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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N(omega)-methyl-L-arginine
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Accession:CHEBI:28229 term browser browse the term
Definition:A L-arginine derivative with a N(omega)-methyl substituent.
Synonyms:exact_synonym: (2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid;   (2S)-2-amino-5-{[imino(methylamino)methyl]amino}pentanoic acid;   N(5)-(N-methylcarbamimidoyl)-L-ornithine;   N(5)-[imino(methylamino)methyl]-L-ornithine
 related_synonym: Formula=C7H16N4O2;   InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1;   InChIKey=NTNWOCRCBQPEKQ-YFKPBYRVSA-N;   L-NMMA;   L-monomethylarginine;   N(5)-(methylamidino)-L-ornithine;   N(5)-(metilamidino)-L-ornitina;   N(G)-monomethyl-L-arginine;   N-monomethyl-L-arginine;   Ngamma-Monomethyl-L-arginine;   SMILES=C(NC(=N)NC)CC[C@@H](C(=O)O)N;   acide (2S)-2-amino-5-(3-methylguanidino)pentanoique;   omega-N-methylarginine;   omega-N-monomethylarginine;   targinina;   targinine;   targininum;   tilarginina;   tilarginine;   tilargininum
 alt_id: CHEBI:21921;   CHEBI:25685;   CHEBI:7547
 xref: Beilstein:2262067;   CAS:17035-90-4;   KEGG:C03884
 xref_mesh: MESH:D019323
 xref: PDBeChem:NMM
 cyclic_relationship: is_conjugate_acid_of CHEBI:67015;   is_tautomer_of CHEBI:60257


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N(omega)-methyl-L-arginine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein] CTD PMID:32526215 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein] CTD PMID:32526215 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      application 19413
        indicator 8669
          biomarker 6441
            L-arginine 51
              L-arginine derivative 44
                N(omega)-methyl-L-arginine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic group 18603
                              organic divalent group 18594
                                organodiyl group 18594
                                  carbonyl group 18507
                                    carbonyl compound 18507
                                      carboxylic acid 18159
                                        amino acid 14111
                                          alpha-amino acid 11596
                                            L-alpha-amino acid 11431
                                              glutamine family amino acid 10255
                                                L-arginine 51
                                                  L-arginine derivative 44
                                                    N(omega)-methyl-L-arginine 4
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