Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-hydroxytryptophan
go back to main search page
Accession:CHEBI:28171 term browser browse the term
Definition:A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Synonyms:exact_synonym: 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
 related_synonym: 5-HTP;   5-hydroxy-DL-tryptophan;   5-hydroxytryptophan DL-form;   DL-5-HTP;   DL-5-hydroxytryptophan;   Formula=C11H12N2O3;   InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16);   InChIKey=LDCYZAJDBXYCGN-UHFFFAOYSA-N;   SMILES=NC(Cc1c[nH]c2ccc(O)cc12)C(O)=O
 alt_id: CHEBI:20595;   CHEBI:2081
 xref: Beilstein:88199;   CAS:114-03-4;   CAS:56-69-9;   KEGG:C01017;   KNApSAcK:C00001371
 xref_mesh: MESH:D006916
 xref: PMID:14563478;   PMID:15617538;   Reaxys:88199;   Wikipedia:5-Hydroxytryptophan


show annotations for term's descendants           Sort by:
 
5-hydroxytryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase multiple interactions EXP [DDC protein results in decreased carboxylation of 5-Hydroxytryptophan] which results in increased chemical synthesis of Serotonin CTD PMID:32243540 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions EXP [TPH1 protein results in increased hydroxylation of Tryptophan] which results in increased chemical synthesis of 5-Hydroxytryptophan CTD PMID:32243540 NCBI chr 1:102,669,868...102,699,442
Ensembl chr 1:102,669,868...102,699,442
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        molecular messenger 18294
          neurotransmitter 10806
            5-hydroxytryptophan 2
              5-hydroxy-D-tryptophan 0
              5-hydroxy-L-tryptophan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        amino acid 14110
                                          alpha-amino acid 11593
                                            non-proteinogenic alpha-amino acid 1549
                                              hydroxy-amino acid 3
                                                hydroxytryptophan 2
                                                  5-hydroxytryptophan 2
                                                    5-hydroxy-D-tryptophan 0
                                                    5-hydroxy-L-tryptophan 0
paths to the root