Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:theophylline
go back to main search page
Accession:CHEBI:28177 term browser browse the term
Definition:A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.
Synonyms:exact_synonym: 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
 related_synonym: 1,3-Dimethylxanthine;   1,3-dimethyl-7H-purine-2,6-dione;   Elixophyllin;   Formula=C7H8N4O2;   InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9);   InChIKey=ZFXYFBGIUFBOJW-UHFFFAOYSA-N;   Respbid;   SMILES=Cn1c2nc[nH]c2c(=O)n(C)c1=O;   Theo-Dur;   Theolair;   Theophyllin;   Uniphyl;   theophylline anhydrous
 alt_id: CHEBI:26940;   CHEBI:45950;   CHEBI:9523
 xref: Beilstein:13463;   CAS:58-55-9;   DrugBank:DB00277;   Drug_Central:2620;   Gmelin:51226;   HMDB:HMDB0001889;   KEGG:C07130;   KEGG:D00371;   KNApSAcK:C00001510
 xref_mesh: MESH:D013806
 xref: MetaCyc:CPD-12479;   PDBeChem:TEP;   PMID:10796631;   PMID:10836323;   PMID:10893702;   PMID:10921764;   PMID:11126990;   PMID:11170036;   PMID:11200776;   PMID:11261527;   PMID:11408152;   PMID:11826912;   PMID:11848250;   PMID:11941393;   PMID:11949272;   PMID:11950649;   PMID:12531775;   PMID:12836095;   PMID:14517178;   PMID:14713563;   PMID:14988770;   PMID:15005370;   PMID:15042504;   PMID:15202575;   PMID:15317832;   PMID:15356646;   PMID:15483348;   PMID:15739418;   PMID:15829161;   PMID:15902964;   PMID:15908149;   PMID:16083514;   PMID:16651698;   PMID:16930490;   PMID:17130682;   PMID:17207928;   PMID:18307508;   PMID:18800032;   PMID:19559058;   PMID:19727789;   PMID:19845735;   PMID:19888960;   PMID:21467671;   PMID:21796703;   PMID:21834615;   PMID:22377744;   PMID:22541679;   PMID:22541837;   PMID:22702215;   PMID:22770225;   PMID:22771369;   PMID:22836872;   PMID:22909172;   PMID:22915350;   PMID:22981724;   PMID:7302609;   PMID:7389811;   PMID:7656958;   PMID:7767539;   PMID:8730732;   PMID:8960878;   PMID:9256615;   Reaxys:13463;   VSDB:1801;   Wikipedia:Theophylline


show annotations for term's descendants           Sort by:
 
theophylline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd11 abhydrolase domain containing 11 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ABHD11 protein CTD PMID:18951874 NCBI chr12:24,722,277...24,725,760
Ensembl chr12:24,722,283...24,724,997
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase decreases expression ISO Theophylline results in decreased expression of ABL2 mRNA CTD PMID:16083514 NCBI chr13:74,154,533...74,333,244
Ensembl chr13:74,154,835...74,333,244
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ACAA1 protein CTD PMID:18951874 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression EXP Theophylline results in decreased expression of ACADM mRNA CTD PMID:17522070 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acot7 acyl-CoA thioesterase 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ACOT7 protein CTD PMID:18951874 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression EXP Theophylline results in increased expression of ACP5 mRNA; Theophylline results in increased expression of ACP5 protein CTD PMID:26851681 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Theophylline inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16430859 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actr2 actin related protein 2 decreases expression ISO Theophylline results in decreased expression of ACTR2 mRNA CTD PMID:16083514 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Theophylline results in decreased expression of ACTR3 mRNA CTD PMID:16083514 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Adad1 adenosine deaminase domain containing 1 decreases expression ISO Theophylline results in decreased expression of ADAD1 mRNA CTD PMID:18951874 NCBI chr 2:123,790,798...123,848,598
Ensembl chr 2:123,790,915...123,848,179
JBrowse link
G Adamtsl3 ADAMTS-like 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ADAMTSL3 protein CTD PMID:18951874 NCBI chr 1:144,238,958...144,561,065
Ensembl chr 1:144,239,020...144,561,247
JBrowse link
G Adora1 adenosine A1 receptor decreases activity
decreases expression
multiple interactions
EXP Theophylline results in decreased activity of ADORA1 protein
Theophylline results in decreased expression of ADORA1 mRNA
Theophylline binds to and results in decreased activity of ADORA1 protein
CTD PMID:9535120, PMID:12153486, PMID:14992338, PMID:15708489 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Aff4 AF4/FMR2 family, member 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of AFF4 protein CTD PMID:18951874 NCBI chr10:38,692,167...38,773,021
Ensembl chr10:38,692,211...38,773,021
JBrowse link
G Agfg1 ArfGAP with FG repeats 1 increases expression ISO Theophylline results in increased expression of AGFG1 mRNA CTD PMID:18951874 NCBI chr 9:88,607,508...88,663,486
Ensembl chr 9:88,607,508...88,662,224
JBrowse link
G Ahctf1 AT hook containing transcription factor 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of AHCTF1 protein CTD PMID:18951874 NCBI chr13:98,023,528...98,079,138
Ensembl chr13:98,023,430...98,078,946
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression ISO Theophylline results in increased expression of AKT1S1 mRNA CTD PMID:18951874 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Theophylline results in decreased expression of ALDOC mRNA CTD PMID:16083514 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alg9 ALG9, alpha-1,2-mannosyltransferase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ALG9 protein CTD PMID:18951874 NCBI chr 8:55,202,140...55,265,478
Ensembl chr 8:55,202,725...55,265,478
JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A increases expression ISO Theophylline results in increased expression of ANKDD1A mRNA CTD PMID:18951874 NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
JBrowse link
G Ankrd13c ankyrin repeat domain 13C multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ANKRD13C protein CTD PMID:18951874 NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
JBrowse link
G Ankrd44 ankyrin repeat domain 44 increases expression ISO Theophylline results in increased expression of ANKRD44 mRNA CTD PMID:18951874 NCBI chr 9:61,229,252...61,529,532
Ensembl chr 9:61,231,988...61,528,882
JBrowse link
G Aoc1 amine oxidase, copper containing 1 increases activity
decreases expression
EXP
ISO
Theophylline results in increased activity of AOC1 protein
Theophylline results in decreased expression of AOC1 mRNA
CTD PMID:2860926, PMID:18951874 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression EXP Theophylline results in decreased expression of APEX1 mRNA CTD PMID:17522070 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arf1 ADP-ribosylation factor 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARF1 protein CTD PMID:18951874 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Theophylline results in increased expression of ARHGAP15 mRNA CTD PMID:18951874 NCBI chr 3:28,626,987...29,236,225
Ensembl chr 3:28,627,084...29,236,219
JBrowse link
G Arid2 AT-rich interaction domain 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARID2 protein CTD PMID:18951874 NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655
JBrowse link
G Armc8 armadillo repeat containing 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARMC8 protein CTD PMID:18951874 NCBI chr 8:107,723,359...107,819,208
Ensembl chr 8:107,723,359...107,819,050
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ARNT protein CTD PMID:18951874 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arsb arylsulfatase B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ARSB protein CTD PMID:18951874 NCBI chr 2:23,385,154...23,543,028
Ensembl chr 2:23,385,183...23,544,963
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 increases expression ISO Theophylline results in increased expression of ASAP1 mRNA CTD PMID:18951874 NCBI chr 7:104,670,076...104,951,090
Ensembl chr 7:104,669,672...104,801,045
JBrowse link
G Asl argininosuccinate lyase decreases expression EXP Theophylline results in decreased expression of ASL mRNA CTD PMID:17522070 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Atg3 autophagy related 3 increases expression ISO Theophylline results in increased expression of ATG3 mRNA CTD PMID:18951874 NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718
JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ATPAF2 protein CTD PMID:18951874 NCBI chr10:46,768,539...46,783,889
Ensembl chr10:46,768,539...46,783,889
JBrowse link
G Atrx ATRX, chromatin remodeler multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ATRX protein CTD PMID:18951874 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of AURKB protein CTD PMID:18951874 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Azi2 5-azacytidine induced 2 multiple interactions
decreases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of AZI2 protein
Theophylline results in decreased expression of AZI2 mRNA
CTD PMID:18951874 NCBI chr 8:126,411,030...126,435,581
Ensembl chr 8:126,411,829...126,434,579
JBrowse link
G B3galnt2 beta-1,3-N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of B3GALNT2 protein CTD PMID:18951874 NCBI chr17:54,027,859...54,070,399
Ensembl chr17:54,027,859...54,070,399
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of B4GALT7 protein CTD PMID:18951874 NCBI chr17:9,549,605...9,558,672
Ensembl chr17:9,550,028...9,558,634
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BABAM2 protein CTD PMID:18951874 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229
JBrowse link
G Bag5 BAG cochaperone 5 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of BAG5 protein CTD PMID:18951874 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Theophylline co-treated with Cisplatin] results in decreased expression of BCL2 protein; [Theophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein; IL4 protein inhibits the reaction [Theophylline results in decreased expression of BCL2 protein]
Theophylline results in decreased expression of BCL2 mRNA; Theophylline results in decreased expression of BCL2 protein
CTD PMID:8822937, PMID:9312165, PMID:10877050, PMID:10891529, PMID:15313391, PMID:15645133 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl7c BAF chromatin remodeling complex subunit BCL7C multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BCL7C protein CTD PMID:18951874 NCBI chr 1:199,112,192...199,159,125
Ensembl chr 1:199,155,296...199,159,125
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase increases expression ISO Theophylline results in increased expression of BCR mRNA CTD PMID:16083514 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
G Blnk B-cell linker increases expression ISO Theophylline results in increased expression of BLNK mRNA CTD PMID:16083514 NCBI chr 1:260,187,023...260,254,490
Ensembl chr 1:260,186,967...260,254,600
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Theophylline results in decreased expression of BPTF mRNA CTD PMID:18951874 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions EXP [Theophylline results in increased abundance of Cyclic AMP] which results in increased activity of BRAF protein CTD PMID:21693435 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Btbd10 BTB domain containing 10 increases expression ISO Theophylline results in increased expression of BTBD10 mRNA CTD PMID:16083514 NCBI chr 1:178,138,562...178,196,551
Ensembl chr 1:178,138,565...178,196,294
JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of BTG3 protein CTD PMID:18951874 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of C2CD5 protein CTD PMID:18951874 NCBI chr 4:177,245,868...177,331,910
Ensembl chr 4:177,245,868...177,331,915
JBrowse link
G C5 complement C5 multiple interactions ISO Theophylline inhibits the reaction [C5 protein modified form results in increased abundance of Superoxides]; Theophylline promotes the reaction [C5 protein modified form results in increased abundance of Superoxides] CTD PMID:10947063 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Calu calumenin increases expression EXP Theophylline results in increased expression of CALU mRNA CTD PMID:17522070 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression ISO Theophylline results in decreased expression of CAMK2D mRNA CTD PMID:18951874 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CAND1 protein CTD PMID:18951874 NCBI chr 7:62,124,362...62,162,451
Ensembl chr 7:62,124,362...62,162,453
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression ISO Theophylline results in increased expression of CAPRIN1 mRNA CTD PMID:18951874 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO Theophylline results in decreased expression of CAPZA1 mRNA CTD PMID:16083514 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Casp2 caspase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CASP2 protein CTD PMID:18951874 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases activity ISO Theophylline results in increased activity of CASP3 protein CTD PMID:14634331 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP Theophylline inhibits the reaction [Phenylisopropyladenosine results in increased expression of CAT protein] CTD PMID:15792369 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 increases expression ISO Theophylline results in increased expression of CAV1 mRNA CTD PMID:16083514 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccdc130 coiled-coil domain containing 130 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC130 protein CTD PMID:18951874 NCBI chr19:25,367,552...25,378,993
Ensembl chr19:25,367,543...25,378,974
JBrowse link
G Ccdc181 coiled-coil domain containing 181 decreases expression ISO Theophylline results in decreased expression of CCDC181 mRNA CTD PMID:18951874 NCBI chr13:82,574,980...82,588,637
Ensembl chr13:82,574,966...82,588,640
JBrowse link
G Ccdc30 coiled-coil domain containing 30 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC30 protein CTD PMID:18951874 NCBI chr 5:138,364,211...138,462,922
Ensembl chr 5:138,364,167...138,462,864
JBrowse link
G Ccdc82 coiled-coil domain containing 82 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC82 protein CTD PMID:18951874 NCBI chr 8:11,888,460...11,927,920
Ensembl chr 8:11,888,591...11,927,919
JBrowse link
G Ccdc93 coiled-coil domain containing 93 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCDC93 protein CTD PMID:18951874 NCBI chr13:37,400,455...37,473,973
Ensembl chr13:37,400,476...37,468,840
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CCL2 protein CTD PMID:18951874 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO
EXP
[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein
[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein; sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CCND1 protein]
CTD PMID:21693435 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccser2 coiled-coil serine-rich protein 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CCSER2 protein CTD PMID:18951874 NCBI chr16:14,090,547...14,210,512
Ensembl chr16:14,095,058...14,210,449
JBrowse link
G Cd33 CD33 molecule multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CD33 protein CTD PMID:18951874 NCBI chr 1:98,388,811...98,403,539
Ensembl chr 1:98,398,660...98,402,968
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Theophylline results in decreased expression of CD36 mRNA CTD PMID:16083514 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd4 Cd4 molecule decreases expression ISO Theophylline results in decreased expression of CD4 protein CTD PMID:11408767 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cdk13 cyclin-dependent kinase 13 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CDK13 protein CTD PMID:18951874 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO
EXP
[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein
[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein; sorafenib inhibits the reaction [[Theophylline results in increased abundance of Cyclic AMP] which results in increased expression of CDKN1B protein]
CTD PMID:21693435 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Theophylline results in increased expression of CDKN1C mRNA CTD PMID:16083514 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression EXP Theophylline results in decreased expression of CEACAM1 mRNA CTD PMID:17522070 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cenpu centromere protein U multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CENPU protein CTD PMID:18951874 NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
JBrowse link
G Cep290 centrosomal protein 290 decreases expression ISO Theophylline results in decreased expression of CEP290 mRNA CTD PMID:18951874 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Cep63 centrosomal protein 63 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CEP63 protein CTD PMID:18951874 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CEPT1 protein CTD PMID:18951874 NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
JBrowse link
G Cfap97 cilia and flagella associated protein 97 increases expression ISO Theophylline results in increased expression of CFAP97 mRNA CTD PMID:18951874 NCBI chr16:49,280,076...49,329,029
Ensembl chr16:49,280,084...49,318,383
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases stability
increases expression
ISO [Theophylline co-treated with Butyric Acid] results in increased expression of CGA mRNA; Theophylline inhibits the reaction [Butyric Acid results in decreased stability of CGA mRNA]; Theophylline promotes the reaction [Butyric Acid results in increased expression of CGA protein]
Theophylline results in increased stability of CGA mRNA
Theophylline results in increased expression of CGA protein
CTD PMID:1693836, PMID:1693837 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Clec16a C-type lectin domain containing 16A decreases expression ISO Theophylline results in decreased expression of CLEC16A mRNA CTD PMID:18951874 NCBI chr10:5,002,196...5,196,914
Ensembl chr10:5,009,826...5,196,892
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression ISO Theophylline results in decreased expression of CLEC4F mRNA CTD PMID:18951874 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clpb caseinolytic mitochondrial matrix peptidase chaperone subunit B multiple interactions
increases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CLPB protein
Theophylline results in increased expression of CLPB mRNA
CTD PMID:18951874 NCBI chr 1:166,739,372...166,866,095
Ensembl chr 1:166,739,532...166,866,107
JBrowse link
G Clu clusterin increases expression EXP Theophylline results in increased expression of CLU mRNA CTD PMID:17522070 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Theophylline inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] CTD PMID:16430859 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Coq4 coenzyme Q4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of COQ4 protein CTD PMID:18951874 NCBI chr 3:8,349,386...8,357,719
Ensembl chr 3:8,349,185...8,357,871
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of COX5B protein CTD PMID:18951874 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cpm carboxypeptidase M multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CPM protein CTD PMID:18951874 NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
JBrowse link
G Cpne1 copine 1 affects binding ISO Theophylline binds to CPNE1 protein CTD PMID:18951874 NCBI chr 3:151,617,733...151,625,448
NCBI chr 3:152,150,143...152,192,936
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CRELD1 protein CTD PMID:18951874 NCBI chr 4:145,440,284...145,449,894
Ensembl chr 4:145,440,114...145,449,892
JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CRTC3 protein CTD PMID:18951874 NCBI chr 1:142,398,248...142,500,562
Ensembl chr 1:142,393,207...142,500,383
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases expression
ISO [Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Theophylline inhibits the reaction [CSF2 protein results in increased expression of EDN1 mRNA]; Theophylline promotes the reaction [IL1B protein results in increased secretion of CSF2 protein]; trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]]
Theophylline results in decreased expression of CSF2 mRNA
CTD PMID:10374451, PMID:10596698, PMID:12070353 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Theophylline results in increased expression of CSF3 protein CTD PMID:7540958 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csnk1e casein kinase 1, epsilon multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of CSNK1E protein CTD PMID:18951874 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
G Cst3 cystatin C increases expression EXP Theophylline results in increased expression of CST4 mRNA CTD PMID:16651698 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO Theophylline results in decreased expression of CTPS1 mRNA CTD PMID:16083514 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctrl chymotrypsin-like increases expression ISO Theophylline results in increased expression of CTRL mRNA CTD PMID:18951874 NCBI chr19:37,905,864...37,907,714
Ensembl chr19:37,905,864...37,907,714
JBrowse link
G Ctsb cathepsin B increases expression ISO Theophylline results in increased expression of CTSB mRNA CTD PMID:16083514 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsl cathepsin L decreases expression EXP Theophylline results in decreased expression of CTSL mRNA CTD PMID:17522070 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases chemical synthesis
affects response to substance
affects hydroxylation
affects metabolic processing
increases metabolic processing
decreases activity
ISO
EXP
[CYP1A2 protein binds to and results in increased metabolism of Caffeine] which results in increased chemical synthesis of Theophylline; [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]; Fluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of Theophylline]; Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]; zafirlukast inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]
CYP1A2 protein results in increased chemical synthesis of Theophylline
CYP1A2 gene SNP affects the susceptibility to Theophylline
CYP1A2 promoter SNP affects the hydroxylation of Theophylline
CYP1A2 gene SNP affects the metabolism of Theophylline; CYP1A2 protein affects the metabolism of Theophylline
andrographolide affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]; Plant Extracts affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]; rutecarpine promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]
Theophylline results in decreased activity of CYP1A2 protein
CTD PMID:1302044, PMID:9029748, PMID:9701106, PMID:11408986, PMID:11465391, PMID:11483122, PMID:12732846, PMID:15692829, PMID:15720787, PMID:15948934, PMID:15970798, PMID:15985363, PMID:16841220, PMID:20096675, PMID:20797314, PMID:31132250 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP Theophylline results in decreased expression of CYP27A1 protein CTD PMID:26851681 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Theophylline results in decreased expression of CYP2D3 mRNA CTD PMID:17522070 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing
increases chemical synthesis
affects hydroxylation
EXP
ISO
CYP2E1 protein affects the metabolism of Theophylline
CYP2E1 protein results in increased chemical synthesis of Theophylline
CYP2E1 promoter SNP affects the hydroxylation of Theophylline
CTD PMID:1302044, PMID:15948934, PMID:15985363, PMID:16841220 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 decreases expression EXP Theophylline results in decreased expression of CYP2R1 protein CTD PMID:26851681 NCBI chr 1:184,060,521...184,106,604
Ensembl chr 1:184,093,920...184,106,200
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO Theophylline results in decreased expression of CYSLTR1 mRNA CTD PMID:18951874 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DACT3 protein CTD PMID:18951874 NCBI chr 1:78,800,754...78,812,483
Ensembl chr 1:78,800,754...78,812,483
JBrowse link
G Dcbld1 discoidin, CUB and LCCL domain containing 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DCBLD1 protein CTD PMID:18951874 NCBI chr20:33,359,062...33,455,161
Ensembl chr20:33,359,196...33,453,766
JBrowse link
G Ddi2 DNA damage inducible 1 homolog 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DDI2 protein CTD PMID:18951874 NCBI chr 5:160,230,958...160,282,836
Ensembl chr 5:160,230,955...160,282,810
JBrowse link
G Dhx8 DEAH-box helicase 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DHX8 protein CTD PMID:18951874 NCBI chr10:89,645,979...89,683,839
Ensembl chr10:89,645,973...89,683,446
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DLG1 protein CTD PMID:18951874 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Dmac2l distal membrane arm assembly complex 2 like decreases expression ISO Theophylline results in decreased expression of DMAC2L mRNA CTD PMID:18951874 NCBI chr 6:92,057,782...92,076,022
Ensembl chr 6:92,057,807...92,076,021
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DNAJC15 protein CTD PMID:18951874 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DNAJC4 protein CTD PMID:18951874 NCBI chr 1:222,242,889...222,247,115
Ensembl chr 1:222,242,858...222,246,768
JBrowse link
G Dock4 dedicator of cytokinesis 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of DOCK4 protein CTD PMID:18951874 NCBI chr 6:60,374,839...60,782,648
Ensembl chr 6:60,566,196...60,782,556
JBrowse link
G Dolk dolichol kinase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DOLK protein CTD PMID:18951874 NCBI chr 3:8,850,154...8,852,192
Ensembl chr 3:8,850,154...8,852,192
JBrowse link
G Drd5 dopamine receptor D5 increases expression ISO Theophylline results in increased expression of DRD5 mRNA CTD PMID:18951874 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Dusp19 dual specificity phosphatase 19 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of DUSP19 protein CTD PMID:18951874 NCBI chr 3:67,849,966...67,862,475
Ensembl chr 3:67,849,966...67,862,475
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO Theophylline results in increased expression of EARS2 mRNA CTD PMID:18951874 NCBI chr 1:191,997,512...192,025,350
Ensembl chr 1:191,997,512...192,025,350
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Theophylline inhibits the reaction [CSF2 protein results in increased expression of EDN1 mRNA] CTD PMID:10374451 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EGLN3 protein CTD PMID:18951874 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO Theophylline results in decreased expression of SUI1 mRNA CTD PMID:16083514 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression ISO Theophylline results in increased expression of EIF2S3 mRNA CTD PMID:16083514 NCBI chr  X:63,268,106...63,291,125
Ensembl chr  X:63,268,037...63,292,092
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression ISO Theophylline results in increased expression of EIF3A mRNA CTD PMID:16083514 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B increases expression ISO Theophylline results in increased expression of EIF3B mRNA CTD PMID:18951874 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E decreases expression ISO Theophylline results in decreased expression of EIF3E mRNA CTD PMID:16083514 NCBI chr 7:82,997,694...83,037,231 JBrowse link
G Eif4b eukaryotic translation initiation factor 4B increases expression ISO Theophylline results in increased expression of EIF4B mRNA CTD PMID:16083514 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO Theophylline results in decreased expression of EIF5 mRNA CTD PMID:16083514 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ELP6 protein CTD PMID:18951874 NCBI chr 8:118,525,770...118,541,074
Ensembl chr 8:118,525,682...118,541,073
JBrowse link
G Emc3 ER membrane protein complex subunit 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EMC3 protein CTD PMID:18951874 NCBI chr 4:145,471,466...145,487,375
Ensembl chr 4:145,471,454...145,487,426
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ENTPD5 protein CTD PMID:18951874 NCBI chr 6:108,087,677...108,123,811
Ensembl chr 6:108,087,418...108,120,579
JBrowse link
G Epg5 ectopic P-granules autophagy protein 5 homolog multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EPG5 protein CTD PMID:18951874 NCBI chr18:74,299,965...74,397,115
Ensembl chr18:74,299,931...74,395,547
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 decreases expression ISO Theophylline results in decreased expression of EPS15 mRNA CTD PMID:18951874 NCBI chr 5:128,923,809...129,022,268
Ensembl chr 5:128,923,934...129,022,054
JBrowse link
G Eps8l1 EPS8-like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EPS8L1 protein CTD PMID:18951874 NCBI chr 1:72,926,106...72,942,433
Ensembl chr 1:72,927,151...72,941,869
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERCC5 protein CTD PMID:18951874 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Erf Ets2 repressor factor multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERF protein CTD PMID:18951874 NCBI chr 1:82,112,449...82,120,902
Ensembl chr 1:82,112,449...82,120,902
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERGIC1 protein CTD PMID:18951874 NCBI chr10:16,821,393...16,912,050
Ensembl chr10:16,821,880...16,910,641
JBrowse link
G Erlin1 ER lipid raft associated 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERLIN1 protein CTD PMID:18951874 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ERLIN2 protein CTD PMID:18951874 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Evi2b ecotropic viral integration site 2B decreases expression ISO Theophylline results in decreased expression of EVI2B mRNA CTD PMID:16083514 NCBI chr10:66,856,980...66,858,598
Ensembl chr10:66,856,980...66,858,598
JBrowse link
G Exosc3 exosome component 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of EXOSC3 protein CTD PMID:18951874 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc4 exosome component 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of EXOSC4 protein CTD PMID:18951874 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 increases expression ISO Theophylline results in increased expression of EYA3 mRNA CTD PMID:18951874 NCBI chr 5:150,833,754...150,915,390
Ensembl chr 5:150,787,043...150,913,757
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression EXP Theophylline results in increased expression of FABP1 mRNA CTD PMID:17522070 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fads3 fatty acid desaturase 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FADS3 protein CTD PMID:18951874 NCBI chr 1:226,091,774...226,108,332
Ensembl chr 1:226,091,774...226,108,332
JBrowse link
G Fam171b family with sequence similarity 171, member B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FAM171B protein CTD PMID:18951874 NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
JBrowse link
G Fam222b family with sequence similarity 222, member B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FAM222B protein CTD PMID:18951874 NCBI chr10:65,351,245...65,416,869
Ensembl chr10:65,351,245...65,416,869
JBrowse link
G Fbxo8 F-box protein 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FBXO8 protein CTD PMID:18951874 NCBI chr16:37,131,566...37,177,033
Ensembl chr16:37,131,345...37,177,033
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FCHSD2 protein CTD PMID:18951874 NCBI chr 1:166,140,025...166,395,915
Ensembl chr 1:166,125,474...166,395,915
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FDXR protein CTD PMID:18951874 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fga fibrinogen alpha chain increases expression EXP Theophylline results in increased expression of FGA mRNA CTD PMID:17522070 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP Theophylline results in increased expression of FGB mRNA CTD PMID:17522070 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf23 fibroblast growth factor 23 increases expression
multiple interactions
EXP Theophylline results in increased expression of FGF23 protein
Calcifediol inhibits the reaction [Theophylline results in increased expression of FGF23 protein]
CTD PMID:26851681 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fhl3 four and a half LIM domains 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FHL3 protein CTD PMID:18951874 NCBI chr 5:142,688,962...142,696,330
Ensembl chr 5:142,689,026...142,696,383
JBrowse link
G Fibp FGF1 intracellular binding protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FIBP protein CTD PMID:18951874 NCBI chr 1:220,840,078...220,844,412
Ensembl chr 1:220,840,118...220,844,405
JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FIP1L1 protein CTD PMID:18951874 NCBI chr14:36,150,381...36,208,395
Ensembl chr14:36,150,399...36,208,373
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FITM2 protein CTD PMID:18951874 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Flot2 flotillin 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FLOT2 protein CTD PMID:18951874 NCBI chr10:65,304,901...65,329,332
Ensembl chr10:65,304,902...65,329,312
JBrowse link
G Fnbp4 formin binding protein 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNBP4 protein CTD PMID:18951874 NCBI chr 3:79,570,610...79,610,122
Ensembl chr 3:79,570,625...79,610,454
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNTB protein CTD PMID:18951874 NCBI chr 6:99,883,959...99,966,988
Ensembl chr 6:99,883,959...99,966,988
JBrowse link
G Folr1 folate receptor alpha multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FOLR1 protein CTD PMID:18951874 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Theophylline inhibits the reaction [Reserpine results in increased expression of FOS protein] CTD PMID:8577368, PMID:10199625 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxf2 forkhead box F2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FOXF2 protein CTD PMID:18951874 NCBI chr17:34,150,417...34,156,450 JBrowse link
G Foxk2 forkhead box K2 increases expression ISO Theophylline results in increased expression of FOXK2 mRNA CTD PMID:16083514 NCBI chr10:110,468,905...110,518,854
Ensembl chr10:110,469,290...110,518,848
JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like increases expression ISO Theophylline results in increased expression of FSD1L mRNA CTD PMID:18951874 NCBI chr 5:70,441,075...70,517,131
Ensembl chr 5:70,441,123...70,511,659
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GABARAPL1 protein CTD PMID:18951874 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Theophylline results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:11234751 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Theophylline results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:11234751 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Theophylline results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:11234751 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GABRR2 protein CTD PMID:18951874 NCBI chr 5:48,303,366...48,341,571
Ensembl chr 5:48,303,366...48,341,642
JBrowse link
G Gck glucokinase increases expression EXP Theophylline results in increased expression of GCK mRNA CTD PMID:17522070 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein CTD PMID:18951874 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO Theophylline results in increased expression of GFPT1 mRNA CTD PMID:16083514 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GGPS1 protein CTD PMID:18951874 NCBI chr17:53,956,185...53,971,039
Ensembl chr17:53,956,203...53,971,443
JBrowse link
G Gkap1 G kinase anchoring protein 1 increases expression ISO Theophylline results in increased expression of GKAP1 mRNA CTD PMID:18951874 NCBI chr17:6,785,428...6,825,145
Ensembl chr17:6,785,428...6,825,144
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Theophylline results in increased expression of GLRX3 mRNA CTD PMID:18951874 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gls glutaminase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GLS protein CTD PMID:18951874 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression
increases expression
EXP Theophylline results in decreased expression of GNAI1 protein
Theophylline results in increased expression of GNAI1 mRNA
CTD PMID:15708489 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Theophylline results in decreased expression of GNAI2 protein CTD PMID:15708489 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnaq G protein subunit alpha q decreases expression EXP Theophylline results in decreased expression of GNAQ protein CTD PMID:15998294 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gnas GNAS complex locus decreases expression EXP Theophylline results in decreased expression of GNAS protein CTD PMID:15708489 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions
decreases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GNB1 protein
Theophylline results in decreased expression of GNB1 mRNA
CTD PMID:16083514, PMID:18951874 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gpatch8 G patch domain containing 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GPATCH8 protein CTD PMID:18951874 NCBI chr10:90,421,443...90,501,996
Ensembl chr10:90,421,442...90,501,819
JBrowse link
G Gpm6a glycoprotein m6a increases expression ISO Theophylline results in increased expression of GPM6A mRNA CTD PMID:16083514 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Gpr137c G protein-coupled receptor 137C increases expression ISO Theophylline results in increased expression of GPR137C mRNA CTD PMID:18951874 NCBI chr15:19,547,783...19,615,717
Ensembl chr15:19,547,871...19,614,805
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Theophylline results in decreased expression of GPX1 mRNA CTD PMID:17522070 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 multiple interactions
decreases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GRK3 protein
Theophylline results in decreased expression of GRK3 mRNA
CTD PMID:18951874 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grm1 glutamate metabotropic receptor 1 decreases expression EXP Theophylline results in decreased expression of GRM1 protein CTD PMID:15998294 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm6 glutamate metabotropic receptor 6 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of GRM6 protein CTD PMID:18951874 NCBI chr10:36,345,503...36,363,416
Ensembl chr10:36,345,939...36,360,665
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO Theophylline results in increased phosphorylation of GSK3B protein CTD PMID:32001318 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Theophylline inhibits the reaction [Phenylisopropyladenosine results in increased expression of GSR protein] CTD PMID:15792369 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO Theophylline results in decreased expression of GSTM2 mRNA CTD PMID:16083514 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression EXP Theophylline results in decreased expression of GSTM3 mRNA CTD PMID:17522070 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Theophylline results in decreased expression of HADH mRNA CTD PMID:16083514 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hdac1 histone deacetylase 1 increases activity
increases expression
ISO Theophylline results in increased activity of HDAC1 protein
Theophylline results in increased expression of HDAC1 protein
CTD PMID:12070353, PMID:15337792 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO Theophylline results in increased expression of HDAC2 protein CTD PMID:15337792 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac3 histone deacetylase 3 increases activity ISO Theophylline results in increased activity of HDAC3 protein CTD PMID:12070353 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdc histidine decarboxylase affects response to substance ISO HDC protein affects the susceptibility to Theophylline CTD PMID:12893847 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Helq helicase, POLQ-like multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HELQ protein CTD PMID:18951874 NCBI chr14:10,446,981...10,491,042
Ensembl chr14:10,446,993...10,491,190
JBrowse link
G Hemk1 HemK methyltransferase family member 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HEMK1 protein CTD PMID:18951874 NCBI chr 8:116,081,858...116,092,872
Ensembl chr 8:116,082,005...116,092,763
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression EXP Theophylline results in decreased expression of HIBADH mRNA CTD PMID:17522070 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of HINT1 protein CTD PMID:18951874 NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of H2AC18 protein CTD PMID:18951874 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hm13 histocompatibility minor 13 affects binding ISO Theophylline binds to HM13 protein CTD PMID:18951874 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HNRNPH3 protein CTD PMID:18951874 NCBI chr20:27,167,926...27,178,172
Ensembl chr20:27,169,267...27,216,941
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 decreases expression ISO Theophylline results in decreased expression of HPS4 mRNA CTD PMID:18951874 NCBI chr12:50,285,239...50,315,893
Ensembl chr12:50,285,278...50,314,406
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HSD17B14 protein CTD PMID:18951874 NCBI chr 1:101,541,266...101,551,059
Ensembl chr 1:101,541,266...101,551,059
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO Theophylline results in increased expression of HSPA2 mRNA CTD PMID:16083514 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HTRA2 protein CTD PMID:18951874 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Htt huntingtin multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HD protein CTD PMID:18951874 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO Theophylline results in decreased expression of HUS1 mRNA CTD PMID:18951874 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Icam4 intercellular adhesion molecule 4, Landsteiner-Wiener blood group multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ICAM4 protein CTD PMID:18951874 NCBI chr 8:22,047,697...22,048,793
Ensembl chr 8:22,047,697...22,048,793
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ICE2 protein CTD PMID:18951874 NCBI chr 8:75,625,147...75,666,959
Ensembl chr 8:75,625,174...75,666,866
JBrowse link
G Idua alpha-L-iduronidase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IDUA protein CTD PMID:18951874 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Ier2 immediate early response 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IER2 protein CTD PMID:18951874 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifng interferon gamma decreases expression ISO Theophylline results in decreased expression of IFNG mRNA CTD PMID:10596698 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ift122 intraflagellar transport 122 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of IFT122 protein CTD PMID:18951874 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Ift57 intraflagellar transport 57 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IFT57 protein CTD PMID:18951874 NCBI chr11:53,664,638...53,731,779
Ensembl chr11:53,664,638...53,731,779
JBrowse link
G Ift88 intraflagellar transport 88 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of IFT88 protein CTD PMID:18951874 NCBI chr15:37,690,417...37,786,855
Ensembl chr15:37,691,345...37,784,924
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Theophylline results in decreased expression of IGFBP5 mRNA CTD PMID:16083514 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO Theophylline results in increased expression of IHH mRNA CTD PMID:16083514 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Ikbip IKBKB interacting protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of IKBIP protein CTD PMID:18951874 NCBI chr 7:31,784,390...31,803,200
Ensembl chr 7:31,784,438...31,803,194
JBrowse link
G Il10 interleukin 10 decreases secretion ISO Theophylline results in decreased secretion of IL10 protein CTD PMID:11694023 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Theophylline results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:15569413 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions
decreases expression
ISO Theophylline results in decreased expression of [IL12A protein binds to IL12B protein]
Theophylline results in decreased expression of IL12B protein
CTD PMID:15569413 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 decreases expression
decreases secretion
ISO Theophylline results in decreased expression of IL13 mRNA; Theophylline results in decreased expression of IL13 protein
Theophylline results in decreased secretion of IL13 protein
CTD PMID:16083514 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]]; Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] CTD PMID:18951874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
Theophylline inhibits the reaction [Indomethacin results in increased expression of IL1B protein]
[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Budesonide inhibits the reaction [IL1B protein results in increased acetylation of H4-16 protein]]]; Theophylline promotes the reaction [Dexamethasone inhibits the reaction [Hydrogen Peroxide promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]]; Theophylline promotes the reaction [IL1B protein results in increased secretion of CSF2 protein]; trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]]
CTD PMID:12070353, PMID:15337792, PMID:16133968, PMID:18951874 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases secretion ISO Theophylline results in increased secretion of IL2 protein CTD PMID:11694023 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Theophylline results in decreased expression of IL2RA protein CTD PMID:1709825 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il3 interleukin 3 decreases expression ISO Theophylline results in decreased expression of IL3 mRNA CTD PMID:10596698 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
decreases secretion
ISO IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein]; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53]; IL4 protein inhibits the reaction [Theophylline results in decreased expression of BCL2 protein]
Theophylline results in decreased expression of IL4 mRNA
Theophylline results in decreased secretion of IL4 protein
CTD PMID:8822937, PMID:10596698, PMID:11694023 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO [Albuterol co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; [Bucladesine co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; [Dinoprostone co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; [Theophylline co-treated with Albuterol] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Theophylline inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Theophylline inhibits the reaction [TNF protein results in increased expression of IL6 protein]
Theophylline results in increased expression of IL6 mRNA
CTD PMID:11770011, PMID:16083514, PMID:20388727 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Theophylline results in decreased expression of IL6R mRNA CTD PMID:18951874 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer increases expression ISO Theophylline results in increased expression of IL6ST mRNA CTD PMID:16083514 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ilk integrin-linked kinase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ILK protein CTD PMID:18951874 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Inip INTS3 and NABP interacting protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of INIP protein CTD PMID:18951874 NCBI chr 5:77,016,871...77,031,106
Ensembl chr 5:77,019,431...77,031,120
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO Theophylline results in decreased expression of IRF7 mRNA CTD PMID:16083514 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Theophylline results in increased expression of IRS1 mRNA CTD PMID:16083514 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itfg1 integrin alpha FG-GAP repeat containing 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ITFG1 protein CTD PMID:18951874 NCBI chr19:22,281,906...22,403,548
Ensembl chr19:22,281,906...22,403,542
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]]; Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein] CTD PMID:9762784 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO Theophylline results in increased expression of ITGB2 mRNA CTD PMID:16083514 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itm2b integral membrane protein 2B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ITM2B protein CTD PMID:18951874 NCBI chr15:55,254,703...55,277,713
Ensembl chr15:55,254,706...55,277,713
JBrowse link
G Jade1 jade family PHD finger 1 increases expression ISO Theophylline results in increased expression of JADE1 mRNA CTD PMID:18951874 NCBI chr 2:128,461,147...128,514,298
Ensembl chr 2:128,461,224...128,514,291
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of JAK1 protein CTD PMID:18951874 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kcnc3 potassium voltage-gated channel subfamily C member 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of KCNC3 protein CTD PMID:18951874 NCBI chr 1:100,593,453...100,607,874
Ensembl chr 1:100,593,680...100,607,874
JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KCNMB4 protein CTD PMID:18951874 NCBI chr 7:59,461,808...59,514,759
Ensembl chr 7:59,461,799...59,514,939
JBrowse link
G Kdm4b lysine demethylase 4B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KDM4B protein CTD PMID:18951874 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073
JBrowse link
G Kdm6b lysine demethylase 6B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KDM6B protein CTD PMID:18951874 NCBI chr10:56,000,494...56,009,582
Ensembl chr10:56,001,799...56,008,885
JBrowse link
G Kif1b kinesin family member 1B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIF1B protein CTD PMID:18951874 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Kin Kin17 DNA and RNA binding protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of KIN protein CTD PMID:18951874 NCBI chr17:72,198,882...72,216,780
Ensembl chr17:72,198,866...72,209,279
JBrowse link
G Klhl7 kelch-like family member 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of KLHL7 protein CTD PMID:18951874 NCBI chr 4:7,532,881...7,582,032
Ensembl chr 4:7,532,889...7,582,207
JBrowse link
G Krt8 keratin 8 increases expression EXP Theophylline results in increased expression of KRT8 mRNA CTD PMID:17522070 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LAMC1 protein CTD PMID:18951874 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Theophylline results in increased expression of LBP mRNA CTD PMID:17522070 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Letm2 leucine zipper and EF-hand containing transmembrane protein 2 decreases expression ISO Theophylline results in decreased expression of LETM2 mRNA CTD PMID:18951874 NCBI chr16:71,241,335...71,261,841
Ensembl chr16:71,241,335...71,261,840
JBrowse link
G Lgals3 galectin 3 increases expression EXP Theophylline results in increased expression of LGALS3 mRNA CTD PMID:17522070 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 multiple interactions
decreases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LHFPL6 protein
Theophylline results in decreased expression of LHFPL6 mRNA
CTD PMID:18951874 NCBI chr 2:142,262,236...142,461,980
Ensembl chr 2:142,262,236...142,461,980
JBrowse link
G Limk1 LIM domain kinase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LIMK1 protein CTD PMID:18951874 NCBI chr12:25,036,630...25,070,538
Ensembl chr12:25,036,605...25,070,539
JBrowse link
G Lipc lipase C, hepatic type decreases expression EXP Theophylline results in decreased expression of LIPC mRNA CTD PMID:17522070 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
affects localization
increases activity
ISO
EXP
Theophylline inhibits the reaction [Epinephrine results in increased activity of LIPE protein]
Theophylline affects the localization of LIPE protein
Theophylline results in increased activity of LIPE protein
CTD PMID:7155675, PMID:11160373 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G LOC100909485 spindlin-2-like decreases expression EXP Theophylline results in decreased expression of SPIN2B mRNA CTD PMID:17522070 NCBI chr  X:18,340,413...18,342,492
Ensembl chr  X:18,340,688...18,341,467
JBrowse link
G LOC361985 similar to NICE-3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of C1ORF43 protein CTD PMID:18951874 NCBI chr 2:189,400,696...189,413,614
Ensembl chr 2:189,400,696...189,413,608
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Theophylline results in increased expression of LPL mRNA CTD PMID:16083514 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrrc23 leucine rich repeat containing 23 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LRRC23 protein CTD PMID:18951874 NCBI chr 4:157,294,386...157,304,590
Ensembl chr 4:157,294,287...157,304,653
JBrowse link
G Lsm8 LSM8 homolog, U6 small nuclear RNA associated multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of LSM8 protein CTD PMID:18951874 NCBI chr 4:45,555,077...45,560,943
Ensembl chr 4:45,555,077...45,560,943
JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Theophylline results in increased expression of LST1 mRNA CTD PMID:16083514 NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263
JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LTB protein CTD PMID:18951874 NCBI chr20:5,184,631...5,186,476
Ensembl chr20:5,184,515...5,186,503
JBrowse link
G Ltc4s leukotriene C4 synthase decreases secretion ISO Theophylline results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Ltf lactotransferrin decreases expression ISO Theophylline results in decreased expression of LTF protein CTD PMID:12016098 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Lyplal1 lysophospholipase-like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LYPLAL1 protein CTD PMID:18951874 NCBI chr13:104,049,263...104,080,680
Ensembl chr13:104,049,386...104,080,631
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Theophylline results in increased phosphorylation of MAPK1 protein CTD PMID:32001318 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MAPK1IP1L protein CTD PMID:18951874 NCBI chr15:24,078,280...24,100,546
Ensembl chr15:24,078,280...24,101,821
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Theophylline results in increased phosphorylation of MAPK3 protein CTD PMID:32001318 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MAPK7 protein CTD PMID:18951874 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MDH1 protein CTD PMID:18951874 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Mecom MDS1 and EVI1 complex locus increases expression ISO Theophylline results in increased expression of EVI1 mRNA CTD PMID:16083514 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Med13l mediator complex subunit 13L multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of MED13L protein CTD PMID:18951874 NCBI chr12:43,421,317...43,576,859
Ensembl chr12:43,421,308...43,576,804
JBrowse link
G Med16 mediator complex subunit 16 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MED16 protein CTD PMID:18951874 NCBI chr 7:12,619,739...12,632,241
Ensembl chr 7:12,542,713...12,632,298
JBrowse link
G Mef2a myocyte enhancer factor 2a decreases expression ISO Theophylline results in decreased expression of MEF2A mRNA CTD PMID:18951874 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mettl15 methyltransferase like 15 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of METTL15 protein CTD PMID:18951874 NCBI chr 3:100,186,106...100,366,148
Ensembl chr 3:100,183,405...100,364,400
JBrowse link
G Mfsd10 major facilitator superfamily domain containing 10 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MFSD10 protein CTD PMID:18951874 NCBI chr14:81,362,594...81,366,208
Ensembl chr14:81,362,618...81,366,055
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MGST2 protein CTD PMID:18951874 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 decreases expression ISO Theophylline results in decreased expression of MILR1 mRNA CTD PMID:18951874 NCBI chr10:94,944,243...94,961,795
Ensembl chr10:94,944,436...94,961,791
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Theophylline results in increased expression of MITF protein CTD PMID:32001318 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mmab metabolism of cobalamin associated B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MMAB protein CTD PMID:18951874 NCBI chr12:47,920,712...47,935,438
Ensembl chr12:47,920,743...47,935,525
JBrowse link
G Mon1b MON1 homolog B, secretory trafficking associated decreases expression ISO Theophylline results in decreased expression of MON1B mRNA CTD PMID:18951874 NCBI chr19:45,938,433...45,946,647
Ensembl chr19:45,938,915...45,945,741
JBrowse link
G Mosmo modulator of smoothened increases expression ISO Theophylline results in increased expression of MOSMO mRNA CTD PMID:18951874 NCBI chr 1:190,604,613...190,671,906
Ensembl chr 1:190,666,149...190,671,228
JBrowse link
G Mphosph6 M phase phosphoprotein 6 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MPHOSPH6 protein CTD PMID:18951874 NCBI chr19:50,357,314...50,367,137
Ensembl chr19:50,357,338...50,367,187
JBrowse link
G Mpo myeloperoxidase decreases expression
multiple interactions
ISO
EXP
Theophylline results in decreased expression of MPO protein
Theophylline inhibits the reaction [Indomethacin results in increased activity of MPO protein]
CTD PMID:12016098, PMID:16133968 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mtg2 mitochondrial ribosome-associated GTPase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTG2 protein CTD PMID:18951874 NCBI chr 3:175,448,214...175,464,109
Ensembl chr 3:175,450,979...175,464,117
JBrowse link
G Mtif3 mitochondrial translational initiation factor 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTIF3 protein CTD PMID:18951874 NCBI chr12:9,846,355...9,857,548
Ensembl chr12:9,846,398...9,857,548
JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MTO1 protein CTD PMID:18951874 NCBI chr 8:85,807,703...85,832,263
Ensembl chr 8:85,808,125...85,831,937
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming decreases expression ISO Theophylline results in decreased expression of MUC5B mRNA CTD PMID:16083514 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP Theophylline results in decreased expression of MUG1 mRNA CTD PMID:17522070 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
affects expression
increases expression
ISO
EXP
[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein]
Theophylline results in decreased expression of MYC mRNA
Theophylline affects the expression of MYC mRNA
Theophylline results in increased expression of MYC mRNA mutant form; Theophylline results in increased expression of MYC protein
CTD PMID:8416737, PMID:8822937, PMID:17522070 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myo19 myosin XIX multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of MYO19 protein CTD PMID:18951874 NCBI chr10:72,198,475...72,227,892
Ensembl chr10:72,197,977...72,227,462
JBrowse link
G Mzt1 mitotic spindle organizing protein 1 decreases expression ISO Theophylline results in decreased expression of MZT1 mRNA CTD PMID:18951874 NCBI chr15:83,429,437...83,442,118
Ensembl chr15:83,431,178...83,442,008
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of N4BP2L2 protein CTD PMID:18951874 NCBI chr12:627,128...650,604
Ensembl chr12:628,488...650,376
JBrowse link
G Nacc2 NACC family member 2 increases expression ISO Theophylline results in increased expression of NACC2 mRNA CTD PMID:18951874 NCBI chr 3:3,508,084...3,574,787
Ensembl chr 3:3,510,041...3,574,787
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NAPEPLD protein CTD PMID:18951874 NCBI chr 4:9,965,323...10,004,650
Ensembl chr 4:9,966,891...10,002,247
JBrowse link
G Nbeal1 neurobeachin-like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NBEAL1 protein CTD PMID:18951874 NCBI chr 9:66,951,354...67,113,395
Ensembl chr 9:66,952,720...67,110,693
JBrowse link
G Nck2 NCK adaptor protein 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NCK2 protein CTD PMID:18951874 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NDUFB2 protein CTD PMID:18951874 NCBI chr 4:67,378,188...67,385,267
Ensembl chr 4:67,378,188...67,385,266
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase increases expression ISO Theophylline results in increased expression of NEDD4L mRNA CTD PMID:16083514 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Theophylline inhibits the reaction [TNF protein affects the localization of NFKB1 protein] CTD PMID:10344522 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression
decreases degradation
ISO Theophylline affects the expression of NFKBIA protein
Theophylline results in decreased degradation of NFKBIA protein
CTD PMID:11770011, PMID:12065913 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nkapd1 NKAP domain containing 1 increases expression ISO Theophylline results in increased expression of NKAPD1 mRNA CTD PMID:18951874 NCBI chr 8:55,039,731...55,050,259
Ensembl chr 8:55,038,597...55,050,194
JBrowse link
G Nlk nemo like kinase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NLK protein CTD PMID:18951874 NCBI chr10:65,840,052...65,963,932
Ensembl chr10:65,840,052...65,963,932
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NNT protein CTD PMID:18951874 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
G Nop10 NOP10 ribonucleoprotein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NOLA3 protein CTD PMID:18951874 NCBI chr 3:103,747,654...103,748,739
Ensembl chr 3:103,747,654...103,748,739
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Theophylline inhibits the reaction [Indomethacin results in increased expression of NOS2 protein] CTD PMID:16133968 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NQO2 protein CTD PMID:18951874 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO Theophylline results in decreased expression of NREP mRNA CTD PMID:18951874 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nrxn3 neurexin 3 increases expression ISO Theophylline results in increased expression of NRXN3 mRNA CTD PMID:16083514 NCBI chr 6:112,133,204...114,069,589
Ensembl chr 6:112,133,204...114,067,564
JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NSD3 protein CTD PMID:18951874 NCBI chr16:71,126,276...71,237,118
Ensembl chr16:71,130,668...71,237,118
JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 increases expression ISO Theophylline results in increased expression of NSUN4 mRNA CTD PMID:18951874 NCBI chr 5:134,885,377...134,905,492
Ensembl chr 5:134,886,497...134,905,588
JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of NTAQ1 protein CTD PMID:18951874 NCBI chr 7:97,957,022...97,977,158
Ensembl chr 7:97,957,003...97,994,586
JBrowse link
G Nts neurotensin multiple interactions EXP Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA] CTD PMID:10199625 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Nup50 nucleoporin 50 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of NUP50 protein CTD PMID:18951874 NCBI chr 7:125,833,557...125,850,830
Ensembl chr 7:125,833,557...125,850,827
JBrowse link
G Nutf2 nuclear transport factor 2 increases expression ISO Theophylline results in increased expression of NUTF2 mRNA CTD PMID:16083514 NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
JBrowse link
G Ociad1 OCIA domain containing 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of OCIAD1 protein CTD PMID:18951874 NCBI chr14:37,458,023...37,475,485
Ensembl chr14:37,458,029...37,475,418
JBrowse link
G Olr1611 olfactory receptor 1611 increases expression ISO Theophylline results in increased expression of OR4N4 mRNA CTD PMID:18951874 NCBI chr15:27,076,234...27,077,198
Ensembl chr15:27,076,234...27,077,160
JBrowse link
G Osbp oxysterol binding protein increases expression ISO Theophylline results in increased expression of OSBP mRNA CTD PMID:16083514 NCBI chr 1:228,395,237...228,425,366
Ensembl chr 1:228,395,558...228,425,361
JBrowse link
G Otc ornithine carbamoyltransferase decreases expression EXP Theophylline results in decreased expression of OTC mRNA CTD PMID:17522070 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Otp orthopedia homeobox multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of OTP protein; [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of OTP protein CTD PMID:18951874 NCBI chr 2:24,546,393...24,554,953
Ensembl chr 2:24,546,536...24,554,683
JBrowse link
G Pan3 poly(A) specific ribonuclease subunit PAN3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PAN3 protein CTD PMID:18951874 NCBI chr12:9,214,116...9,331,901
Ensembl chr12:9,216,536...9,331,195
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 affects binding
multiple interactions
ISO Theophylline binds to PARP1 protein
[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]
CTD PMID:9454737, PMID:18951874 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pbrm1 polybromo 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PB1 protein CTD PMID:18951874 NCBI chr16:7,103,714...7,202,899
Ensembl chr16:7,103,998...7,200,362
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PCP4L1 protein CTD PMID:18951874 NCBI chr13:89,542,377...89,565,920
Ensembl chr13:89,542,378...89,565,813
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 increases expression ISO Theophylline results in increased expression of PCSK5 mRNA CTD PMID:16083514 NCBI chr 1:236,031,988...236,313,858
Ensembl chr 1:236,031,988...236,313,858
JBrowse link
G Pde3a phosphodiesterase 3A increases expression EXP Theophylline results in increased expression of PDE3A mRNA CTD PMID:16651698 NCBI chr 4:175,431,904...175,703,844
Ensembl chr 4:175,431,904...175,700,238
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PDSS2 protein CTD PMID:18951874 NCBI chr20:47,966,513...48,192,747
Ensembl chr20:47,966,583...48,192,743
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 decreases expression ISO Theophylline results in decreased expression of PEA15 mRNA CTD PMID:16083514 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Pex7 peroxisomal biogenesis factor 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PEX7 protein CTD PMID:18951874 NCBI chr 1:15,311,768...15,374,702
Ensembl chr 1:15,311,770...15,374,850
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIAS1 protein CTD PMID:18951874 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIAS2 protein CTD PMID:18951874 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PICALM protein CTD PMID:18951874 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PIGC protein CTD PMID:18951874 NCBI chr13:79,886,832...79,889,305
Ensembl chr13:79,886,832...79,889,304
JBrowse link
G Pipox pipecolic acid and sarcosine oxidase decreases expression ISO Theophylline results in decreased expression of PIPOX mRNA CTD PMID:18951874 NCBI chr10:64,951,986...64,964,865
Ensembl chr10:64,952,119...64,964,862
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PITPNB protein CTD PMID:18951874 NCBI chr12:51,279,194...51,341,752
Ensembl chr12:51,280,150...51,341,716
JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin decreases expression ISO Theophylline results in decreased expression of PKHD1 mRNA CTD PMID:18951874 NCBI chr 9:26,164,969...26,736,704 JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP Theophylline results in decreased expression of PKLR mRNA CTD PMID:17522070 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions
decreases expression
EXP Theophylline inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]
Theophylline results in decreased expression of PLCB1 protein
CTD PMID:15998294 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Pld3 phospholipase D family, member 3 increases expression ISO Theophylline results in increased expression of PLD3 mRNA CTD PMID:16083514 NCBI chr 1:84,339,269...84,361,686
Ensembl chr 1:84,339,261...84,353,725
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PLEKHA1 protein CTD PMID:18951874 NCBI chr 1:201,429,716...201,481,411
Ensembl chr 1:201,429,771...201,480,877
JBrowse link
G Plrg1 pleiotropic regulator 1 increases expression ISO Theophylline results in increased expression of PLRG1 mRNA CTD PMID:18951874 NCBI chr 2:182,040,338...182,056,669
Ensembl chr 2:182,040,318...182,056,673
JBrowse link
G Polr1b RNA polymerase I subunit B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of POLR1B protein CTD PMID:18951874 NCBI chr 3:121,632,043...121,656,506
Ensembl chr 3:121,632,043...121,656,506
JBrowse link
G Polr2f RNA polymerase II, I and III subunit F multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR2F protein CTD PMID:18951874 NCBI chr 7:120,380,543...120,392,214
Ensembl chr 7:120,380,544...120,390,954
JBrowse link
G Polr3h RNA polymerase III subunit H multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR3H protein CTD PMID:18951874 NCBI chr 7:123,146,248...123,156,558
Ensembl chr 7:123,146,249...123,156,558
JBrowse link
G Polr3k RNA polymerase III subunit K multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of POLR3K protein CTD PMID:18951874 NCBI chr 3:177,374,812...177,379,009
Ensembl chr 3:177,374,812...177,379,008
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP [Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP; INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP] CTD PMID:4306506 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Theophylline results in decreased activity of PON1 protein CTD PMID:31581362 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PPARA protein CTD PMID:18951874 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Theophylline results in increased expression of PPARG mRNA; Theophylline results in increased expression of PPARG protein CTD PMID:16569937 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression ISO Theophylline results in decreased expression of PPP2CA mRNA CTD PMID:16083514 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta decreases expression ISO Theophylline results in decreased expression of PPP3CB mRNA CTD PMID:16083514 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PPP4R3B protein CTD PMID:18951874 NCBI chr14:113,570,150...113,618,138
Ensembl chr14:113,570,150...113,618,138
JBrowse link
G Prim2 DNA primase subunit 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRIM2 protein CTD PMID:18951874 NCBI chr 9:38,535,435...38,745,058
Ensembl chr 9:38,536,920...38,745,099
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases expression ISO Theophylline results in decreased expression of PRKAA1 mRNA CTD PMID:18951874 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PRKACA protein CTD PMID:18951874 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkca protein kinase C, alpha decreases expression ISO Theophylline results in decreased expression of PRKCA mRNA CTD PMID:16083514 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRKRA protein CTD PMID:18951874 NCBI chr 3:63,489,081...63,507,918
Ensembl chr 3:63,489,074...63,507,926
JBrowse link
G Prlr prolactin receptor multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PRLR protein CTD PMID:18951874 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Proser3 proline and serine rich 3 increases expression ISO Theophylline results in increased expression of PROSER3 mRNA CTD PMID:18951874 NCBI chr 1:88,994,552...89,007,808
Ensembl chr 1:88,994,562...89,007,041
JBrowse link
G Prpf38b pre-mRNA processing factor 38B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PRPF38B protein CTD PMID:18951874 NCBI chr 2:211,706,245...211,715,271
Ensembl chr 2:211,706,228...211,715,311
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Theophylline affects the expression of PSMB1 mRNA CTD PMID:16988215 NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 affects expression EXP Theophylline affects the expression of PSMB10 mRNA CTD PMID:16988215 NCBI chr19:37,909,543...37,912,027
Ensembl chr19:37,909,546...37,912,027
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 affects expression EXP Theophylline affects the expression of PSMB2 mRNA CTD PMID:16988215 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 affects expression EXP Theophylline affects the expression of PSMB5 mRNA CTD PMID:16988215 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 affects expression EXP Theophylline affects the expression of PSMB8 mRNA CTD PMID:16988215 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 affects expression EXP Theophylline affects the expression of PSMB9 mRNA CTD PMID:16988215 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Pth parathyroid hormone multiple interactions
increases expression
EXP Calcifediol inhibits the reaction [Theophylline results in increased expression of PTH protein] CTD PMID:26851681 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptma prothymosin alpha decreases expression EXP Theophylline results in decreased expression of PTMA mRNA CTD PMID:17522070 NCBI chr 9:93,545,396...93,549,436
Ensembl chr 9:93,545,396...93,549,436
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 decreases expression ISO Theophylline results in decreased expression of PTP4A1 mRNA CTD PMID:16083514 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 increases expression ISO Theophylline results in increased expression of PTPN2 mRNA CTD PMID:18951874 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Ptpre protein tyrosine phosphatase, receptor type, E increases expression ISO Theophylline results in increased expression of PTPRE mRNA CTD PMID:18951874 NCBI chr 1:207,820,719...207,987,123
Ensembl chr 1:207,887,209...207,987,136
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of PYCR2 protein CTD PMID:18951874 NCBI chr13:99,184,624...99,188,418
Ensembl chr13:99,184,564...99,188,431
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO Theophylline results in increased expression of RAB11B mRNA CTD PMID:18951874 NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
JBrowse link
G Rab21 RAB21, member RAS oncogene family multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RAB21 protein CTD PMID:18951874 NCBI chr 7:58,261,985...58,286,770
Ensembl chr 7:58,261,992...58,286,770
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO Theophylline results in decreased expression of RAD9A mRNA CTD PMID:16083514 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rangrf RAN guanine nucleotide release factor increases expression ISO Theophylline results in increased expression of RANGRF mRNA CTD PMID:18951874 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link
G Rasal2 RAS protein activator like 2 decreases expression ISO Theophylline results in decreased expression of RASAL2 mRNA CTD PMID:18951874 NCBI chr13:74,770,557...75,059,298
Ensembl chr13:74,771,522...75,059,326
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein]; [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RB1 protein CTD PMID:9454737, PMID:18951874 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbm8a RNA binding motif protein 8A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RBM8A protein CTD PMID:18951874 NCBI chr 2:198,755,261...198,758,028
Ensembl chr 2:198,755,262...198,758,028
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RC3H1 protein CTD PMID:18951874 NCBI chr13:78,723,028...78,794,663
Ensembl chr13:78,722,763...78,789,266
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO Theophylline results in increased expression of RCAN1 mRNA CTD PMID:16083514 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rcc1l RCC1 like multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RCC1L protein CTD PMID:18951874 NCBI chr12:25,561,871...25,592,337
Ensembl chr12:25,561,777...25,592,342
JBrowse link
G Rdh10 retinol dehydrogenase 10 increases expression ISO Theophylline results in increased expression of RDH10 mRNA CTD PMID:18951874 NCBI chr 5:2,605,265...2,631,905
Ensembl chr 5:2,603,505...2,632,030
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RECK protein CTD PMID:18951874 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
ISO Theophylline inhibits the reaction [TNF protein results in increased expression of RELA protein]
Theophylline affects the localization of RELA protein
CTD PMID:11770011 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin affects expression ISO Theophylline affects the expression of REN protein CTD PMID:7743391 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Rfk riboflavin kinase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RFK protein CTD PMID:18951874 NCBI chr 1:236,494,221...236,501,733
Ensembl chr 1:236,494,221...236,501,733
JBrowse link
G Rftn1 raftlin lipid raft linker 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RFTN1 protein CTD PMID:18951874 NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
JBrowse link
G Rfx7 regulatory factor X, 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RFX7 protein CTD PMID:18951874 NCBI chr 8:79,159,297...79,279,962
Ensembl chr 8:79,159,370...79,279,962
JBrowse link
G RGD1560289 similar to chromosome 3 open reading frame 20 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of C3ORF20 protein CTD PMID:18951874 NCBI chr 4:123,790,516...123,839,149
Ensembl chr 4:123,801,174...123,837,662
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Theophylline results in increased expression of RGS16 mRNA CTD PMID:16083514 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RHNO1 protein CTD PMID:18951874 NCBI chr 4:161,679,674...161,685,060
Ensembl chr 4:161,680,027...161,681,660
JBrowse link
G Rhot2 ras homolog family member T2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RHOT2 protein CTD PMID:18951874 NCBI chr10:15,205,943...15,211,739
Ensembl chr10:15,205,534...15,211,325
JBrowse link
G Ric3 RIC3 acetylcholine receptor chaperone affects binding ISO Theophylline binds to RIC3 protein CTD PMID:18951874 NCBI chr 1:173,629,218...173,682,226
Ensembl chr 1:173,630,761...173,682,226
JBrowse link
G Riok3 RIO kinase 3 decreases expression ISO Theophylline results in decreased expression of RIOK3 mRNA CTD PMID:16083514 NCBI chr18:3,565,166...3,590,739
Ensembl chr18:3,565,166...3,590,739
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of RIPK3 protein CTD PMID:18951874 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G Rmnd5a required for meiotic nuclear division 5 homolog A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RMND5A protein CTD PMID:18951874 NCBI chr 4:99,249,159...99,305,805
Ensembl chr 4:99,253,633...99,305,812
JBrowse link
G Rnaset2 ribonuclease T2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of RNASET2 protein CTD PMID:18951874 NCBI chr 1:53,174,879...53,192,048
Ensembl chr 1:53,174,879...53,192,048
JBrowse link
G Rps15 ribosomal protein S15 decreases expression ISO Theophylline results in decreased expression of RPS15 mRNA CTD PMID:18951874 NCBI chr 7:12,282,134...12,283,573
Ensembl chr 7:12,282,109...12,283,608
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing decreases expression ISO Theophylline results in decreased expression of SBSPON mRNA CTD PMID:18951874 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Sds serine dehydratase increases expression ISO Theophylline results in increased expression of SDS mRNA CTD PMID:16083514 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Secisbp2 SECIS binding protein 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SECISBP2 protein CTD PMID:18951874 NCBI chr17:13,555,348...13,586,595
Ensembl chr17:13,555,349...13,586,554
JBrowse link
G Sell selectin L multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein]]; Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein] CTD PMID:9762784 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Serpina1 serpin family A member 1 affects response to substance ISO SERPINA1 gene affects the susceptibility to Theophylline CTD PMID:17943569 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase decreases expression ISO Theophylline results in decreased expression of SETD2 mRNA CTD PMID:18951874 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Sftpb surfactant protein B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SFTPB protein CTD PMID:18951874 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sh2d2a SH2 domain containing 2A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SH2D2A protein CTD PMID:18951874 NCBI chr 2:187,218,851...187,225,000
Ensembl chr 2:187,218,851...187,225,002
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SH3RF1 protein CTD PMID:18951874 NCBI chr16:32,062,425...32,227,526
Ensembl chr16:32,062,336...32,227,491
JBrowse link
G Shprh SNF2 histone linker PHD RING helicase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SHPRH protein CTD PMID:18951874 NCBI chr 1:5,240,139...5,313,064
Ensembl chr 1:5,240,180...5,313,054
JBrowse link
G Sike1 suppressor of IKBKE 1 increases expression ISO Theophylline results in increased expression of SIKE1 mRNA CTD PMID:18951874 NCBI chr 2:205,488,182...205,496,013
Ensembl chr 2:205,488,182...205,496,012
JBrowse link
G Sirt2 sirtuin 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SIRT2 protein CTD PMID:18951874 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Slc12a8 solute carrier family 12, member 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLC12A8 protein CTD PMID:18951874 NCBI chr11:70,344,771...70,499,202
Ensembl chr11:70,344,797...70,499,200
JBrowse link
G Slc12a9 solute carrier family 12, member 9 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SLC12A9 protein CTD PMID:18951874 NCBI chr12:22,434,845...22,451,265
Ensembl chr12:22,434,814...22,451,263
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO Theophylline inhibits the reaction [SLC16A1 protein results in increased uptake of Butyrates] CTD PMID:19023563 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc25a24 solute carrier family 25 member 24 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLC25A24 protein CTD PMID:18951874 NCBI chr 2:211,930,371...211,967,511
Ensembl chr 2:211,930,326...211,967,505
JBrowse link
G Slc39a9 solute carrier family 39, member 9 increases expression ISO Theophylline results in increased expression of SLC39A9 mRNA CTD PMID:18951874 NCBI chr 6:104,291,001...104,326,553
Ensembl chr 6:104,291,071...104,329,872
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression ISO Theophylline results in increased expression of SLC5A5 protein CTD PMID:19409042 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression EXP Theophylline results in increased expression of SLCO1B2 mRNA CTD PMID:17522070 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slmap sarcolemma associated protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SLMAP protein CTD PMID:18951874 NCBI chr16:2,112,271...2,227,336
Ensembl chr16:2,112,274...2,227,309
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD2 protein CTD PMID:18951874 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad5 SMAD family member 5 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD5 protein CTD PMID:18951874 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Smim7 small integral membrane protein 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of SMIM7 protein CTD PMID:18951874 NCBI chr16:18,975,746...18,979,664
Ensembl chr16:18,975,746...18,979,651
JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor increases expression ISO Theophylline results in increased expression of SMU1 mRNA CTD PMID:18951874 NCBI chr 5:57,042,301...57,061,379
Ensembl chr 5:57,042,705...57,061,365
JBrowse link
G Snap23 synaptosome associated protein 23 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SNAP23 protein CTD PMID:18951874 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Snx13 sorting nexin 13 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SNX13 protein CTD PMID:18951874 NCBI chr 6:54,487,626...54,591,716
Ensembl chr 6:54,488,038...54,588,778
JBrowse link
G Spats2l spermatogenesis associated, serine-rich 2-like decreases expression ISO Theophylline results in decreased expression of SPATS2L mRNA CTD PMID:18951874 NCBI chr 9:64,643,223...64,843,963
Ensembl chr 9:64,643,281...64,843,960
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Theophylline results in decreased expression of SREBF1 mRNA CTD PMID:17522070 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srr serine racemase decreases expression ISO Theophylline results in decreased expression of SRR mRNA CTD PMID:18951874 NCBI chr10:61,756,138...61,772,327
Ensembl chr10:61,756,138...61,772,293
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SRSF3 protein CTD PMID:18951874 NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
JBrowse link
G Ssr1 signal sequence receptor subunit 1 decreases expression ISO Theophylline results in decreased expression of SSR1 mRNA CTD PMID:16083514 NCBI chr17:27,496,369...27,512,781
Ensembl chr17:27,492,220...27,523,912
JBrowse link
G Ssr3 signal sequence receptor subunit 3 increases expression ISO Theophylline results in increased expression of SSR3 mRNA CTD PMID:18951874 NCBI chr 2:156,010,997...156,023,853
Ensembl chr 2:156,011,002...156,014,527
JBrowse link
G Sst somatostatin increases secretion ISO Theophylline results in increased secretion of SST protein CTD PMID:16601281 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ST3GAL3 protein CTD PMID:18951874 NCBI chr 5:136,765,309...136,965,642
Ensembl chr 5:136,766,208...136,965,191
JBrowse link
G Stam2 signal transducing adaptor molecule 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STAM2 protein CTD PMID:18951874 NCBI chr 3:38,230,676...38,277,433
Ensembl chr 3:38,230,618...38,277,440
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO Theophylline results in increased expression of STAT3 mRNA CTD PMID:16083514 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stk24 serine/threonine kinase 24 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STK24 protein CTD PMID:18951874 NCBI chr15:106,629,258...106,678,917
Ensembl chr15:106,629,312...106,678,918
JBrowse link
G Stk35 serine/threonine kinase 35 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of STK35 protein CTD PMID:18951874 NCBI chr 3:122,307,976...122,340,205
Ensembl chr 3:122,308,025...122,336,468
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor decreases expression ISO Theophylline results in decreased expression of SUPT6H mRNA CTD PMID:16083514 NCBI chr10:65,470,470...65,507,581
Ensembl chr10:65,470,471...65,507,581
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions ISO Theophylline inhibits the reaction [TAC1 protein results in increased secretion of Histamine] CTD PMID:1707400 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Taf1a TATA-box binding protein associated factor, RNA polymerase I subunit A increases expression ISO Theophylline results in increased expression of TAF1A mRNA CTD PMID:18951874 NCBI chr13:101,770,278...101,807,975
Ensembl chr13:101,790,865...101,806,900
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 decreases expression ISO Theophylline results in decreased expression of TAF7 mRNA CTD PMID:16083514 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
G Tars2 threonyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TARS2 protein CTD PMID:18951874 NCBI chr 2:197,861,071...197,881,347
Ensembl chr 2:197,861,115...197,878,142
JBrowse link
G Tas2r103 taste receptor, type 2, member 103 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TAS2R14 protein CTD PMID:18951874 NCBI chr 4:167,179,587...167,203,109
Ensembl chr 4:167,179,718...167,180,656
JBrowse link
G Tbca tubulin folding cofactor A increases expression ISO Theophylline results in increased expression of TBCA mRNA CTD PMID:18951874 NCBI chr 2:24,449,498...24,505,351
Ensembl chr 2:24,449,485...24,505,334
JBrowse link
G Tbxas1 thromboxane A synthase 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TBXAS1 protein CTD PMID:18951874 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tcf3 transcription factor 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TCF3 protein CTD PMID:18951874 NCBI chr 7:12,146,642...12,168,400
Ensembl chr 7:12,144,162...12,168,410
JBrowse link
G Tcn2 transcobalamin 2 increases expression ISO Theophylline results in increased expression of TCN2 mRNA CTD PMID:16083514 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266
JBrowse link
G Tefm transcription elongation factor, mitochondrial multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TEFM protein CTD PMID:18951874 NCBI chr10:67,476,006...67,478,830
Ensembl chr10:67,475,968...67,479,077
JBrowse link
G Tesk1 testis associated actin remodelling kinase 1 increases expression ISO Theophylline results in increased expression of TESK1 mRNA CTD PMID:16083514 NCBI chr 5:58,937,615...58,943,358
Ensembl chr 5:58,937,615...58,943,358
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Theophylline inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Theophylline inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] CTD PMID:16430859 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases expression ISO Theophylline results in increased expression of TGIF1 mRNA CTD PMID:16083514 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP Theophylline results in decreased expression of THRSP mRNA CTD PMID:17522070 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Theophylline results in increased expression of TIMP1 mRNA CTD PMID:17522070 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmc5 transmembrane channel-like 5 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMC5 protein CTD PMID:18951874 NCBI chr 1:188,288,738...188,337,310
Ensembl chr 1:188,278,469...188,337,308
JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMED4 protein CTD PMID:18951874 NCBI chr14:86,390,327...86,395,151
Ensembl chr14:86,390,338...86,395,135
JBrowse link
G Tmem106b transmembrane protein 106B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMEM106B protein CTD PMID:18951874 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tmem19 transmembrane protein 19 decreases expression ISO Theophylline results in decreased expression of TMEM19 mRNA CTD PMID:18951874 NCBI chr 7:58,316,583...58,343,761
Ensembl chr 7:58,316,514...58,343,145
JBrowse link
G Tmem243 transmembrane protein 243 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM243 protein CTD PMID:18951874 NCBI chr 4:21,902,803...21,920,651
Ensembl chr 4:21,902,803...21,920,651
JBrowse link
G Tmem260 transmembrane protein 260 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM260 protein CTD PMID:18951874 NCBI chr15:25,294,452...25,361,623
Ensembl chr15:25,294,425...25,361,623
JBrowse link
G Tmem63a transmembrane protein 63a decreases expression ISO Theophylline results in decreased expression of TMEM63A mRNA CTD PMID:18951874 NCBI chr13:99,219,585...99,253,176
Ensembl chr13:99,220,510...99,253,316
JBrowse link
G Tmem80 transmembrane protein 80 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TMEM80 protein CTD PMID:18951874 NCBI chr 1:214,317,300...214,326,293
Ensembl chr 1:214,317,682...214,326,294
JBrowse link
G Tmem87b transmembrane protein 87B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TMEM87B protein CTD PMID:18951874 NCBI chr 3:121,357,787...121,393,443
Ensembl chr 3:121,358,003...121,393,443
JBrowse link
G Tmx3 thioredoxin-related transmembrane protein 3 increases expression ISO Theophylline results in increased expression of TMX3 mRNA CTD PMID:18951874 NCBI chr18:87,580,227...87,613,481
Ensembl chr18:87,580,424...87,610,390
JBrowse link
G Tnf tumor necrosis factor decreases secretion
multiple interactions
ISO
EXP
Theophylline results in decreased secretion of TNF protein
[Albuterol co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Albuterol promotes the reaction [Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]]; Theophylline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Theophylline inhibits the reaction [TNF protein affects the localization of NFKB1 protein]; Theophylline inhibits the reaction [TNF protein results in increased expression of IL6 protein]; Theophylline inhibits the reaction [TNF protein results in increased expression of RELA protein]; Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]]
Theophylline inhibits the reaction [Indomethacin results in increased expression of TNF protein]; Theophylline inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:8162974, PMID:10344522, PMID:11694023, PMID:11770011, PMID:16133968, PMID:18951874, PMID:20388727 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TNFAIP8 protein CTD PMID:18951874 NCBI chr18:44,664,310...44,779,914
Ensembl chr18:44,716,226...44,779,914
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
ISO
EXP
[Theophylline co-treated with Chlorambucil] results in increased expression of TP53; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53]
Theophylline results in decreased expression of TP53 mRNA
CTD PMID:8822937, PMID:17522070 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpmt thiopurine S-methyltransferase increases expression ISO Theophylline results in increased expression of TPMT mRNA CTD PMID:16083514 NCBI chr17:18,029,090...18,047,716
Ensembl chr17:18,029,124...18,047,714
JBrowse link
G Tpp2 tripeptidyl peptidase 2 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TPP2 protein CTD PMID:18951874 NCBI chr 9:50,664,048...50,744,803
NCBI chr 9:50,578,868...50,628,943
Ensembl chr 9:50,581,234...50,744,803
JBrowse link
G Traf1 TNF receptor-associated factor 1 decreases expression ISO Theophylline results in decreased expression of TRAF1 mRNA CTD PMID:16083514 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
G Trmt10a tRNA methyltransferase 10A multiple interactions
decreases expression
ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TRMT10A protein
Theophylline results in decreased expression of TRMT10A mRNA
CTD PMID:18951874 NCBI chr 2:243,422,811...243,437,533
Ensembl chr 2:243,422,811...243,438,050
JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog increases expression ISO Theophylline results in increased expression of TRMT13 mRNA CTD PMID:18951874 NCBI chr 2:219,615,665...219,628,824
Ensembl chr 2:219,615,420...219,628,997
JBrowse link
G Trmt61a tRNA methyltransferase 61A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TRMT61A protein CTD PMID:18951874 NCBI chr 6:136,150,768...136,156,785
Ensembl chr 6:136,150,785...136,250,752
JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TRPM7 protein CTD PMID:18951874 NCBI chr 3:119,258,189...119,347,084
Ensembl chr 3:119,259,467...119,330,345
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTC3 protein CTD PMID:18951874 NCBI chr11:34,598,324...34,739,986
Ensembl chr11:34,598,492...34,738,791
JBrowse link
G Ttc37 tetratricopeptide repeat domain 37 decreases expression ISO Theophylline results in decreased expression of TTC37 mRNA CTD PMID:18951874 NCBI chr 2:2,891,265...3,037,602
Ensembl chr 2:2,903,492...3,004,553
JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 affects binding ISO Theophylline binds to TTLL3 protein CTD PMID:18951874 NCBI chr 4:145,341,059...145,366,614
Ensembl chr 4:145,342,193...145,365,496
JBrowse link
G Ttn titin multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTN protein CTD PMID:18951874 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of TUBA1B protein CTD PMID:18951874 NCBI chr 7:140,614,746...140,617,721
Ensembl chr 7:140,614,752...140,617,721
JBrowse link
G Tubd1 tubulin, delta 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TUBD1 protein CTD PMID:18951874 NCBI chr10:73,865,828...73,886,976
Ensembl chr10:73,868,943...73,886,669
JBrowse link
G Tusc3 tumor suppressor candidate 3 increases expression ISO Theophylline results in increased expression of TUSC3 mRNA CTD PMID:16083514 NCBI chr16:56,248,125...56,396,491
Ensembl chr16:56,247,659...56,396,502
JBrowse link
G Tyr tyrosinase increases expression ISO Theophylline results in increased expression of TYR mRNA; Theophylline results in increased expression of TYR protein CTD PMID:21071833, PMID:32001318 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Tyrp1 tyrosinase-related protein 1 increases expression ISO Theophylline results in increased expression of TYRP1 protein CTD PMID:32001318 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 affects expression EXP Theophylline affects the expression of UBA1 mRNA CTD PMID:16988215 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 affects expression EXP Theophylline affects the expression of UBE2D3 mRNA CTD PMID:16988215 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Ubfd1 ubiquitin family domain containing 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of UBFD1 protein CTD PMID:18951874 NCBI chr 1:192,025,453...192,040,506
Ensembl chr 1:192,025,357...192,037,025
JBrowse link
G Ubqln2 ubiquilin 2 increases expression ISO Theophylline results in increased expression of UBQLN2 mRNA CTD PMID:16083514 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
G Ubr3 ubiquitin protein ligase E3 component n-recognin 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of UBR3 protein CTD PMID:18951874 NCBI chr 3:56,125,927...56,283,908
Ensembl chr 3:56,125,924...56,281,055
JBrowse link
G Ubtf upstream binding transcription factor multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of UBTF protein CTD PMID:18951874 NCBI chr10:90,250,275...90,265,772
Ensembl chr10:90,250,275...90,265,017
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 affects expression EXP Theophylline affects the expression of UCHL1 mRNA CTD PMID:16988215 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Ufm1 ubiquitin-fold modifier 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of UFM1 protein CTD PMID:18951874 NCBI chr 2:143,096,268...143,104,412
Ensembl chr 2:143,096,271...143,104,412
JBrowse link
G Utp15 UTP15, small subunit processome component increases expression ISO Theophylline results in increased expression of UTP15 mRNA CTD PMID:18951874 NCBI chr 2:28,351,925...28,370,315
Ensembl chr 2:28,353,854...28,370,261
JBrowse link
G Uvrag UV radiation resistance associated multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of UVRAG protein CTD PMID:18951874 NCBI chr 1:163,844,804...164,101,568
Ensembl chr 1:163,844,818...164,101,578
JBrowse link
G Vegfc vascular endothelial growth factor C increases expression ISO Theophylline results in increased expression of VEGFC mRNA CTD PMID:16083514 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
G Vps26a VPS26 retromer complex component A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of VPS26A protein CTD PMID:18951874 NCBI chr20:32,085,465...32,115,310
Ensembl chr20:32,086,746...32,115,357
JBrowse link
G Vps35l VPS35 endosomal protein sorting factor like multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of VPS35L protein CTD PMID:18951874 NCBI chr 1:188,448,517...188,552,268
Ensembl chr 1:188,448,478...188,552,272
JBrowse link
G Vsx1 visual system homeobox 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of VSX1 protein CTD PMID:18951874 NCBI chr 3:146,484,235...146,494,757
Ensembl chr 3:146,484,238...146,491,837
JBrowse link
G Wdr20 WD repeat domain 20 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WDR20 protein CTD PMID:18951874 NCBI chr 6:135,156,984...135,226,425
Ensembl chr 6:135,156,984...135,226,425
JBrowse link
G Wtap WT1 associated protein multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WTAP protein CTD PMID:18951874 NCBI chr 1:47,942,500...47,967,633
Ensembl chr 1:47,942,500...47,967,631
JBrowse link
G Wwox WW domain-containing oxidoreductase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of WWOX protein; [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of WWOX protein CTD PMID:18951874 NCBI chr19:46,761,353...47,695,247 JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Theophylline results in increased expression of XIAP mRNA CTD PMID:18951874 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xylb xylulokinase multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of XYLB protein CTD PMID:18951874 NCBI chr 8:128,041,875...128,076,951
Ensembl chr 8:128,044,084...128,076,946
JBrowse link
G Yap1 Yes1 associated transcriptional regulator decreases expression ISO Theophylline results in decreased expression of YAP1 mRNA CTD PMID:18951874 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Yipf4 Yip1 domain family, member 4 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of YIPF4 protein CTD PMID:18951874 NCBI chr 6:22,126,870...22,138,286
Ensembl chr 6:22,126,870...22,138,286
JBrowse link
G Yipf6 Yip1 domain family, member 6 increases expression ISO Theophylline results in increased expression of YIPF6 mRNA CTD PMID:18951874 NCBI chr  X:68,625,760...68,637,780
Ensembl chr  X:68,626,185...68,637,416
JBrowse link
G Ythdc1 YTH domain containing 1 increases expression ISO Theophylline results in increased expression of YTHDC1 mRNA CTD PMID:18951874 NCBI chr14:22,971,834...23,002,326
Ensembl chr14:22,971,836...23,002,011
JBrowse link
G Zbtb18 zinc finger and BTB domain containing 18 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZBTB18 protein CTD PMID:18951874 NCBI chr13:95,582,234...95,593,316
Ensembl chr13:95,589,668...95,591,236
JBrowse link
G Zbtb25 zinc finger and BTB domain containing 25 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZBTB25 protein CTD PMID:18951874 NCBI chr 6:99,376,415...99,400,834
Ensembl chr 6:99,380,301...99,400,822
JBrowse link
G Zbtb45 zinc finger and BTB domain containing 45 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZBTB45 protein CTD PMID:18951874 NCBI chr 1:65,563,999...65,568,301
Ensembl chr 1:65,564,173...65,568,300
JBrowse link
G Zcchc10 zinc finger CCHC-type containing 10 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZCCHC10 protein CTD PMID:18951874 NCBI chr10:38,664,020...38,674,419 JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 decreases expression ISO Theophylline results in decreased expression of ZDHHC11 mRNA CTD PMID:18951874 NCBI chr 1:31,906,049...31,936,603
Ensembl chr 1:31,906,064...31,936,537
JBrowse link
G Zfand3 zinc finger AN1-type containing 3 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZFAND3 protein CTD PMID:18951874 NCBI chr20:8,693,989...8,892,572
Ensembl chr20:8,696,436...8,892,569
JBrowse link
G Zfp24 zinc finger protein 24 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF24 protein CTD PMID:18951874 NCBI chr18:15,910,175...15,921,757
Ensembl chr18:15,914,399...15,921,734
JBrowse link
G Zfp354a zinc finger protein 354A multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZNF354A protein CTD PMID:18951874 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
G Zfpl1 zinc finger protein-like 1 multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ZFPL1 protein CTD PMID:18951874 NCBI chr 1:221,444,588...221,448,555
Ensembl chr 1:221,443,901...221,448,570
JBrowse link
G Zrsr2 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 decreases expression ISO Theophylline results in decreased expression of ZRSR2 mRNA CTD PMID:18951874 NCBI chr  X:32,304,707...32,327,419
Ensembl chr  X:32,304,757...32,328,364
JBrowse link
G Zxdc ZXD family zinc finger C multiple interactions ISO [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ZXDC protein CTD PMID:18951874 NCBI chr 4:122,282,119...122,314,251
Ensembl chr 4:122,282,279...122,312,879
JBrowse link
aminophylline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Aminophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein CTD PMID:15645133 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cat catalase multiple interactions ISO [Aminophylline co-treated with Photosensitizing Agents] promotes the reaction [Benzo(a)pyrene results in increased expression of CAT protein] CTD PMID:30776357 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Gcg glucagon increases secretion EXP Aminophylline results in increased secretion of GCG protein CTD PMID:1248788 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO [Astemizole binds to and results in decreased activity of HRH1 protein] which affects the susceptibility to Aminophylline CTD PMID:16129921 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        immunomodulator 13689
          theophylline 523
            aminophylline 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteropolycyclic compound 17820
                                    organic heterobicyclic compound 16742
                                      imidazopyrimidine 5437
                                        purines 5435
                                          aminopurine 4393
                                            2-aminopurines 4006
                                              guanine 3970
                                                xanthine 3888
                                                  methylxanthine 1137
                                                    dimethylxanthine 529
                                                      theophylline 523
                                                        aminophylline 4
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.