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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N(omega)-methyl-L-arginine
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Accession:CHEBI:28229 term browser browse the term
Definition:A L-arginine derivative with a N(omega)-methyl substituent.
Synonyms:exact_synonym: (2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid;   (2S)-2-amino-5-{[imino(methylamino)methyl]amino}pentanoic acid;   N(5)-(N-methylcarbamimidoyl)-L-ornithine;   N(5)-[imino(methylamino)methyl]-L-ornithine
 related_synonym: Formula=C7H16N4O2;   InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1;   InChIKey=NTNWOCRCBQPEKQ-YFKPBYRVSA-N;   L-NMMA;   L-monomethylarginine;   N(5)-(methylamidino)-L-ornithine;   N(5)-(metilamidino)-L-ornitina;   N(G)-monomethyl-L-arginine;   N-monomethyl-L-arginine;   Ngamma-Monomethyl-L-arginine;   SMILES=C(NC(=N)NC)CC[C@@H](C(=O)O)N;   acide (2S)-2-amino-5-(3-methylguanidino)pentanoique;   omega-N-methylarginine;   omega-N-monomethylarginine;   targinina;   targinine;   targininum;   tilarginina;   tilarginine;   tilargininum
 alt_id: CHEBI:21921;   CHEBI:25685;   CHEBI:7547
 xref: Beilstein:2262067;   CAS:17035-90-4;   KEGG:C03884
 xref_mesh: MESH:D019323
 xref: PDBeChem:NMM
 cyclic_relationship: is_conjugate_acid_of CHEBI:67015;   is_tautomer_of CHEBI:60257


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N(omega)-methyl-L-arginine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein] CTD PMID:32526215 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO omega-N-Methylarginine inhibits the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; omega-N-Methylarginine inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein] CTD PMID:32526215 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20849
    role 20820
      application 20622
        indicator 8821
          biomarker 6603
            L-arginine 125
              L-arginine derivative 101
                N(omega)-methyl-L-arginine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 20849
    subatomic particle 20847
      composite particle 20860
        hadron 20847
          baryon 20860
            nucleon 20847
              atomic nucleus 20847
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20565
                        hydrogen molecular entity 20549
                          hydrides 19684
                            inorganic hydride 18588
                              pnictogen hydride 18592
                                nitrogen hydride 18506
                                  azane 18249
                                    ammonia 18263
                                      organic amino compound 18263
                                        amino acid 16341
                                          alpha-amino acid 14253
                                            L-alpha-amino acid 12391
                                              glutamine family amino acid 10344
                                                L-arginine 125
                                                  L-arginine derivative 101
                                                    N(omega)-methyl-L-arginine 4
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