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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose
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Accession:CHEBI:28645 term browser browse the term
Definition:A D-fructofuranose that has formula C6H12O6.
Synonyms:related_synonym: FRUCTOSE;   Formula=C6H12O6;   InChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1;   InChIKey=RFSUNEUAIZKAJO-ARQDHWQXSA-N;   SMILES=OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O;   beta-D-Fructose;   beta-D-arabino-Hexulose;   beta-Fruit sugar;   beta-Levulose
 alt_id: CHEBI:10373;   CHEBI:22766;   CHEBI:42560
 xref: Beilstein:1680732;   CAS:53188-23-1;   KEGG:C02336;   KNApSAcK:C00001117;   PDBeChem:FRU
 cyclic_relationship: is_enantiomer_of CHEBI:43703


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beta-D-fructofuranose 1,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22227475 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22227475 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases degradation
ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
fructose-1,6-diphosphate results in decreased degradation of NOS2 mRNA
CTD PMID:22227475 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
beta-D-fructofuranose 2,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkm phosphofructokinase, muscle multiple interactions ISO fructose 2,6-diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            fundamental metabolite 12766
              fructose 307
                D-fructose 15
                  D-fructofuranose 6
                    beta-D-fructofuranose 6
                      agrocinopine B 0
                      beta-D-fructofuranose 1,6-bisphosphate 5
                      beta-D-fructofuranose 1,6-bisphosphate(4-) 0
                      beta-D-fructofuranose 2,6-bisphosphate 1
                      beta-D-fructofuranose 2-phosphate 0
                      beta-D-fructofuranose 6-phosphate 0
                      beta-D-fructofuranose 6-phosphate(2-) 0
                      beta-D-fructuronic acid 0
                      bis-beta-D-fructofuranose 1,2':2,3'-dianhydride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            heteroorganic entity 19283
                              organochalcogen compound 19054
                                organooxygen compound 19004
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      monosaccharide 4298
                                        hexose 2421
                                          ketohexose 371
                                            fructose 307
                                              D-fructose 15
                                                D-fructofuranose 6
                                                  beta-D-fructofuranose 6
                                                    agrocinopine B 0
                                                    beta-D-fructofuranose 1,6-bisphosphate 5
                                                    beta-D-fructofuranose 1,6-bisphosphate(4-) 0
                                                    beta-D-fructofuranose 2,6-bisphosphate 1
                                                    beta-D-fructofuranose 2-phosphate 0
                                                    beta-D-fructofuranose 6-phosphate 0
                                                    beta-D-fructofuranose 6-phosphate(2-) 0
                                                    beta-D-fructuronic acid 0
                                                    bis-beta-D-fructofuranose 1,2':2,3'-dianhydride 0
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