CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: beta-D-fructofuranose 2,6-bisphosphate
Accession: CHEBI:28602
browse the term
Definition: A D-fructofuranose 2,6-bisphosphate with a beta-configuration at the anomeric centre.
Synonyms: exact_synonym: beta-D-fructofuranose 2,6-bis(dihydrogen phosphate)
related_synonym: 2,6-di-O-phosphono-beta-D-fructofuranose; D-Fructose 2,6-bisphosphate; Formula=C6H14O12P2; InChI=1S/C6H14O12P2/c7-2-6(18-20(13,14)15)5(9)4(8)3(17-6)1-16-19(10,11)12/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6+/m1/s1; InChIKey=YXWOAJXNVLXPMU-ZXXMMSQZSA-N; SMILES=OC[C@]1(O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O)OP(O)(O)=O
alt_id: CHEBI:12351; CHEBI:20933; CHEBI:4122; CHEBI:42586
xref: CAS:79082-92-1; HMDB:HMDB0001047; KEGG:C00665; KNApSAcK:C00007441
xref_mesh: MESH:C027652
xref: PDBeChem:FDP; Reaxys:15436010; Wikipedia:Fructose_2\,6-bisphosphate
cyclic_relationship: is_conjugate_acid_of CHEBI:58579
G
Fbp1
fructose-bisphosphatase 1
decreases activity
ISO
fructose 2,6-diphosphate results in decreased activity of FBP1 protein
CTD
PMID:31974165
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
G
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
decreases abundance
ISO
PFKFB1 gene mutant form results in decreased abundance of fructose 2,6-diphosphate
CTD
PMID:31974165
NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182
G
Pfkm
phosphofructokinase, muscle
multiple interactions
ISO
fructose 2,6-diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein]
CTD
PMID:23454376
NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
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