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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4,6-trichlorophenol
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Accession:CHEBI:28755 term browser browse the term
Definition:A trichlorophenol with phenolic substituents on positions 2, 4 and 6.
Synonyms:related_synonym: 1,3,5-Trichloro-2-hydroxybenzene;   2,4,6-TCP;   Formula=C6H3Cl3O;   InChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H;   InChIKey=LINPIYWFGCPVIE-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)cc(Cl)cc1Cl
 alt_id: CHEBI:19334;   CHEBI:898
 xref: Beilstein:776729;   CAS:88-06-2;   Gmelin:3766;   KEGG:C07098
 xref_mesh: MESH:C024564
 xref: MetaCyc:TRICHLOROPHENOL;   PDBeChem:T6C;   PMID:21863115;   PMID:22748215;   PMID:23995979;   PMID:24078273;   Reaxys:776729;   UM-BBD_compID:c0330;   Wikipedia:2\,4\,6-Trichlorophenol
 cyclic_relationship: is_conjugate_acid_of CHEBI:140426


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2,4,6-trichlorophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP11A1 mRNA CTD PMID:21296122 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP19A1 mRNA CTD PMID:21296122 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD17B4 mRNA CTD PMID:21296122 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD3B1 mRNA CTD PMID:21296122 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO 2,4,6-trichlorophenol binds to PPARG protein CTD PMID:25314719 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [alitretinoin binds to and results in increased activity of RXRB protein] CTD PMID:27565853 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of STAR mRNA CTD PMID:21296122 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [Triiodothyronine binds to THRB protein] CTD PMID:29409039 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link

Term paths to the root
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  CHEBI ontology 19821
    role 19769
      biological role 19769
        aetiopathogenetic role 19044
          carcinogenic agent 18365
            2,4,6-trichlorophenol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                carbocyclic compound 18314
                                  benzenoid aromatic compound 17458
                                    benzenes 17237
                                      chlorobenzenes 13603
                                        chlorophenol 1182
                                          trichlorophenols 18
                                            trichlorophenol 18
                                              2,4,6-trichlorophenol 8
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