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G |
Alb |
albumin |
multiple interactions |
ISO |
allicin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein] |
CTD |
PMID:32040233 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in increased expression of BAX protein] |
CTD |
PMID:27561292 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
allicin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein] |
CTD |
PMID:32040233 |
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NCBI chr13:22,689,783...22,853,920
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in decreased expression of BCL2L1 protein] |
CTD |
PMID:27561292 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
allicin inhibits the reaction [Acetaminophen results in increased expression of CASP1 protein] |
CTD |
PMID:32040233 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
allicin inhibits the reaction [Acetaminophen results in increased expression of GPT protein] |
CTD |
PMID:32040233 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in decreased expression of HMOX1 protein] |
CTD |
PMID:27561292 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
allicin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:12723939 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
allicin inhibits the reaction [IL1B protein affects the localization of RELA protein]; IL1B protein promotes the reaction [allicin results in increased phosphorylation of MAPK1 protein]; IL1B protein promotes the reaction [allicin results in increased phosphorylation of MAPK3 protein] allicin inhibits the reaction [Acetaminophen results in increased expression of IL1B protein] allicin results in increased expression of IL1B mRNA [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] |
CTD |
PMID:25729217 PMID:32040233 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
multiple interactions |
EXP |
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein] |
CTD |
PMID:25729217 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Klf9 |
Kruppel-like factor 9 |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in decreased expression of KLF9 protein] |
CTD |
PMID:27561292 |
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NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
allicin results in increased phosphorylation of MAPK1 protein IL1B protein promotes the reaction [allicin results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:25729217 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
IL1B protein promotes the reaction [allicin results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:25729217 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in decreased expression of NFE2L2 protein] |
CTD |
PMID:27561292 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
allicin inhibits the reaction [Acetaminophen results in increased expression of NLRP3 protein] |
CTD |
PMID:32040233 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in decreased expression of NQO1 protein] |
CTD |
PMID:27561292 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
allicin inhibits the reaction [arsenic trioxide results in increased expression of RELA protein]; allicin inhibits the reaction [IL1B protein affects the localization of RELA protein] |
CTD |
PMID:25729217 PMID:27561292 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
allicin inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; allicin inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; allicin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] |
CTD |
PMID:12723939 PMID:25729217 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity multiple interactions |
EXP ISO |
allicin results in increased activity of TRPA1 protein allicin binds to and results in increased activity of TRPA1 protein [allicin binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; allicin binds to and results in increased activity of TRPA1 protein |
CTD |
PMID:17684094 PMID:17825279 PMID:20086034 |
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NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
affects response to substance increases response to substance |
ISO |
TRPV1 protein affects the susceptibility to allicin TRPV1 protein mutant form results in increased susceptibility to allicin |
CTD |
PMID:17110039 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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