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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose
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Accession:CHEBI:28645 term browser browse the term
Definition:A D-fructofuranose that has formula C6H12O6.
Synonyms:related_synonym: FRUCTOSE;   Formula=C6H12O6;   InChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1;   InChIKey=RFSUNEUAIZKAJO-ARQDHWQXSA-N;   SMILES=OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O;   beta-D-Fructose;   beta-D-arabino-Hexulose;   beta-Fruit sugar;   beta-Levulose
 alt_id: CHEBI:10373;   CHEBI:22766;   CHEBI:42560
 xref: Beilstein:1680732;   CAS:53188-23-1;   KEGG:C02336;   KNApSAcK:C00001117;   PDBeChem:FRU
 cyclic_relationship: is_enantiomer_of CHEBI:43703



show annotations for term's descendants           Sort by:
beta-D-fructofuranose 1,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A multiple interactions ISO cylindrospermopsin results in increased expression of [ALDOA protein binds to fructose-1,6-diphosphate] CTD PMID:27494769 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO fructose-1,6-diphosphate results in increased expression of BAX protein CTD PMID:33078453 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22227475 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22227475 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases degradation
ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
fructose-1,6-diphosphate results in decreased degradation of NOS2 mRNA
CTD PMID:22227475 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Tp53 tumor protein p53 increases expression ISO fructose-1,6-diphosphate results in increased expression of TP53 protein CTD PMID:33078453 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
beta-D-fructofuranose 2,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbp1 fructose-bisphosphatase 1 decreases activity ISO fructose 2,6-diphosphate results in decreased activity of FBP1 protein CTD PMID:31974165 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases abundance ISO PFKFB1 gene mutant form results in decreased abundance of fructose 2,6-diphosphate CTD PMID:31974165 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO fructose 2,6-diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      biological role 19830
        biochemical role 19538
          metabolite 19525
            fundamental metabolite 14447
              fructose 931
                D-fructose 29
                  D-fructofuranose 11
                    beta-D-fructofuranose 11
                      agrocinopine B 0
                      alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride 0
                      beta-D-fructofuranose 1,6-bisphosphate 8
                      beta-D-fructofuranose 1,6-bisphosphate(4-) 0
                      beta-D-fructofuranose 2,6-bisphosphate 3
                      beta-D-fructofuranose 2-phosphate 0
                      beta-D-fructofuranose 6-phosphate 0
                      beta-D-fructofuranose 6-phosphate(2-) 0
                      beta-D-fructuronic acid 0
                      bis-beta-D-fructofuranose 1,2':2,3'-dianhydride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbohydrates and carbohydrate derivatives 15291
                                    carbohydrate 15291
                                      monosaccharide 4811
                                        hexose 2997
                                          ketohexose 991
                                            fructose 931
                                              D-fructose 29
                                                D-fructofuranose 11
                                                  beta-D-fructofuranose 11
                                                    agrocinopine B 0
                                                    alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride 0
                                                    beta-D-fructofuranose 1,6-bisphosphate 8
                                                    beta-D-fructofuranose 1,6-bisphosphate(4-) 0
                                                    beta-D-fructofuranose 2,6-bisphosphate 3
                                                    beta-D-fructofuranose 2-phosphate 0
                                                    beta-D-fructofuranose 6-phosphate 0
                                                    beta-D-fructofuranose 6-phosphate(2-) 0
                                                    beta-D-fructuronic acid 0
                                                    bis-beta-D-fructofuranose 1,2':2,3'-dianhydride 0
paths to the root