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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eriocitrin
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Accession:CHEBI:28709 term browser browse the term
Definition:A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Synonyms:exact_synonym: (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
 related_synonym: Eriodictioside;   Eriodictyol 7-O-rutinoside;   Formula=C27H32O15;   InChI=1S/C27H32O15/c1-9-20(32)22(34)24(36)26(39-9)38-8-18-21(33)23(35)25(37)27(42-18)40-11-5-14(30)19-15(31)7-16(41-17(19)6-11)10-2-3-12(28)13(29)4-10/h2-6,9,16,18,20-30,32-37H,7-8H2,1H3/t9-,16-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1;   InChIKey=OMQADRGFMLGFJF-MNPJBKLOSA-N;   SMILES=C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
 alt_id: CHEBI:23944;   CHEBI:4831
 xref: AGR:IND43874123;   Beilstein:1304401;   CAS:13463-28-0;   KEGG:C09732;   KNApSAcK:C00008295;   LIPID_MAPS_instance:LMPK12140366
 xref_mesh: MESH:C114706
 xref: PMID:12551749;   PMID:15315375;   PMID:17690486;   PMID:9688172;   Reaxys:7846058



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eriocitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO eriocitrin results in increased expression of BAX protein CTD PMID:34724282 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO eriocitrin results in decreased expression of BCL2 protein CTD PMID:34724282 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp7 caspase 7 increases expression ISO eriocitrin results in increased expression of CASP7 protein CTD PMID:34724282 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 increases expression ISO eriocitrin results in increased expression of CASP9 protein CTD PMID:34724282 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO eriocitrin results in decreased expression of CCND1 protein CTD PMID:34724282 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO eriocitrin results in decreased phosphorylation of JAK2 protein CTD PMID:34724282 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [eriocitrin results in increased phosphorylation of MAPK8 protein] CTD PMID:34724282 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO eriocitrin results in decreased expression of PCNA protein CTD PMID:34724282 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases phosphorylation ISO eriocitrin results in decreased phosphorylation of SRC protein CTD PMID:34724282 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO eriocitrin results in decreased phosphorylation of STAT3 protein CTD PMID:34724282 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20024
      chemical role 19563
        antioxidant 15693
          eriocitrin 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            organic molecule 19835
                              organic cyclic compound 19589
                                organic heterocyclic compound 18857
                                  oxacycle 17704
                                    benzopyran 11225
                                      1-benzopyran 10962
                                        flavonoid 6580
                                          flavans 3072
                                            flavanones 338
                                              hydroxyflavanone 324
                                                tetrahydroxyflavanone 54
                                                  eriodictyol 48
                                                    eriocitrin 10
paths to the root