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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:flavonols
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Accession:CHEBI:28802 term browser browse the term
Definition:Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group.
Synonyms:related_synonym: 3-hydroxyflavones;   Formula=C15HO3R9;   SMILES=Oc1c(oc2c([*])c([*])c([*])c([*])c2c1=O)-c1c([*])c([*])c([*])c([*])c1[*];   a flavonol
 alt_id: CHEBI:13639;   CHEBI:24052;   CHEBI:71969
 xref_mesh: MESH:D044948
 xref: MetaCyc:Flavonols;   Wikipedia:Flavonol
 cyclic_relationship: is_conjugate_acid_of CHEBI:58588


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icariin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 increases activity EXP icariin results in increased activity of NOS3 protein CTD PMID:17438405 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
kaempferol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] CTD PMID:15266218 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G CPNE6 copine 6 decreases activity EXP kaempferol results in decreased activity of DHRS4 protein CTD PMID:17827741 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
quercetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] CTD PMID:15266218 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G CPNE6 copine 6 decreases activity EXP Quercetin results in decreased activity of DHRS4 protein CTD PMID:17827741 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
G HSP70 heat shock protein 70 decreases expression EXP Quercetin results in decreased expression of HSP70 protein CTD PMID:17009600 NCBI chr12:1,285,282...1,287,670 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 494
    chemical entity 501
      molecular entity 494
        polyatomic entity 487
          heteroatomic molecular entity 438
            hydroxides 418
              organic hydroxy compound 140
                hydroxyflavone 11
                  flavonols 4
                    3,3',4',5,7-pentahydroxy-8-methoxyflavone 0
                    7,4'-dimethylkaempferol 0
                    7-hydroxyflavonol + 3
                    8-(1,1-dimethylallyl)galangin 0
                    8-lavandulylkaempferol 0
                    dorsilurin I 0
                    dorsilurin K 0
                    eupatin 0
                    eupatolitin 0
                    flavonol + 0
                    flavonol 3-O-(6-O-malonyl-beta-D-glucoside) 0
                    flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s + 0
                    flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s 0
                    flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s + 0
                    flavonol 3-O-beta-D-glucoside + 0
                    flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                    flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                    flavonol 3-O-glycoside 0
                    flavonol 7-O-beta-D-glucoside + 0
                    icariin 1
                    kaempferol + 2
                    kaempferol 3-O-beta-L-glucopyranoside 0
                    kaempferol 4'-O-beta-D-glucopyranoside 0
                    kaempferol 5-O-beta-D-glucopyranoside 0
                    kaempferol 5-O-beta-L-glucopyranoside 0
                    kaempferol 7-O-beta-D-galactopyranoside 0
                    kaempferol 7-O-beta-D-glucopyranoside 0
                    macaranone A 0
                    macaranone B 0
                    myricetin 3'-O-alpha-D-glucopyranoside 0
                    myricetin 3'-O-beta-D-glucopyranoside 0
                    myricetin 4'-O-alpha-D-glucopyranoside 0
                    myricetin 5-O-glucuronide 0
                    myricetin 7-O-beta-D-glucopyranoside 0
                    myricetin 7-O-glucuronide 0
                    ombuin 0
                    papyriflavonol A 0
                    patuletin 0
                    quercetagetin + 0
                    quercetin 4'-O-beta-D-glucopyranoside 0
                    quercetin 5,7,3',4'-tetramethyl ether 0
                    quercetin 7,3',4'-trimethyl ether 0
                    quercetin 7,4'-di-O-beta-D-glucoside 0
                    quercetin 7-O-alpha-D-rhamnopyranoside 0
                    quercetin 7-O-alpha-L-rhamnopyranoside 0
                    quercetin 7-O-beta-D-glucoside 0
                    quercetin 7-O-beta-L-rhamnopyranoside 0
                    rhamnocitrin 0
                    tambulin 0
                    velloquercetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 494
    subatomic particle 494
      composite particle 494
        hadron 501
          baryon 494
            nucleon 494
              atomic nucleus 494
                atom 494
                  main group element atom 487
                    p-block element atom 487
                      carbon group element atom 476
                        carbon atom 482
                          organic molecular entity 475
                            organic molecule 466
                              organic cyclic compound 449
                                organic heterocyclic compound 419
                                  oxacycle 68
                                    benzopyran 28
                                      1-benzopyran 19
                                        flavonoid 12
                                          anthoxanthin 11
                                            flavones 11
                                              hydroxyflavone 11
                                                flavonols 4
                                                  3,3',4',5,7-pentahydroxy-8-methoxyflavone 0
                                                  7,4'-dimethylkaempferol 0
                                                  7-hydroxyflavonol + 3
                                                  8-(1,1-dimethylallyl)galangin 0
                                                  8-lavandulylkaempferol 0
                                                  dorsilurin I 0
                                                  dorsilurin K 0
                                                  eupatin 0
                                                  eupatolitin 0
                                                  flavonol + 0
                                                  flavonol 3-O-(6-O-malonyl-beta-D-glucoside) 0
                                                  flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s + 0
                                                  flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s 0
                                                  flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s + 0
                                                  flavonol 3-O-beta-D-glucoside + 0
                                                  flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                                                  flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                                                  flavonol 3-O-glycoside 0
                                                  flavonol 7-O-beta-D-glucoside + 0
                                                  icariin 1
                                                  kaempferol + 2
                                                  kaempferol 3-O-beta-L-glucopyranoside 0
                                                  kaempferol 4'-O-beta-D-glucopyranoside 0
                                                  kaempferol 5-O-beta-D-glucopyranoside 0
                                                  kaempferol 5-O-beta-L-glucopyranoside 0
                                                  kaempferol 7-O-beta-D-galactopyranoside 0
                                                  kaempferol 7-O-beta-D-glucopyranoside 0
                                                  macaranone A 0
                                                  macaranone B 0
                                                  myricetin 3'-O-alpha-D-glucopyranoside 0
                                                  myricetin 3'-O-beta-D-glucopyranoside 0
                                                  myricetin 4'-O-alpha-D-glucopyranoside 0
                                                  myricetin 5-O-glucuronide 0
                                                  myricetin 7-O-beta-D-glucopyranoside 0
                                                  myricetin 7-O-glucuronide 0
                                                  ombuin 0
                                                  papyriflavonol A 0
                                                  patuletin 0
                                                  quercetagetin + 0
                                                  quercetin 4'-O-beta-D-glucopyranoside 0
                                                  quercetin 5,7,3',4'-tetramethyl ether 0
                                                  quercetin 7,3',4'-trimethyl ether 0
                                                  quercetin 7,4'-di-O-beta-D-glucoside 0
                                                  quercetin 7-O-alpha-D-rhamnopyranoside 0
                                                  quercetin 7-O-alpha-L-rhamnopyranoside 0
                                                  quercetin 7-O-beta-D-glucoside 0
                                                  quercetin 7-O-beta-L-rhamnopyranoside 0
                                                  rhamnocitrin 0
                                                  tambulin 0
                                                  velloquercetin 0
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