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ONTOLOGY REPORT - ANNOTATIONS


Term:isovaleric acid
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Accession:CHEBI:28484 term browser browse the term
Definition:A C5, branched-chain saturated fatty acid.
Synonyms:related_synonym: 3-Methylbutanoic acid;   3-Methylbuttersaeure;   3-methyl-n-butyric acid;   3-methylbutyric acid;   Formula=C5H10O2;   InChI=1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7);   InChIKey=GWYFCOCPABKNJV-UHFFFAOYSA-N;   Isovalerate;   Isovaleriansaeure;   SMILES=CC(C)CC(O)=O;   beta-methylbutyric acid;   delphinic acid;   isobutylformic acid;   isopentanoic acid;   isopropylacetic acid;   isovalerianic acid
 alt_id: CHEBI:24930;   CHEBI:43426;   CHEBI:6069
 xref: Beilstein:1098522 "ChemIDplus";   CAS:503-74-2 "ChemIDplus";   CAS:503-74-2 "KEGG COMPOUND";   CAS:503-74-2 "NIST Chemistry WebBook";   DrugBank:DB03750;   Gmelin:101117 "Gmelin";   KEGG:C08262;   KNApSAcK:C00001189;   LIPID_MAPS_instance:LMFA01020181 "LIPID MAPS"
 xref_mesh: MESH:C008216
 xref: PDBeChem:IVA;   PMID:12743728 "Europe PMC";   PPDB:3129
 cyclic_relationship: is_conjugate_acid_of CHEBI:48942


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isovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepr leptin receptor JBrowse link 4 101,717,137 101,815,352 RGD:6480464
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 JBrowse link 1 88,055,411 88,220,002 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 1 88,200,611 88,220,002 RGD:6480464
3-hydroxyisovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Fbxo32 F-box protein 32 JBrowse link 15 58,175,879 58,214,892 RGD:6480464
G Usp16 ubiquitin specific peptidase 16 JBrowse link 16 87,454,985 87,483,515 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 9 44,067,021 44,095,627 RGD:6480464
G Usp28 ubiquitin specific peptidase 28 JBrowse link 9 48,985,319 49,042,517 RGD:6480464
fenvalerate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 11 105,967,948 105,989,964 RGD:6480464
G Ache acetylcholinesterase JBrowse link 5 137,288,247 137,294,466 RGD:6480464
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl JBrowse link 11 116,171,883 116,199,045 RGD:6480464
G Alpl alkaline phosphatase, liver/bone/kidney JBrowse link 4 137,741,731 137,796,384 RGD:6480464
G Ar androgen receptor JBrowse link X 98,148,757 98,323,218 RGD:6480464
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:6480464
G C3 complement component 3 JBrowse link 17 57,203,967 57,228,136 RGD:6480464
G Calm1 calmodulin 1 JBrowse link 12 100,199,435 100,209,824 RGD:6480464
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:6480464
G Cdk2 cyclin-dependent kinase 2 JBrowse link 10 128,697,938 128,705,051 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 8 93,166,072 93,197,804 RGD:6480464
G Ces2e carboxylesterase 2E JBrowse link 8 104,926,260 104,934,672 RGD:6480464
G Cnst consortin, connexin sorting protein JBrowse link 1 179,546,444 179,627,478 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 9 57,998,024 58,027,031 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 19 46,667,165 46,673,000 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 JBrowse link 7 26,307,192 26,315,088 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 JBrowse link 19 39,287,044 39,330,713 RGD:6480464
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 JBrowse link 19 39,389,556 39,463,103 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 JBrowse link 15 82,370,527 82,380,260 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 7 140,763,819 140,774,990 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B JBrowse link 4 115,411,624 115,439,034 RGD:6480464
G Ephx1 epoxide hydrolase 1, microsomal JBrowse link 1 180,989,556 181,017,569 RGD:6480464
G Ephx2 epoxide hydrolase 2, cytoplasmic JBrowse link 14 66,084,372 66,124,522 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Esr2 estrogen receptor 2 (beta) JBrowse link 12 76,120,419 76,177,259 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 10 42,181,845 42,276,839 RGD:6480464
G G6pdx glucose-6-phosphate dehydrogenase X-linked JBrowse link X 74,409,483 74,428,880 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 10 75,561,076 75,586,193 RGD:6480464
G Got1 glutamic-oxaloacetic transaminase 1, soluble JBrowse link 19 43,499,752 43,524,605 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) JBrowse link 3 80,681,450 80,804,227 RGD:6480464
G Gsr glutathione reductase JBrowse link 8 33,653,238 33,698,162 RGD:6480464
G Gulp1 GULP, engulfment adaptor PTB domain containing 1 JBrowse link 1 44,551,380 44,796,838 RGD:6480464
G Gusb glucuronidase, beta JBrowse link 5 129,989,011 130,003,049 RGD:6480464
G Hap1 huntingtin-associated protein 1 JBrowse link 11 100,347,327 100,356,982 RGD:6480464
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 11 101,077,968 101,081,188 RGD:6480464
G Id2 inhibitor of DNA binding 2 JBrowse link 12 25,093,799 25,096,092 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 7 142,650,768 142,666,816 RGD:6480464
G Itgb5 integrin beta 5 JBrowse link 16 33,829,665 33,949,338 RGD:6480464
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 JBrowse link 6 108,213,083 108,551,116 RGD:6480464
G Itpr3 inositol 1,4,5-triphosphate receptor 3 JBrowse link 17 27,057,002 27,122,223 RGD:6480464
G Kyat1 kynurenine aminotransferase 1 JBrowse link 2 30,185,124 30,206,295 RGD:6480464
G Kynu kynureninase JBrowse link 2 43,555,258 43,683,048 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 16,619,698 16,687,812 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 1 171,213,934 171,218,845 RGD:6480464
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 JBrowse link 8 76,898,083 77,245,012 RGD:6480464
G Pgr progesterone receptor JBrowse link 9 8,898,900 8,968,611 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 9 58,217,179 58,249,796 RGD:6480464
G Ptgfrn prostaglandin F2 receptor negative regulator JBrowse link 3 101,040,230 101,110,745 RGD:6480464
G Rxra retinoid X receptor alpha JBrowse link 2 27,676,445 27,763,319 RGD:6480464
G Ryr1 ryanodine receptor 1, skeletal muscle JBrowse link 7 29,003,340 29,125,179 RGD:6480464
G Scn10a sodium channel, voltage-gated, type X, alpha JBrowse link 9 119,608,456 119,719,322 RGD:6480464
G Scn1b sodium channel, voltage-gated, type I, beta JBrowse link 7 31,116,524 31,127,023 RGD:6480464
G Scn2a sodium channel, voltage-gated, type II, alpha JBrowse link 2 65,620,764 65,767,447 RGD:6480464
G Scn3a sodium channel, voltage-gated, type III, alpha JBrowse link 2 65,457,118 65,567,591 RGD:6480464
G Scn3b sodium channel, voltage-gated, type III, beta JBrowse link 9 40,269,216 40,291,618 RGD:6480464
G Slc38a1 solute carrier family 38, member 1 JBrowse link 15 96,571,418 96,643,438 RGD:6480464
G Slc38a2 solute carrier family 38, member 2 JBrowse link 15 96,687,392 96,699,728 RGD:6480464
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,762 90,226,333 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 8 25,808,474 25,815,982 RGD:6480464
G Tbx3 T-box 3 JBrowse link 5 119,670,534 119,684,724 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 17 31,161,395 31,165,060 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 11 98,740,776 98,769,006 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 14 17,659,225 18,040,097 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 15 98,770,712 98,778,206 RGD:6480464
flucythrinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 98,148,757 98,323,218 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20752
    role 20730
      biological role 20729
        biochemical role 19819
          metabolite 19742
            eukaryotic metabolite 19574
              plant metabolite 17451
                isovaleric acid 89
                  (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                  2,3-dihydroxy-3-methylbutanoic acid + 0
                  2-(4-chlorophenyl)-3-methylbutyric acid + 81
                  2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                  2-hydroxy-3-methylbutyric acid + 0
                  3-hydroxyisovaleric acid + 5
                  N-isovaleryl-L-alanine 0
                  O-isovalerylcarnitine + 0
                  ananolignan J 0
                  ethyl isovalerate 0
                  isovaleryl-CoA 0
                  neurolenin A 0
                  neurolenin B 0
                  neurolenin C 0
                  neurolenin D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20752
    subatomic particle 20745
      composite particle 20745
        hadron 20745
          baryon 20745
            nucleon 20745
              atomic nucleus 20745
                atom 20745
                  main group element atom 20665
                    p-block element atom 20665
                      carbon group element atom 20401
                        carbon atom 20377
                          organic molecular entity 20377
                            organic group 19045
                              organic divalent group 19034
                                organodiyl group 19034
                                  carbonyl group 19007
                                    carbonyl compound 19007
                                      carboxylic acid 18675
                                        monocarboxylic acid 17893
                                          fatty acid 16347
                                            short-chain fatty acid 16016
                                              fatty acid 4:0 7203
                                                butyric acid 5392
                                                  methylbutyric acid 985
                                                    isovaleric acid 89
                                                      (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                                                      2,3-dihydroxy-3-methylbutanoic acid + 0
                                                      2-(4-chlorophenyl)-3-methylbutyric acid + 81
                                                      2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                                                      2-hydroxy-3-methylbutyric acid + 0
                                                      3-hydroxyisovaleric acid + 5
                                                      N-isovaleryl-L-alanine 0
                                                      O-isovalerylcarnitine + 0
                                                      ananolignan J 0
                                                      ethyl isovalerate 0
                                                      isovaleryl-CoA 0
                                                      neurolenin A 0
                                                      neurolenin B 0
                                                      neurolenin C 0
                                                      neurolenin D 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.