Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:coumarin
go back to main search page
Accession:CHEBI:28794 term browser browse the term
Definition:A chromenone having the keto group located at the 2-position.
Synonyms:related_synonym: 1,2-Benzopyrone;   2-Propenoic acid, 3-(2-hydroxyphenyl)-, d-lactone;   2-Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone;   2H-1-Benzopyran-2-one;   2H-Chromen-2-one;   2H-benzo[b]pyran-2-one;   5,6-Benzo-2-pyrone;   Benzo-a-pyrone;   Benzo-alpha-pyrone;   Coumarine;   Coumarinic anhydride;   Cumarin;   Formula=C9H6O2;   InChI=1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H;   InChIKey=ZYGHJZDHTFUPRJ-UHFFFAOYSA-N;   Rattex;   SMILES=C=1C=CC=C2C1C=CC(=O)O2;   Tonka bean camphor;   cis-o-Coumarinic acid lactone;   o-Hydroxycinnamic acid lactone;   o-hydroxycinnamic acid delta-lactone
 alt_id: CHEBI:101256;   CHEBI:23402;   CHEBI:3906;   CHEBI:41552
 xref: Beilstein:383644;   CAS:91-64-5;   DrugBank:DB04665;   Drug_Central:738;   Gmelin:165222;   HMDB:HMDB0001218;   KEGG:C05851;   KEGG:D07751;   KNApSAcK:C00002460;   LINCS:LSM-2519
 xref_mesh: MESH:C030123
 xref: MetaCyc:COUMARIN;   PMID:17988284;   PMID:19025869;   PMID:21046436;   PMID:21462332;   PMID:21798343;   PMID:28166217;   PMID:8735869;   Reaxys:383644;   Wikipedia:Coumarin

show annotations for term's descendants           Sort by:
 
coumarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase decreases expression EXP coumarin results in decreased expression of AASS mRNA CTD PMID:18480146 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 affects expression EXP coumarin affects the expression of ABCB11 mRNA CTD PMID:16963487 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP coumarin results in increased expression of ABCC3 mRNA CTD PMID:18480146 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP coumarin results in increased expression of ACAA1 mRNA CTD PMID:18480146 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 affects expression EXP coumarin affects the expression of ACAA2 mRNA CTD PMID:16963487 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [haloxon results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Paraoxon results in increased phosphorylation of ACHE protein] CTD PMID:10421444 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Acly ATP citrate lyase affects expression EXP coumarin affects the expression of ACLY mRNA CTD PMID:16963487 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845 		JBrowse link
G Aco1 aconitase 1 affects expression EXP coumarin affects the expression of ACO1 mRNA CTD PMID:16963487 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression EXP coumarin results in increased expression of ACOT4 mRNA CTD PMID:18480146 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 increases expression ISO coumarin results in increased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO coumarin analog results in decreased expression of AIFM1 mRNA CTD PMID:32578917 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP coumarin results in increased expression of AKR1B8 mRNA CTD PMID:18480146 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression EXP coumarin results in decreased expression of AKR1C6 mRNA CTD PMID:18480146 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP coumarin affects the expression of AKR1D1 mRNA CTD PMID:16963487 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP coumarin results in increased expression of AKR7A3 mRNA CTD PMID:18480146 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO coumarin analog results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:32578917 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP coumarin results in increased expression of ALDH1A1 mRNA CTD PMID:18480146 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression EXP coumarin results in increased expression of ALOX5 mRNA CTD PMID:18480146 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Anxa7 annexin A7 increases expression EXP coumarin results in increased expression of ANXA7 mRNA CTD PMID:18480146 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287 		JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 decreases expression EXP coumarin results in decreased expression of APBB3 mRNA CTD PMID:18480146 NCBI chr18:29,497,865...29,504,995
Ensembl chr18:29,497,863...29,504,995 		JBrowse link
G Apcs amyloid P component, serum decreases expression EXP coumarin results in decreased expression of APCS mRNA CTD PMID:18480146 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575 		JBrowse link
G Arg1 arginase 1 affects expression EXP coumarin affects the expression of ARG1 mRNA CTD PMID:16963487 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP coumarin results in increased expression of ASNS mRNA CTD PMID:18480146 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP coumarin results in increased expression of ATPIF1 mRNA CTD PMID:18480146 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321 		JBrowse link
G Atrn attractin decreases expression EXP coumarin results in decreased expression of ATRN mRNA CTD PMID:18480146 NCBI chr 3:123,434,409...123,567,922
Ensembl chr 3:123,434,409...123,567,918 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP coumarin results in decreased expression of AVPR1A mRNA CTD PMID:18480146 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding affects expression EXP coumarin affects the expression of AZGP1 mRNA CTD PMID:16963487 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO coumarin analog results in increased expression of BAD mRNA CTD PMID:32578917 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO coumarin analog results in increased expression of BAK1 protein CTD PMID:31199928 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO coumarin analog results in increased expression of BAX mRNA; coumarin results in increased expression of BAX protein CTD PMID:15964220, PMID:32578917 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO coumarin analog results in increased expression of BBC3 protein CTD PMID:31199928 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP coumarin results in decreased expression of BBOX1 mRNA CTD PMID:18480146 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO coumarin analog results in decreased expression of BCL2 mRNA; coumarin results in decreased expression of BCL2 protein CTD PMID:15964220, PMID:32578917 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 increases expression EXP coumarin results in increased expression of BHLHA15 mRNA CTD PMID:18480146 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression
affects expression		 EXP coumarin results in decreased expression of BHMT mRNA
coumarin affects the expression of BHMT mRNA		 CTD PMID:16963487, PMID:18480146 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO coumarin analog results in increased expression of BID mRNA CTD PMID:32578917 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO coumarin analog results in decreased expression of BIRC5 mRNA CTD PMID:32578917 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP coumarin results in decreased expression of CA3 mRNA CTD PMID:18480146 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410 		JBrowse link
G Capn1 calpain 1 decreases expression ISO coumarin analog results in decreased expression of CAPN1 mRNA CTD PMID:32578917 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322 		JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO coumarin results in decreased activity of CA1 protein CTD PMID:22077347 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression
decreases activity		 EXP
ISO		 coumarin results in increased expression of CA2 mRNA
coumarin results in decreased activity of CA2 protein		 CTD PMID:18480146, PMID:22077347 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression		 ISO coumarin analog results in increased cleavage of CASP3 protein
coumarin analog results in increased expression of CASP3 mRNA		 CTD PMID:32578917 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 increases expression ISO coumarin analog results in increased expression of CASP8 mRNA CTD PMID:32578917 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 increases expression ISO coumarin analog results in increased expression of CASP9 mRNA CTD PMID:32578917 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 EXP
ISO		 coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]
coumarin analog results in decreased activity of CAT protein		 CTD PMID:21630391, PMID:32578917 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP coumarin results in increased expression of CBR1 mRNA CTD PMID:18480146 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793 		JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP coumarin results in decreased expression of CCNB2 mRNA CTD PMID:18480146 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO coumarin analog results in decreased expression of CCND1 mRNA CTD PMID:32578917 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccne1 cyclin E1 increases expression
decreases expression		 EXP
ISO		 coumarin results in increased expression of CCNE1 mRNA
coumarin analog results in decreased expression of CCNE1 mRNA		 CTD PMID:18480146, PMID:32578917 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Ccne2 cyclin E2 increases expression EXP coumarin results in increased expression of CCNE2 mRNA CTD PMID:18480146 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO coumarin analog results in increased expression of CDH1 mRNA; coumarin analog results in increased expression of CDH1 protein CTD PMID:32578917 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdh2 cadherin 2 decreases expression ISO coumarin analog results in decreased expression of CDH2 mRNA CTD PMID:32578917 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO coumarin analog results in decreased expression of CDK2 mRNA CTD PMID:32578917 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO coumarin analog results in decreased expression of CDK4 mRNA CTD PMID:32578917 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO coumarin analog results in increased expression of CDKN1A mRNA CTD PMID:32578917 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP coumarin results in decreased expression of CDKN3 mRNA CTD PMID:18480146 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP coumarin affects the expression of CDO1 mRNA CTD PMID:16963487 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO coumarin results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821 		JBrowse link
G Cisd3 CDGSH iron sulfur domain 3 increases expression EXP coumarin results in increased expression of CISD3 mRNA CTD PMID:18480146 NCBI chr10:85,628,579...85,631,656
Ensembl chr10:85,628,491...85,631,657 		JBrowse link
G Cldn3 claudin 3 decreases expression ISO coumarin analog results in decreased expression of CLDN3 mRNA CTD PMID:32578917 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813 		JBrowse link
G Cldn4 claudin 4 decreases expression ISO coumarin analog results in decreased expression of CLDN4 mRNA CTD PMID:32578917 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression EXP coumarin results in increased expression of COQ6 mRNA CTD PMID:18480146 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP coumarin results in increased expression of CREG mRNA CTD PMID:18480146 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675 		JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression EXP coumarin results in increased expression of CRELD2 mRNA CTD PMID:18480146 NCBI chr 7:129,812,746...129,819,641
Ensembl chr 7:129,812,789...129,819,634 		JBrowse link
G Cryab crystallin, alpha B decreases expression EXP coumarin results in decreased expression of CRYAB mRNA CTD PMID:18480146 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545 		JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP coumarin results in increased expression of CRYL1 mRNA CTD PMID:18480146 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP coumarin results in decreased expression of CSAD mRNA CTD PMID:18480146 NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP coumarin results in decreased expression of CSRP1 mRNA CTD PMID:18480146 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051 		JBrowse link
G Ctf1 cardiotrophin 1 increases expression EXP coumarin results in increased expression of CTF1 mRNA CTD PMID:18480146 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296 		JBrowse link
G Cth cystathionine gamma-lyase affects expression EXP coumarin affects the expression of CTH mRNA CTD PMID:16963487 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO coumarin analog results in decreased expression of CTNNB1 mRNA CTD PMID:32578917 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Ctsb cathepsin B increases expression ISO coumarin analog results in increased expression of CTSB mRNA CTD PMID:32578917 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP coumarin results in decreased expression of CXCL12 mRNA CTD PMID:18480146 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cyb561 cytochrome b-561 increases expression EXP coumarin results in increased expression of CYB561 mRNA CTD PMID:18480146 NCBI chr10:94,136,993...94,147,567
Ensembl chr10:94,136,993...94,147,621 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO coumarin analog results in increased expression of CYCS mRNA CTD PMID:32578917 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
affects expression		 EXP coumarin results in decreased expression of CYP1A2 mRNA
coumarin affects the expression of CYP1A2 mRNA		 CTD PMID:16963487, PMID:18480146 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases hydroxylation EXP CYP2A6 protein results in increased hydroxylation of coumarin CTD PMID:12919726 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 affects metabolic processing ISO CYP2A5 protein affects the metabolism of coumarin CTD PMID:10646973 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP coumarin results in decreased expression of CYP2C mRNA CTD PMID:18480146 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects localization EXP coumarin affects the localization of CYP2E1 protein CTD PMID:28803882 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects expression EXP coumarin affects the expression of CYP3A2 mRNA CTD PMID:16963487 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression EXP coumarin results in decreased expression of CYP51 mRNA CTD PMID:18480146 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP coumarin results in decreased expression of CYP7A1 mRNA CTD PMID:18480146 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression EXP coumarin results in increased expression of DDIT4L mRNA CTD PMID:18480146 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131 		JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression EXP coumarin results in increased expression of DDOST mRNA CTD PMID:18480146 NCBI chr 5:156,668,924...156,676,036
Ensembl chr 5:156,668,712...156,676,035 		JBrowse link
G Ddx31 DEAD-box helicase 31 decreases expression EXP coumarin results in decreased expression of DDX31 mRNA CTD PMID:18480146 NCBI chr 3:7,422,871...7,488,299
Ensembl chr 3:7,422,820...7,488,617 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression EXP coumarin results in increased expression of DNAJB11 mRNA CTD PMID:18480146 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 affects expression EXP coumarin affects the expression of DNAJB9 mRNA CTD PMID:16963487 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression EXP coumarin results in increased expression of DNAJC3 mRNA CTD PMID:18480146 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 increases expression EXP coumarin results in increased expression of DSCC1 mRNA CTD PMID:18480146 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP coumarin affects the expression of ECI1 mRNA CTD PMID:16963487 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression EXP coumarin results in increased expression of EEF1E1 mRNA CTD PMID:18480146 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 increases expression EXP coumarin results in increased expression of ELL3 mRNA CTD PMID:18480146 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 increases expression EXP coumarin results in increased expression of EME2 mRNA CTD PMID:18480146 NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO coumarin results in increased expression of EPHX1 mRNA CTD PMID:17311802 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G F9 coagulation factor IX increases response to substance ISO F9 exon polymorphism results in increased susceptibility to coumarin; F9 protein mutant form results in increased susceptibility to coumarin CTD PMID:11307814 NCBI chr  X:143,097,507...143,141,791
Ensembl chr  X:143,097,525...143,141,794 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP coumarin results in decreased expression of FADS1 mRNA CTD PMID:18480146 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138 		JBrowse link
G Fam111a family with sequence similarity 111, member A increases expression EXP coumarin results in increased expression of FAM111A mRNA CTD PMID:18480146 NCBI chr 1:229,003,778...229,019,532
Ensembl chr 1:229,003,961...229,019,527 		JBrowse link
G Fasn fatty acid synthase affects expression EXP coumarin affects the expression of FASN mRNA CTD PMID:16963487 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression EXP coumarin results in increased expression of FEN1 mRNA CTD PMID:18480146 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886 		JBrowse link
G Fgg fibrinogen gamma chain affects expression EXP coumarin affects the expression of FGG mRNA CTD PMID:16963487 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514 		JBrowse link
G Fggy FGGY carbohydrate kinase domain containing decreases expression EXP coumarin results in decreased expression of FGGY mRNA CTD PMID:18480146 NCBI chr 5:114,516,860...114,901,571
Ensembl chr 5:114,516,889...114,901,564 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP coumarin results in increased expression of FKBP11 mRNA CTD PMID:18480146 NCBI chr 7:140,398,253...140,402,664
Ensembl chr 7:140,398,199...140,437,467 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP coumarin results in decreased expression of FMO1 mRNA CTD PMID:18480146 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347 		JBrowse link
G Gas5 growth arrest specific 5 increases expression EXP coumarin results in increased expression of GAS5 mRNA CTD PMID:18480146 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gckr glucokinase regulator decreases expression EXP coumarin results in decreased expression of GCKR mRNA CTD PMID:18480146 NCBI chr 6:26,355,296...26,385,761
Ensembl chr 6:26,355,296...26,385,761 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP coumarin results in increased expression of GCLC mRNA CTD PMID:18480146 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP coumarin results in increased expression of GCLM mRNA CTD PMID:18480146 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP coumarin results in increased expression of GJB2 mRNA CTD PMID:18480146 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277 		JBrowse link
G Gk glycerol kinase decreases expression EXP coumarin results in decreased expression of GK mRNA CTD PMID:18480146 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864 		JBrowse link
G Glb1 galactosidase, beta 1 increases expression EXP coumarin results in increased expression of GLB1 mRNA CTD PMID:18480146 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939 		JBrowse link
G Gldc glycine decarboxylase decreases expression EXP coumarin results in decreased expression of GLDC mRNA CTD PMID:18480146 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093 		JBrowse link
G Gpr108 G protein-coupled receptor 108 decreases expression EXP coumarin results in decreased expression of GPR108 mRNA CTD PMID:18480146 NCBI chr 9:9,704,300...9,714,767
Ensembl chr 9:9,704,346...9,714,755 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP coumarin affects the expression of GPX1 mRNA CTD PMID:16963487 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP coumarin results in increased expression of GSR mRNA CTD PMID:18480146 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO
EXP		 coumarin results in increased expression of GSTA1 protein; coumarin results in increased expression of GSTA2 protein
coumarin results in increased expression of GSTA3 protein		 CTD PMID:9794803, PMID:11309284 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO coumarin results in increased expression of GSTA3 protein CTD PMID:11309284 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP coumarin results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179 		JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO coumarin results in increased expression of GSTA1 protein; coumarin results in increased expression of GSTA2 protein CTD PMID:11309284 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP
ISO		 coumarin results in increased expression of GSTM3 protein
coumarin results in increased expression of GSTM5 protein		 CTD PMID:9794803, PMID:11309284 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO
EXP		 coumarin results in increased expression of GSTP1 protein CTD PMID:9794803, PMID:11309284 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP coumarin results in increased expression of GSTT1 mRNA; coumarin results in increased expression of GSTT1 protein CTD PMID:9794803, PMID:9855024, PMID:10413528 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Hal histidine ammonia lyase decreases expression EXP coumarin results in decreased expression of HAL mRNA CTD PMID:18480146 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP coumarin results in decreased expression of HAO2 mRNA CTD PMID:18480146 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions EXP coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein] CTD PMID:19647726 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO coumarin analog results in increased expression of HIF1A mRNA CTD PMID:32578917 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP coumarin results in increased expression of HMGCR mRNA CTD PMID:18480146 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 multiple interactions ISO coumarin analog inhibits the reaction [[HSD17B1 protein co-treated with NADP] results in increased reduction of Estrone] CTD PMID:21232530 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression EXP coumarin results in increased expression of HSP90B1 mRNA CTD PMID:18480146 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP coumarin results in increased expression of HSPA1B mRNA CTD PMID:18480146 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP coumarin results in increased expression of HYOU1 mRNA CTD PMID:18480146 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP coumarin results in decreased expression of IGFALS mRNA CTD PMID:18480146 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597 		JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression		 EXP
ISO		 coumarin results in increased expression of IL1B mRNA
coumarin analog results in decreased expression of IL1B protein		 CTD PMID:15135310, PMID:32578917 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 increases expression
decreases expression		 EXP
ISO		 coumarin results in increased expression of IL6 mRNA
coumarin analog results in decreased expression of IL6 mRNA; coumarin analog results in decreased expression of IL6 protein		 CTD PMID:15135310, PMID:32578917 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP coumarin results in increased expression of ISYNA1 mRNA CTD PMID:18480146 NCBI chr16:20,589,497...20,592,333
Ensembl chr16:20,589,481...20,592,449 		JBrowse link
G Josd2 Josephin domain containing 2 increases expression EXP coumarin results in increased expression of JOSD2 mRNA CTD PMID:18480146 NCBI chr 1:100,473,426...100,477,352
Ensembl chr 1:100,473,643...100,477,351 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 increases expression EXP coumarin results in increased expression of KCNK2 mRNA CTD PMID:18480146 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476 		JBrowse link
G Kdr kinase insert domain receptor increases expression ISO coumarin analog results in increased expression of KDR mRNA CTD PMID:32578917 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP coumarin results in decreased expression of KIF20A mRNA CTD PMID:18480146 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814 		JBrowse link
G Klf2 Kruppel-like factor 2 decreases expression EXP coumarin results in decreased expression of KLF2 mRNA CTD PMID:18480146 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037 		JBrowse link
G Krt19 keratin 19 decreases expression EXP coumarin results in decreased expression of KRT19 mRNA CTD PMID:18480146 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561 		JBrowse link
G Kynu kynureninase decreases expression EXP coumarin results in decreased expression of KYNU mRNA CTD PMID:18480146 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928 		JBrowse link
G Lad1 ladinin 1 increases expression EXP coumarin results in increased expression of LAD1 mRNA CTD PMID:18480146 NCBI chr13:52,645,257...52,659,619
Ensembl chr13:52,645,257...52,659,619 		JBrowse link
G Lmf2 lipase maturation factor 2 increases expression EXP coumarin results in increased expression of LMF2 mRNA CTD PMID:18480146 NCBI chr 7:130,322,018...130,326,470
Ensembl chr 7:130,322,020...130,326,470 		JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP coumarin affects the expression of LRP3 mRNA CTD PMID:16963487 NCBI chr 1:91,447,308...91,462,603
Ensembl chr 1:91,448,361...91,462,603 		JBrowse link
G Mat1a methionine adenosyltransferase 1A affects expression EXP coumarin affects the expression of MAT1A mRNA CTD PMID:16963487 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133 		JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression EXP coumarin results in decreased expression of MBL2 mRNA CTD PMID:18480146 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression EXP coumarin results in increased expression of MCM2 mRNA CTD PMID:18480146 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression EXP coumarin results in increased expression of MCM3 mRNA CTD PMID:18480146 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression EXP coumarin results in increased expression of MCM4 mRNA CTD PMID:18480146 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression EXP coumarin results in increased expression of MCM5 mRNA CTD PMID:18480146 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278 		JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO coumarin analog results in decreased expression of MDM2 mRNA CTD PMID:32578917 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mgp matrix Gla protein decreases expression ISO coumarin results in decreased expression of MGP mRNA CTD PMID:19350115 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression EXP coumarin results in increased expression of MGST2 mRNA CTD PMID:18480146 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 decreases expression EXP coumarin results in decreased expression of MGST3 mRNA CTD PMID:18480146 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO coumarin analog results in decreased expression of MMP2 mRNA CTD PMID:32578917 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO coumarin analog results in decreased expression of MMP9 mRNA
coumarin analog results in decreased expression of and results in decreased activity of MMP9 protein		 CTD PMID:32578917 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mms22l MMS22-like, DNA repair protein increases expression EXP coumarin results in increased expression of MMS22L mRNA CTD PMID:18480146 NCBI chr 5:38,844,502...38,960,989
Ensembl chr 5:38,844,488...38,961,035 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 affects expression EXP coumarin affects the expression of MSMO1 mRNA CTD PMID:16963487 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP coumarin results in increased expression of MT1A mRNA CTD PMID:18480146 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724 		JBrowse link
G Mt2A metallothionein 2A increases expression EXP coumarin results in increased expression of MT2A mRNA CTD PMID:18480146 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression EXP coumarin results in decreased expression of NECTIN2 mRNA CTD PMID:18480146 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity
increases activity		 ISO coumarin affects the activity of NFE2L2 protein
coumarin results in increased activity of NFE2L2 protein		 CTD PMID:11309284, PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nol3 nucleolar protein 3 increases expression EXP coumarin results in increased expression of NOL3 mRNA CTD PMID:18480146 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649 		JBrowse link
G Nol8 nucleolar protein 8 increases expression EXP coumarin results in increased expression of NOL8 mRNA CTD PMID:18480146 NCBI chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression EXP coumarin results in increased expression of NOP56 mRNA CTD PMID:18480146 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP
ISO		 coumarin results in increased expression of NOS2 mRNA
coumarin analog results in increased expression of NOS2 mRNA; coumarin analog results in increased expression of NOS2 protein		 CTD PMID:15135310, PMID:32578917 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO
EXP		 coumarin results in increased expression of NQO1 mRNA; coumarin results in increased expression of NQO1 protein CTD PMID:11309284, PMID:17311802, PMID:18480146 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression EXP coumarin results in increased expression of NR0B2 mRNA CTD PMID:18480146 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP coumarin results in increased expression of NR1D2 mRNA CTD PMID:18480146 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP coumarin results in decreased expression of NREP mRNA CTD PMID:18480146 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445 		JBrowse link
G Nrtn neurturin increases expression EXP coumarin results in increased expression of NRTN mRNA CTD PMID:18480146 NCBI chr 9:10,299,881...10,306,599
Ensembl chr 9:10,305,470...10,306,597 		JBrowse link
G Ntng1 netrin G1 decreases expression EXP coumarin results in decreased expression of NTNG1 mRNA CTD PMID:18480146 NCBI chr 2:212,695,464...213,073,046
Ensembl chr 2:212,696,624...212,852,870 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP coumarin results in increased expression of NUPR1 mRNA CTD PMID:18480146 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524 		JBrowse link
G Oaf out at first homolog decreases expression EXP coumarin results in decreased expression of OAF mRNA CTD PMID:18480146 NCBI chr 8:47,511,718...47,529,689
Ensembl chr 8:47,511,719...47,529,689 		JBrowse link
G Oat ornithine aminotransferase decreases expression EXP coumarin results in decreased expression of OAT mRNA CTD PMID:18480146 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070 		JBrowse link
G Ogn osteoglycin decreases expression EXP coumarin results in decreased expression of OGN mRNA CTD PMID:18480146 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
decreases expression
increases cleavage
multiple interactions		 ISO coumarin results in decreased activity of PARP1 protein
coumarin analog results in decreased expression of PARP1 mRNA
coumarin analog results in increased cleavage of PARP1 protein
[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]; [coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]		 CTD PMID:17669606, PMID:31199928, PMID:32578917 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression EXP coumarin results in increased expression of PCK2 mRNA CTD PMID:18480146 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO coumarin analog results in increased expression of PCNA mRNA CTD PMID:32578917 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP coumarin results in decreased expression of PDE4B mRNA CTD PMID:18480146 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression EXP coumarin results in increased expression of PDIA3 mRNA CTD PMID:18480146 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP coumarin results in increased expression of PDIA4 mRNA CTD PMID:18480146 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 decreases expression EXP coumarin results in decreased expression of PDK2 mRNA CTD PMID:18480146 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP coumarin results in increased expression of PLA2G12A mRNA CTD PMID:18480146 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit increases expression EXP coumarin results in increased expression of POLD1 mRNA CTD PMID:18480146 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit increases expression EXP coumarin results in increased expression of POLD2 mRNA CTD PMID:18480146 NCBI chr14:86,111,416...86,117,578
Ensembl chr14:86,111,294...86,117,578 		JBrowse link
G Polr1e RNA polymerase I subunit E increases expression EXP coumarin results in increased expression of POLR1E mRNA CTD PMID:18480146 NCBI chr 5:60,572,573...60,588,097
Ensembl chr 5:60,572,577...60,588,240 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP coumarin results in increased expression of PTGR1 mRNA CTD PMID:18480146 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441 		JBrowse link
G R3hdm1 R3H domain containing 1 increases expression EXP coumarin results in increased expression of R3HDM1 mRNA CTD PMID:18480146 NCBI chr13:44,812,567...44,950,762
Ensembl chr13:44,812,567...44,950,762 		JBrowse link
G R3hdm2 R3H domain containing 2 decreases expression EXP coumarin results in decreased expression of R3HDM2 mRNA CTD PMID:18480146 NCBI chr 7:70,677,226...70,805,255
Ensembl chr 7:70,697,050...70,805,221 		JBrowse link
G Rab3d RAB3D, member RAS oncogene family increases expression EXP coumarin results in increased expression of RAB3D mRNA CTD PMID:18480146 NCBI chr 8:22,920,238...22,929,368
Ensembl chr 8:22,918,699...22,929,294 		JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP coumarin results in increased expression of RBM3 mRNA CTD PMID:18480146 NCBI chr  X:15,098,880...15,102,344
Ensembl chr  X:15,098,904...15,102,340 		JBrowse link
G Rbp1 retinol binding protein 1 decreases expression EXP coumarin results in decreased expression of RBP1 mRNA CTD PMID:18480146 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842 		JBrowse link
G RGD1560171 similar to PRO0149 protein increases expression EXP coumarin results in increased expression of RGD1560171 mRNA CTD PMID:18480146 NCBI chr  X:143,681,714...143,683,171
Ensembl chr  X:143,682,099...143,682,917 		JBrowse link
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase decreases expression EXP coumarin results in decreased expression of RGD1564865 mRNA CTD PMID:18480146 NCBI chr17:69,468,427...69,497,132
Ensembl chr17:69,468,427...69,497,132 		JBrowse link
G Rgn regucalcin decreases expression EXP coumarin results in decreased expression of RGN mRNA CTD PMID:18480146 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression EXP coumarin results in decreased expression of RGS8 mRNA CTD PMID:18480146 NCBI chr13:71,086,654...71,141,820
Ensembl chr13:71,086,745...71,141,075 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression EXP coumarin results in decreased expression of RPRM mRNA CTD PMID:18480146 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718 		JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression EXP coumarin results in increased expression of RT1-BA mRNA CTD PMID:18480146 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression EXP coumarin results in increased expression of HLA-DMA mRNA CTD PMID:18480146 NCBI chr20:3,935,512...3,938,915
Ensembl chr20:5,240,975...5,244,386 		JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP coumarin results in increased expression of RT1-EC2 mRNA CTD PMID:18480146
G Saraf store-operated calcium entry-associated regulatory factor increases expression EXP coumarin results in increased expression of SARAF mRNA CTD PMID:18480146 NCBI chr16:61,735,189...61,753,438
Ensembl chr16:61,735,181...61,753,476 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP coumarin results in decreased expression of SCD1 mRNA CTD PMID:18480146 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 increases expression EXP coumarin results in increased expression of SDF2L1 mRNA CTD PMID:18480146 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513 		JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase increases expression EXP coumarin results in increased expression of SEL1L mRNA CTD PMID:18480146 NCBI chr 6:115,572,683...115,616,904
Ensembl chr 6:115,572,649...115,616,859 		JBrowse link
G Sema6d semaphorin 6D increases expression EXP coumarin results in increased expression of SEMA6D mRNA CTD PMID:18480146 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050 		JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression EXP coumarin results in increased expression of SLC17A1 mRNA CTD PMID:18480146 NCBI chr17:43,473,048...43,504,645 JBrowse link
G Slc17a3 solute carrier family 17 member 3 increases expression EXP coumarin results in increased expression of SLC17A3 mRNA CTD PMID:18480146 NCBI chr17:43,518,760...43,545,160
Ensembl chr17:43,518,655...43,543,185 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP coumarin results in increased expression of SLC1A2 mRNA CTD PMID:18480146 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP coumarin affects the expression of SLC27A2 mRNA CTD PMID:16963487 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531 		JBrowse link
G Slc28a2 solute carrier family 28 member 2 decreases expression EXP coumarin results in decreased expression of SLC28A2 mRNA CTD PMID:18480146 NCBI chr 3:114,355,003...114,647,382
Ensembl chr 3:114,355,798...114,647,382 		JBrowse link
G Slc35e3 solute carrier family 35, member E3 increases expression EXP coumarin results in increased expression of SLC35E3 mRNA CTD PMID:18480146 NCBI chr 7:60,765,077...60,778,136
Ensembl chr 7:60,765,079...60,778,136 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 decreases expression EXP coumarin results in decreased expression of SLC6A13 mRNA CTD PMID:18480146 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression EXP coumarin results in increased expression of SLC6A9 mRNA CTD PMID:18480146 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B increases expression EXP coumarin results in increased expression of SMPDL3B mRNA CTD PMID:18480146 NCBI chr 5:150,925,150...150,946,994
Ensembl chr 5:150,925,370...150,949,931 		JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO coumarin analog results in decreased expression of SNAI2 mRNA CTD PMID:32578917 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression EXP coumarin results in increased expression of SRXN1 mRNA CTD PMID:18480146 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases activity ISO coumarin results in increased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 affects expression EXP coumarin affects the expression of SULT1B1 mRNA CTD PMID:16963487 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 decreases expression EXP coumarin results in decreased expression of SULT1C1 mRNA CTD PMID:18480146 NCBI chr 9:4,931,038...4,978,847
Ensembl chr 9:4,930,818...4,978,892 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression EXP coumarin results in decreased expression of SULT1E1 mRNA CTD PMID:18480146 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression EXP coumarin results in decreased expression of SYCP3 mRNA CTD PMID:18480146 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251 		JBrowse link
G Syne4 spectrin repeat containing nuclear envelope family member 4 increases expression EXP coumarin results in increased expression of SYNE4 mRNA CTD PMID:18480146 NCBI chr 1:88,772,729...88,777,044
Ensembl chr 1:88,772,904...88,776,999
Ensembl chr 1:88,772,904...88,776,999 		JBrowse link
G Tfrc transferrin receptor increases expression EXP coumarin results in increased expression of TFRC mRNA CTD PMID:18480146 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO coumarin analog results in increased expression of TGFB1 mRNA CTD PMID:32578917 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Thra thyroid hormone receptor alpha increases expression EXP coumarin results in increased expression of THRA mRNA CTD PMID:18480146 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933 		JBrowse link
G Thrsp thyroid hormone responsive affects expression
decreases expression		 EXP coumarin affects the expression of THRSP mRNA
coumarin results in decreased expression of THRSP mRNA		 CTD PMID:16963487, PMID:18480146 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO coumarin analog results in increased expression of TIMP2 mRNA CTD PMID:32578917 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 increases expression ISO coumarin analog results in increased expression of TIMP4 mRNA CTD PMID:32578917 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467 		JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 increases expression EXP coumarin results in increased expression of TMED3 mRNA CTD PMID:18480146 NCBI chr 8:97,075,194...97,083,107
Ensembl chr 8:97,075,160...97,083,120 		JBrowse link
G Tnf tumor necrosis factor increases expression EXP
ISO		 coumarin results in increased expression of TNF mRNA
coumarin analog results in increased expression of TNF protein		 CTD PMID:15135310, PMID:32578917 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 decreases expression EXP coumarin results in decreased expression of TNFRSF9 mRNA CTD PMID:18480146 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO coumarin analog results in increased expression of TP53 mRNA; coumarin analog results in increased expression of TP53 protein CTD PMID:32578917 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO coumarin analog results in increased expression of TRADD mRNA CTD PMID:32578917 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572 		JBrowse link
G Trpc2 transient receptor potential cation channel subfamily C member 2 increases expression EXP coumarin results in increased expression of TRPC2 mRNA CTD PMID:18480146 NCBI chr 1:167,180,103...167,192,456
Ensembl chr 1:167,169,442...167,192,801 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP coumarin results in decreased expression of TSC22D1 mRNA CTD PMID:18480146 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153 		JBrowse link
G Tst thiosulfate sulfurtransferase affects expression EXP coumarin affects the expression of TST mRNA CTD PMID:16963487 NCBI chr 7:119,616,323...119,623,072
Ensembl chr 7:119,616,324...119,623,072 		JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A increases expression EXP coumarin results in increased expression of TTC39A mRNA CTD PMID:18480146 NCBI chr 5:129,024,505...129,083,226
Ensembl chr 5:129,043,675...129,082,442
Ensembl chr 5:129,043,675...129,082,442 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP coumarin results in increased expression of TXNRD1 mRNA CTD PMID:18480146 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP coumarin results in increased expression of UGDH mRNA CTD PMID:18480146 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B decreases expression EXP coumarin results in decreased expression of UGT2B mRNA CTD PMID:18480146 Ensembl chr14:22,375,955...22,534,720 JBrowse link
G Ust5r integral membrane transport protein UST5r decreases expression EXP coumarin results in decreased expression of UST5R mRNA CTD PMID:18480146 NCBI chr 1:224,457,895...224,533,994
Ensembl chr 1:224,457,900...224,533,219 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO coumarin analog results in increased expression of VEGFA mRNA CTD PMID:32578917 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vim vimentin decreases expression ISO coumarin analog results in decreased expression of VIM protein CTD PMID:32578917 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 decreases response to substance
increases response to substance		 ISO VKORC1 gene mutant form results in decreased susceptibility to coumarin
VKORC1 gene mutant form results in increased susceptibility to coumarin; VKORC1 promoter SNP results in increased susceptibility to coumarin		 CTD PMID:17849045, PMID:18278162 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP coumarin results in increased expression of WEE1 mRNA CTD PMID:18480146 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing increases expression EXP coumarin results in increased expression of YRDC mRNA CTD PMID:18480146 NCBI chr 5:142,845,265...142,850,110
Ensembl chr 5:142,845,114...142,850,111 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression ISO coumarin analog results in decreased expression of ZEB1 mRNA CTD PMID:32578917 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914 		JBrowse link
G Zfp444 zinc finger protein 444 increases expression EXP coumarin results in increased expression of ZFP444 mRNA CTD PMID:18480146 NCBI chr 1:71,380,856...71,400,781
Ensembl chr 1:71,379,559...71,400,388 		JBrowse link
G Zfp593 zinc finger protein 593 increases expression EXP coumarin results in increased expression of ZNF593 mRNA CTD PMID:18480146 NCBI chr 5:152,462,522...152,464,850
Ensembl chr 5:152,462,522...152,464,850 		JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression EXP coumarin results in increased expression of ZWINT mRNA CTD PMID:18480146 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766 		JBrowse link
3,4-dihydrocoumarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 affects expression ISO 3,4-dihydrocoumarin affects the expression of DDIT3 mRNA CTD PMID:22016648 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of DNAJA2 mRNA CTD PMID:22016648 NCBI chr19:22,569,999...22,588,143
Ensembl chr19:22,569,999...22,588,137 		JBrowse link
G Egf epidermal growth factor increases expression ISO 3,4-dihydrocoumarin results in increased expression of EGF mRNA CTD PMID:22016648 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of EPHX1 mRNA CTD PMID:22016648 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression ISO 3,4-dihydrocoumarin results in increased expression of HSD17B4 mRNA CTD PMID:22016648 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of HSP90AB1 mRNA CTD PMID:22016648 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO 3,4-dihydrocoumarin results in increased expression of HSPA1A mRNA CTD PMID:22016648 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Oat ornithine aminotransferase decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of OAT mRNA CTD PMID:22016648 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of PCK1 mRNA CTD PMID:22016648 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871 		JBrowse link
G Pon1 paraoxonase 1 affects metabolic processing ISO PON1 SNP affects the metabolism of 3,4-dihydrocoumarin CTD PMID:25027835 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 3,4-dihydrocoumarin results in increased expression of PRDX1 mRNA CTD PMID:22016648 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990 		JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of PRDX3 mRNA CTD PMID:22016648 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of PSMB8 mRNA CTD PMID:22016648 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of PTPMT1 mRNA CTD PMID:22016648 NCBI chr 3:79,734,961...79,743,737
Ensembl chr 3:79,734,961...79,743,737 		JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of RBP4 mRNA CTD PMID:22016648 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of SOD1 mRNA CTD PMID:22016648 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of TIMP2 mRNA CTD PMID:22016648 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO 3,4-dihydrocoumarin results in decreased expression of TUBB5 mRNA CTD PMID:22016648 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        dye 1296
          fluorescent dye 466
            coumarin 267
              3,4-dihydrocoumarin 18
              3-(4-chlorophenyl)-2H-1-benzopyran-2-one 0
              4-ethyl-7-hydroxy-3-(p-methoxyphenyl)coumarin 0
              5,6,7-trimethoxycoumarin 0
              6,8-difluoro-4-methylumbelliferyl phosphate 0
              6,8-difluoro-4-methylumbelliferyl phosphate (2-) 0
              7-[(6-hydroxy-2,5,5,8a-tetramethyl-4-oxo-1,4,4a,5,6,7,8,8a-octahydro-1-naphthalenyl)methoxy]-2H-chromen-2-one 0
              7-hydroxy-3-(4-methoxyphenyl)-4-methylcoumarin 0
              7-hydroxy-3-(4-methoxyphenyl)-4-propyl-2H-1-benzopyran-2-one 0
              7-methoxycoumarin-4-acetic acid 0
              daphnoretin 0
              licoarylcoumarin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  oxacycle 17185
                                    benzopyran 10135
                                      1-benzopyran 9851
                                        chromenes 931
                                          chromenone 851
                                            coumarins 573
                                              coumarin 267
                                                3,4-dihydrocoumarin 18
                                                3-(4-chlorophenyl)-2H-1-benzopyran-2-one 0
                                                4-ethyl-7-hydroxy-3-(p-methoxyphenyl)coumarin 0
                                                5,6,7-trimethoxycoumarin 0
                                                6,8-difluoro-4-methylumbelliferyl phosphate 0
                                                6,8-difluoro-4-methylumbelliferyl phosphate (2-) 0
                                                7-[(6-hydroxy-2,5,5,8a-tetramethyl-4-oxo-1,4,4a,5,6,7,8,8a-octahydro-1-naphthalenyl)methoxy]-2H-chromen-2-one 0
                                                7-hydroxy-3-(4-methoxyphenyl)-4-methylcoumarin 0
                                                7-hydroxy-3-(4-methoxyphenyl)-4-propyl-2H-1-benzopyran-2-one 0
                                                7-methoxycoumarin-4-acetic acid 0
                                                daphnoretin 0
                                                licoarylcoumarin 0
paths to the root

Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.