|
G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
[2,2-bis(4-glycidyloxyphenyl)propane co-treated with Hesperidin] inhibits the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of ACHE protein]; Hesperidin inhibits the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of ACHE protein] |
CTD |
PMID:32627286 |
|
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
|
|
G |
Afp |
alpha-fetoprotein |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein]; Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] |
CTD |
PMID:28935427 PMID:30779474 |
|
NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:30779474 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Alb |
albumin |
multiple interactions increases expression |
ISO |
[Hesperidin co-treated with Doxorubicin] results in increased expression of ALB protein Hesperidin results in increased expression of ALB protein |
CTD |
PMID:29481770 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein] Doxorubicin promotes the reaction [Hesperidin results in increased expression of BAX mRNA] |
CTD |
PMID:24954035 PMID:29481770 PMID:32050098 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Hesperidin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein] Hesperidin results in decreased expression of BCL2 mRNA Doxorubicin promotes the reaction [Hesperidin results in decreased expression of BCL2 mRNA] |
CTD |
PMID:22093918 PMID:24954035 PMID:29481770 PMID:30623541 PMID:32050098 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
EXP |
Hesperidin results in increased expression of BMP2 mRNA |
CTD |
PMID:21820093 |
|
NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression |
EXP ISO |
Hesperidin inhibits the reaction [Acetaminophen results in increased expression of CASP3 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of CASP3 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Hesperidin promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 protein] [Hesperidin co-treated with Doxorubicin] results in increased activity of CASP3 protein; Doxorubicin promotes the reaction [Hesperidin results in increased expression of CASP3 mRNA] Hesperidin results in increased activity of CASP3 protein |
CTD |
PMID:22093918 PMID:29481770 PMID:30623541 PMID:30779474 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Acetaminophen results in increased expression of CASP9 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of CASP9 protein] |
CTD |
PMID:22093918 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cat |
catalase |
multiple interactions increases activity |
EXP ISO |
Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Acetic Acid results in increased activity of CAT protein]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CAT protein]; Hesperidin inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of CAT protein] Hesperidin results in increased activity of CAT protein Hesperidin inhibits the reaction [Doxorubicin results in increased activity of CAT protein] |
CTD |
PMID:22093918 PMID:29481770 PMID:30098279 PMID:30623541 PMID:30779474 PMID:31095933 PMID:32050098 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of CCL3 protein]; Hesperidin inhibits the reaction [Ethanol results in increased expression of CCL3 protein] |
CTD |
PMID:30368987 PMID:30811821 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
|
|
G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 protein] |
CTD |
PMID:30779474 |
|
NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
Hesperidin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein] |
CTD |
PMID:17400256 |
|
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
|
|
G |
Fabp9 |
fatty acid binding protein 9 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in increased secretion of FABP9 protein] |
CTD |
PMID:32050098 |
|
NCBI chr 2:93,803,503...93,807,069
Ensembl chr 2:93,803,449...93,807,069
|
|
G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the activity of FASN protein] |
CTD |
PMID:16427799 |
|
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
decreases activity multiple interactions |
ISO |
Hesperidin results in decreased activity of G6PD protein Hesperidin affects the reaction [LEPR protein affects the activity of G6PD protein] |
CTD |
PMID:16427799 PMID:25130191 |
|
NCBI chr X:156,274,800...156,293,935
Ensembl chr X:156,274,800...156,293,926
|
|
G |
Gck |
glucokinase |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the expression of GCK mRNA] |
CTD |
PMID:16427799 |
|
NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
decreases activity multiple interactions |
ISO EXP |
Hesperidin results in decreased activity of GPT protein Hesperidin inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein] [Doxorubicin co-treated with Hesperidin] results in decreased activity of GPT protein |
CTD |
PMID:29481770 PMID:30779474 |
|
NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of GSR protein]; Hesperidin inhibits the reaction [Acetaminophen results in decreased activity of GSR protein] |
CTD |
PMID:22093918 PMID:30098279 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased secretion of HAVCR1 protein]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein] |
CTD |
PMID:22093918 PMID:30098279 |
|
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the activity of HMGCR protein] |
CTD |
PMID:16427799 |
|
NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of HMOX1 protein]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 protein] |
CTD |
PMID:28935427 PMID:32050098 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 protein] |
CTD |
PMID:32050098 |
|
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Hesperidin inhibits the reaction [Glucose results in increased expression of ICAM1]; Hesperidin inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; Hesperidin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:17400256 PMID:22074828 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Hesperidin inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; Hesperidin inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Hesperidin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Hesperidin inhibits the reaction [TNF protein co-treated with and results in increased expression of IL1B protein co-treated with and results in increased expression of CXCL8 protein] Hesperidin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] |
CTD |
PMID:17400256 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
Hesperidin promotes the reaction [Lipopolysaccharides results in increased expression of IL4 protein] |
CTD |
PMID:17400256 |
|
NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
|
|
G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Hesperidin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Hesperidin results in decreased expression of IL6 protein [naringin co-treated with Hesperidin] results in decreased expression of IL6 protein; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein] |
CTD |
PMID:17400256 PMID:21820093 PMID:30623541 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Lep |
leptin |
decreases expression multiple interactions |
EXP |
Hesperidin results in decreased expression of LEP protein [naringin co-treated with Hesperidin] results in decreased expression of LEP protein |
CTD |
PMID:21820093 |
|
NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
|
|
G |
Lepr |
leptin receptor |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose]; Hesperidin affects the reaction [LEPR protein affects the activity of FASN protein]; Hesperidin affects the reaction [LEPR protein affects the activity of G6PD protein]; Hesperidin affects the reaction [LEPR protein affects the activity of HMGCR protein]; Hesperidin affects the reaction [LEPR protein affects the expression of GCK mRNA]; Hesperidin affects the reaction [LEPR protein affects the expression of PPARG protein]; Hesperidin affects the reaction [LEPR protein affects the expression of SLC2A2 protein]; Hesperidin affects the reaction [LEPR protein affects the expression of SLC2A4 protein] |
CTD |
PMID:16427799 |
|
NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:19110045 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:19110045 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
|
|
G |
Mir126b |
microRNA 126b |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MIR126B mRNA] |
CTD |
PMID:32050098 |
|
NCBI chr 3:4,042,488...4,042,560
|
|
G |
Mir181a2 |
microRNA 181a-2 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MIR181A2 mRNA] |
CTD |
PMID:32050098 |
|
NCBI chr 3:23,150,352...23,150,468
Ensembl chr 3:23,150,352...23,150,468
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases secretion |
ISO |
Hesperidin inhibits the reaction [Acetaldehyde results in increased expression of and results in increased activity of MMP9 protein]; Hesperidin inhibits the reaction [Acetaldehyde results in increased expression of MMP9 mRNA]; Hesperidin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA] Hesperidin results in decreased secretion of MMP9 protein |
CTD |
PMID:19110045 PMID:20138977 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
|
|
G |
Mpo |
myeloperoxidase |
multiple interactions decreases activity |
EXP |
Hesperidin inhibits the reaction [Acetic Acid results in increased activity of MPO protein] Hesperidin results in decreased activity of MPO protein |
CTD |
PMID:31095933 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
|
|
G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of NFE2L2 mRNA]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of NFE2L2 protein]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of NFE2L2 protein] |
CTD |
PMID:28935427 PMID:32050098 |
|
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Acetaminophen results in increased expression of NFKB1 mRNA] |
CTD |
PMID:22093918 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP ISO |
Hesperidin inhibits the reaction [Acetaminophen results in increased expression of NOS2 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of NOS2 protein] Hesperidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:12512693 PMID:22093918 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Ethanol results in increased activity of PARP1 protein] |
CTD |
PMID:30368987 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of PCNA protein] |
CTD |
PMID:28935427 |
|
NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
|
|
G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of PIK3R1 protein] |
CTD |
PMID:30779474 |
|
NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
EXP ISO |
Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG mRNA]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of PPARG protein] Hesperidin affects the reaction [LEPR protein affects the expression of PPARG protein] |
CTD |
PMID:16427799 PMID:24954035 PMID:28935427 PMID:30623541 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Dextran Sulfate results in decreased expression of PPARGC1A protein]; Hesperidin inhibits the reaction [Ethanol results in decreased expression of PPARGC1A protein] |
CTD |
PMID:30368987 PMID:30811821 |
|
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO EXP |
Hesperidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PTGS2 protein] Hesperidin inhibits the reaction [Acetaldehyde results in increased expression of PTGS2 mRNA] |
CTD |
PMID:16101151 PMID:19110045 PMID:30098279 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Isoproterenol results in increased expression of RELA protein] |
CTD |
PMID:30623541 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Sgpp2 |
sphingosine-1-phosphate phosphatase 2 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of SGPP2 mRNA] |
CTD |
PMID:30811821 |
|
NCBI chr 9:84,203,094...84,321,269
Ensembl chr 9:84,203,072...84,319,874
|
|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SIRT1 mRNA]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SIRT1 protein] |
CTD |
PMID:32050098 |
|
NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
|
|
G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the expression of SLC2A2 protein] |
CTD |
PMID:16427799 |
|
NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
|
|
G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
Hesperidin affects the reaction [LEPR protein affects the expression of SLC2A4 protein] |
CTD |
PMID:16427799 |
|
NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SOD2 mRNA]; Hesperidin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SOD2 protein] |
CTD |
PMID:32050098 |
|
NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
|
|
G |
Sphk1 |
sphingosine kinase 1 |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of SPHK1 protein] |
CTD |
PMID:30811821 |
|
NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
|
|
G |
Tfeb |
transcription factor EB |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Ethanol results in decreased expression of TFEB mRNA] |
CTD |
PMID:30368987 |
|
NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
|
|
G |
Tnc |
tenascin C |
multiple interactions |
EXP |
Hesperidin inhibits the reaction [Ethanol results in increased expression of TNC protein] |
CTD |
PMID:30368987 |
|
NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
Hesperidin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Hesperidin inhibits the reaction [TNF protein co-treated with and results in increased expression of IL1B protein co-treated with and results in increased expression of CXCL8 protein]; Hesperidin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Hesperidin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of TNF protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of TNF protein] Hesperidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
CTD |
PMID:17400256 PMID:28935427 PMID:30623541 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tnfrsf25 |
TNF receptor superfamily member 25 |
increases expression |
ISO |
Hesperidin results in increased expression of TNFRSF25 mRNA |
CTD |
PMID:24633329 |
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NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
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G |
Tradd |
TNFRSF1A-associated via death domain |
increases expression |
ISO |
Hesperidin results in increased expression of TRADD mRNA |
CTD |
PMID:24633329 |
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NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions decreases expression |
ISO |
Hesperidin inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Hesperidin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] Hesperidin results in decreased expression of VCAM1 |
CTD |
PMID:17400256 PMID:30991044 |
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NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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