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ONTOLOGY REPORT - ANNOTATIONS


Term:isovaleric acid
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Accession:CHEBI:28484 term browser browse the term
Definition:A C5, branched-chain saturated fatty acid.
Synonyms:related_synonym: 3-Methylbutanoic acid;   3-Methylbuttersaeure;   3-methyl-n-butyric acid;   3-methylbutyric acid;   Formula=C5H10O2;   InChI=1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7);   InChIKey=GWYFCOCPABKNJV-UHFFFAOYSA-N;   Isovalerate;   Isovaleriansaeure;   SMILES=CC(C)CC(O)=O;   beta-methylbutyric acid;   delphinic acid;   isobutylformic acid;   isopentanoic acid;   isopropylacetic acid;   isovalerianic acid
 alt_id: CHEBI:24930;   CHEBI:43426;   CHEBI:6069
 xref: Beilstein:1098522 "ChemIDplus";   CAS:503-74-2 "ChemIDplus";   CAS:503-74-2 "KEGG COMPOUND";   CAS:503-74-2 "NIST Chemistry WebBook";   DrugBank:DB03750;   Gmelin:101117 "Gmelin";   KEGG:C08262;   KNApSAcK:C00001189;   LIPID_MAPS_instance:LMFA01020181 "LIPID MAPS"
 xref_mesh: MESH:C008216
 xref: PDBeChem:IVA;   PMID:12743728 "Europe PMC";   PPDB:3129
 cyclic_relationship: is_conjugate_acid_of CHEBI:48942


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isovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LEPR leptin receptor JBrowse link 1 65,420,652 65,637,493 RGD:6480464
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 JBrowse link 2 233,636,477 233,773,305 RGD:6480464
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 JBrowse link 2 233,729,127 233,773,299 RGD:6480464
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 JBrowse link 2 233,681,938 233,773,299 RGD:6480464
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 2 233,617,645 233,773,299 RGD:6480464
3-hydroxyisovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G FBXO32 F-box protein 32 JBrowse link 8 123,497,887 123,541,206 RGD:6480464
G USP16 ubiquitin specific peptidase 16 JBrowse link 21 29,024,617 29,054,488 RGD:6480464
G USP2 ubiquitin specific peptidase 2 JBrowse link 11 119,355,215 119,381,690 RGD:6480464
G USP28 ubiquitin specific peptidase 28 JBrowse link 11 113,797,875 113,875,572 RGD:6480464
fenvalerate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ACE angiotensin I converting enzyme JBrowse link 17 63,477,061 63,498,373 RGD:6480464
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 100,889,994 100,896,994 RGD:6480464
G ACOX1 acyl-CoA oxidase 1 JBrowse link 17 75,941,507 75,979,199 RGD:6480464
G ALPL alkaline phosphatase, biomineralization associated JBrowse link 1 21,508,984 21,578,412 RGD:6480464
G AR androgen receptor JBrowse link X 67,544,021 67,730,619 RGD:6480464
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:6480464
G C3 complement C3 JBrowse link 19 6,677,704 6,720,650 RGD:6480464
G CALM1 calmodulin 1 JBrowse link 14 90,396,502 90,408,275 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CD36 CD36 molecule JBrowse link 7 80,602,207 80,679,277 RGD:6480464
G CDK2 cyclin dependent kinase 2 JBrowse link 12 55,966,830 55,972,789 RGD:6480464
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:6480464
G CES1 carboxylesterase 1 JBrowse link 16 55,802,851 55,833,127 RGD:6480464
G CNST consortin, connexin sorting protein JBrowse link 1 246,566,337 246,668,595 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 JBrowse link 15 74,337,762 74,367,646 RGD:6480464
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 JBrowse link 10 102,830,531 102,837,413 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 JBrowse link 19 40,843,541 40,850,447 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 JBrowse link 10 94,762,681 94,855,547 RGD:6480464
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 JBrowse link 10 95,036,772 95,069,497 RGD:6480464
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6480464
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 JBrowse link 22 42,126,499 42,130,810 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 JBrowse link 1 47,137,425 47,149,738 RGD:6480464
G EPHX1 epoxide hydrolase 1 JBrowse link 1 225,810,074 225,845,563 RGD:6480464
G EPHX2 epoxide hydrolase 2 JBrowse link 8 27,491,143 27,597,559 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G ESR2 estrogen receptor 2 JBrowse link 14 64,226,707 64,338,631 RGD:6480464
G FOXO3 forkhead box O3 JBrowse link 6 108,559,825 108,684,774 RGD:6480464
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 154,531,390 154,547,569 RGD:6480464
G GGT1 gamma-glutamyltransferase 1 JBrowse link 22 24,583,750 24,629,005 RGD:6480464
G GOT1 glutamic-oxaloacetic transaminase 1 JBrowse link 10 99,396,870 99,430,624 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,502,217 144,507,174 RGD:6480464
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 4 157,220,584 157,370,583 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G GULP1 GULP PTB domain containing engulfment adaptor 1 JBrowse link 2 188,291,669 188,595,926 RGD:6480464
G GUSB glucuronidase beta JBrowse link 7 65,960,684 65,982,230 RGD:6480464
G HAP1 huntingtin associated protein 1 JBrowse link 17 41,717,739 41,734,646 RGD:6480464
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 JBrowse link 17 42,552,923 42,555,214 RGD:6480464
G ID2 inhibitor of DNA binding 2 JBrowse link 2 8,682,056 8,684,461 RGD:6480464
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:6480464
G IGF2 insulin like growth factor 2 JBrowse link 11 2,129,112 2,149,603 RGD:6480464
G ITGB5 integrin subunit beta 5 JBrowse link 3 124,761,948 124,901,411 RGD:6480464
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 JBrowse link 3 4,493,348 4,847,840 RGD:6480464
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 JBrowse link 6 33,621,322 33,696,562 RGD:6480464
G KYAT1 kynurenine aminotransferase 1 JBrowse link 9 128,832,942 128,882,558 RGD:6480464
G KYNU kynureninase JBrowse link 2 142,877,664 143,055,833 RGD:6480464
G MAOA monoamine oxidase A JBrowse link X 43,654,907 43,746,824 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 1 161,229,666 161,238,623 RGD:6480464
G NR3C2 nuclear receptor subfamily 3 group C member 2 JBrowse link 4 148,078,764 148,444,698 RGD:6480464
G PGR progesterone receptor JBrowse link 11 101,029,624 101,130,681 RGD:6480464
G PML promyelocytic leukemia JBrowse link 15 73,994,673 74,047,827 RGD:6480464
G PTGFRN prostaglandin F2 receptor inhibitor JBrowse link 1 116,909,916 116,990,358 RGD:6480464
G RXRA retinoid X receptor alpha JBrowse link 9 134,326,455 134,440,586 RGD:6480464
G RYR1 ryanodine receptor 1 JBrowse link 19 38,433,691 38,587,564 RGD:6480464
G SCN10A sodium voltage-gated channel alpha subunit 10 JBrowse link 3 38,697,110 38,794,010 RGD:6480464
G SCN1B sodium voltage-gated channel beta subunit 1 JBrowse link 19 35,030,470 35,040,449 RGD:6480464
G SCN2A sodium voltage-gated channel alpha subunit 2 JBrowse link 2 165,208,056 165,392,310 RGD:6480464
G SCN3A sodium voltage-gated channel alpha subunit 3 JBrowse link 2 165,087,526 165,204,295 RGD:6480464
G SCN3B sodium voltage-gated channel beta subunit 3 JBrowse link 11 123,629,187 123,654,607 RGD:6480464
G SLC38A1 solute carrier family 38 member 1 JBrowse link 12 46,183,063 46,269,149 RGD:6480464
G SLC38A2 solute carrier family 38 member 2 JBrowse link 12 46,358,188 46,372,774 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,622 31,668,931 RGD:6480464
G STAR steroidogenic acute regulatory protein JBrowse link 8 38,142,700 38,150,952 RGD:6480464
G TBX3 T-box transcription factor 3 JBrowse link 12 114,670,255 114,684,175 RGD:6480464
G TFF1 trefoil factor 1 JBrowse link 21 42,362,282 42,366,535 RGD:6480464
G THRA thyroid hormone receptor alpha JBrowse link 17 40,062,193 40,093,867 RGD:6480464
G THRB thyroid hormone receptor beta JBrowse link 3 24,117,153 24,495,708 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
G WNT10B Wnt family member 10B JBrowse link 12 48,965,340 48,979,587 RGD:6480464
flucythrinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AR androgen receptor JBrowse link X 67,544,021 67,730,619 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23680
    role 23568
      biological role 23529
        biochemical role 22887
          metabolite 22775
            eukaryotic metabolite 22452
              plant metabolite 19229
                isovaleric acid 89
                  (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                  2,3-dihydroxy-3-methylbutanoic acid + 0
                  2-(4-chlorophenyl)-3-methylbutyric acid + 79
                  2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                  2-hydroxy-3-methylbutyric acid + 0
                  3-hydroxyisovaleric acid + 5
                  N-isovaleryl-L-alanine 0
                  O-isovalerylcarnitine + 0
                  ananolignan J 0
                  ethyl isovalerate 0
                  isovaleryl-CoA 0
                  neurolenin A 0
                  neurolenin B 0
                  neurolenin C 0
                  neurolenin D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23680
    subatomic particle 23627
      composite particle 23627
        hadron 23627
          baryon 23627
            nucleon 23627
              atomic nucleus 23627
                atom 23627
                  main group element atom 23444
                    p-block element atom 23444
                      carbon group element atom 23145
                        carbon atom 23121
                          organic molecular entity 23121
                            organic group 21820
                              organic divalent group 21790
                                organodiyl group 21790
                                  carbonyl group 21761
                                    carbonyl compound 21761
                                      carboxylic acid 20787
                                        monocarboxylic acid 19761
                                          fatty acid 18122
                                            short-chain fatty acid 17733
                                              fatty acid 4:0 7105
                                                butyric acid 5388
                                                  methylbutyric acid 979
                                                    isovaleric acid 89
                                                      (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                                                      2,3-dihydroxy-3-methylbutanoic acid + 0
                                                      2-(4-chlorophenyl)-3-methylbutyric acid + 79
                                                      2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                                                      2-hydroxy-3-methylbutyric acid + 0
                                                      3-hydroxyisovaleric acid + 5
                                                      N-isovaleryl-L-alanine 0
                                                      O-isovalerylcarnitine + 0
                                                      ananolignan J 0
                                                      ethyl isovalerate 0
                                                      isovaleryl-CoA 0
                                                      neurolenin A 0
                                                      neurolenin B 0
                                                      neurolenin C 0
                                                      neurolenin D 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.