
              methyl beta-D-glucopyranuronate 0
              methyl beta-D-glucuronoside 0
              mycophenolic acid O-acyl-glucuronide 0
              myricetin O-glucuronide + 0
              octanoyl-beta-D-glucuronide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        monocarboxylic acid 17903
                                          uronic acid 16
                                            hexuronic acid 16
                                              glucuronic acids 15
                                                glucuronic acid 13
                                                  D-glucuronic acid 12
                                                    D-glucopyranuronic acid 12
                                                      beta-D-glucuronic acid 4
                                                        2-Me-alpha-D-Fucp4NAc-(1->4)-beta-D-GlcpA 0
                                                        3-indole carboxylic acid glucuronide 0
                                                        5-(3',5'-dihydroxyphenyl)-valeric acid-O-glucuronide 0
                                                        5alpha-androstane-3beta,17beta-diol 3-O-(beta-D-glucuronide) 0
                                                        acetaminophen O-beta-D-glucosiduronic acid 3
                                                        alpha-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
                                                        androsterone 3-glucosiduronic acid 1
                                                        beta-D-GlcpA-(1->3)-beta-D-GalpNAc4S 0
                                                        beta-D-GlcpA-(1->3)-beta-D-GalpNAc6S 0
                                                        beta-D-GlcpA-(1->4)-D-Xylp 0
                                                        beta-D-GlcpNAc-(1->4)-beta-D-GlcpA 0
                                                        beta-D-Xylp-(1->3)-beta-D-GlcpA 0
                                                        beta-D-Xylp-(1->4)-beta-D-GlcpA 0
                                                        beta-D-glucuronamide 0
                                                        cytosylglucuronic acid 0
                                                        dehydroisoandrosterone 3-glucuronide 0
                                                        kaempferol O-glucuronide + 0
                                                        luteolin O-glucuronoside + 0
                                                        methyl beta-D-glucopyranuronate 0
                                                        methyl beta-D-glucuronoside 0
                                                        mycophenolic acid O-acyl-glucuronide 0
                                                        myricetin O-glucuronide + 0
                                                        octanoyl-beta-D-glucuronide 0
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