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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA] |
CTD |
PMID:29935282 |
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NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions |
ISO |
benzamide inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein] |
CTD |
PMID:15589979 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Casp3 |
caspase 3 |
increases activity |
ISO |
benzamide results in increased activity of CASP3 protein |
CTD |
PMID:18695944 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
increases expression |
ISO |
benzamide results in increased expression of CHRM1 mRNA; benzamide results in increased expression of CHRM1 protein |
CTD |
PMID:18501976 |
|
NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
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G |
Csf1 |
colony stimulating factor 1 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of DCSTAMP mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK1 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK3 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFKBIA protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of RELA protein modified form] |
CTD |
PMID:29935282 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Ctsd |
cathepsin D |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to CTSD promoter]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to CTSD promoter]] |
CTD |
PMID:17157789 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsk |
cathepsin K |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:29935282 |
|
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions |
ISO EXP |
benzamide analog binds to and results in decreased activity of CXCR1 protein |
CTD |
PMID:17181143 |
|
NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
EXP |
benzamide analog binds to and results in decreased activity of CXCR2 protein |
CTD |
PMID:17181143 |
|
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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G |
Dcstamp |
dendrocyte expressed seven transmembrane protein |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of DCSTAMP mRNA] |
CTD |
PMID:29935282 |
|
NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
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G |
Egfr |
epidermal growth factor receptor |
decreases activity |
ISO |
benzamide analog results in decreased activity of EGFR protein |
CTD |
PMID:15186837 |
|
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to CTSD promoter]]; benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to MYC promoter]]; benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to NCOA3 protein]]; benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to TFF1 promoter]]; benzamide analog inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased localization of ESR1 protein]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to CTSD promoter]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to MYC promoter]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to NCOA3 protein]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to TFF1 promoter]]; benzamide analog inhibits the reaction [Tamoxifen results in increased phosphorylation of and results in increased localization of ESR1 protein] |
CTD |
PMID:17157789 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
multiple interactions |
ISO |
benzamide analog binds to and results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]] |
CTD |
PMID:18762200 |
|
NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gabrb2 |
gamma-aminobutyric acid type A receptor subunit beta 2 |
multiple interactions |
ISO |
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]] |
CTD |
PMID:18762200 |
|
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
multiple interactions |
ISO |
benzamide analog binds to and results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] |
CTD |
PMID:18762200 |
|
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
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G |
Gabrd |
gamma-aminobutyric acid type A receptor subunit delta |
multiple interactions |
ISO |
benzamide analog binds to and results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]] |
CTD |
PMID:18762200 |
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NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
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G |
Gck |
glucokinase |
increases activity |
ISO |
benzamide analog results in increased activity of GCK protein |
CTD |
PMID:19758809 |
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NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
multiple interactions |
ISO |
[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein; benzamide promotes the reaction [[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of GPD1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] |
CTD |
PMID:2523799 |
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NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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G |
Hdac1 |
histone deacetylase 1 |
decreases activity |
ISO |
benzamide analog results in decreased activity of HDAC1 protein |
CTD |
PMID:19362838 |
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NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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G |
Hdac3 |
histone deacetylase 3 |
decreases activity |
ISO |
benzamide analog results in decreased activity of HDAC3 protein |
CTD |
PMID:19362838 |
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NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
decreases activity |
ISO |
benzamide analog results in decreased activity of HSD11B1 protein |
CTD |
PMID:18553955 PMID:19217779 PMID:19564108 |
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NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Ifng |
interferon gamma |
multiple interactions decreases expression |
EXP |
benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA] benzamide results in decreased expression of IFNG mRNA |
CTD |
PMID:12411406 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il1b |
interleukin 1 beta |
decreases expression |
EXP |
benzamide results in decreased expression of IL1B mRNA |
CTD |
PMID:12411406 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
EXP |
benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA] benzamide results in decreased expression of IL2 mRNA |
CTD |
PMID:12411406 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
decreases activity |
ISO |
benzamide analog results in decreased activity of LYN protein |
CTD |
PMID:17376680 |
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NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK1 protein modified form] |
CTD |
PMID:29935282 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK3 protein modified form] |
CTD |
PMID:29935282 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA] |
CTD |
PMID:29935282 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpl |
MPL proto-oncogene, thrombopoietin receptor |
multiple interactions |
ISO |
benzamide analog binds to and results in increased activity of MPL protein |
CTD |
PMID:18396041 |
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NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to MYC promoter]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to MYC promoter]] |
CTD |
PMID:17157789 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Ncoa3 |
nuclear receptor coactivator 3 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to NCOA3 protein]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to NCOA3 protein]] |
CTD |
PMID:17157789 |
|
NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA] |
CTD |
PMID:29935282 |
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NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFKBIA protein modified form] |
CTD |
PMID:29935282 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
decreases expression |
ISO EXP |
benzamide results in decreased expression of NOS2 mRNA; benzamide results in decreased expression of NOS2 protein |
CTD |
PMID:12411406 PMID:18501976 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Oprm1 |
opioid receptor, mu 1 |
multiple interactions |
ISO |
benzamide inhibits the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]; benzamide inhibits the reaction [PARP1 protein binds to MOR enhancer mutant form]; benzamide inhibits the reaction [TNF protein promotes the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]] |
CTD |
PMID:19447888 |
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NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
multiple interactions |
ISO |
benzamide inhibits the reaction [PARG affects the susceptibility to Methylnitronitrosoguanidine]; benzamide inhibits the reaction [PARG affects the susceptibility to Vitamin K 3] |
CTD |
PMID:15591342 |
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NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions decreases activity decreases expression |
ISO EXP |
[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]; [benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]; benzamide inhibits the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]; benzamide inhibits the reaction [PARP1 protein binds to MOR enhancer mutant form]; benzamide inhibits the reaction [TNF protein promotes the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]] [benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Hydrogen Peroxide; [benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; benzamide inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; benzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD] benzamide results in decreased expression of PARP1 protein |
CTD |
PMID:11593040 PMID:12411406 PMID:17669606 PMID:18695944 PMID:19447888 PMID:19998477 More...
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression |
EXP |
benzamide results in increased expression of PCNA protein |
CTD |
PMID:11049868 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
EXP |
benzamide results in decreased expression of PTGS2 mRNA |
CTD |
PMID:12411406 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Pygl |
glycogen phosphorylase L |
decreases activity |
ISO |
benzamide analog results in decreased activity of PYGL protein |
CTD |
PMID:19758809 |
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NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of RELA protein modified form] |
CTD |
PMID:29935282 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sirt1 |
sirtuin 1 |
decreases activity |
ISO |
benzamide analog results in decreased activity of SIRT1 protein |
CTD |
PMID:19616958 |
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NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Slc6a9 |
solute carrier family 6 member 9 |
multiple interactions |
EXP |
benzamide analog binds to and results in decreased activity of SLC6A9 protein |
CTD |
PMID:18355687 |
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NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
decreases activity |
ISO |
benzamide analog results in decreased activity of SRC protein |
CTD |
PMID:15186837 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Tep1 |
telomerase associated protein 1 |
decreases expression |
ISO |
benzamide results in decreased expression of TEP1 mRNA; benzamide results in decreased expression of TEP1 protein |
CTD |
PMID:16098204 |
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NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526
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G |
Tert |
telomerase reverse transcriptase |
decreases activity decreases ADP-ribosylation |
ISO |
benzamide results in decreased activity of TERT protein benzamide results in decreased ADP-ribosylation of TERT protein |
CTD |
PMID:16098204 |
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NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
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G |
Tff1 |
trefoil factor 1 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [Estradiol promotes the reaction [ESR1 protein binds to TFF1 promoter]]; benzamide analog inhibits the reaction [Tamoxifen promotes the reaction [ESR1 protein binds to TFF1 promoter]] |
CTD |
PMID:17157789 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions |
EXP ISO |
benzamide results in decreased expression of TNF mRNA benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA] benzamide inhibits the reaction [TNF protein promotes the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]] |
CTD |
PMID:12411406 PMID:19447888 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions |
ISO |
benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of DCSTAMP mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK1 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MAPK3 protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFKBIA protein modified form]; benzamide analog inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of RELA protein modified form] |
CTD |
PMID:29935282 |
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NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
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G |
Cyb5b |
cytochrome b5 type B |
multiple interactions |
ISO |
[CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime |
CTD |
PMID:22924387 |
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NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
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G |
Cyb5r3 |
cytochrome b5 reductase 3 |
multiple interactions |
ISO |
[CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime |
CTD |
PMID:22924387 |
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NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
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G |
Mtarc1 |
mitochondrial amidoxime reducing component 1 |
multiple interactions |
ISO |
[CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime |
CTD |
PMID:22924387 |
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NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
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G |
Mtarc2 |
mitochondrial amidoxime reducing component 2 |
multiple interactions |
ISO |
[CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime |
CTD |
PMID:22924387 |
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NCBI chr13:96,362,810...96,397,284
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
multiple interactions |
ISO |
UGT1A1 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime |
CTD |
PMID:15788365 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
multiple interactions |
ISO |
UGT1A3 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime |
CTD |
PMID:15788365 |
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NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
decreases phosphorylation |
ISO |
imatinib inhibits the reaction [collagen increases autophosphorylation of DDR1 in U2OS cells] |
RGD |
PMID:24768818 |
RGD:151347549 |
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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G |
Adra2a |
adrenoceptor alpha 2A |
increases expression |
ISO |
Indapamide results in increased expression of ADRA2A protein |
CTD |
PMID:2829625 |
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NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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G |
Arhgap45 |
Rho GTPase activating protein 45 |
affects expression |
ISO |
Indapamide affects the expression of ARHGAP45 mRNA |
CTD |
PMID:25811541 |
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NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
affects expression |
EXP |
Indapamide affects the expression of FOS mRNA |
CTD |
PMID:11779033 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Mapk1 |
mitogen activated protein kinase 1 |
affects phosphorylation |
EXP |
Indapamide affects the phosphorylation of MAPK1 protein |
CTD |
PMID:11779033 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
affects phosphorylation |
EXP |
Indapamide affects the phosphorylation of MAPK3 protein |
CTD |
PMID:11779033 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Ren |
renin |
increases expression |
ISO |
Indapamide results in increased expression of REN protein |
CTD |
PMID:6578003 |
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NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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G |
RT1-DOa |
RT1 class II, locus DOa |
affects expression |
ISO |
Indapamide affects the expression of HLA-DOA mRNA |
CTD |
PMID:25811541 |
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NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Indapamide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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