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ONTOLOGY REPORT - ANNOTATIONS


Term:zinc protoporphyrin
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Accession:CHEBI:28783 term browser browse the term
Definition:A metalloprotoporphyrin that has formula C34H32N4O4Zn.
Synonyms:exact_synonym: (protoporphyrinato)zinc(II)
 related_synonym: (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)zinc(II);   Formula=C34H32N4O4Zn;   InChI=1S/C34H34N4O4.Zn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;   InChIKey=FUTVBRXUIKZACV-RGGAHWMASA-L;   PROTOPORPHYRIN IX CONTAINING ZN;   SMILES=CC1=C(CCC(O)=O)C2=[N]3C1=Cc1c(C)c(C=C)c4C=C5C(C)=C(C=C)C6=[N]5[Zn]3(n14)n1c(=C6)c(C)c(CCC(O)=O)c1=C2;   ZPP;   Zinc protoporphyrin-9;   Zn(ppIX);   zinc-protoporphyrin IX
 alt_id: CHEBI:10114;   CHEBI:27366
 xref: Beilstein:4932319 "Beilstein";   Beilstein:8184206 "Beilstein";   CAS:15442-64-5 "ChemIDplus";   CAS:15442-64-5 "KEGG COMPOUND";   DrugBank:DB03934;   Gmelin:403138 "Gmelin";   KEGG:C03184
 xref_mesh: MESH:C017803
 xref: PDBeChem:ZNH


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zinc protoporphyrin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Alad aminolevulinate, delta-, dehydratase JBrowse link 4 62,505,984 62,520,063 RGD:6480464
G Alb albumin JBrowse link 5 90,460,870 90,476,602 RGD:6480464
G Alms1 ALMS1, centrosome and basal body associated JBrowse link 6 85,587,498 85,726,611 RGD:6480464
G Ap2a1 adaptor-related protein complex 2, alpha 1 subunit JBrowse link 7 44,900,373 44,929,490 RGD:6480464
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit JBrowse link 10 80,706,956 80,742,303 RGD:6480464
G Asf1a anti-silencing function 1A histone chaperone JBrowse link 10 53,596,961 53,609,225 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 9 7,847,468 7,873,205 RGD:6480464
G Calca calcitonin/calcitonin-related polypeptide, alpha JBrowse link 7 114,625,981 114,636,910 RGD:6480464
G Cand1 cullin associated and neddylation disassociated 1 JBrowse link 10 119,198,812 119,240,055 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Ccdc6 coiled-coil domain containing 6 JBrowse link 10 70,096,878 70,193,200 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Cdk13 cyclin-dependent kinase 13 JBrowse link 13 17,711,676 17,805,212 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Chd7 chromodomain helicase DNA binding protein 7 JBrowse link 4 8,690,402 8,868,449 RGD:6480464
G Cmbl carboxymethylenebutenolidase-like (Pseudomonas) JBrowse link 15 31,565,342 31,590,119 RGD:6480464
G Cxcl1 chemokine (C-X-C motif) ligand 1 JBrowse link 5 90,891,245 90,893,121 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 JBrowse link 5 92,346,638 92,348,889 RGD:6480464
G Cxcl2 chemokine (C-X-C motif) ligand 2 JBrowse link 5 90,903,899 90,905,938 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 JBrowse link 7 26,835,339 26,843,264 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 7 140,763,819 140,774,990 RGD:6480464
G Dcun1d1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) JBrowse link 3 35,892,105 35,937,472 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Dhx29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 JBrowse link 13 112,927,680 112,969,432 RGD:6480464
G Dusp10 dual specificity phosphatase 10 JBrowse link 1 184,034,381 184,075,636 RGD:6480464
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 6 70,844,484 70,905,241 RGD:6480464
G Eml4 echinoderm microtubule associated protein like 4 JBrowse link 17 83,350,891 83,480,361 RGD:6480464
G F2 coagulation factor II JBrowse link 2 91,612,397 91,636,457 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,518,759 25,575,718 RGD:6480464
G Flt1 FMS-like tyrosine kinase 1 JBrowse link 5 147,561,604 147,726,438 RGD:6480464
G Fos FBJ osteosarcoma oncogene JBrowse link 12 85,473,890 85,477,274 RGD:6480464
G Fut4 fucosyltransferase 4 JBrowse link 9 14,748,459 14,752,122 RGD:6480464
G Glul glutamate-ammonia ligase (glutamine synthetase) JBrowse link 1 153,899,929 153,909,723 RGD:6480464
G Gm9920 predicted gene 9920 JBrowse link 15 55,099,917 55,113,582 RGD:6480464
G Gpr132 G protein-coupled receptor 132 JBrowse link 12 112,850,873 112,868,416 RGD:6480464
G Gucy1a1 guanylate cyclase 1, soluble, alpha 1 JBrowse link 3 82,092,427 82,145,946 RGD:6480464
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 JBrowse link 3 82,032,004 82,074,711 RGD:6480464
G Haus2 HAUS augmin-like complex, subunit 2 JBrowse link 2 120,609,382 120,621,560 RGD:6480464
G Hfe homeostatic iron regulator JBrowse link 13 23,702,034 23,710,854 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 5 149,046,702 149,053,057 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hmox2 heme oxygenase 2 JBrowse link 16 4,726,361 4,766,741 RGD:6480464
G Hp1bp3 heterochromatin protein 1, binding protein 3 JBrowse link 4 138,216,470 138,244,683 RGD:6480464
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 1 193,221,640 193,264,049 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Ifnb1 interferon beta 1, fibroblast JBrowse link 4 88,522,025 88,522,794 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il18 interleukin 18 JBrowse link 9 50,554,700 50,581,841 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 1 87,620,312 87,720,510 RGD:6480464
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 74,013,914 74,023,921 RGD:6480464
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 10 120,141,648 120,202,130 RGD:6480464
G Itgam integrin alpha M JBrowse link 7 128,062,640 128,118,491 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 JBrowse link 3 64,949,212 65,378,225 RGD:6480464
G Kctd20 potassium channel tetramerisation domain containing 20 JBrowse link 17 28,952,436 28,969,549 RGD:6480464
G Kidins220 kinase D-interacting substrate 220 JBrowse link 12 24,974,903 25,063,152 RGD:6480464
G Kitl kit ligand JBrowse link 10 100,015,615 100,100,416 RGD:6480464
G Kras Kirsten rat sarcoma viral oncogene homolog JBrowse link 6 145,216,699 145,250,420 RGD:6480464
G Larp1b La ribonucleoprotein domain family, member 1B JBrowse link 3 40,949,770 41,040,207 RGD:6480464
G Lnx1 ligand of numb-protein X 1 JBrowse link 5 74,592,447 74,703,043 RGD:6480464
G Lyrm7 LYR motif containing 7 JBrowse link 11 54,826,866 54,860,921 RGD:6480464
G Macf1 microtubule-actin crosslinking factor 1 JBrowse link 4 123,349,633 123,687,802 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mark2 MAP/microtubule affinity regulating kinase 2 JBrowse link 19 7,275,396 7,341,860 RGD:6480464
G Mfn1 mitofusin 1 JBrowse link 3 32,529,443 32,579,225 RGD:6480464
G Mllt3 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 JBrowse link 4 87,769,925 88,033,407 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:6480464
G Myd88 myeloid differentiation primary response gene 88 JBrowse link 9 119,335,934 119,340,018 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 5 134,220,053 134,229,628 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nos1 nitric oxide synthase 1, neuronal JBrowse link 5 117,866,839 117,958,840 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Pde4dip phosphodiesterase 4D interacting protein (myomegalin) JBrowse link 3 97,689,828 97,888,707 RGD:6480464
G Pgf placental growth factor JBrowse link 12 85,166,637 85,177,785 RGD:6480464
G Polr3k polymerase (RNA) III (DNA directed) polypeptide K JBrowse link 2 181,864,360 181,870,830 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Ppil1 peptidylprolyl isomerase (cyclophilin)-like 1 JBrowse link 17 29,250,835 29,263,971 RGD:6480464
G Prdx2 peroxiredoxin 2 JBrowse link 8 84,969,622 84,974,811 RGD:6480464
G Prr11 proline rich 11 JBrowse link 11 87,089,156 87,108,714 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 JBrowse link 5 20,986,645 21,055,911 RGD:6480464
G Ptpro protein tyrosine phosphatase, receptor type, O JBrowse link 6 137,252,299 137,464,634 RGD:6480464
G Rap2c RAP2C, member of RAS oncogene family JBrowse link X 51,003,912 51,020,091 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Rgcc regulator of cell cycle JBrowse link 14 79,288,750 79,301,635 RGD:6480464
G Rsph10b radial spoke head 10 homolog B (Chlamydomonas) JBrowse link 5 143,933,107 143,985,719 RGD:6480464
G Scaf11 SR-related CTD-associated factor 11 JBrowse link 15 96,411,698 96,460,988 RGD:6480464
G Scamp1 secretory carrier membrane protein 1 JBrowse link 13 94,201,310 94,285,831 RGD:6480464
G Sec23b SEC23 homolog B, COPII coat complex component JBrowse link 2 144,556,229 144,590,753 RGD:6480464
G Sel1l sel-1 suppressor of lin-12-like (C. elegans) JBrowse link 12 91,806,043 91,849,157 RGD:6480464
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 JBrowse link 17 12,419,972 12,507,704 RGD:6480464
G Slc35e1 solute carrier family 35, member E1 JBrowse link 8 72,477,995 72,492,614 RGD:6480464
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) JBrowse link 11 60,777,525 60,788,287 RGD:6480464
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:6480464
G Sptbn1 spectrin beta, non-erythrocytic 1 JBrowse link 11 30,099,395 30,268,384 RGD:6480464
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:6480464
G Ssbp3 single-stranded DNA binding protein 3 JBrowse link 4 106,911,470 107,049,694 RGD:6480464
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 JBrowse link 15 67,102,875 67,176,946 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 1 52,119,438 52,161,865 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 11 100,886,806 100,939,594 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Timp1 tissue inhibitor of metalloproteinase 1 JBrowse link X 20,870,166 20,874,737 RGD:6480464
G Tlr2 toll-like receptor 2 JBrowse link 3 83,836,272 83,841,824 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a JBrowse link 6 125,349,723 125,362,483 RGD:6480464
G Tnrc6a trinucleotide repeat containing 6a JBrowse link 7 123,031,101 123,195,296 RGD:6480464
G Tollip toll interacting protein JBrowse link 7 141,881,580 141,902,461 RGD:6480464
G Traf6 TNF receptor-associated factor 6 JBrowse link 2 101,678,420 101,701,668 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Ubxn2a UBX domain protein 2A JBrowse link 12 4,876,979 4,907,716 RGD:6480464
G Usp13 ubiquitin specific peptidase 13 (isopeptidase T-3) JBrowse link 3 32,816,283 32,938,075 RGD:6480464
G Usp34 ubiquitin specific peptidase 34 JBrowse link 11 23,303,185 23,490,560 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:6480464
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor JBrowse link 15 97,854,427 97,908,296 RGD:6480464
G Vps33a VPS33A CORVET/HOPS core subunit JBrowse link 5 123,528,757 123,573,043 RGD:6480464
G Wsb2 WD repeat and SOCS box-containing 2 JBrowse link 5 117,357,305 117,378,601 RGD:6480464
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:6480464
G Zfp827 zinc finger protein 827 JBrowse link 8 79,027,486 79,193,768 RGD:6480464
G Zfyve16 zinc finger, FYVE domain containing 16 JBrowse link 13 92,487,749 92,530,810 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21021
    role 21002
      biological role 21000
        biochemical role 19962
          cofactor 15667
            porphyrins 336
              metalloporphyrin 310
                metalloprotoporphyrin 310
                  zinc protoporphyrin 142
Path 2
Term Annotations click to browse term
  CHEBI ontology 21021
    subatomic particle 21015
      composite particle 21015
        hadron 21015
          baryon 21015
            nucleon 21015
              atomic nucleus 21015
                atom 21015
                  main group element atom 20858
                    p-block element atom 20858
                      carbon group element atom 20599
                        carbon atom 20576
                          organic molecular entity 20576
                            organic molecule 20430
                              organic cyclic compound 20115
                                organic heterocyclic compound 18975
                                  organonitrogen heterocyclic compound 17433
                                    polypyrrole 602
                                      tetrapyrrole 490
                                        cyclic tetrapyrrole 355
                                          porphyrins 336
                                            metalloporphyrin 310
                                              metalloprotoporphyrin 310
                                                zinc protoporphyrin 142
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.