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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluorene
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Accession:CHEBI:28266 term browser browse the term
Definition:An ortho-fused tricyclic hydrocarbon that is a major component of fossil fuels and their derivatives
Synonyms:related_synonym: 2,2'-Methylenebiphenyl;   2,3-benzindene;   9H-fluorene;   Diphenylenemethane;   Fluoren;   Formula=C13H10;   InChI=1S/C13H10/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)12/h1-8H,9H2;   InChIKey=NIHNNTQXNPWCJQ-UHFFFAOYSA-N;   SMILES=C1C2=CC=CC=C2C2=CC=CC=C12;   o-biphenylenemethane;   o-biphenylmethane
 alt_id: CHEBI:24058;   CHEBI:5112
 xref: Beilstein:1363491;   CAS:86-73-7;   Chemspider:6592;   FooDB:FDB007671;   Gmelin:28451;   KEGG:C07715
 xref_mesh: MESH:C041509
 xref: MetaCyc:FLUORENE;   PDBeChem:9FL;   PMID:15120562;   PMID:15800860;   PMID:16539455;   PMID:17129129;   PMID:17243671;   PMID:17285163;   PMID:17824593;   PMID:19060398;   PMID:21110374;   PMID:21478643;   PMID:23202077;   PMID:24584240;   PMID:24889657;   PMID:28409789;   Reaxys:1363491;   UM-BBD_compID:c0388;   Wikipedia:Fluorene



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fluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [acenaphthene co-treated with anthracene co-treated with 1,12-benzoperylene co-treated with 1,2,5,6-dibenzanthracene co-treated with fluorene co-treated with naphthalene co-treated with phenanthrene] results in increased activity of AHR protein
fluorene results in increased activity of AHR protein
CTD PMID:17665671 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor decreases methylation ISO fluorene metabolite results in decreased methylation of AHRR gene CTD PMID:32385190 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Cat catalase increases activity
multiple interactions
ISO fluorene results in increased activity of CAT protein
[phenanthrene co-treated with fluorene] results in increased activity of CAT protein
CTD PMID:32856796 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP fluorene results in increased expression of CYP1A1 protein CTD PMID:10445401 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
ISO fluorene results in increased activity of CYP1A2 protein
[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA
CTD PMID:7750161 PMID:8001243 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP fluorene results in increased expression of CYP2B1 protein CTD PMID:10445401 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP fluorene results in increased expression of CYP3A2 protein CTD PMID:10445401 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 decreases methylation ISO fluorene metabolite results in decreased methylation of F2RL3 gene CTD PMID:32385190 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
decreases localization
ISO fluorene results in decreased expression of GJA1 protein
fluorene results in decreased localization of GJA1 protein
CTD PMID:30668803 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO fluorene results in increased expression of IL6 mRNA; fluorene results in increased expression of IL6 protein
[fluorene co-treated with phenanthrene] results in increased expression of IL6 mRNA; [fluorene co-treated with phenanthrene] results in increased expression of IL6 protein
CTD PMID:32856796 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [fluorene results in increased expression of NOS3 mRNA]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [fluorene results in increased expression of NOS3 protein]; nickel chloride inhibits the reaction [fluorene results in increased expression of NOS3 protein]; Proadifen inhibits the reaction [fluorene results in increased expression of NOS3 protein]
fluorene results in increased expression of NOS3 mRNA; fluorene results in increased expression of NOS3 protein
CTD PMID:15183461 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO fluorene results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO fluorene results in decreased expression of TGFB1 mRNA CTD PMID:32856796 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO [fluorene co-treated with phenanthrene] results in increased expression of TNF mRNA; [fluorene co-treated with phenanthrene] results in increased expression of TNF protein
fluorene results in increased expression of TNF mRNA; fluorene results in increased expression of TNF protein
CTD PMID:32856796 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
1-Methylfluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects binding EXP 1-methylfluorene binds to AHR protein CTD PMID:3024361 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
2-acetamidofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin increases expression ISO 2-Acetylaminofluorene results in increased expression of AAAS mRNA CTD PMID:21607683 NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression
multiple interactions
increases activity
ISO
EXP
2-Acetylaminofluorene results in decreased expression of ABCB1 mRNA
2-Acetylaminofluorene results in increased expression of ABCB1 mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1A mRNA
lipopolysaccharide, E coli O55-B5 inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1A mRNA]
2-Acetylaminofluorene results in increased expression of ABCB1 mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1 protein
Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]
2-Acetylaminofluorene results in increased activity of ABCB1 protein
[2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA; [2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA; [RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
CTD PMID:11170838 PMID:11960367 PMID:12387747 PMID:17303067 PMID:17669244 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of ABCB1B mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1B protein
[2-Acetylaminofluorene results in increased abundance of Reactive Oxygen Species] which results in increased expression of ABCB1B mRNA; lipopolysaccharide, E coli O55-B5 inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]; RELA protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]
CTD PMID:11020383 PMID:11170838 PMID:12801967 PMID:17070881 PMID:22084566 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ABCC1 mRNA CTD PMID:12801967 PMID:17669244 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO 2-Acetylaminofluorene results in increased expression of ABCC10 mRNA CTD PMID:12566991 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of ABCC2 mRNA
2-Acetylaminofluorene results in increased expression of ABCC2 mRNA; 2-Acetylaminofluorene results in increased expression of ABCC2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]
CTD PMID:10691972 PMID:16381673 PMID:16426233 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of ABCC3 mRNA; 2-Acetylaminofluorene results in increased expression of ABCC3 protein CTD PMID:10691972 PMID:12801967 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
increases activity
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of ABCG2 mRNA
2-Acetylaminofluorene results in increased activity of ABCG2 protein
2-Acetylaminofluorene results in increased expression of ABCG2 mRNA; 2-Acetylaminofluorene results in increased expression of ABCG2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]
CTD PMID:12819005 PMID:16381673 PMID:17538966 PMID:17669244 PMID:27475308 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ACAA2 mRNA CTD PMID:14656948 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression EXP 2-Acetylaminofluorene results in increased expression of ACOT9 mRNA CTD PMID:21784091 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of AEN mRNA CTD PMID:17070881 PMID:21607683 PMID:22584684 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afp alpha-fetoprotein multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of AFP protein; [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of AFP protein
2-Acetylaminofluorene results in increased expression of AFP mRNA; 2-Acetylaminofluorene results in increased expression of AFP protein
CTD PMID:6187438 PMID:11350689 PMID:11813887 PMID:15133858 PMID:17538966 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO 2-Acetylaminofluorene results in increased expression of AHR mRNA CTD PMID:25224404 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of AK1 mRNA CTD PMID:17317680 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO 2-Acetylaminofluorene results in increased expression of AKR1B3 mRNA CTD PMID:17317680 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AKR1B10 mRNA
2-Acetylaminofluorene results in increased expression of AKR1B10 mRNA
CTD PMID:14656948 PMID:26198647 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-Acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein; [2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA
2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:11960367 PMID:17303067 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of ALB protein
2-Acetylaminofluorene results in increased expression of ALB protein
CTD PMID:6187438 PMID:15133858 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 PMID:22584684 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A3 mRNA CTD PMID:22584684 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ALDH3A1 mRNA] CTD PMID:17317680 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Tocotrienols affects the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein] CTD PMID:15548946 PMID:15554553 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ANAPC11 mRNA CTD PMID:22584684 NCBI chr10:105,875,209...105,886,307 JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of ANXA3 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ANXA3 mRNA]
[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of ANXA3 mRNA
CTD PMID:17317680 PMID:18071240 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa8 annexin A8 increases expression ISO 2-Acetylaminofluorene results in increased expression of ANXA8 mRNA CTD PMID:17317680 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of AOX1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AOX1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apod apolipoprotein D decreases expression ISO 2-Acetylaminofluorene results in decreased expression of APOD mRNA CTD PMID:20713471 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Aqp5 aquaporin 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of AQP5 mRNA CTD PMID:17187413 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of AREG mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of AREG mRNA]
CTD PMID:17317680 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ASGR1 mRNA CTD PMID:17187413 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-Acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of BAX mRNA]
2-Acetylaminofluorene results in increased expression of BAX mRNA
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]
CTD PMID:11915028 PMID:17070881 PMID:17317680 PMID:19167416 PMID:21607683 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein]
2-Acetylaminofluorene results in increased expression of BCL2 mRNA
CTD PMID:11915028 PMID:19167416 PMID:22213190 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein]
2-Acetylaminofluorene results in increased expression of BCL2L1 mRNA
CTD PMID:11915028 PMID:21607683 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of BIRC5 mRNA CTD PMID:19167416 PMID:22213190 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression EXP 2-Acetylaminofluorene results in increased expression of BRCA1 mRNA CTD PMID:19167416 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of BTG2 mRNA CTD PMID:17070881 PMID:21607683 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of BZW1 mRNA CTD PMID:17317680 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP 2-Acetylaminofluorene results in decreased expression of C4BPA mRNA CTD PMID:16510358 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C6 complement C6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of C6 mRNA CTD PMID:22584684 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G C7 complement C7 increases expression EXP 2-Acetylaminofluorene results in increased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CACNA2D1 mRNA CTD PMID:17187413 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CADM1 protein CTD PMID:17326163 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAR2 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP 2-Acetylaminofluorene inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of CASP3 protein]; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein] CTD PMID:12907702 PMID:23665045 PMID:26364502 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein] CTD PMID:23665045 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 increases activity
increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased activity of CASP9 protein
2-Acetylaminofluorene results in increased expression of CASP9 protein
Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]
CTD PMID:23665045 PMID:26364502 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of CAT protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of CAT protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein] CTD PMID:17761372 PMID:23665045 PMID:26364502 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cavin3 caveolae associated protein 3 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAVIN3 mRNA CTD PMID:14656948 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 2-Acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CBR1 mRNA CTD PMID:21607683 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cck cholecystokinin decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CCK mRNA CTD PMID:22584684 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression EXP 2-Acetylaminofluorene affects the expression of CCL2 mRNA; 2-Acetylaminofluorene affects the expression of CCL2 protein CTD PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of CCL7 protein CTD PMID:25051504 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CCN2 mRNA; 2-Acetylaminofluorene results in increased expression of CCN2 protein
Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA]
CTD PMID:15940639 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CCNA2 protein CTD PMID:15158336 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of CCNB1 protein
2-Acetylaminofluorene results in increased expression of CCNB1 mRNA
CTD PMID:15158336 PMID:22584684 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of CCNB2 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CCNB2 mRNA]
CTD PMID:17317680 PMID:19167416 PMID:22584684 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA]
2-Acetylaminofluorene results in increased expression of CCND1 mRNA
CTD PMID:14633663 PMID:22584684 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 multiple interactions
decreases activity
EXP 2-Acetylaminofluorene inhibits the reaction [CDK2 protein binds to CCNE1 protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA]
2-Acetylaminofluorene results in decreased activity of CCNE1 protein
CTD PMID:10708481 PMID:14633663 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccng1 cyclin G1 decreases expression
increases expression
EXP
ISO
2-Acetylaminofluorene results in decreased expression of CCNG1 mRNA
2-Acetylaminofluorene results in increased expression of CCNG1 mRNA
CTD PMID:17070881 PMID:17317680 PMID:19167416 PMID:21607683 PMID:22584684 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 2-Acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881 PMID:21784091 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP
IEP
2-Acetylaminofluorene results in increased expression of CD44 mRNA
2-Fluorenylacetamide increases CD44 mRNA in liver, and protein in liver and serum
CTD
RGD
PMID:17187413 PMID:22584684 PMID:31966914 RGD:25823185 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 protein CTD PMID:16317707 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDCA3 mRNA CTD PMID:22584684 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdh13 cadherin 13 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH13 mRNA CTD PMID:21784091 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdh22 cadherin 22 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH22 mRNA CTD PMID:17187413 NCBI chr 3:153,845,563...153,970,630
Ensembl chr 3:153,845,787...153,970,588
JBrowse link
G Cdh3 cadherin 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH3 mRNA CTD PMID:17187413 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDK1 mRNA CTD PMID:19167416 PMID:22584684 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
EXP 2-Acetylaminofluorene inhibits the reaction [CDK2 protein binds to CCNE1 protein]; 2-Acetylaminofluorene results in decreased localization of and results in decreased phosphorylation of and results in decreased activity of CDK2 protein
2-Acetylaminofluorene results in decreased activity of CDK2 protein
CTD PMID:10708481 PMID:15158336 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases activity EXP 2-Acetylaminofluorene results in increased activity of CDK4 protein CTD PMID:15158336 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
EXP
ISO
2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of CDKN1A protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA]; pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]
2-Acetylaminofluorene results in increased expression of CDKN1A mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CDKN1A mRNA]
2-Acetylaminofluorene results in increased expression of CDKN1A mRNA; 2-Acetylaminofluorene results in increased expression of CDKN1A protein
CTD PMID:10708481 PMID:11003613 PMID:14633663 PMID:17070881 PMID:17317680 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP 2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]; Pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]] CTD PMID:17582756 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression
increases methylation
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A protein
2-Acetylaminofluorene results in increased expression of CDKN2A mRNA
2-Acetylaminofluorene results in increased methylation of CDKN2A gene; 2-Acetylaminofluorene results in increased methylation of CDKN2A promoter
CTD PMID:16317707 PMID:18204080 PMID:19167416 PMID:20188851 PMID:22213190 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of CDKN2B mRNA CTD PMID:17317680 PMID:22213190 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP 2-Acetylaminofluorene results in increased expression of CDKN2C mRNA CTD PMID:22584684 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDKN3 mRNA CTD PMID:22213190 PMID:22584684 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CEBPA protein CTD PMID:20188851 PMID:21785164 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression
EXP 2-Acetylaminofluorene inhibits the reaction [CEBPB protein binds to HAMP promoter]
2-Acetylaminofluorene results in decreased expression of CEBPB protein
CTD PMID:21785164 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Ces3a carboxylesterase 3a increases expression ISO 2-Acetylaminofluorene results in increased expression of CES3 mRNA CTD PMID:20713471 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CKMT1 mRNA CTD PMID:17317680 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
JBrowse link
G Cldn4 claudin 4 increases expression EXP 2-Acetylaminofluorene results in increased expression of CLDN4 mRNA CTD PMID:17187413 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cldn7 claudin 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of CLDN7 mRNA CTD PMID:17187413 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clu clusterin multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CLU mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CLU mRNA CTD PMID:14656948 PMID:16158176 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase increases expression EXP 2-Acetylaminofluorene results in increased expression of CMAS protein CTD PMID:6331524 NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of COL17A1 mRNA] CTD PMID:17317680 NCBI chr 1:246,530,589...246,577,632
Ensembl chr 1:246,531,367...246,577,632
JBrowse link
G Commd3 COMM domain containing 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of COMMD3 mRNA CTD PMID:17317680 NCBI chr17:81,327,451...81,331,183
Ensembl chr17:81,327,405...81,331,177
JBrowse link
G Coq6 coenzyme Q6 monooxygenase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of COQ6 mRNA CTD PMID:16158176 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of CPS1 protein CTD PMID:11813887 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Crebbp CREB binding protein decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CREBBP mRNA CTD PMID:22213190 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-Acetylaminofluorene results in increased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CRYL1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CRYL1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csta cystatin A affects expression ISO 2-Acetylaminofluorene affects the expression of CSTA mRNA CTD PMID:27825931 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CX3CL1 mRNA CTD PMID:17187413 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL1 protein CTD PMID:25051504 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL10 protein CTD PMID:25051504 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 protein
2-Acetylaminofluorene results in increased expression of CXCL12 mRNA; 2-Acetylaminofluorene results in increased expression of CXCL12 protein
CTD PMID:12626097 PMID:15579440 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL2 protein CTD PMID:25051504 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CXCR4 mRNA
[2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCR4 protein
CTD PMID:12626097 PMID:15579440 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydrolysis
multiple interactions
increases expression
ISO
EXP
CYP1A1 results in increased hydrolysis of 2-Acetylaminofluorene
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP1A1 mRNA]
2-Acetylaminofluorene analog results in increased expression of CYP1A1 protein; 2-Acetylaminofluorene results in increased expression of CYP1A1 mRNA; 2-Acetylaminofluorene results in increased expression of CYP1A1 protein
CTD PMID:2334931 PMID:10445401 PMID:11888708 PMID:15916741 PMID:20713471 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
decreases expression
multiple interactions
increases hydrolysis
increases activity
ISO
EXP
CYP1A2 protein affects the metabolism of 2-Acetylaminofluorene
2-Acetylaminofluorene results in increased expression of CYP1A2 protein
2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA
2-Acetylaminofluorene analog results in decreased expression of CYP1A2 protein; 2-Acetylaminofluorene results in decreased expression of CYP1A2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]
CYP1A2 results in increased hydrolysis of 2-Acetylaminofluorene
CYP1A2 protein results in increased activity of 2-Acetylaminofluorene
CTD PMID:2334931 PMID:2655891 PMID:15450435 PMID:15916741 PMID:16381673 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA]
CTD PMID:17317680 PMID:20713471 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CYP2A22 mRNA CTD PMID:21607683 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression
increases expression
EXP 2-Acetylaminofluorene analog results in decreased expression of CYP2B1 protein; 2-Acetylaminofluorene results in decreased expression of CYP2B1 protein
2-Acetylaminofluorene results in increased expression of CYP2B1 protein
CTD PMID:10445401 PMID:15916741 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP 2-Acetylaminofluorene analog results in decreased expression of CYP2B2 protein; 2-Acetylaminofluorene results in decreased expression of CYP2B2 protein CTD PMID:15916741 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein]
2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein; 2-Acetylaminofluorene results in increased expression of CYP2E1 protein
CTD PMID:14656948 PMID:15916741 PMID:16158176 PMID:17393424 PMID:23665045 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP3A2 protein CTD PMID:10445401 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA; 2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 protein
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP3A23-3A1 mRNA; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]; Trabectedin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]
CTD PMID:12504080 PMID:14656948 PMID:16158176 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dap death-associated protein multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of DAP mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of DAP mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO 2-Acetylaminofluorene results in increased expression of DDIT4L mRNA CTD PMID:21607683 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DDR1 mRNA CTD PMID:17187413 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Des desmin increases expression EXP 2-Acetylaminofluorene results in increased expression of DES mRNA CTD PMID:17187413 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) decreases activity EXP 2-Acetylaminofluorene results in decreased activity of DHODH protein CTD PMID:6331524 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DLK1 mRNA; 2-Acetylaminofluorene results in increased expression of DLK1 protein CTD PMID:15567716 PMID:17187413 PMID:17538966 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of DMP1 mRNA CTD PMID:17317680 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of E2F1 protein
2-Acetylaminofluorene results in increased expression of E2F1 mRNA
CTD PMID:15158336 PMID:19167416 PMID:22213190 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f3 E2F transcription factor 3 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of E2F3 protein CTD PMID:15158336 PMID:19167416 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G E2f4 E2F transcription factor 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of E2F4 protein CTD PMID:15158336 NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO 2-Acetylaminofluorene results in increased expression of EDA2R mRNA CTD PMID:21607683 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Egf epidermal growth factor decreases localization
multiple interactions
EXP 2-Acetylaminofluorene results in decreased localization of EGF protein
2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein]
CTD PMID:10900465 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
EXP 2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein]
2-Acetylaminofluorene results in decreased expression of EGFR mRNA
CTD PMID:10900465 PMID:22213190 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of EGR1 mRNA CTD PMID:19167416 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of EI24 mRNA] CTD PMID:17317680 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G Emp2 epithelial membrane protein 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of EMP2 mRNA CTD PMID:21607683 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of ENC1 mRNA CTD PMID:21607683 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eno1 enolase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of ENO1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ENO1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 2-Acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881 PMID:17187413 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Epha1 Eph receptor A1 increases expression ISO 2-Acetylaminofluorene results in increased expression of EPHA1 mRNA CTD PMID:17317680 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 PMID:17317680 PMID:21607683 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of ERBB2 protein CTD PMID:11350689 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ESR1 mRNA CTD PMID:19167416 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of EXOC4 mRNA CTD PMID:21607683 NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723
JBrowse link
G Fam110a family with sequence similarity 110, member A increases expression ISO 2-Acetylaminofluorene results in increased expression of FAM110A mRNA CTD PMID:21607683 NCBI chr 3:140,474,484...140,485,074
Ensembl chr 3:140,474,249...140,485,093
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of FAS mRNA CTD PMID:17070881 PMID:22584684 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxw9 F-box and WD repeat domain containing 9 increases expression ISO 2-Acetylaminofluorene results in increased expression of FBXW9 mRNA CTD PMID:21607683 NCBI chr19:23,090,534...23,097,439
Ensembl chr19:23,090,534...23,097,439
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 affects expression EXP 2-Acetylaminofluorene affects the expression of FLT3 mRNA CTD PMID:18031378 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Fn1 fibronectin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of FN1 mRNA CTD PMID:15940639 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of FOS protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of FOS protein] CTD PMID:17696247 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of FTH1 protein CTD PMID:21785164 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC1 protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC1 protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC1 protein] CTD PMID:15554553 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gaa alpha glucosidase increases expression ISO 2-Acetylaminofluorene results in increased expression of GAA mRNA CTD PMID:17317680 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of GAS2L3 mRNA CTD PMID:20713471 NCBI chr 7:23,803,578...23,836,816 JBrowse link
G Gcgr glucagon receptor multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCGR mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GCGR mRNA CTD PMID:14656948 PMID:16158176 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of GCLC mRNA
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLC mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GCLC mRNA
CTD PMID:14656948 PMID:16158176 PMID:16426233 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO 2-Acetylaminofluorene results in increased expression of GDF15 mRNA CTD PMID:21607683 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of GGT1 mRNA
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein]
CTD PMID:15554553 PMID:17187413 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of GJA1 mRNA; 2-Acetylaminofluorene results in increased expression of GJA1 protein CTD PMID:15133858 PMID:17187413 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of GJB2 mRNA CTD PMID:22213190 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of GLRX3 mRNA CTD PMID:17317680 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Gpc3 glypican 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of GPC3 mRNA CTD PMID:17187413 NCBI chr  X:131,868,983...132,236,837
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GPX2 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of GRIA3 mRNA CTD PMID:17070881 PMID:21607683 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of GRINA mRNA CTD PMID:21607683 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
decreases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSR mRNA; Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of GSR protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein] CTD PMID:16158176 PMID:23665045 PMID:26364502 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression ISO 2-Acetylaminofluorene results in increased expression of GSS mRNA CTD PMID:17317680 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of GSTA2 mRNA
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTA2 mRNA
CTD PMID:14656948 PMID:16158176 PMID:17317680 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression ISO 2-Acetylaminofluorene results in increased expression of GSTA1 mRNA CTD PMID:17317680 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO 2-Acetylaminofluorene results in increased expression of GSTA2 mRNA CTD PMID:17317680 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSTP1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein]; herbal compound 861 inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA]; herbal compound 861 inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein]
2-Acetylaminofluorene results in increased expression of GSTP1 mRNA; 2-Acetylaminofluorene results in increased expression of GSTP1 protein
CTD PMID:12497209 PMID:12781041 PMID:12907702 PMID:15554553 PMID:17393424 More... NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of GTSE1 mRNA CTD PMID:21607683 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G H2ax H2A.X variant histone increases expression EXP 2-Acetylaminofluorene results in increased expression of H2AX protein CTD PMID:26338220 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of HADHA mRNA CTD PMID:16158176 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
EXP 2-Acetylaminofluorene inhibits the reaction [CEBPB protein binds to HAMP promoter]
2-Acetylaminofluorene results in decreased expression of HAMP mRNA
CTD PMID:21785164 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hebp2 heme binding protein 2 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of HEBP2 mRNA] CTD PMID:17317680 NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA; beta-ionone promotes the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA] CTD PMID:20435455 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of HMOX1 mRNA CTD PMID:22584684 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP 2-Acetylaminofluorene results in increased expression of HRAS protein CTD PMID:11350689 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Ica1 islet cell autoantigen 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ICA1 mRNA CTD PMID:21784091 NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO 2-Acetylaminofluorene results in increased expression of ID1 mRNA CTD PMID:15120964 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ifna1 interferon, alpha 1 multiple interactions EXP IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA]; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA]; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA] CTD PMID:14633663 NCBI chr 5:103,095,767...103,098,260 JBrowse link
G Ifna2 interferon alpha 2 multiple interactions EXP IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] CTD PMID:11915028 PMID:15368444 NCBI chr 5:103,258,617...103,259,195 JBrowse link
G Ifng interferon gamma multiple interactions EXP 2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein] CTD PMID:14736494 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of IGF2 mRNA CTD PMID:22213190 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO 2-Acetylaminofluorene results in decreased expression of IGFALS mRNA CTD PMID:21607683 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases activity ISO 2-Acetylaminofluorene results in increased activity of IKBKB protein CTD PMID:11960367 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 affects expression EXP 2-Acetylaminofluorene affects the expression of IL10 protein CTD PMID:25051504 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B increases expression EXP 2-Acetylaminofluorene results in increased expression of IL12B protein CTD PMID:25051504 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression
increases expression
ISO
EXP
2-Acetylaminofluorene inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
2-Acetylaminofluorene affects the expression of IL1B mRNA
2-Acetylaminofluorene results in increased expression of IL1B protein
CTD PMID:14670622 PMID:25051504 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 2-Acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il33 interleukin 33 increases expression ISO 2-Acetylaminofluorene results in increased expression of IL33 mRNA CTD PMID:17317680 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il5 interleukin 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of IL5 protein CTD PMID:25051504 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of IL6 protein CTD PMID:25051504 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb4 integrin subunit beta 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of ITGB4 mRNA CTD PMID:17317680 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein] CTD PMID:17696247 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdm6a lysine demethylase 6A decreases expression EXP 2-Acetylaminofluorene results in decreased expression of KDM6A mRNA CTD PMID:22213190 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kif11 kinesin family member 11 increases expression EXP 2-Acetylaminofluorene results in increased expression of KIF11 mRNA CTD PMID:22584684 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of KIT protein CTD PMID:15133858 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Krt15 keratin 15 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of KRT15 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT15 mRNA]
CTD PMID:17317680 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Krt19 keratin 19 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of KRT19 mRNA; 2-Acetylaminofluorene results in increased expression of KRT19 protein
[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of KRT19 protein
CTD PMID:15133858 PMID:17187413 PMID:17661067 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Krt20 keratin 20 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of KRT20 mRNA CTD PMID:17317680 NCBI chr10:84,384,802...84,394,107
Ensembl chr10:84,384,802...84,394,107
JBrowse link
G Krt23 keratin 23 multiple interactions
increases expression
ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT23 mRNA] CTD PMID:17317680 NCBI chr10:84,434,675...84,450,722
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Krt4 keratin 4 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of KRT4 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT4 mRNA]
CTD PMID:17317680 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
JBrowse link
G Krt8 keratin 8 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of KRT8 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lep leptin increases expression EXP 2-Acetylaminofluorene results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lig4 DNA ligase 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of LIG4 mRNA CTD PMID:19167416 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO 2-Acetylaminofluorene results in increased expression of LY6D mRNA CTD PMID:17317680 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression ISO 2-Acetylaminofluorene results in increased expression of LY6E mRNA CTD PMID:21607683 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of LYPD3 mRNA] CTD PMID:17317680 NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
JBrowse link
G Lzic leucine zipper and CTNNBIP1 domain containing increases expression ISO 2-Acetylaminofluorene results in increased expression of LZIC mRNA CTD PMID:21607683 NCBI chr 5:159,928,260...159,941,512
Ensembl chr 5:159,920,439...159,939,685
JBrowse link
G Mal mal, T-cell differentiation protein increases expression ISO 2-Acetylaminofluorene results in increased expression of MAL mRNA CTD PMID:17317680 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP 2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17546627 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mat1a methionine adenosyltransferase 1A affects acetylation
decreases expression
affects methylation
EXP 2-Acetylaminofluorene affects the acetylation of MAT1A exon; 2-Acetylaminofluorene affects the acetylation of MAT1A promoter
2-Acetylaminofluorene results in decreased expression of MAT1A mRNA
2-Acetylaminofluorene affects the methylation of MAT1A exon; 2-Acetylaminofluorene affects the methylation of MAT1A promoter
CTD PMID:22213190 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Matn2 matrilin 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MATN2 mRNA; 2-Acetylaminofluorene results in increased expression of MATN2 protein CTD PMID:17513098 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113
JBrowse link
G Mbl2 mannose binding lectin 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of MBL2 mRNA CTD PMID:21607683 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein
2-Acetylaminofluorene results in increased expression of MDM2 mRNA; 2-Acetylaminofluorene results in increased expression of MDM2 protein
CTD PMID:11003613 PMID:19167416 PMID:21607683 PMID:22213190 PMID:22584684 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
decreases expression
EXP 2-Acetylaminofluorene results in increased expression of MGMT mRNA
2-Acetylaminofluorene results in decreased expression of MGMT mRNA
CTD PMID:17070881 PMID:22213190 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MGST2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MGST2 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mir106b microRNA 106b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR106B mRNA CTD PMID:19167416 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Mir125b1 microRNA 125b-1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR125B-1 mRNA CTD PMID:19167416 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir130b microRNA 130b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR130B mRNA CTD PMID:19167416 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
JBrowse link
G Mir132 microRNA 132 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR132 mRNA CTD PMID:19167416 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
JBrowse link
G Mir146b microRNA 146b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR146B mRNA CTD PMID:19167416 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir155 microRNA 155 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR155 mRNA CTD PMID:19167416 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir17 microRNA 17 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR17; 2-Acetylaminofluorene results in increased expression of MIR17 mRNA CTD PMID:19167416 PMID:20188851 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir181b2 microRNA 181b-2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR181B-2 mRNA CTD PMID:19167416 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035
JBrowse link
G Mir181c microRNA 181c decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR181C mRNA CTD PMID:19167416 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir185 microRNA 185 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR185 mRNA CTD PMID:19167416 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir18a microRNA 18a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR18A; 2-Acetylaminofluorene results in increased expression of MIR18A mRNA CTD PMID:19167416 PMID:20188851 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir200a microRNA 200a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200A mRNA CTD PMID:19167416 PMID:22584684 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir200b microRNA 200b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200B mRNA CTD PMID:19167416 PMID:22584684 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir200c microRNA 200c increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200C mRNA CTD PMID:19167416 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir202 microRNA 202 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR202 mRNA CTD PMID:19167416 NCBI chr 1:194,754,730...194,754,801
Ensembl chr 1:194,754,730...194,754,801
JBrowse link
G Mir204 microRNA 204 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR204 mRNA CTD PMID:19167416 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mir205 microRNA 205 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR205 mRNA CTD PMID:19167416 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir20a microRNA 20a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR20A; 2-Acetylaminofluorene results in increased expression of MIR20A mRNA CTD PMID:19167416 PMID:20188851 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir21 microRNA 21 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR21 mRNA CTD PMID:19167416 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir22 microRNA 22 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR22 mRNA CTD PMID:22213190 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
JBrowse link
G Mir221 microRNA 221 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR221 mRNA CTD PMID:19167416 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir31 microRNA 31 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR31; 2-Acetylaminofluorene results in increased expression of MIR31 mRNA CTD PMID:19167416 PMID:20188851 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir34a microRNA 34a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR34A mRNA CTD PMID:19167416 PMID:22584684 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir3545 microRNA 3545 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR203 mRNA CTD PMID:22584684 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
JBrowse link
G Mir410 microRNA 410 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR410 mRNA CTD PMID:19167416 NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434
JBrowse link
G Mir429 microRNA 429 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR429 mRNA CTD PMID:19167416 PMID:22584684 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
JBrowse link
G Mir490 microRNA 490 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR490 mRNA CTD PMID:19167416 NCBI chr 4:65,047,548...65,047,631
Ensembl chr 4:65,047,548...65,047,631
JBrowse link
G Mir93 microRNA 93 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR93; 2-Acetylaminofluorene results in increased expression of MIR93 mRNA CTD PMID:19167416 PMID:20188851 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mir96 microRNA 96 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR96 mRNA CTD PMID:19167416 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mir99a microRNA 99a decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR99A mRNA CTD PMID:19167416 PMID:22584684 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7B mRNA CTD PMID:19167416 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7C-1 mRNA CTD PMID:19167416 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Mirlet7i microRNA let-7i increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7I mRNA CTD PMID:19167416 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein]; Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]
2-Acetylaminofluorene results in increased expression of MKI67 mRNA
CTD PMID:15565650 PMID:17317680 PMID:17393424 PMID:23665045 PMID:26338220 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MMP2 mRNA CTD PMID:18678246 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP 2-Acetylaminofluorene results in increased expression of MMP9 mRNA CTD PMID:18678246 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
EXP Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein] CTD PMID:15565650 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mthfr methylenetetrahydrofolate reductase decreases expression
decreases methylation
EXP 2-Acetylaminofluorene results in decreased expression of MTHFR mRNA
2-Acetylaminofluorene results in decreased methylation of MTHFR promoter
CTD PMID:22213190 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression EXP 2-Acetylaminofluorene results in increased expression of MUC1 mRNA CTD PMID:17187413 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of MYBL1 mRNA CTD PMID:21607683 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases mutagenesis
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MYC protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MYC protein]
2-Acetylaminofluorene results in increased mutagenesis of MYC gene
2-Acetylaminofluorene results in increased expression of MYC protein
CTD PMID:11350689 PMID:17696247 PMID:19167416 PMID:20188851 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of NAMPT mRNA CTD PMID:22584684 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nat1 N-acetyltransferase 1 increases activity ISO NAT1 protein results in increased activity of 2-Acetylaminofluorene CTD PMID:15450435 NCBI chr16:22,218,217...22,238,516 JBrowse link
G Nat2 N-acetyltransferase 2 increases activity ISO NAT2 protein results in increased activity of 2-Acetylaminofluorene CTD PMID:15450435 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nek6 NIMA-related kinase 6 increases expression EXP 2-Acetylaminofluorene results in increased expression of NEK6 mRNA CTD PMID:22584684 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
increases activity
ISO 2-Acetylaminofluorene results in increased expression of NFE2L2 mRNA
2-Acetylaminofluorene results in increased activity of NFE2L2 protein
CTD PMID:21607683 PMID:30114225 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases localization
ISO [RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
2-Acetylaminofluorene results in increased localization of NFKB1 protein
Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased localization of NFKB1 protein]
CTD PMID:11960367 PMID:17303067 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein; Acetylcysteine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]; S-Adenosylmethionine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein] CTD PMID:18404532 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions
increases degradation
EXP [2-Acetylaminofluorene results in increased abundance of Reactive Oxygen Species] which results in increased degradation of NFKBIB protein
2-Acetylaminofluorene results in increased degradation of NFKBIB protein
CTD PMID:11020383 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Ninj1 ninjurin 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NINJ1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein] CTD PMID:23665045 PMID:26364502 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of NOS3 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of NOS3 mRNA]
CTD PMID:17317680 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of NOTCH1 mRNA CTD PMID:21607683 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit increases expression ISO 2-Acetylaminofluorene results in increased expression of NPRL2 mRNA CTD PMID:17317680 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of NQO1 mRNA CTD PMID:21607683 PMID:22213190 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of NR1I2 mRNA
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A11 mRNA]
CTD PMID:12504080 PMID:16381673 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nudcd2 NudC domain containing 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of NUDCD2 mRNA CTD PMID:21607683 NCBI chr10:25,163,247...25,168,738
Ensembl chr10:25,163,220...25,168,738
JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of NUDT7 mRNA CTD PMID:21607683 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-Acetylaminofluorene results in decreased expression of NUPR1 mRNA CTD PMID:17070881 PMID:22584684 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of NUSAP1 mRNA CTD PMID:22584684 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Ociad2 OCIA domain containing 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of OCIAD2 mRNA CTD PMID:17317680 NCBI chr14:34,873,668...34,889,276
Ensembl chr14:34,873,820...34,889,265
JBrowse link
G Olfm1 olfactomedin 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of OLFM1 mRNA CTD PMID:20713471 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184 JBrowse link
G Osm oncostatin M increases expression EXP 2-Acetylaminofluorene results in increased expression of OSM mRNA CTD PMID:15743783 PMID:18678246 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Osmr oncostatin M receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of OSMR mRNA CTD PMID:15743783 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G Padi2 peptidyl arginine deiminase 2 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PADI2 mRNA] CTD PMID:17317680 NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PCK1 mRNA CTD PMID:16510358 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein] CTD PMID:16352317 PMID:17393424 PMID:19167416 PMID:23665045 PMID:26364502 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PDIA3 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PDIA3 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PECAM1 mRNA CTD PMID:17187413 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Perp p53 apoptosis effector related to PMP22 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PERP mRNA] CTD PMID:17317680 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of PHLDA3 mRNA CTD PMID:17070881 PMID:21607683 PMID:22584684 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of PHYH mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of PHYH mRNA CTD PMID:14656948 PMID:16158176 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis EXP 2-Acetylaminofluorene results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PKD1 mRNA CTD PMID:22584684 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP 2-Acetylaminofluorene results in increased expression of PKM mRNA; 2-Acetylaminofluorene results in increased expression of PKM protein CTD PMID:17538966 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pkp1 plakophilin 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of PKP1 mRNA CTD PMID:17317680 NCBI chr13:47,309,603...47,357,551
Ensembl chr13:47,309,614...47,357,465
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of PLK2 mRNA CTD PMID:21607683 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA]
CTD PMID:17317680 PMID:19167416 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Polk DNA polymerase kappa increases expression ISO 2-Acetylaminofluorene results in increased expression of POLK mRNA CTD PMID:21607683 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP 2-Acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PRC1 mRNA CTD PMID:19167416 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prkch protein kinase C, eta multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PRKCH mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PRKCH mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prom1 prominin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PROM1 mRNA CTD PMID:17187413 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prox1 prospero homeobox 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PROX1 mRNA CTD PMID:22213190 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of PSMD10 protein
RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein]
CTD PMID:16448463 NCBI chr  X:104,656,809...104,665,126 JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of PSRC1 mRNA CTD PMID:21607683 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
JBrowse link
G Pten phosphatase and tensin homolog decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PTEN protein CTD PMID:19167416 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PTGR1 mRNA CTD PMID:16158176 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein] CTD PMID:23665045 PMID:26364502 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptn pleiotrophin increases expression EXP 2-Acetylaminofluorene results in increased expression of PTN mRNA CTD PMID:12057922 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 increases expression ISO 2-Acetylaminofluorene results in increased expression of PTP4A3 mRNA CTD PMID:17317680 NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression EXP 2-Acetylaminofluorene results in increased expression of PTPRC mRNA CTD PMID:17187413 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression EXP 2-Acetylaminofluorene results in increased expression of PTTG1 mRNA CTD PMID:19167416 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Pvt1 Pvt1 oncogene increases expression ISO 2-Acetylaminofluorene results in increased expression of PVT1 mRNA CTD PMID:21607683 NCBI chr 7:93,656,249...93,879,938 JBrowse link
G Rac1 Rac family small GTPase 1 increases activity
multiple interactions
ISO 2-Acetylaminofluorene results in increased activity of RAC1 protein
[2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA
CTD PMID:11960367 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rassf1 Ras association domain family member 1 increases methylation EXP 2-Acetylaminofluorene results in increased methylation of RASSF1 promoter CTD PMID:20188851 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation
multiple interactions
EXP 2-Acetylaminofluorene affects the phosphorylation of RB1 protein
2-Acetylaminofluorene results in increased expression of and results in increased phosphorylation of RB1 protein; RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein]
CTD PMID:15158336 PMID:16448463 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbx1 ring-box 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of RBX1 mRNA CTD PMID:17317680 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
increases expression
multiple interactions
increases localization
ISO
EXP
2-Acetylaminofluorene results in increased activity of RELA protein
2-Acetylaminofluorene results in increased expression of RELA protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; RELA protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]
2-Acetylaminofluorene results in increased localization of RELA protein
[RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
2-Acetylaminofluorene inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased localization of RELA protein]
CTD PMID:11020383 PMID:11960367 PMID:14670622 PMID:17303067 PMID:26364502 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rgn regucalcin multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of RGN mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of RGN mRNA CTD PMID:14656948 PMID:16158176 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of RGS2 mRNA CTD PMID:22584684 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of RHBDF2 mRNA CTD PMID:21607683 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
JBrowse link
G Rhob ras homolog family member B increases expression EXP 2-Acetylaminofluorene results in increased expression of RHOB mRNA CTD PMID:22584684 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of RIPK1 mRNA CTD PMID:22584684 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of RIPK3 mRNA CTD PMID:17317680 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Ripk4 receptor-interacting serine-threonine kinase 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of RIPK4 mRNA CTD PMID:21607683 NCBI chr11:37,122,555...37,144,799
Ensembl chr11:37,122,565...37,144,799
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of ROS1 mRNA CTD PMID:17187413 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of RPLP0 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of RPLP0 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog multiple interactions
increases expression
decreases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of RPRM mRNA]
2-Acetylaminofluorene results in increased expression of RPRM mRNA
2-Acetylaminofluorene results in decreased expression of RPRM mRNA
CTD PMID:17317680 PMID:19167416 PMID:22584684 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO 2-Acetylaminofluorene results in increased expression of RPS27L mRNA CTD PMID:17317680 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO 2-Acetylaminofluorene results in increased expression of RRM1 mRNA CTD PMID:17317680 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO 2-Acetylaminofluorene results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of RSAD2 mRNA CTD PMID:20713471 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO 2-Acetylaminofluorene results in increased expression of S100A11 mRNA CTD PMID:17317680 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a14 S100 calcium binding protein A14 increases expression ISO 2-Acetylaminofluorene results in increased expression of S100A14 mRNA CTD PMID:17317680 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423
JBrowse link
G Scarb2 scavenger receptor class B, member 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SCARB2 mRNA CTD PMID:17317680 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
JBrowse link
G Scpep1 serine carboxypeptidase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of SCPEP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of SCPEP1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Sctr secretin receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of SCTR mRNA CTD PMID:17187413 NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Serpinb5 serpin family B member 5 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of SERPINB5 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of SERPINB5 mRNA]
CTD PMID:17317680 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SERPINF1 mRNA CTD PMID:21607683 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sesn2 sestrin 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SESN2 mRNA CTD PMID:21607683 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfn stratifin increases expression EXP 2-Acetylaminofluorene results in increased expression of SFN mRNA CTD PMID:19167416 PMID:22213190 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sirt1 sirtuin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SIRT1 protein CTD PMID:19167416 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc15a5 solute carrier family 15, member 5 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SLC15A5 mRNA CTD PMID:21607683 NCBI chr 4:170,878,021...170,971,620
Ensembl chr 4:170,878,021...170,971,620
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of SLC25A4 mRNA] CTD PMID:17317680 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc2a8 solute carrier family 2 member 8 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SLC2A8 mRNA] CTD PMID:17317680 NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SLC40A1 mRNA CTD PMID:21785164 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SLCO1A4 mRNA CTD PMID:16158176 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SLCO1B2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of SLCO1B2 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Smad2 SMAD family member 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein] CTD PMID:15368444 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] CTD PMID:15368444 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SMAD4 mRNA CTD PMID:22213190 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smo smoothened, frizzled class receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of SMO mRNA CTD PMID:17187413 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Sncg synuclein, gamma increases expression EXP 2-Acetylaminofluorene results in increased expression of SNCG mRNA CTD PMID:22213190 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Sntg2 syntrophin, gamma 2 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SNTG2 mRNA CTD PMID:21607683 NCBI chr 6:46,801,377...47,003,424
Ensembl chr 6:46,801,377...47,003,372
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SOCS1 mRNA CTD PMID:22213190 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of SOD1 protein CTD PMID:17761372 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of and results in increased activity of SOD2 protein; O-(Chloroacetylcarbamoyl)fumagillol inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of and results in increased activity of SOD2 protein] CTD PMID:17761372 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression EXP 2-Acetylaminofluorene results in increased expression of SOX4 mRNA CTD PMID:22584684 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Spg7 SPG7 matrix AAA peptidase subunit, paraplegin multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of SPG7 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of SPG7 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr19:51,117,045...51,151,228
Ensembl chr19:51,117,057...51,150,484
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO 2-Acetylaminofluorene results in increased expression of SPRR1A mRNA CTD PMID:17317680 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr2f small proline rich protein 2F increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of SPRR2F mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SPRR2F mRNA]
CTD PMID:17317680 NCBI chr 2:177,989,974...177,990,204 JBrowse link
G Sprr2g small proline rich protein 2G increases expression ISO 2-Acetylaminofluorene results in increased expression of SPRR2G mRNA CTD PMID:17317680
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SPTLC2 mRNA CTD PMID:17317680 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Sst somatostatin increases expression EXP 2-Acetylaminofluorene results in increased expression of SST protein CTD PMID:16534498 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of ST3GAL3 mRNA CTD PMID:21607683 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of ST3GAL5 protein CTD PMID:6331524 NCBI chr 4:104,134,553...104,192,560
Ensembl chr 4:104,134,613...104,192,558
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein; Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Steap3 STEAP3 metalloreductase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of STEAP3 mRNA CTD PMID:22584684 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Stmn1 stathmin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of STMN1 mRNA CTD PMID:22584684 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sulf2 sulfatase 2 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of SULF2 mRNA CTD PMID:17070881 PMID:21607683 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SULT1C2 mRNA CTD PMID:21607683 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of SULT1E1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Taldo1 transaldolase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TALDO1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TALDO1 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tceal9 transcription elongation factor A like 9 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TCEAL9 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TCEAL9 mRNA CTD PMID:14656948 PMID:16158176 NCBI chr  X:99,245,645...99,247,715
Ensembl chr  X:99,228,458...99,247,763
JBrowse link
G Tes testin LIM domain protein increases expression EXP 2-Acetylaminofluorene results in increased expression of TES mRNA CTD PMID:21784091 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
JBrowse link
G Tf transferrin decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TF mRNA CTD PMID:16510358 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TFF1 mRNA] CTD PMID:17317680 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tff3 trefoil factor 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of TFF3 mRNA CTD PMID:22213190 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
JBrowse link
G Tfrc transferrin receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of TFRC mRNA CTD PMID:21785164 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein]
2-Acetylaminofluorene results in increased expression of TGFB1 mRNA
CTD PMID:15368444 PMID:15940639 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thrb thyroid hormone receptor beta increases activity ISO 2-Acetylaminofluorene results in increased activity of THRB protein CTD PMID:31077750 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression EXP 2-Acetylaminofluorene results in increased expression of THY1 protein CTD PMID:17576600 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of TIMP1 mRNA CTD PMID:18678246 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tkt transketolase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TKT mRNA CTD PMID:14656948 PMID:16158176 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tmem134 transmembrane protein 134 increases expression ISO 2-Acetylaminofluorene results in increased expression of TMEM134 mRNA CTD PMID:17317680 NCBI chr 1:201,419,225...201,424,778
Ensembl chr 1:201,419,264...201,431,411
JBrowse link
G Tmem184c transmembrane protein 184C increases expression EXP 2-Acetylaminofluorene results in increased expression of TMEM184C mRNA CTD PMID:21784091 NCBI chr19:30,345,183...30,361,275
Ensembl chr19:30,345,290...30,361,269
JBrowse link
G Tmem43 transmembrane protein 43 increases expression ISO 2-Acetylaminofluorene results in increased expression of TMEM43 mRNA CTD PMID:21607683 NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TNF protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of TNF protein] CTD PMID:18271918 PMID:23665045 PMID:25051504 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO 2-Acetylaminofluorene results in increased expression of TNFRSF10B mRNA CTD PMID:21607683 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP 2-Acetylaminofluorene results in increased expression of TOP2A mRNA CTD PMID:22584684 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
increases response to substance
multiple interactions
EXP
ISO
2-Acetylaminofluorene results in increased expression of TP53 protein
2-Acetylaminofluorene results in increased expression of TRP53 protein
2-Acetylaminofluorene results in decreased expression of TP53 protein
TRP53 protein modified form results in increased susceptibility to 2-Acetylaminofluorene
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of BAX mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CCNB2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CDKN1A mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of EI24 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PERP mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of RPRM mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of SERPINB5 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of ZMAT3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of CYP4F15 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of MEG3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of SLC25A4 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of TTR mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ALDH3A1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ANXA3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of AREG mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of COL17A1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of HEBP2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT15 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT23 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT4 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of LYPD3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of NOS3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PADI2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SLC2A8 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SPRR2F mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TFF1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TSHB mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TUBA1C mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of UBE2C mRNA]
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of TP53 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TP53 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]; Vanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein]
CTD PMID:7728945 PMID:9667752 PMID:10708481 PMID:11003613 PMID:11915028 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 multiple interactions
increases expression
EXP
ISO
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of TRP53INP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TRP53INP1 mRNA
2-Acetylaminofluorene results in increased expression of TP53INP1 mRNA
2-Acetylaminofluorene results in increased expression of TRP53INP1 mRNA
CTD PMID:14656948 PMID:16158176 PMID:21607683 PMID:22584684 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tp73 tumor protein p73 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TP73 mRNA CTD PMID:22213190 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TRPM2 mRNA CTD PMID:16158176 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TSHB mRNA] CTD PMID:17317680 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Ttr transthyretin multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of TTR mRNA] CTD PMID:17317680 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tuba1c tubulin, alpha 1C multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TUBA1C mRNA] CTD PMID:17317680 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb4b tubulin, beta 4B class IVb increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of TUBB4B mRNA CTD PMID:21607683 PMID:22584684 NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 2-Acetylaminofluorene results in increased expression of TUBB5 mRNA CTD PMID:22584684 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression ISO 2-Acetylaminofluorene results in increased expression of TUBB6 mRNA CTD PMID:21607683 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of UBE2C mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of UBE2C mRNA]
CTD PMID:17317680 PMID:22584684 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2-Acetylaminofluorene analog CTD PMID:11375903 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of VCAM1 mRNA
2-Acetylaminofluorene results in increased expression of VCAM1 protein
CTD PMID:21607683 PMID:25051504 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of VEGFA mRNA
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein]
CTD PMID:22213190 PMID:25051504 PMID:26364502 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of WEE1 mRNA CTD PMID:22584684 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO 2-Acetylaminofluorene results in decreased expression of WWOX mRNA CTD PMID:21607683 NCBI chr19:42,432,141...43,360,278 JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions
EXP 2-Acetylaminofluorene results in increased activity of XDH protein
Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein]
CTD PMID:23665045 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases response to substance ISO XPC protein results in decreased susceptibility to 2-Acetylaminofluorene CTD PMID:23153559 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ZEB1 protein CTD PMID:19167416 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ZEB2 protein CTD PMID:19167416 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
G Zmat3 zinc finger, matrin type 3 multiple interactions
increases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of ZMAT3 mRNA]
2-Acetylaminofluorene results in increased expression of ZMAT3 mRNA
CTD PMID:17070881 PMID:17317680 PMID:19167416 PMID:21607683 PMID:22584684 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
2-nitrofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP 2-nitrofluorene results in increased expression of ABCB1A mRNA CTD PMID:22484513 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 2-nitrofluorene results in increased expression of ABCB1B mRNA CTD PMID:14600272 PMID:23052194 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP 2-nitrofluorene results in increased expression of ABCC3 mRNA CTD PMID:23052194 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Aco1 aconitase 1 increases expression EXP 2-nitrofluorene results in increased expression of ACO1 mRNA CTD PMID:15890375 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 2-nitrofluorene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of AIF1 mRNA CTD PMID:14600272 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-nitrofluorene results in increased expression of AKR7A3 mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-nitrofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Anxa2 annexin A2 increases expression EXP 2-nitrofluorene results in increased expression of ANXA2 mRNA CTD PMID:14600272 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP 2-nitrofluorene results in increased expression of APEX1 mRNA CTD PMID:15890375 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP 2-nitrofluorene results in increased expression of ARPC1B mRNA CTD PMID:14600272 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP 2-nitrofluorene results in increased expression of ATF3 mRNA CTD PMID:15890375 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 decreases expression EXP 2-nitrofluorene results in decreased expression of ATP5MC1 mRNA CTD PMID:14600272 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-nitrofluorene results in increased expression of ATP6V1D mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 2-nitrofluorene results in increased expression of BAX mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of BHMT mRNA CTD PMID:14600272 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of BTG2 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression EXP 2-nitrofluorene results in increased expression of CCDC86 mRNA CTD PMID:22484513 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP 2-nitrofluorene results in increased expression of CCNB1 mRNA CTD PMID:15890375 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP 2-nitrofluorene results in increased expression of CCND1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 2-nitrofluorene results in increased expression of CCNG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of CCT3 mRNA CTD PMID:15890375 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression EXP 2-nitrofluorene results in decreased expression of CD1D1 mRNA CTD PMID:22484513 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd74 CD74 molecule increases expression EXP 2-nitrofluorene results in increased expression of CD74 mRNA CTD PMID:14600272 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP 2-nitrofluorene results in decreased expression of CDC20 mRNA CTD PMID:15890375 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP 2-nitrofluorene results in increased expression of CDK1 mRNA CTD PMID:15890375 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk16 cyclin-dependent kinase 16 increases expression EXP 2-nitrofluorene results in increased expression of CDK16 mRNA CTD PMID:15890375 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP 2-nitrofluorene results in increased expression of CDK4 mRNA CTD PMID:15890375 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP 2-nitrofluorene results in increased expression of CDKN1A mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP 2-nitrofluorene results in increased expression of CES2C mRNA CTD PMID:23052194 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP 2-nitrofluorene results in increased expression of CES2 mRNA CTD PMID:14600272 PMID:22484513 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGREF1 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGRRF1 mRNA CTD PMID:15890375 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression EXP 2-nitrofluorene results in increased expression of CR1L mRNA CTD PMID:15890375 PMID:22484513 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-nitrofluorene results in increased expression of CRYAB mRNA CTD PMID:14600272 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cstb cystatin B increases expression EXP 2-nitrofluorene results in increased expression of CSTB mRNA CTD PMID:15890375 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctsd cathepsin D increases expression EXP 2-nitrofluorene results in increased expression of CTSD mRNA CTD PMID:15890375 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctss cathepsin S increases expression EXP 2-nitrofluorene results in increased expression of CTSS mRNA CTD PMID:14600272 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP 2-nitrofluorene results in increased expression of CXCL10 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects expression EXP 2-nitrofluorene affects the expression of CXCL3 mRNA CTD PMID:22484513 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP 2-nitrofluorene results in decreased expression of CYB5R3 mRNA CTD PMID:14600272 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2-nitrofluorene results in increased expression of CYP1A1 mRNA CTD PMID:23052194 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of CYP2C12 mRNA
2-nitrofluorene results in increased expression of CYP2C12 mRNA
CTD PMID:23052194 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Dcn decorin increases expression EXP 2-nitrofluorene results in increased expression of DCN mRNA CTD PMID:14600272 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of DDAH1 mRNA CTD PMID:15890375 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddx21 DExD-box helicase 21 increases expression EXP 2-nitrofluorene results in increased expression of DDX21 mRNA CTD PMID:15890375 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression EXP 2-nitrofluorene results in decreased expression of DKC1 mRNA CTD PMID:15890375
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP 2-nitrofluorene results in increased expression of DMBT1 mRNA CTD PMID:23052194 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of DPYD mRNA CTD PMID:15890375 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dus1l dihydrouridine synthase 1-like increases expression EXP 2-nitrofluorene results in increased expression of DUS1L mRNA CTD PMID:22484513 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of DUSP6 mRNA CTD PMID:15890375 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP 2-nitrofluorene results in increased expression of DUT mRNA CTD PMID:15890375 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression EXP 2-nitrofluorene results in increased expression of EEF1G mRNA CTD PMID:15890375 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of EEF2 mRNA CTD PMID:15890375 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of EIF4EBP1 mRNA CTD PMID:15890375 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression EXP 2-nitrofluorene results in increased expression of FAM162A mRNA CTD PMID:15890375 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Fcgr2a Fc gamma receptor IIa increases expression EXP 2-nitrofluorene results in increased expression of FCGR3 mRNA CTD PMID:14600272 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression EXP 2-nitrofluorene results in increased expression of FKBP4 mRNA CTD PMID:15890375 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fn1 fibronectin 1 decreases expression EXP 2-nitrofluorene results in decreased expression of FN1 mRNA CTD PMID:15890375 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2-nitrofluorene results in increased expression of GADD45A mRNA CTD PMID:15890375 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas6 growth arrest specific 6 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of GAS6 mRNA
2-nitrofluorene results in increased expression of GAS6 mRNA
CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP 2-nitrofluorene results in increased expression of GCLC mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 2-nitrofluorene results in increased expression of GDF15 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gls2 glutaminase 2 decreases expression EXP 2-nitrofluorene results in decreased expression of GLS2 mRNA CTD PMID:14600272 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of GNMT mRNA CTD PMID:14600272 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gpr108 G protein-coupled receptor 108 decreases expression EXP 2-nitrofluorene results in decreased expression of GPR108 mRNA CTD PMID:22484513 NCBI chr 9:2,120,740...2,131,771
Ensembl chr 9:2,120,744...2,132,572
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of GRIA3 mRNA CTD PMID:22484513 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP 2-nitrofluorene results in increased expression of GRPEL1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP 2-nitrofluorene results in increased expression of GSR mRNA CTD PMID:14600272 PMID:15890375 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression EXP 2-nitrofluorene results in increased expression of GSS mRNA CTD PMID:15890375 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of GSTA2 mRNA CTD PMID:15890375 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of GSTA5 mRNA CTD PMID:14600272 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2-nitrofluorene results in increased expression of GSTP1 mRNA CTD PMID:23052194 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H2ax H2A.X variant histone increases expression EXP 2-nitrofluorene results in increased expression of H2AX mRNA CTD PMID:15890375 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP 2-nitrofluorene results in increased expression of H2AZ1 mRNA CTD PMID:15890375 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G Hdc histidine decarboxylase increases expression EXP 2-nitrofluorene results in increased expression of HDC mRNA CTD PMID:15890375 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression EXP 2-nitrofluorene results in increased expression of HECTD1 mRNA CTD PMID:22484513 NCBI chr 6:69,181,429...69,267,803
Ensembl chr 6:69,181,436...69,268,053
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP 2-nitrofluorene results in increased expression of HMGB2 mRNA CTD PMID:15890375 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP 2-nitrofluorene results in increased expression of HMOX1 mRNA CTD PMID:15890375 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP 2-nitrofluorene results in increased expression of HSF1 mRNA CTD PMID:15890375 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP 2-nitrofluorene results in increased expression of HSPA9 mRNA CTD PMID:15890375 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPB1 mRNA CTD PMID:15890375 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPE1 mRNA CTD PMID:15890375 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPH1 mRNA CTD PMID:15890375 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ide insulin degrading enzyme increases expression EXP 2-nitrofluorene results in increased expression of IDE mRNA CTD PMID:15890375 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of IGFBP1 mRNA CTD PMID:15890375 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 2-nitrofluorene results in decreased expression of IGFBP3 mRNA CTD PMID:15890375 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of IRF1 mRNA CTD PMID:14600272 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of LAMA5 mRNA CTD PMID:22484513 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
JBrowse link
G Lgals3 galectin 3 increases expression EXP 2-nitrofluorene results in increased expression of LGALS3 mRNA CTD PMID:15890375 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of MAP2K6 mRNA CTD PMID:22484513 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression EXP 2-nitrofluorene results in decreased expression of MAT1A mRNA CTD PMID:14600272 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP 2-nitrofluorene results in increased expression of MCM6 mRNA CTD PMID:15890375 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP 2-nitrofluorene results in increased expression of MDM2 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 2-nitrofluorene results in increased expression of MGMT mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 2-nitrofluorene results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A decreases expression EXP 2-nitrofluorene results in decreased expression of MT2 mRNA; 2-nitrofluorene results in decreased expression of MT2A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP 2-nitrofluorene results in increased expression of MYC mRNA CTD PMID:15890375 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Naglt1 Na+ dependent glucose transporter 1 affects expression EXP 2-nitrofluorene affects the expression of NAGLT1 mRNA CTD PMID:22484513 NCBI chr20:43,411,550...43,423,873
Ensembl chr20:43,394,843...43,423,873
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP 2-nitrofluorene results in increased expression of NAP1L1 mRNA CTD PMID:15890375 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 increases expression EXP 2-nitrofluorene results in increased expression of NHEJ1 mRNA CTD PMID:22484513 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP 2-nitrofluorene results in increased expression of NPM1 mRNA CTD PMID:15890375 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP 2-nitrofluorene results in increased expression of NQO1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP 2-nitrofluorene results in increased expression of NRG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-nitrofluorene results in decreased expression of NUPR1 mRNA CTD PMID:15890375 PMID:23052194 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oat ornithine aminotransferase decreases expression EXP 2-nitrofluorene results in decreased expression of OAT mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Obp3 alpha-2u globulin PGCL4 decreases expression EXP 2-nitrofluorene results in decreased expression of OBP3 mRNA CTD PMID:15890375 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP 2-nitrofluorene results in increased expression of ODC1 mRNA CTD PMID:15890375 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-nitrofluorene results in increased expression of PCNA mRNA CTD PMID:15890375 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO 2-nitrofluorene results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of PHGDH mRNA CTD PMID:15890375 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP 2-nitrofluorene results in increased expression of PHLDA3 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pmm1 phosphomannomutase 1 increases expression EXP 2-nitrofluorene results in increased expression of PMM1 mRNA CTD PMID:22484513 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMA1 mRNA CTD PMID:15890375 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMA2 mRNA CTD PMID:15890375 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMA4 mRNA CTD PMID:15890375 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMA5 mRNA CTD PMID:15890375 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 increases expression EXP 2-nitrofluorene results in increased expression of PSMA7 mRNA CTD PMID:15890375 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMB1 mRNA CTD PMID:15890375 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression EXP 2-nitrofluorene results in increased expression of PSMB3 mRNA CTD PMID:15890375 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMB4 mRNA CTD PMID:15890375 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMB5 mRNA CTD PMID:15890375 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP 2-nitrofluorene results in increased expression of PSMB8 mRNA CTD PMID:14600272 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP 2-nitrofluorene results in increased expression of PSMB9 mRNA CTD PMID:14600272 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMC1 mRNA CTD PMID:15890375 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMC2 mRNA CTD PMID:15890375 NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMC4 mRNA CTD PMID:15890375 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMC5 mRNA CTD PMID:15890375 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMD1 mRNA CTD PMID:15890375 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP 2-nitrofluorene results in increased expression of PTP4A1 mRNA CTD PMID:15890375 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP 2-nitrofluorene results in decreased expression of PTTG1 mRNA CTD PMID:15890375 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP 2-nitrofluorene results in decreased expression of RB1 mRNA CTD PMID:15890375 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP 2-nitrofluorene results in increased expression of RHEB mRNA CTD PMID:15890375 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rhob ras homolog family member B increases expression EXP 2-nitrofluorene results in increased expression of RHOB mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rpl10 ribosomal protein L10 increases expression EXP 2-nitrofluorene results in increased expression of RPL10 mRNA CTD PMID:15890375 NCBI chr  X:152,054,547...152,056,757
Ensembl chr  X:152,054,452...152,056,761
JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP 2-nitrofluorene results in increased expression of RPL10A mRNA CTD PMID:15890375 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP 2-nitrofluorene results in increased expression of RPL13 mRNA CTD PMID:15890375 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl15 ribosomal protein L15 increases expression EXP 2-nitrofluorene results in increased expression of RPL15 mRNA CTD PMID:15890375 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 increases expression EXP 2-nitrofluorene results in increased expression of RPL17 mRNA CTD PMID:15890375 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl23 ribosomal protein L23 increases expression EXP 2-nitrofluorene results in increased expression of RPL23 mRNA CTD PMID:15890375 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 2-nitrofluorene results in increased expression of RPL6 mRNA CTD PMID:15890375 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rpl7a ribosomal protein L7a increases expression EXP 2-nitrofluorene results in increased expression of RPL7A mRNA CTD PMID:15890375 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP 2-nitrofluorene results in increased expression of RPL8 mRNA CTD PMID:15890375 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rps15a ribosomal protein S15a increases expression EXP 2-nitrofluorene results in increased expression of RPS15A mRNA CTD PMID:15890375 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995
JBrowse link
G Rps19 ribosomal protein S19 increases expression EXP 2-nitrofluorene results in increased expression of RPS19 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps24 ribosomal protein S24 increases expression EXP 2-nitrofluorene results in increased expression of RPS24 mRNA CTD PMID:15890375 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
JBrowse link
G Rps27l ribosomal protein S27-like increases expression EXP 2-nitrofluorene results in increased expression of RPS27L mRNA CTD PMID:15890375 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP 2-nitrofluorene results in increased expression of RPS3 mRNA CTD PMID:15890375 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps4x ribosomal protein S4, X-linked increases expression EXP 2-nitrofluorene results in increased expression of RPS4X mRNA CTD PMID:15890375 NCBI chr  X:67,298,522...67,302,965
Ensembl chr  X:67,298,525...67,303,019
JBrowse link
G Rps7 ribosomal protein S7 increases expression EXP 2-nitrofluorene results in increased expression of RPS7 mRNA CTD PMID:15890375 NCBI chr 6:45,266,200...45,271,064 JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 2-nitrofluorene results in increased expression of RPSA mRNA CTD PMID:15890375 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression EXP 2-nitrofluorene results in decreased expression of RSAD2 mRNA CTD PMID:22484513 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression EXP 2-nitrofluorene results in increased expression of RT1-BB mRNA CTD PMID:14600272 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Da RT1 class II, locus Da increases expression EXP 2-nitrofluorene results in increased expression of RT1-DA mRNA CTD PMID:14600272 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP 2-nitrofluorene results in increased expression of RT1-EC2 mRNA CTD PMID:14600272
G Sds serine dehydratase decreases expression EXP 2-nitrofluorene results in decreased expression of SDS mRNA CTD PMID:14600272 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Selenow selenoprotein W increases expression EXP 2-nitrofluorene results in increased expression of SELENOW mRNA CTD PMID:15890375 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-nitrofluorene results in increased expression of SERPINA7 mRNA CTD PMID:14600272 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP 2-nitrofluorene results in increased expression of SPTAN1 mRNA CTD PMID:14600272 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression EXP 2-nitrofluorene results in increased expression of STAT1 mRNA CTD PMID:14600272 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stmn1 stathmin 1 increases expression EXP 2-nitrofluorene results in increased expression of STMN1 mRNA CTD PMID:15890375 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP 2-nitrofluorene results in increased expression of TAP1 mRNA CTD PMID:14600272 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tat tyrosine aminotransferase increases expression EXP 2-nitrofluorene results in increased expression of TAT mRNA CTD PMID:15890375 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression EXP 2-nitrofluorene results in increased expression of TIMM10B mRNA CTD PMID:15890375 NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2-nitrofluorene results in increased expression of TIMP1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression EXP 2-nitrofluorene results in increased expression of TMSB10 mRNA CTD PMID:14600272 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TNFAIP3 mRNA
2-nitrofluorene results in increased expression of TNFAIP3 mRNA
CTD PMID:21873647 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP 2-nitrofluorene results in increased expression of TOP2A mRNA CTD PMID:15890375 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TPD52 mRNA
2-nitrofluorene results in increased expression of TPD52 mRNA
CTD PMID:21873647 NCBI chr 2:92,735,246...92,816,079
Ensembl chr 2:92,735,620...92,816,622
JBrowse link
G Trappc10 trafficking protein particle complex subunit 10 increases expression EXP 2-nitrofluorene results in increased expression of TRAPPC10 mRNA CTD PMID:22484513 NCBI chr20:10,438,737...10,499,074
Ensembl chr20:10,438,737...10,499,074
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 2-nitrofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15890375 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Tuba1c tubulin, alpha 1C increases expression EXP 2-nitrofluorene results in increased expression of TUBA1C mRNA CTD PMID:15890375 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 2-nitrofluorene results in increased expression of TUBB5 mRNA CTD PMID:15890375 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tyms thymidylate synthetase increases expression EXP 2-nitrofluorene results in increased expression of TYMS mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases expression EXP 2-nitrofluorene results in increased expression of UGT1A7 mRNA CTD PMID:14600272 NCBI chr 9:88,739,577...88,808,465 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP 2-nitrofluorene results in increased expression of UGT2B17 mRNA CTD PMID:23052194 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP 2-nitrofluorene results in increased expression of VEGFA mRNA CTD PMID:15890375 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin increases expression EXP 2-nitrofluorene results in increased expression of VIM mRNA CTD PMID:14600272 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xdh xanthine dehydrogenase decreases expression
increases reduction
EXP
ISO
2-nitrofluorene results in decreased expression of XDH mRNA
XDH protein results in increased reduction of 2-nitrofluorene
CTD PMID:15890375 PMID:15932950 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 2-nitrofluorene results in increased expression of ZMAT3 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
4-acetylaminofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 4-acetylaminofluorene results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP 4-acetylaminofluorene results in increased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 4-acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression EXP 4-acetylaminofluorene results in decreased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 4-acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 4-acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 4-acetylaminofluorene results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C7 complement C7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 4-acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 4-acetylaminofluorene results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 4-acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 4-acetylaminofluorene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 4-acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 4-acetylaminofluorene results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 4-acetylaminofluorene results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 4-acetylaminofluorene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 4-acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor increases expression
decreases expression
EXP 4-acetylaminofluorene results in increased expression of FAS mRNA
4-acetylaminofluorene results in decreased expression of FAS mRNA
CTD PMID:17070881 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 4-acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 4-acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 increases expression EXP 4-acetylaminofluorene results in increased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 4-acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 4-acetylaminofluorene results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 4-acetylaminofluorene results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 4-acetylaminofluorene results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP 4-acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 4-acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP 4-acetylaminofluorene results in increased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression EXP 4-acetylaminofluorene results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
9,9-bis(4-hydroxyphenyl)fluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein]; 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28248286 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:28248286 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein] CTD PMID:28248286 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
fluoren-9-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 9-fluorenone results in increased expression of CYP1A1 protein CTD PMID:10445401 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP 9-fluorenone results in increased expression of CYP2B1 protein CTD PMID:10445401 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP 9-fluorenone results in increased expression of CYP3A2 protein CTD PMID:10445401 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
ledipasvir term browser