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ONTOLOGY REPORT - ANNOTATIONS


Term:thromboxane B2
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Accession:CHEBI:28728 term browser browse the term
Definition:A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
Synonyms:exact_synonym: (5Z,13E,15S)-9alpha,11,15-trihydroxythromboxa-5,13-dien-1-oic acid
 related_synonym: Formula=C20H34O6;   InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1;   InChIKey=XNRNNGPBEPRNAR-JQBLCGNGSA-N;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1OC(O)C[C@H](O)[C@@H]1C\\C=C/CCCC(O)=O;   TXB2
 alt_id: CHEBI:26994;   CHEBI:9576
 xref: CAS:54397-85-2 "ChemIDplus";   CAS:54397-85-2 "KEGG COMPOUND";   HMDB:HMDB0003252;   KEGG:C05963;   LIPID_MAPS_instance:LMFA03030002 "LIPID MAPS"
 xref_mesh: MESH:D013929
 xref: PMID:24433337 "Europe PMC";   PMID:24786190 "Europe PMC";   PMID:7847191 "Europe PMC";   Reaxys:1399489 "Reaxys";   Wikipedia:Thromboxane_B2
 cyclic_relationship: is_conjugate_acid_of CHEBI:90696


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thromboxane B2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
11-dehydro-thromboxane B2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        biochemical role 19125
          metabolite 19093
            eukaryotic metabolite 18735
              animal metabolite 18475
                mammalian metabolite 18457
                  mouse metabolite 17874
                    thromboxane B2 9
                      11-dehydro-thromboxane B2 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        monocarboxylic acid 17245
                                          fatty acid 15807
                                            fatty acid derivative 1008
                                              icosanoid 450
                                                prostanoid 393
                                                  thromboxane 14
                                                    thromboxanes B 9
                                                      thromboxane B2 9
                                                        11-dehydro-thromboxane B2 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.