Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:isovaleric acid
go back to main search page
Accession:CHEBI:28484 term browser browse the term
Definition:A C5, branched-chain saturated fatty acid.
Synonyms:related_synonym: 3-Methylbutanoic acid;   3-Methylbuttersaeure;   3-methyl-n-butyric acid;   3-methylbutyric acid;   Formula=C5H10O2;   InChI=1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7);   InChIKey=GWYFCOCPABKNJV-UHFFFAOYSA-N;   Isovalerate;   Isovaleriansaeure;   SMILES=CC(C)CC(O)=O;   beta-methylbutyric acid;   delphinic acid;   isobutylformic acid;   isopentanoic acid;   isopropylacetic acid;   isovalerianic acid
 alt_id: CHEBI:24930;   CHEBI:43426;   CHEBI:6069
 xref: Beilstein:1098522 "ChemIDplus";   CAS:503-74-2 "ChemIDplus";   CAS:503-74-2 "KEGG COMPOUND";   CAS:503-74-2 "NIST Chemistry WebBook";   DrugBank:DB03750;   Gmelin:101117 "Gmelin";   KEGG:C08262;   KNApSAcK:C00001189;   LIPID_MAPS_instance:LMFA01020181 "LIPID MAPS"
 xref_mesh: MESH:C008216
 xref: PDBeChem:IVA;   PMID:12743728 "Europe PMC";   PPDB:3129
 cyclic_relationship: is_conjugate_acid_of CHEBI:48942


show annotations for term's descendants       view all columns           Sort by:
 
isovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
3-hydroxyisovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Fbxo32 F-box protein 32 JBrowse link 7 98,065,664 98,098,071 RGD:6480464
G Usp16 ubiquitin specific peptidase 16 JBrowse link 11 27,101,213 27,130,345 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 8 48,403,985 48,432,525 RGD:6480464
G Usp28 ubiquitin specific peptidase 28 JBrowse link 8 53,295,188 53,355,572 RGD:6480464
fenvalerate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:6480464
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:6480464
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:6480464
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Cnst consortin, connexin sorting protein JBrowse link 13 97,838,325 97,915,131 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 JBrowse link 5 134,492,734 134,507,158 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:6480464
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gulp1 GULP PTB domain containing engulfment adaptor 1 JBrowse link 9 51,263,484 51,538,066 RGD:6480464
G Gusb glucuronidase, beta JBrowse link 12 30,202,066 30,215,583 RGD:6480464
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:6480464
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:6480464
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Itgb5 integrin subunit beta 5 JBrowse link 11 70,056,500 70,172,164 RGD:6480464
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:6480464
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 JBrowse link 20 5,645,894 5,711,702 RGD:6480464
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:6480464
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 JBrowse link 19 34,408,275 34,761,003 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:6480464
G Ptgfrn prostaglandin F2 receptor inhibitor JBrowse link 2 203,423,143 203,494,391 RGD:6480464
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:6480464
G Ryr1 ryanodine receptor 1 JBrowse link 1 87,959,596 88,066,252 RGD:6480464
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:6480464
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:6480464
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:6480464
G Scn3a sodium voltage-gated channel alpha subunit 3 JBrowse link 3 51,530,897 51,643,140 RGD:6480464
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:6480464
G Slc38a1 solute carrier family 38, member 1 JBrowse link 7 137,970,555 138,040,098 RGD:6480464
G Slc38a2 solute carrier family 38, member 2 JBrowse link 7 138,088,654 138,100,869 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:6480464
flucythrinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        biochemical role 19130
          metabolite 19098
            eukaryotic metabolite 18740
              plant metabolite 17040
                isovaleric acid 87
                  (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                  2,3-dihydroxy-3-methylbutanoic acid + 0
                  2-(4-chlorophenyl)-3-methylbutyric acid + 79
                  2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                  2-hydroxy-3-methylbutyric acid + 0
                  3-hydroxyisovaleric acid + 5
                  N-isovaleryl-L-alanine 0
                  O-isovalerylcarnitine + 0
                  ananolignan J 0
                  ethyl isovalerate 0
                  isovaleryl-CoA 0
                  neurolenin A 0
                  neurolenin B 0
                  neurolenin C 0
                  neurolenin D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        monocarboxylic acid 17254
                                          fatty acid 15818
                                            short-chain fatty acid 15514
                                              fatty acid 4:0 7002
                                                butyric acid 5271
                                                  methylbutyric acid 972
                                                    isovaleric acid 87
                                                      (E)-2-(methoxyimino)-3-methylbutanoic acid 0
                                                      2,3-dihydroxy-3-methylbutanoic acid + 0
                                                      2-(4-chlorophenyl)-3-methylbutyric acid + 79
                                                      2-(4-hydroxyphenyl)-3-methylbutyric acid + 4
                                                      2-hydroxy-3-methylbutyric acid + 0
                                                      3-hydroxyisovaleric acid + 5
                                                      N-isovaleryl-L-alanine 0
                                                      O-isovalerylcarnitine + 0
                                                      ananolignan J 0
                                                      ethyl isovalerate 0
                                                      isovaleryl-CoA 0
                                                      neurolenin A 0
                                                      neurolenin B 0
                                                      neurolenin C 0
                                                      neurolenin D 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.