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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:21-deoxycortisol
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Accession:CHEBI:28697 term browser browse the term
Definition:A deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency.
Synonyms:exact_synonym: 11beta,17-dihydroxypregn-4-ene-3,20-dione
 related_synonym: (1R,3aS,3bS,9aR,9bS,10S,11aS)-1-acetyl-1,10-dihydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one;   11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione;   11beta,17-dihydroxyprogesterone;   11beta,17alpha-dihydroxypregn-4-ene-3,20-dione;   11beta,17alpha-dihydroxyprogesterone;   4-pregnene-11beta,17alpha-diol-3,20-dione;   Formula=C21H30O4;   InChI=1S/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16-,17-,18+,19-,20-,21-/m0/s1;   InChIKey=LCZBQMKVFQNSJR-UJPCIWJBSA-N;   SMILES=C1C(C=C2[C@](C1)([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@](CC4)(C(C)=O)O)C)[H])[H])[H])C)=O;   pregn-4-ene-11beta,17alpha-diol-3,20-dione
 alt_id: CHEBI:1297;   CHEBI:19801
 xref: CAS:641-77-0;   FooDB:FDB023283;   HMDB:HMDB0004030;   KEGG:C05497;   LIPID_MAPS_instance:LMST02030195;   PMID:10731638;   PMID:16551734;   PMID:17456574;   PMID:2531882;   PMID:2555382;   PMID:2614011;   PMID:2827419;   PMID:28499151;   PMID:28610588;   PMID:28774496;   PMID:2986404;   PMID:31450227;   PMID:3258316;   PMID:4372245;   PMID:6310249;   PMID:8055790;   PMID:845476;   PMID:8753277;   Wikipedia:21-Deoxycortisol



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Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    role 5044
      application 863
        anti-inflammatory agent 71
          anti-inflammatory drug 50
            cortisol 2
              deoxycortisol 0
                21-deoxycortisol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5052
    subatomic particle 5043
      composite particle 5043
        hadron 5071
          baryon 5043
            nucleon 5043
              atomic nucleus 5043
                atom 5043
                  main group element atom 5013
                    p-block element atom 5010
                      carbon group element atom 4927
                        carbon atom 4954
                          organic molecular entity 4926
                            heteroorganic entity 4768
                              organochalcogen compound 4730
                                organooxygen compound 4692
                                  carbonyl compound 4643
                                    ketone 4347
                                      oxyketone 4317
                                        alpha-oxyketone 4297
                                          alpha-hydroxy ketone 4297
                                            primary alpha-hydroxy ketone 17
                                              cortisol 2
                                                deoxycortisol 0
                                                  21-deoxycortisol 0
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