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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dimethyl sulfoxide
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Accession:CHEBI:28262 term browser browse the term
Definition:A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Synonyms:exact_synonym: (methanesulfinyl)methane
 related_synonym: (CH3)2SO;   Dimethylsulfoxid;   Formula=C2H6OS;   InChI=1S/C2H6OS/c1-4(2)3/h1-2H3;   InChIKey=IAZDPXIOMUYVGZ-UHFFFAOYSA-N;   S(O)Me2;   SMILES=CS(C)=O;   dimethyl sulfur oxide;   dimethyl sulphoxide;   dimethyli sulfoxidum;   dimethylsulfoxyde;   dimetil sulfoxido;   dmso;   methylsulfinylmethane;   sulfinylbis(methane)
 alt_id: CHEBI:23801;   CHEBI:42138;   CHEBI:4612
 xref: Beilstein:506008;   CAS:67-68-5;   Chemspider:659;   DrugBank:DB01093;   Drug_Central:906;   FooDB:FDB000764;   Gmelin:1556;   HMDB:HMDB0002151;   KEGG:C11143;   KEGG:D01043;   KNApSAcK:C00053120;   LINCS:LSM-36361
 xref_mesh: MESH:D004121
 xref: MetaCyc:DMSO;   PDBeChem:DMS;   PMID:10298633;   PMID:11162043;   PMID:11350866;   PMID:11474739;   PMID:12663039;   PMID:15237653;   PMID:15588915;   PMID:15868171;   PMID:16434015;   PMID:16522014;   PMID:19096138;   PMID:19382398;   PMID:19443933;   PMID:20828537;   PMID:21426213;   PMID:22030943;   PMID:22722716;   PMID:22768202;   PMID:22814967;   PMID:23050031;   PMID:23313473;   PMID:28220525;   PMID:29938311;   PMID:31489176;   PMID:3510103;   PMID:3898376;   PMID:3916302;   PMID:4223708;   PMID:4556944;   PMID:4963226;   PMID:6309056;   PMID:6379027;   Reaxys:506008;   UM-BBD_compID:c0236;   Wikipedia:Dimethyl_Sulfoxide



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dimethyl sulfoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin increases expression ISO Dimethyl Sulfoxide results in increased expression of A2M mRNA CTD PMID:12883083 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 affects expression EXP Dimethyl Sulfoxide affects the expression of ABCB1 mRNA CTD PMID:12843640 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA]
CTD PMID:11682029 PMID:35366062 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 increases expression
decreases expression
EXP Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA
Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA
CTD PMID:22105179 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589
JBrowse link
G AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 affects expression EXP Dimethyl Sulfoxide affects the expression of AGAP4 mRNA CTD PMID:24834073 NCBI chr10:45,825,594...45,854,690
Ensembl chr10:45,825,594...45,853,875
JBrowse link
G AGRP agouti related neuropeptide affects expression EXP Dimethyl Sulfoxide affects the expression of AGRP mRNA CTD PMID:24834073 NCBI chr16:67,482,571...67,483,547
Ensembl chr16:67,482,571...67,483,547
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions
increases expression
decreases expression
EXP
ISO
Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]
Dimethyl Sulfoxide results in increased expression of AHR protein
AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein]; Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]
Dimethyl Sulfoxide results in increased expression of AHR mRNA; Dimethyl Sulfoxide results in increased expression of AHR protein
Dimethyl Sulfoxide results in decreased expression of AHR mRNA
CTD PMID:16675542 PMID:22486318 PMID:33723743 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AICDA activation induced cytidine deaminase affects expression EXP Dimethyl Sulfoxide affects the expression of AICDA mRNA CTD PMID:24834073 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions
affects localization
ISO Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein]
Dimethyl Sulfoxide affects the localization of AIFM1 protein
CTD PMID:20423716 PMID:22535522 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 NCBI chr  X:55,009,055...55,030,977
Ensembl chr  X:55,009,055...55,030,977
JBrowse link
G ALB albumin decreases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in decreased expression of ALB mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of ALB mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased secretion of ALB protein
Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein
CTD PMID:14757319 PMID:22105179 PMID:35366062 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ANKRD13C-DT ANKRD13C divergent transcript affects expression EXP Dimethyl Sulfoxide affects the expression of ANKRD13C-DT mRNA CTD PMID:24834073 NCBI chr 1:70,354,811...70,368,023
Ensembl chr 1:70,354,786...70,385,339
JBrowse link
G APOA1 apolipoprotein A1 increases expression
increases activity
EXP
ISO
Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein
Dimethyl Sulfoxide results in increased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOM apolipoprotein M affects expression EXP Dimethyl Sulfoxide affects the expression of APOM mRNA CTD PMID:24834073 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) increases expression ISO Dimethyl Sulfoxide results in increased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G AR androgen receptor multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] CTD PMID:28377212 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARHGAP11B Rho GTPase activating protein 11B affects expression EXP Dimethyl Sulfoxide affects the expression of ARHGAP11B mRNA CTD PMID:24834073 NCBI chr15:30,626,128...30,649,229
Ensembl chr15:30,624,494...30,649,529
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions EXP
ISO
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]
CTD PMID:16675542 PMID:33723743 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 affects expression EXP Dimethyl Sulfoxide affects the expression of ARPC4 mRNA CTD PMID:24834073 NCBI chr 3:9,792,518...9,807,101
Ensembl chr 3:9,792,495...9,807,101
JBrowse link
G ASAH2B N-acylsphingosine amidohydrolase 2B affects expression EXP Dimethyl Sulfoxide affects the expression of ASAH2B mRNA CTD PMID:24834073 NCBI chr10:50,739,936...50,759,255
Ensembl chr10:50,739,318...50,816,495
JBrowse link
G ATF3 activating transcription factor 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATF3 mRNA CTD PMID:22193206 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA CTD PMID:22193206 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
JBrowse link
G ATP5MF ATP synthase membrane subunit f affects expression EXP Dimethyl Sulfoxide affects the expression of ATP5MF mRNA CTD PMID:24834073 NCBI chr 7:99,458,195...99,466,167
Ensembl chr 7:99,448,475...99,466,186
JBrowse link
G AURKAIP1 aurora kinase A interacting protein 1 affects expression EXP Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA CTD PMID:24834073 NCBI chr 1:1,373,736...1,375,207
Ensembl chr 1:1,373,730...1,375,207
JBrowse link
G BARHL2 BarH like homeobox 2 affects expression EXP Dimethyl Sulfoxide affects the expression of BARHL2 mRNA CTD PMID:24834073 NCBI chr 1:90,711,539...90,717,302
Ensembl chr 1:90,711,539...90,717,302
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in increased expression of BAX mRNA
Dimethyl Sulfoxide results in increased expression of BAX protein
Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA]
CTD PMID:17652743 PMID:36305173 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
ISO Dimethyl Sulfoxide results in decreased expression of BCL2 protein
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in decreased expression of BCL2 protein
CTD PMID:36305173 PMID:37365769 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BEND6 BEN domain containing 6 affects expression EXP Dimethyl Sulfoxide affects the expression of BEND6 mRNA CTD PMID:24834073 NCBI chr 6:56,955,107...57,027,346
Ensembl chr 6:56,955,107...57,027,346
JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of BTG2 mRNA CTD PMID:22193206 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G C16orf74 chromosome 16 open reading frame 74 affects expression EXP Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA CTD PMID:24834073 NCBI chr16:85,707,517...85,751,096
Ensembl chr16:85,690,084...85,751,129
JBrowse link
G C19orf81 chromosome 19 open reading frame 81 affects expression EXP Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA CTD PMID:24834073 NCBI chr19:50,649,445...50,659,306
Ensembl chr19:50,649,445...50,659,310
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943
JBrowse link
G CADM1 cell adhesion molecule 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
JBrowse link
G CASP3 caspase 3 multiple interactions
decreases expression
increases cleavage
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide co-treated with 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine] results in increased expression of CASP3 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of CASP3 protein; Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein
Dimethyl Sulfoxide results in decreased expression of CASP3 protein
Dimethyl Sulfoxide results in increased cleavage of CASP3 protein
CTD PMID:12370186 PMID:22535522 PMID:36305173 PMID:37365769 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] CTD PMID:9169468 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL16 C-C motif chemokine ligand 16 affects expression EXP Dimethyl Sulfoxide affects the expression of CCL16 mRNA CTD PMID:24834073 NCBI chr17:35,976,499...35,981,497
Ensembl chr17:35,976,493...35,981,497
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
decreases expression
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein]
Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA]
CTD PMID:10925121 PMID:14576080 PMID:15689417 PMID:17529908 PMID:21878375 More... NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL28 C-C motif chemokine ligand 28 affects expression EXP Dimethyl Sulfoxide affects the expression of CCL28 mRNA CTD PMID:24834073 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] CTD PMID:21878375 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD14 CD14 molecule increases expression EXP Dimethyl Sulfoxide results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD38 CD38 molecule multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] CTD PMID:15964820 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CD3G CD3 gamma subunit of T-cell receptor complex affects expression EXP Dimethyl Sulfoxide affects the expression of CD3G mRNA CTD PMID:24834073 NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161
JBrowse link
G CD59 CD59 molecule (CD59 blood group) multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] CTD PMID:12361925 PMID:15033018 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CDC25B cell division cycle 25B decreases expression ISO Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA CTD PMID:21296123 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G CDH1 cadherin 1 increases expression
multiple interactions
ISO
EXP
Dimethyl Sulfoxide results in increased expression of CDH1 mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CDH1 mRNA
CTD PMID:22193206 PMID:35366062 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH2 cadherin 2 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of CDH2 mRNA CTD PMID:35366062 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CEACAM19 CEA cell adhesion molecule 19 affects expression EXP Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA CTD PMID:24834073 NCBI chr19:44,665,860...44,684,355
Ensembl chr19:44,662,278...44,684,359
JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression ISO Dimethyl Sulfoxide results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CFAP300 cilia and flagella associated protein 300 affects expression EXP Dimethyl Sulfoxide affects the expression of CFAP300 mRNA CTD PMID:24834073 NCBI chr11:102,047,437...102,084,554
Ensembl chr11:102,047,437...102,084,554
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator affects expression EXP Dimethyl Sulfoxide affects the expression of CFLAR mRNA CTD PMID:24834073 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CGREF1 cell growth regulator with EF-hand domain 1 affects expression EXP Dimethyl Sulfoxide affects the expression of CGREF1 mRNA CTD PMID:24834073 NCBI chr 2:27,099,353...27,119,128
Ensembl chr 2:27,098,889...27,119,128
JBrowse link
G CHEK2 checkpoint kinase 2 affects expression EXP Dimethyl Sulfoxide affects the expression of CHEK2 mRNA CTD PMID:24834073 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CKLF chemokine like factor affects expression EXP Dimethyl Sulfoxide affects the expression of CKLF mRNA CTD PMID:24834073 NCBI chr16:66,552,563...66,566,287
Ensembl chr16:66,552,563...66,566,251
JBrowse link
G CLDN6 claudin 6 multiple interactions
decreases methylation
increases expression
EXP Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA]
Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter
Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA
CTD PMID:18661270 NCBI chr16:3,014,712...3,018,183
Ensembl chr16:3,014,712...3,020,071
JBrowse link
G CLDN8 claudin 8 increases expression EXP Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097
JBrowse link
G CLDN9 claudin 9 multiple interactions
increases expression
decreases methylation
EXP Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA]
Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA
Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter
CTD PMID:18661270 NCBI chr16:3,012,923...3,014,505
Ensembl chr16:3,012,923...3,014,505
JBrowse link
G CNTF ciliary neurotrophic factor affects expression EXP Dimethyl Sulfoxide affects the expression of CNTF mRNA CTD PMID:24834073 NCBI chr11:58,622,665...58,625,733
Ensembl chr11:58,622,665...58,625,733
JBrowse link
G COL11A1 collagen type XI alpha 1 chain increases expression ISO Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] CTD PMID:11682029 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA] CTD PMID:35366062 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G COL4A1 collagen type IV alpha 1 chain increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157
JBrowse link
G COL4A5 collagen type IV alpha 5 chain increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:108,439,838...108,697,545
Ensembl chr  X:108,439,838...108,697,545
JBrowse link
G COL5A1 collagen type V alpha 1 chain increases expression ISO Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 increases expression EXP Dimethyl Sulfoxide results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
JBrowse link
G CP ceruloplasmin increases expression ISO Dimethyl Sulfoxide results in increased expression of CP mRNA CTD PMID:22193206 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPM carboxypeptidase M increases expression ISO Dimethyl Sulfoxide results in increased expression of CPM mRNA CTD PMID:22193206 NCBI chr12:68,842,197...68,963,469
Ensembl chr12:68,842,197...68,971,570
JBrowse link
G CS citrate synthase multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
JBrowse link
G CSF1R colony stimulating factor 1 receptor increases expression EXP Dimethyl Sulfoxide results in increased expression of CSF1R mRNA CTD PMID:8445950 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 affects expression EXP Dimethyl Sulfoxide affects the expression of CSTPP1 mRNA CTD PMID:24834073 NCBI chr11:46,936,689...47,164,385
Ensembl chr11:46,936,689...47,164,385
JBrowse link
G CTH cystathionine gamma-lyase affects expression EXP Dimethyl Sulfoxide affects the expression of CTH mRNA CTD PMID:24834073 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CTNNB1 catenin beta 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of CTNNB1 protein CTD PMID:20091315 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CUTA cutA divalent cation tolerance homolog affects expression EXP Dimethyl Sulfoxide affects the expression of CUTA mRNA CTD PMID:24834073 NCBI chr 6:33,416,442...33,418,107
Ensembl chr 6:33,416,442...33,418,317
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 affects expression EXP Dimethyl Sulfoxide affects the expression of CXCL14 mRNA CTD PMID:24834073 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
decreases expression
increases expression
EXP [Dimethyl Sulfoxide co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]
Dimethyl Sulfoxide results in decreased expression of CXCL8 mRNA
Dimethyl Sulfoxide results in increased expression of CXCL8 mRNA
CTD PMID:8969274 PMID:10022265 PMID:17529908 PMID:18684396 PMID:24296301 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXXC4 CXXC finger protein 4 affects expression EXP Dimethyl Sulfoxide affects the expression of CXXC4 mRNA CTD PMID:24834073 NCBI chr 4:104,468,308...104,494,894
Ensembl chr 4:104,468,308...104,494,901
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] CTD PMID:10822027 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 affects expression
multiple interactions
increases expression
EXP
ISO
Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA
JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein]
Dimethyl Sulfoxide results in increased expression of CYP1A1; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:12147272 PMID:12843640 PMID:22486318 PMID:31096615 PMID:33723743 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 affects expression
increases expression
multiple interactions
EXP Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 protein; [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2
CTD PMID:12843640 PMID:18347083 PMID:30262279 PMID:35366062 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 affects expression
increases expression
EXP
ISO
Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1B1 protein
CTD PMID:12843640 PMID:33723743 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] CTD PMID:15964820 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 affects expression EXP Dimethyl Sulfoxide affects the expression of CYP2A6 mRNA CTD PMID:12843640 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions
increases expression
ISO
EXP
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 protein
Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2B6 protein
CTD PMID:20371638 PMID:30262279 PMID:31096615 PMID:35366062 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C19 protein
CTD PMID:19858067 PMID:35366062 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 protein CTD PMID:35366062 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] CTD PMID:11368792 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects expression
increases expression
increases activity
multiple interactions
EXP
ISO
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide results in increased activity of CYP2E1 protein
Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:1538706 PMID:3113478 PMID:3337723 PMID:8074729 PMID:9143349 More... NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 affects expression
multiple interactions
increases expression
EXP
ISO
Dimethyl Sulfoxide affects the expression of CYP3A4 mRNA
Dimethyl Sulfoxide inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]
Dimethyl Sulfoxide results in increased expression of CYP3A4 mRNA; Dimethyl Sulfoxide results in increased expression of CYP3A4 protein
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 protein; [Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA; [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP3A4; Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; trichostatin A affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]
CTD PMID:12843640 PMID:18347083 PMID:19858067 PMID:30262279 PMID:31096615 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 affects expression EXP Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA CTD PMID:12843640 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 affects expression EXP Dimethyl Sulfoxide affects the expression of CYP3A7 mRNA CTD PMID:12843640 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G CYSRT1 cysteine rich tail 1 affects expression EXP Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA CTD PMID:24834073 NCBI chr 9:137,225,174...137,226,315
Ensembl chr 9:137,225,174...137,226,315
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA CTD PMID:22193206 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DEPP1 DEPP autophagy regulator 1 affects expression EXP Dimethyl Sulfoxide affects the expression of DEPP1 mRNA CTD PMID:24834073 NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809
JBrowse link
G DFFA DNA fragmentation factor subunit alpha increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of DFFA protein CTD PMID:22535522 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529
JBrowse link
G DMAP1 DNA methyltransferase 1 associated protein 1 affects expression EXP Dimethyl Sulfoxide affects the expression of DMAP1 mRNA CTD PMID:24834073 NCBI chr 1:44,213,471...44,220,673
Ensembl chr 1:44,213,455...44,220,681
JBrowse link
G DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 9:34,989,745...34,998,900
Ensembl chr 9:34,989,641...34,998,900
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA CTD PMID:22193206 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G DNMT1 DNA methyltransferase 1 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G EAF2 ELL associated factor 2 affects expression EXP Dimethyl Sulfoxide affects the expression of EAF2 mRNA CTD PMID:24834073 NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526
JBrowse link
G EDN2 endothelin 2 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA CTD PMID:15619356 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683
JBrowse link
G EDNRA endothelin receptor type A multiple interactions ISO [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein CTD PMID:20561571 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EDNRB endothelin receptor type B multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]
Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein
CTD PMID:20561571 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link
G EEF1AKMT1 EEF1A lysine methyltransferase 1 affects expression EXP Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA CTD PMID:24834073 NCBI chr13:20,728,731...20,773,961
Ensembl chr13:20,728,731...20,773,961
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139
JBrowse link
G EGR1 early growth response 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EGR1 mRNA CTD PMID:22193206 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation
multiple interactions
ISO Dimethyl Sulfoxide results in increased phosphorylation of EIF4EBP1 protein
[Mechlorethamine co-treated with Dimethyl Sulfoxide] results in increased phosphorylation of EIF4EBP1 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of EIF4EBP1 protein]
CTD PMID:36708981 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940
JBrowse link
G EMP1 epithelial membrane protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr12:13,196,726...13,219,941
Ensembl chr12:13,196,723...13,219,941
JBrowse link
G ENDOG endonuclease G affects localization ISO Dimethyl Sulfoxide affects the localization of ENDOG protein CTD PMID:22535522 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of ENPP2 protein CTD PMID:22952646 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
JBrowse link
G EPPIN epididymal peptidase inhibitor affects expression EXP Dimethyl Sulfoxide affects the expression of EPPIN mRNA CTD PMID:24834073 NCBI chr20:45,540,626...45,547,401
Ensembl chr20:45,540,626...45,547,752
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G EVA1B eva-1 homolog B affects expression EXP Dimethyl Sulfoxide affects the expression of EVA1B mRNA CTD PMID:24834073 NCBI chr 1:36,322,030...36,324,154
Ensembl chr 1:36,322,030...36,324,154
JBrowse link
G FAS Fas cell surface death receptor increases expression EXP Dimethyl Sulfoxide results in increased expression of FAS protein CTD PMID:15998540 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FASLG mRNA CTD PMID:10925121 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FBXL21P F-box and leucine rich repeat protein 21, pseudogene affects expression EXP Dimethyl Sulfoxide affects the expression of FBXL21P mRNA CTD PMID:24834073 NCBI chr 5:135,930,297...135,941,996
Ensembl chr 5:135,934,368...135,941,671
JBrowse link
G FGG fibrinogen gamma chain increases expression ISO Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein CTD PMID:14757319 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G FLNC filamin C increases expression ISO Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274
JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Dimethyl Sulfoxide results in increased expression of FOS mRNA CTD PMID:22193206 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXA2 forkhead box A2 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA CTD PMID:22105179 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455
JBrowse link
G FRS3 fibroblast growth factor receptor substrate 3 affects expression EXP Dimethyl Sulfoxide affects the expression of FRS3 mRNA CTD PMID:24834073 NCBI chr 6:41,770,176...41,779,900
Ensembl chr 6:41,770,176...41,786,542
JBrowse link
G GAD1 glutamate decarboxylase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha affects expression EXP Dimethyl Sulfoxide affects the expression of GADD45A mRNA CTD PMID:24834073 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Dimethyl Sulfoxide affects the expression of GAPDH mRNA CTD PMID:12843640 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GATA4 GATA binding protein 4 decreases expression
increases expression
EXP Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA
Dimethyl Sulfoxide results in increased expression of GATA4 mRNA
CTD PMID:22105179 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATA6 GATA binding protein 6 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA CTD PMID:22105179 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G GJA1 gap junction protein alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJA1 mRNA CTD PMID:22193206 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJB1 gap junction protein beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB1 mRNA CTD PMID:8631141 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GJB2 gap junction protein beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB2 mRNA CTD PMID:8631141 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938
JBrowse link
G GLT8D1 glycosyltransferase 8 domain containing 1 affects expression EXP Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA CTD PMID:24834073 NCBI chr 3:52,694,486...52,705,791
Ensembl chr 3:52,694,486...52,706,032
JBrowse link
G GNG3 G protein subunit gamma 3 affects expression EXP Dimethyl Sulfoxide affects the expression of GNG3 mRNA CTD PMID:24834073 NCBI chr11:62,706,446...62,709,201
Ensembl chr11:62,707,676...62,709,201
JBrowse link
G GPBAR1 G protein-coupled bile acid receptor 1 decreases expression ISO DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 2:218,259,496...218,263,861
Ensembl chr 2:218,259,496...218,263,861
JBrowse link
G GPR75 G protein-coupled receptor 75 affects expression EXP Dimethyl Sulfoxide affects the expression of GPR75 mRNA CTD PMID:24834073 NCBI chr 2:53,852,912...53,859,967
Ensembl chr 2:53,852,912...53,859,967
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of GPT protein CTD PMID:37365769 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GRN granulin precursor increases expression EXP Dimethyl Sulfoxide results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTA1 protein] CTD PMID:12370186 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTA3 glutathione S-transferase alpha 3 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of GSTA3 mRNA CTD PMID:35750087 NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 affects expression EXP Dimethyl Sulfoxide affects the expression of GSTK1 mRNA CTD PMID:24834073 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] CTD PMID:12370186 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTM2 glutathione S-transferase mu 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GSTP1 mRNA CTD PMID:35750087 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G H1-3 H1.3 linker histone, cluster member affects expression EXP Dimethyl Sulfoxide affects the expression of H1-3 mRNA CTD PMID:24834073 NCBI chr 6:26,234,212...26,234,987
Ensembl chr 6:26,234,212...26,234,987
JBrowse link
G H2AC13 H2A clustered histone 13 affects expression EXP Dimethyl Sulfoxide affects the expression of H2AC13 mRNA CTD PMID:24834073 NCBI chr 6:27,808,173...27,808,667
Ensembl chr 6:27,808,173...27,808,667
JBrowse link
G H2AC17 H2A clustered histone 17 affects expression EXP Dimethyl Sulfoxide affects the expression of H2AC17 mRNA CTD PMID:24834073 NCBI chr 6:27,892,699...27,893,185
Ensembl chr 6:27,892,699...27,893,185
JBrowse link
G H2AC6 H2A clustered histone 6 affects expression EXP Dimethyl Sulfoxide affects the expression of H2AC6 mRNA CTD PMID:24834073 NCBI chr 6:26,124,172...26,124,690
Ensembl chr 6:26,124,145...26,139,116
JBrowse link
G H2BC17 H2B clustered histone 17 affects expression EXP Dimethyl Sulfoxide affects the expression of H2BC17 mRNA CTD PMID:24834073 NCBI chr 6:27,893,425...27,893,891
Ensembl chr 6:27,893,425...27,893,891
JBrowse link
G H2BC6 H2B clustered histone 6 affects expression EXP Dimethyl Sulfoxide affects the expression of H2BC6 mRNA CTD PMID:24834073 NCBI chr 6:26,183,761...26,184,230
Ensembl chr 6:26,172,059...26,184,655
JBrowse link
G H3-4 H3.4 histone, cluster member multiple interactions
decreases methylation
EXP [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein]
Dimethyl Sulfoxide results in decreased methylation of H3-4 protein
CTD PMID:15964820 NCBI chr 1:228,424,845...228,425,360
Ensembl chr 1:228,424,845...228,425,360
JBrowse link
G H3C6 H3 clustered histone 6 affects expression EXP Dimethyl Sulfoxide affects the expression of H3C6 mRNA CTD PMID:24834073 NCBI chr 6:26,224,178...26,227,473
Ensembl chr 6:26,224,199...26,227,473
JBrowse link
G H4C16 H4 histone 16 multiple interactions
increases methylation
EXP [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4C16 protein modified form binds to TGM2 gene]; [Dimethyl Sulfoxide co-treated with Alitretinoin] results in increased methylation of H4C16 protein; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4C16 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4C16 protein]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide results in increased methylation of H4C16 protein] CTD PMID:15964820 NCBI chr12:14,770,720...14,771,131
Ensembl chr12:14,767,999...14,771,131
JBrowse link
G HAND1 heart and neural crest derivatives expressed 1 decreases expression
increases expression
EXP Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA
Dimethyl Sulfoxide results in increased expression of HAND1 mRNA
CTD PMID:22105179 NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227
JBrowse link
G HBB hemoglobin subunit beta increases expression ISO Dimethyl Sulfoxide results in increased expression of HBB mRNA CTD PMID:21296123 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395
JBrowse link
G HCAR1 hydroxycarboxylic acid receptor 1 affects expression EXP Dimethyl Sulfoxide affects the expression of HCAR1 mRNA CTD PMID:24834073 NCBI chr12:122,726,076...122,730,844
Ensembl chr12:122,726,076...122,730,844
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein CTD PMID:16222702 NCBI chr17:45,148,475...45,152,099
Ensembl chr17:45,148,475...45,152,099
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression ISO Dimethyl Sulfoxide results in increased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha decreases expression EXP Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA CTD PMID:21878375 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
EXP
ISO
Dimethyl Sulfoxide results in decreased expression of HMOX1 protein
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA
CTD PMID:15689417 PMID:22118543 PMID:22193206 PMID:26497626 PMID:36305173 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin increases expression ISO Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein CTD PMID:14757319 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G HRAS HRas proto-oncogene, GTPase affects expression EXP Dimethyl Sulfoxide affects the expression of HRAS mRNA CTD PMID:24834073 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression ISO Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA CTD PMID:22193206 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] CTD PMID:18539414 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IER2 immediate early response 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,154,911
JBrowse link
G IFNG interferon gamma multiple interactions EXP [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] CTD PMID:21878375 PMID:29594315 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR1 interferon gamma receptor 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] CTD PMID:21878375 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449
JBrowse link
G IFT81 intraflagellar transport 81 affects expression EXP Dimethyl Sulfoxide affects the expression of IFT81 mRNA CTD PMID:24834073 NCBI chr12:110,124,357...110,218,793
Ensembl chr12:110,124,335...110,218,793
JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases expression
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of IL1B protein
Dimethyl Sulfoxide results in decreased expression of IL1B mRNA
CTD PMID:21878375 PMID:29594315 PMID:37365769 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R1 interleukin 1 receptor type 1 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL2 interleukin 2 multiple interactions EXP [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL23A interleukin 23 subunit alpha affects expression EXP Dimethyl Sulfoxide affects the expression of IL23A mRNA CTD PMID:24834073 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL6 interleukin 6 multiple interactions
decreases secretion
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased secretion of IL6 protein
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of IL6 protein; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]
CTD PMID:9378980 PMID:10022265 PMID:15689417 PMID:21878375 PMID:24296301 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRGM immunity related GTPase M affects expression EXP Dimethyl Sulfoxide affects the expression of IRGM mRNA CTD PMID:24834073 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736
JBrowse link
G ISG15 ISG15 ubiquitin like modifier affects expression EXP Dimethyl Sulfoxide affects the expression of ISG15 mRNA CTD PMID:24834073 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G ITGAM integrin subunit alpha M multiple interactions
increases expression
EXP [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of ITGAM protein] CTD PMID:7909661 PMID:15964820 PMID:16617325 PMID:22118543 PMID:26330309 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGAX integrin subunit alpha X multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] CTD PMID:15964820 NCBI chr16:31,355,176...31,382,999
Ensembl chr16:31,355,134...31,382,999
JBrowse link
G ITGB2 integrin subunit beta 2 multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] CTD PMID:15964820 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G JDP2 Jun dimerization protein 2 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein] CTD PMID:33723743 NCBI chr14:75,426,943...75,474,107
Ensembl chr14:75,427,716...75,474,111
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Dimethyl Sulfoxide results in increased expression of JUN mRNA
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA]
CTD PMID:7662713 PMID:22193206 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KLF2 KLF transcription factor 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF2 mRNA CTD PMID:22193206 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
JBrowse link
G KLF4 KLF transcription factor 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G KLHL41 kelch like family member 41 affects expression EXP Dimethyl Sulfoxide affects the expression of KLHL41 mRNA CTD PMID:24834073 NCBI chr 2:169,509,702...169,526,258
Ensembl chr 2:169,509,702...169,526,258
JBrowse link
G KRT15 keratin 15 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA CTD PMID:22105179 NCBI chr17:41,513,745...41,518,890
Ensembl chr17:41,513,745...41,522,529
JBrowse link
G KRT18 keratin 18 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of KRT18 mRNA CTD PMID:35366062 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
JBrowse link
G LAMA1 laminin subunit alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797
JBrowse link
G LAMB2 laminin subunit beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118
JBrowse link
G LDHC lactate dehydrogenase C affects expression EXP Dimethyl Sulfoxide affects the expression of LDHC mRNA CTD PMID:24834073 NCBI chr11:18,412,318...18,452,063
Ensembl chr11:18,412,318...18,452,063
JBrowse link
G LGALS1 galectin 1 affects expression EXP Dimethyl Sulfoxide affects the expression of LGALS1 mRNA CTD PMID:24834073 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 affects expression EXP Dimethyl Sulfoxide affects the expression of LLGL2 mRNA CTD PMID:24834073 NCBI chr17:75,525,002...75,575,209
Ensembl chr17:75,525,080...75,575,209
JBrowse link
G LRRC4 leucine rich repeat containing 4 affects expression EXP Dimethyl Sulfoxide affects the expression of LRRC4 mRNA CTD PMID:24834073 NCBI chr 7:128,027,071...128,032,128
Ensembl chr 7:128,027,071...128,032,107
JBrowse link
G LYRM9 LYR motif containing 9 affects expression EXP Dimethyl Sulfoxide affects the expression of LYRM9 mRNA CTD PMID:24834073 NCBI chr17:27,878,358...27,893,365
Ensembl chr17:27,878,314...27,894,752
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions
increases expression
EXP cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA] CTD PMID:31265865 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 increases expression
multiple interactions
EXP Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA]
CTD PMID:31265865 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
decreases activity
ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein]
Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein
CTD PMID:12370186 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 affects expression
multiple interactions
increases expression
EXP Dimethyl Sulfoxide affects the expression of MAPK3 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA]
CTD PMID:24834073 PMID:31265865 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAT1A methionine adenosyltransferase 1A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT1A protein CTD PMID:8373829 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658
JBrowse link
G MAT2A methionine adenosyltransferase 2A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT2A protein CTD PMID:8373829 NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281
JBrowse link
G MC1R melanocortin 1 receptor affects expression EXP Dimethyl Sulfoxide affects the expression of MC1R mRNA CTD PMID:24834073 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973
JBrowse link
G MEF2C myocyte enhancer factor 2C increases expression
decreases expression
EXP Dimethyl Sulfoxide results in increased expression of MEF2C mRNA
Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA
CTD PMID:22105179 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257
JBrowse link
G METTL26 methyltransferase like 26 affects expression EXP Dimethyl Sulfoxide affects the expression of METTL26 mRNA CTD PMID:24834073 NCBI chr16:634,430...636,305
Ensembl chr16:634,427...636,366
JBrowse link
G MFAP5 microfibril associated protein 5 affects expression EXP Dimethyl Sulfoxide affects the expression of MFAP5 mRNA CTD PMID:24834073 NCBI chr12:8,645,943...8,662,826
Ensembl chr12:8,637,346...8,662,888
JBrowse link
G MIR320A microRNA 320a multiple interactions ISO dimethyl sulfoxide promotes the reaction [ischemia-reperfusion injury increases expression of Mir320a miRNA in nucleus] RGD PMID:31089916 RGD:155882543 NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
JBrowse link
G MMP1 matrix metallopeptidase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP13 mRNA CTD PMID:35366062 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Dimethyl Sulfoxide results in increased expression of MMP2 protein
CTD PMID:26497626 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO
EXP
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP9 mRNA
Dimethyl Sulfoxide results in increased expression of MMP9 protein
CTD PMID:17603938 PMID:26497626 PMID:35366062 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase increases secretion ISO Dimethyl Sulfoxide results in increased secretion of MPO protein CTD PMID:21633126 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MRPL43 mitochondrial ribosomal protein L43 affects expression EXP Dimethyl Sulfoxide affects the expression of MRPL43 mRNA CTD PMID:24834073 NCBI chr10:100,977,820...100,987,497
Ensembl chr10:100,969,458...100,987,515
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] CTD PMID:10640773 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MXRA8 matrix remodeling associated 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 1:1,352,689...1,363,541
Ensembl chr 1:1,352,689...1,361,777
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP Dimethyl Sulfoxide results in decreased expression of MYC mRNA CTD PMID:7798212 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYL2 myosin light chain 2 multiple interactions
increases phosphorylation
ISO AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein] CTD PMID:33723743 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443
JBrowse link
G MYO1G myosin IG increases expression ISO Dimethyl Sulfoxide results in increased expression of MYO1G mRNA CTD PMID:22193206 NCBI chr 7:44,962,662...44,979,015
Ensembl chr 7:44,962,662...44,979,088
JBrowse link
G NANOG Nanog homeobox decreases expression EXP Dimethyl Sulfoxide results in decreased expression of NANOG mRNA CTD PMID:22105179 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G NEFH neurofilament heavy chain decreases expression EXP Dimethyl Sulfoxide results in decreased expression of NEFH mRNA CTD PMID:22105179 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
JBrowse link
G NES nestin decreases expression EXP Dimethyl Sulfoxide results in decreased expression of NES mRNA CTD PMID:22105179 NCBI chr 1:156,668,763...156,677,407
Ensembl chr 1:156,668,763...156,677,407
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
affects response to substance
decreases expression
ISO
EXP
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
Dimethyl Sulfoxide results in increased expression of NFE2L2 protein modified form
NFE2L2 protein affects the susceptibility to Dimethyl Sulfoxide
dimethyl sulfoxide promotes the reaction [ischemia-reperfusion injury increases expression of Nfe2l2 protein in nucleus]
Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]
Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein
CTD
RGD
PMID:26497626 PMID:32023790 PMID:33723743 PMID:36305173 PMID:31089916 RGD:155882543 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] CTD PMID:21878375 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] CTD PMID:21878375 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NMI N-myc and STAT interactor affects expression EXP Dimethyl Sulfoxide affects the expression of NMI mRNA CTD PMID:24834073 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G NMRK1 nicotinamide riboside kinase 1 affects expression EXP Dimethyl Sulfoxide affects the expression of NMRK1 mRNA CTD PMID:24834073 NCBI chr 9:75,060,577...75,088,155
Ensembl chr 9:75,060,573...75,088,217
JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA CTD PMID:21878375 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOTCH3 notch receptor 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of NQO1 mRNA CTD PMID:22193206 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression ISO DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions ISO NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G NUDT1 nudix hydrolase 1 affects expression EXP Dimethyl Sulfoxide affects the expression of NUDT1 mRNA CTD PMID:24834073 NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,226...2,251,146
JBrowse link
G OCLN occludin increases expression EXP Dimethyl Sulfoxide results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G ODC1 ornithine decarboxylase 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G ORM1 orosomucoid 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein CTD PMID:14757319 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
JBrowse link
G OSTN osteocrin affects expression EXP Dimethyl Sulfoxide affects the expression of OSTN mRNA CTD PMID:24834073 NCBI chr 3:191,199,241...191,265,615
Ensembl chr 3:191,199,241...191,265,615
JBrowse link
G P2RX7 purinergic receptor P2X 7 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of P2RX7 protein CTD PMID:37365769 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PADI4 peptidyl arginine deiminase 4 multiple interactions
increases expression
EXP Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] CTD PMID:15964820 PMID:29425503 NCBI chr 1:17,308,197...17,364,004
Ensembl chr 1:17,308,195...17,364,004
JBrowse link
G PARD6A par-6 family cell polarity regulator alpha affects expression EXP Dimethyl Sulfoxide affects the expression of PARD6A mRNA CTD PMID:24834073 NCBI chr16:67,660,960...67,662,774
Ensembl chr16:67,660,946...67,662,774
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PDCD4 programmed cell death 4 increases expression EXP Dimethyl Sulfoxide results in increased expression of PDCD4 protein CTD PMID:17259349 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G PGBD4 piggyBac transposable element derived 4 affects expression EXP Dimethyl Sulfoxide affects the expression of PGBD4 mRNA CTD PMID:24834073 NCBI chr15:34,102,083...34,108,686
Ensembl chr15:34,102,083...34,108,686
JBrowse link
G PHF6 PHD finger protein 6 affects expression EXP Dimethyl Sulfoxide affects the expression of PHF6 mRNA CTD PMID:24834073 NCBI chr  X:134,373,312...134,428,790
Ensembl chr  X:134,373,288...134,428,791
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing affects expression EXP Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA CTD PMID:24834073 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746
JBrowse link
G PJVK pejvakin affects expression EXP Dimethyl Sulfoxide affects the expression of PJVK mRNA CTD PMID:24834073 NCBI chr 2:178,451,378...178,462,102
Ensembl chr 2:178,451,346...178,462,102
JBrowse link
G PLA2G2A phospholipase A2 group IIA decreases expression EXP Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA CTD PMID:21878375 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G PLEKHF1 pleckstrin homology and FYVE domain containing 1 affects expression EXP Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA CTD PMID:24834073 NCBI chr19:29,665,461...29,675,477
Ensembl chr19:29,665,459...29,675,477
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725
JBrowse link
G POMC proopiomelanocortin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of POMC protein CTD PMID:15680486 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G POR cytochrome p450 oxidoreductase multiple interactions
decreases activity
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]
Dimethyl Sulfoxide results in decreased activity of POR protein
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein]
CTD PMID:11368792 PMID:21215309 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
JBrowse link
G POT1 protection of telomeres 1 multiple interactions EXP 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA CTD PMID:26330309 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G POU5F1 POU class 5 homeobox 1 affects expression EXP Dimethyl Sulfoxide affects the expression of POU5F1 mRNA CTD PMID:24834073 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression EXP Dimethyl Sulfoxide results in decreased expression of PPARA mRNA CTD PMID:21878375 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression EXP Dimethyl Sulfoxide results in decreased expression of PPARG mRNA CTD PMID:21878375 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PQBP1 polyglutamine binding protein 1 affects expression EXP Dimethyl Sulfoxide affects the expression of PQBP1 mRNA CTD PMID:24834073 NCBI chr  X:48,897,930...48,903,143
Ensembl chr  X:48,890,197...48,903,402
JBrowse link
G PRMT1 protein arginine methyltransferase 1 multiple interactions EXP PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] CTD PMID:31877331 NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029
JBrowse link
G PRPH peripherin affects expression EXP Dimethyl Sulfoxide affects the expression of PRPH mRNA CTD PMID:24834073 NCBI chr12:49,295,147...49,298,686
Ensembl chr12:49,295,147...49,298,686
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA CTD PMID:21878375 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Dimethyl Sulfoxide results in increased expression of PTGS2 protein
CTD PMID:21878375 PMID:26497626 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PXDN peroxidasin increases expression ISO Dimethyl Sulfoxide results in increased expression of PXDN mRNA CTD PMID:22193206 NCBI chr 2:1,631,887...1,744,901
Ensembl chr 2:1,631,887...1,744,852
JBrowse link
G PZP PZP alpha-2-macroglobulin like increases expression ISO Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein CTD PMID:14757319 NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,395
JBrowse link
G RAB3C RAB3C, member RAS oncogene family affects expression EXP Dimethyl Sulfoxide affects the expression of RAB3C mRNA CTD PMID:24834073 NCBI chr 5:58,582,152...58,859,394
Ensembl chr 5:58,582,221...58,859,394
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions EXP [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of RELA protein CTD PMID:37365769 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RELN reelin increases expression EXP Dimethyl Sulfoxide results in increased expression of RELN mRNA CTD PMID:17065238 NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658
JBrowse link
G RFX3 regulatory factor X3 affects expression EXP Dimethyl Sulfoxide affects the expression of RFX3 mRNA CTD PMID:24834073 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004
JBrowse link
G RLN2 relaxin 2 affects expression EXP Dimethyl Sulfoxide affects the expression of RLN2 mRNA CTD PMID:24834073 NCBI chr 9:5,299,864...5,339,326
Ensembl chr 9:5,299,864...5,304,716
JBrowse link
G RNASE4 ribonuclease A family member 4 affects expression EXP Dimethyl Sulfoxide affects the expression of RNASE4 mRNA CTD PMID:24834073 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216
JBrowse link
G RNF152 ring finger protein 152 affects expression EXP Dimethyl Sulfoxide affects the expression of RNF152 mRNA CTD PMID:24834073 NCBI chr18:61,808,067...61,894,412
Ensembl chr18:61,808,067...61,894,247
JBrowse link
G RPP38-DT RPP38 divergent transcript affects expression EXP Dimethyl Sulfoxide affects the expression of RPP38-DT mRNA CTD PMID:24834073 NCBI chr10:15,095,385...15,097,319
Ensembl chr10:15,095,385...15,097,319
JBrowse link
G RPS6 ribosomal protein S6 increases phosphorylation
multiple interactions
affects phosphorylation
ISO
EXP
Dimethyl Sulfoxide results in increased phosphorylation of RPS6 protein
[Dimethyl Sulfoxide co-treated with Mechlorethamine] results in increased phosphorylation of RPS6 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of RPS6 protein]
Mechlorethamine affects the reaction [Dimethyl Sulfoxide affects the phosphorylation of RPS6 protein]
CTD PMID:36708981 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
JBrowse link
G RXRA retinoid X receptor alpha increases expression
affects response to substance
ISO Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein
RXRA protein affects the susceptibility to Dimethyl Sulfoxide
CTD PMID:9751115 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G RXRG retinoid X receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of RXRG protein CTD PMID:9751115 NCBI chr 1:165,400,922...165,445,126
Ensembl chr 1:165,400,922...165,445,355
JBrowse link
G S100A13 S100 calcium binding protein A13 affects expression EXP Dimethyl Sulfoxide affects the expression of S100A13 mRNA CTD PMID:24834073 NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360
JBrowse link
G S100A8 S100 calcium binding protein A8 increases expression EXP Dimethyl Sulfoxide results in increased expression of S100A8 mRNA CTD PMID:1733233 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression EXP Dimethyl Sulfoxide results in increased expression of S100A9 mRNA CTD PMID:1733233 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
JBrowse link
G SDHAF4 succinate dehydrogenase complex assembly factor 4 affects expression EXP Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA CTD PMID:24834073 NCBI chr 6:70,566,930...70,598,428
Ensembl chr 6:70,566,917...70,589,569
JBrowse link
G SELENBP1 selenium binding protein 1 increases abundance EXP SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide CTD PMID:29255262 NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707
JBrowse link
G SERP2 stress associated endoplasmic reticulum protein family member 2 affects expression EXP Dimethyl Sulfoxide affects the expression of SERP2 mRNA CTD PMID:24834073 NCBI chr13:44,373,647...44,397,714
Ensembl chr13:44,373,665...44,397,714
JBrowse link
G SFTA3 surfactant associated 3 affects expression EXP Dimethyl Sulfoxide affects the expression of SFTA3 mRNA CTD PMID:24834073 NCBI chr14:36,473,288...36,519,556
Ensembl chr14:36,473,288...36,513,829
Ensembl chr14:36,473,288...36,513,829
JBrowse link
G SLC24A2 solute carrier family 24 member 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 9:19,507,455...20,307,892
Ensembl chr 9:19,507,452...19,789,037
JBrowse link
G SLC24A4 solute carrier family 24 member 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr14:92,322,581...92,501,481
Ensembl chr14:92,322,581...92,501,481
JBrowse link
G SLC2A6 solute carrier family 2 member 6 affects expression EXP Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA CTD PMID:24834073 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127
JBrowse link
G SLC35E4 solute carrier family 35 member E4 affects expression EXP Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA CTD PMID:24834073 NCBI chr22:30,635,781...30,669,019
Ensembl chr22:30,635,781...30,669,016
JBrowse link
G SMAD2 SMAD family member 2 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD2 protein modified form CTD PMID:35366062 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD3 protein modified form CTD PMID:35366062 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMAD4 SMAD family member 4 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD4 protein CTD PMID:35366062 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
JBrowse link
G SNAI1 snail family transcriptional repressor 1 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI1 mRNA CTD PMID:35366062 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI2 mRNA CTD PMID:35366062 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SNX15 sorting nexin 15 affects expression EXP Dimethyl Sulfoxide affects the expression of SNX15 mRNA CTD PMID:24834073 NCBI chr11:65,027,439...65,040,572
Ensembl chr11:65,027,439...65,040,572
JBrowse link
G SOD3 superoxide dismutase 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SORD sorbitol dehydrogenase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] CTD PMID:17177172 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185
JBrowse link
G SOX17 SRY-box transcription factor 17 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892
JBrowse link
G SP1 Sp1 transcription factor multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G SPINK2 serine peptidase inhibitor Kazal type 2 affects expression EXP Dimethyl Sulfoxide affects the expression of SPINK2 mRNA CTD PMID:24834073 NCBI chr 4:56,809,860...56,821,869
Ensembl chr 4:56,809,860...56,821,742
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression ISO DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SRXN1 sulfiredoxin 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G STAC3 SH3 and cysteine rich domain 3 affects expression EXP Dimethyl Sulfoxide affects the expression of STAC3 mRNA CTD PMID:24834073 NCBI chr12:57,243,458...57,251,187
Ensembl chr12:57,243,453...57,251,188
JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:14570759 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
JBrowse link
G SUMO1 small ubiquitin like modifier 1 affects expression EXP Dimethyl Sulfoxide affects the expression of SUMO1 mRNA CTD PMID:24834073 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599
JBrowse link
G SYCE2 synaptonemal complex central element protein 2 affects expression EXP Dimethyl Sulfoxide affects the expression of SYCE2 mRNA CTD PMID:24834073 NCBI chr19:12,898,786...12,919,293
Ensembl chr19:12,898,786...12,919,293
JBrowse link
G TAS2R14 taste 2 receptor member 14 affects expression EXP Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA CTD PMID:24834073 NCBI chr12:10,937,410...10,939,263
Ensembl chr12:10,937,408...11,171,573
JBrowse link
G TATDN1 TatD DNase domain containing 1 affects expression EXP Dimethyl Sulfoxide affects the expression of TATDN1 mRNA CTD PMID:24834073 NCBI chr 8:124,488,494...124,539,088
Ensembl chr 8:124,488,485...124,539,458
JBrowse link
G TERC telomerase RNA component multiple interactions EXP 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA CTD PMID:26330309 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047
JBrowse link
G TERF1 telomeric repeat binding factor 1 multiple interactions EXP 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123
JBrowse link
G TERF2 telomeric repeat binding factor 2 multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA CTD PMID:26330309 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TERT telomerase reverse transcriptase decreases expression
multiple interactions
ISO
EXP
Dimethyl Sulfoxide results in decreased expression of TERT mRNA
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA
CTD PMID:16180984 PMID:26330309 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TF transferrin increases expression ISO Dimethyl Sulfoxide results in increased expression of TF mRNA CTD PMID:22193206 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TFPI tissue factor pathway inhibitor affects expression EXP Dimethyl Sulfoxide affects the expression of TFPI mRNA CTD PMID:24834073 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased abundance of Adenosine Triphosphate; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of ALB mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CDH1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C19 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of KRT18 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP13 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased secretion of ALB protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of CDH2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD2 protein modified form; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD3 protein modified form; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD4 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of VIM mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB2 mRNA; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA]; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA] CTD PMID:35366062 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGM2 transglutaminase 2 multiple interactions EXP [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4C16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] CTD PMID:15964820 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP1 mRNA CTD PMID:35366062 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP2 mRNA
CTD PMID:11682029 PMID:35366062 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TIRAP TIR domain containing adaptor protein affects expression EXP Dimethyl Sulfoxide affects the expression of TIRAP mRNA CTD PMID:24834073 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845
JBrowse link
G TJP1 tight junction protein 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TMEM121 transmembrane protein 121 affects expression EXP Dimethyl Sulfoxide affects the expression of TMEM121 mRNA CTD PMID:24834073 NCBI chr14:105,526,583...105,530,198
Ensembl chr14:105,526,583...105,530,198
JBrowse link
G TMEM134 transmembrane protein 134 affects expression EXP Dimethyl Sulfoxide affects the expression of TMEM134 mRNA CTD PMID:24834073 NCBI chr11:67,461,710...67,469,251
Ensembl chr11:67,461,710...67,469,272
JBrowse link
G TMEM150C transmembrane protein 150C affects expression EXP Dimethyl Sulfoxide affects the expression of TMEM150C mRNA CTD PMID:24834073 NCBI chr 4:82,483,176...82,562,253
Ensembl chr 4:82,483,170...82,562,357
JBrowse link
G TMEM266 transmembrane protein 266 affects expression EXP Dimethyl Sulfoxide affects the expression of TMEM266 mRNA CTD PMID:24834073 NCBI chr15:76,059,985...76,204,963
Ensembl chr15:76,059,958...76,229,121
JBrowse link
G TMIGD2 transmembrane and immunoglobulin domain containing 2 affects expression EXP Dimethyl Sulfoxide affects the expression of TMIGD2 mRNA CTD PMID:24834073 NCBI chr19:4,292,227...4,302,389
Ensembl chr19:4,292,227...4,302,431
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of TNF protein; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]
CTD PMID:7539275 PMID:14576080 PMID:21878375 PMID:22319556 PMID:37365769 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A increases expression ISO Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] CTD PMID:9870925 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TOMM5 translocase of outer mitochondrial membrane 5 affects expression EXP Dimethyl Sulfoxide affects the expression of TOMM5 mRNA CTD PMID:24834073 NCBI chr 9:37,588,413...37,592,597
Ensembl chr 9:37,582,646...37,592,604
JBrowse link
G TPM3 tropomyosin 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 1:154,155,308...154,192,100
Ensembl chr 1:154,155,308...154,194,648
JBrowse link
G TRA2B transformer 2 beta homolog increases expression ISO Dimethyl Sulfoxide results in increased expression of TRA2B mRNA CTD PMID:22193206 NCBI chr 3:185,914,558...185,938,014
Ensembl chr 3:185,914,558...185,938,103
JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TSC22D3 TSC22 domain family member 3 affects expression EXP Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA CTD PMID:24834073 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G TSNARE1 t-SNARE domain containing 1 affects expression EXP Dimethyl Sulfoxide affects the expression of TSNARE1 mRNA CTD PMID:24834073 NCBI chr 8:142,212,080...142,407,029
Ensembl chr 8:142,212,080...142,403,182
JBrowse link
G TUBB3 tubulin beta 3 class III decreases expression EXP Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA CTD PMID:22105179 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761
JBrowse link
G U2AF1L4 U2 small nuclear RNA auxiliary factor 1 like 4 affects expression EXP Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA CTD PMID:24834073 NCBI chr19:35,742,464...35,745,418
Ensembl chr19:35,742,464...35,745,445
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C affects expression EXP Dimethyl Sulfoxide affects the expression of UBE2C mRNA CTD PMID:24834073 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
JBrowse link
G UFSP1 UFM1 specific peptidase 1 (inactive) affects expression EXP Dimethyl Sulfoxide affects the expression of UFSP1 mRNA CTD PMID:24834073 NCBI chr 7:100,888,721...100,889,715
Ensembl chr 7:100,888,721...100,889,715
JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 affects expression EXP Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 affects expression EXP Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA CTD PMID:12843640 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
JBrowse link
G UPK3B uroplakin 3B affects expression EXP Dimethyl Sulfoxide affects the expression of UPK3B mRNA CTD PMID:24834073 NCBI chr 7:76,510,552...76,516,522
Ensembl chr 7:76,510,525...76,516,522
JBrowse link
G UTS2R urotensin 2 receptor affects expression EXP Dimethyl Sulfoxide affects the expression of UTS2R mRNA CTD PMID:24834073 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,765...82,377,458
JBrowse link
G VIM vimentin multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of VIM mRNA CTD PMID:35366062 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G VN1R2 vomeronasal 1 receptor 2 affects expression EXP Dimethyl Sulfoxide affects the expression of VN1R2 mRNA CTD PMID:24834073 NCBI chr19:53,258,292...53,259,602
Ensembl chr19:53,258,292...53,261,837
JBrowse link
G WAPL WAPL cohesin release factor increases expression EXP Dimethyl Sulfoxide results in increased expression of WAPL mRNA CTD PMID:15797623 NCBI chr10:86,435,256...86,521,792
Ensembl chr10:86,435,256...86,521,792
JBrowse link
G WNT11 Wnt family member 11 affects expression EXP Dimethyl Sulfoxide affects the expression of WNT11 mRNA CTD PMID:24834073 NCBI chr11:76,186,325...76,210,761
Ensembl chr11:76,186,325...76,210,736
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB1 mRNA CTD PMID:35366062 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 multiple interactions EXP [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB2 mRNA CTD PMID:35366062 NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057
JBrowse link
G ZFP36 ZFP36 ring finger protein affects expression EXP Dimethyl Sulfoxide affects the expression of ZFP36 mRNA CTD PMID:24834073 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,412
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      chemical role 24242
        antioxidant 17487
          radical scavenger 7211
            dimethyl sulfoxide 347
              trametinib dimethyl sulfoxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            heteroorganic entity 24766
                              organochalcogen compound 24378
                                organosulfur compound 19531
                                  sulfoxide 7190
                                    dimethyl sulfoxide 347
                                      trametinib dimethyl sulfoxide 0
paths to the root