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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose 2,6-bisphosphate
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Accession:CHEBI:28602 term browser browse the term
Definition:A D-fructofuranose 2,6-bisphosphate with a beta-configuration at the anomeric centre.
Synonyms:exact_synonym: beta-D-fructofuranose 2,6-bis(dihydrogen phosphate)
 related_synonym: 2,6-di-O-phosphono-beta-D-fructofuranose;   D-Fructose 2,6-bisphosphate;   Formula=C6H14O12P2;   InChI=1S/C6H14O12P2/c7-2-6(18-20(13,14)15)5(9)4(8)3(17-6)1-16-19(10,11)12/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6+/m1/s1;   InChIKey=YXWOAJXNVLXPMU-ZXXMMSQZSA-N;   SMILES=OC[C@]1(O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O)OP(O)(O)=O
 alt_id: CHEBI:12351;   CHEBI:20933;   CHEBI:4122;   CHEBI:42586
 xref: CAS:79082-92-1;   HMDB:HMDB0001047;   KEGG:C00665;   KNApSAcK:C00007441
 xref_mesh: MESH:C027652
 xref: PDBeChem:FDP;   Reaxys:15436010;   Wikipedia:Fructose_2\,6-bisphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:58579

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beta-D-fructofuranose 2,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbp1 fructose-bisphosphatase 1 decreases activity ISO fructose 2,6-diphosphate results in decreased activity of FBP1 protein CTD PMID:31974165 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases abundance ISO PFKFB1 gene mutant form results in decreased abundance of fructose 2,6-diphosphate CTD PMID:31974165 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO fructose 2,6-diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link

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  CHEBI ontology 19844
    role 19820
      biological role 19818
        biochemical role 19525
          metabolite 19512
            eukaryotic metabolite 19334
              animal metabolite 19200
                mammalian metabolite 19199
                  mouse metabolite 18872
                    beta-D-fructofuranose 2,6-bisphosphate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      chalcogen 19548
                        oxygen atom 19491
                          oxygen molecular entity 19523
                            hydroxides 19331
                              oxoacid 18762
                                pnictogen oxoacid 14895
                                  phosphorus oxoacid 14485
                                    phosphoric acids 11416
                                      phosphoric acid 13924
                                        phosphoric acid derivative 13830
                                          phosphate 13829
                                            organic phosphate 13829
                                              carbohydrate phosphate 1862
                                                phospho sugar 1699
                                                  ketose phosphate 13
                                                    ketohexose phosphate 11
                                                      ketohexose bisphosphate 11
                                                        D-fructofuranose 2,6-bisphosphate 3
                                                          beta-D-fructofuranose 2,6-bisphosphate 3
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