Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:21-deoxycortisol
go back to main search page
Accession:CHEBI:28697 term browser browse the term
Definition:A deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency.
Synonyms:exact_synonym: 11beta,17-dihydroxypregn-4-ene-3,20-dione
 related_synonym: (1R,3aS,3bS,9aR,9bS,10S,11aS)-1-acetyl-1,10-dihydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one;   11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione;   11beta,17-dihydroxyprogesterone;   11beta,17alpha-dihydroxypregn-4-ene-3,20-dione;   11beta,17alpha-dihydroxyprogesterone;   4-pregnene-11beta,17alpha-diol-3,20-dione;   Formula=C21H30O4;   InChI=1S/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16-,17-,18+,19-,20-,21-/m0/s1;   InChIKey=LCZBQMKVFQNSJR-UJPCIWJBSA-N;   SMILES=C1C(C=C2[C@](C1)([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@](CC4)(C(C)=O)O)C)[H])[H])[H])C)=O;   pregn-4-ene-11beta,17alpha-diol-3,20-dione
 alt_id: CHEBI:1297;   CHEBI:19801
 xref: CAS:641-77-0;   FooDB:FDB023283;   HMDB:HMDB0004030;   KEGG:C05497;   LIPID_MAPS_instance:LMST02030195;   PMID:10731638;   PMID:16551734;   PMID:17456574;   PMID:2531882;   PMID:2555382;   PMID:2614011;   PMID:2827419;   PMID:28499151;   PMID:28610588;   PMID:28774496;   PMID:2986404;   PMID:31450227;   PMID:3258316;   PMID:4372245;   PMID:6310249;   PMID:8055790;   PMID:845476;   PMID:8753277;   Wikipedia:21-Deoxycortisol


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        anti-inflammatory agent 14958
          anti-inflammatory drug 13610
            cortisol 154
              deoxycortisol 5
                21-deoxycortisol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      ketone 15948
                                        oxyketone 8487
                                          alpha-oxyketone 8487
                                            alpha-hydroxy ketone 8487
                                              primary alpha-hydroxy ketone 7450
                                                cortisol 154
                                                  deoxycortisol 5
                                                    21-deoxycortisol 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.