Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
go back to main search page
Accession:CHEBI:28125 term browser browse the term
Definition:A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
Synonyms:exact_synonym: (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
 related_synonym: (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid;   22:6(n-3);   22:6-4, 7,10,13,16,19;   4,7,10,13,16,19-Docosahexaenoic acid;   DHA;   Doconexent;   Docosahexaenoic acid;   Formula=C22H32O2;   InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-;   InChIKey=MBMBGCFOFBJSGT-KUBAVDMBSA-N;   SMILES=CC\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/CCC(O)=O;   all-cis-4,7,10,13,16,19-docosahexaenoic acid;   all-cis-DHA;   cervonic acid;   docosa-4,7,10,13,16,19-hexaenoic acid
 alt_id: CHEBI:23857;   CHEBI:43162;   CHEBI:4673
 xref: Beilstein:1715505 "Beilstein";   CAS:6217-54-5 "ChemIDplus";   DrugBank:DB03756;   Drug_Central:4289 "DrugCentral";   HMDB:HMDB0002183;   KEGG:C06429;   LIPID_MAPS_instance:LMFA01030185 "LIPID MAPS";   MetaCyc:CPD-10244;   PDBeChem:HXA;   PMID:12359365 "Europe PMC";   PMID:12538082 "Europe PMC";   PMID:17291553 "Europe PMC";   PMID:18072818 "Europe PMC";   PMID:18220672 "Europe PMC";   PMID:21045096 "Europe PMC";   Reaxys:1715505 "Reaxys";   Wikipedia:Docosahexaenoic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:77016


show annotations for term's descendants       view all columns           Sort by:
 
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgal integrin subunit alpha L JBrowse link 1 198,744,053 198,781,745 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            antineoplastic agent 16561
              all-cis-docosa-4,7,10,13,16,19-hexaenoic acid 16
                (4Z,7Z,10Z,13Z,15E,17R,19Z)-17-hydroperoxydocosahexaenoic acid 0
                (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoic acid 0
                (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid + 16
                (4Z,7Z,10Z,13Z,15E,19Z)-17-oxodocosahexaenoic acid 0
                (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoic acid + 0
                (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoic acid 0
                (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoic acid 0
                (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl group 0
                (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA 0
                (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid 0
                (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoic acid + 0
                (4Z,7Z,10Z,14E,16Z,19Z)-13-oxodocosahexaenoic acid 0
                (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoic acid 0
                (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoic acid 0
                (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoic acid 0
                (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoic acid 0
                (4Z,8E,10Z,13Z,16Z,19Z)-7-oxodocosahexaenoic acid 0
                (7R,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid 0
                (7S,14S)-bis(hydroperoxy)-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoic acid 0
                (7S,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid 0
                (7S,14S)-dihydroxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoic acid 0
                (7S,17S)-bis(hydroperoxy)-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid 0
                1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate 0
                1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                1-(1Z,9Z-octadecadienyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1-(1Z-hexadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                1-(all-cis-docosa-4,7,10,13,16,19-hexaenoyl)-glycerol 0
                1-O-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-N-acetylsphingosine 0
                1-[(11Z)-octadecenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)]-docosahexaenoyl-sn-glycero-3-phosphocholine 0
                1-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-2-hexadecanoyl-sn-glycero-3-phosphocholine 0
                1-[(6Z,9Z,12Z,15Z)-octadecatetraenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                1-[(9Z)-octadecenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                1-eicosanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                1-hexadecyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                1-octadecyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                1-oleoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol 0
                1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate 0
                1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate 0
                1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol 0
                1-tetradecanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                14(S)-HPDHE 0
                14-HPDHE + 0
                2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 0
                21-HDoHE 0
                CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol 0
                N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine 0
                N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine 0
                N-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-L-glutamic acid 0
                cholesteryl (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate 0
                ethyl (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate 0
                lysophosphatidylethanolamine (0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) 0
                lysophosphatidylethanolamine (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        monocarboxylic acid 17254
                                          fatty acid 15818
                                            unsaturated fatty acid 890
                                              polyunsaturated fatty acid 647
                                                essential fatty acid 375
                                                  omega-3 fatty acid 63
                                                    all-cis-docosa-4,7,10,13,16,19-hexaenoic acid 16
                                                      (4Z,7Z,10Z,13Z,15E,17R,19Z)-17-hydroperoxydocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid + 16
                                                      (4Z,7Z,10Z,13Z,15E,19Z)-17-oxodocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoic acid + 0
                                                      (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl group 0
                                                      (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA 0
                                                      (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid 0
                                                      (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoic acid + 0
                                                      (4Z,7Z,10Z,14E,16Z,19Z)-13-oxodocosahexaenoic acid 0
                                                      (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoic acid 0
                                                      (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoic acid 0
                                                      (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoic acid 0
                                                      (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoic acid 0
                                                      (4Z,8E,10Z,13Z,16Z,19Z)-7-oxodocosahexaenoic acid 0
                                                      (7R,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid 0
                                                      (7S,14S)-bis(hydroperoxy)-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoic acid 0
                                                      (7S,14S)-dihydroxy-(4Z,8E,10E,12Z,16Z,19Z)-docosahexaenoic acid 0
                                                      (7S,14S)-dihydroxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoic acid 0
                                                      (7S,17S)-bis(hydroperoxy)-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid 0
                                                      1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate 0
                                                      1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                                                      1-(1Z,9Z-octadecadienyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-(1Z-hexadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                                                      1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                                                      1-(all-cis-docosa-4,7,10,13,16,19-hexaenoyl)-glycerol 0
                                                      1-O-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-N-acetylsphingosine 0
                                                      1-[(11Z)-octadecenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)]-docosahexaenoyl-sn-glycero-3-phosphocholine 0
                                                      1-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-2-hexadecanoyl-sn-glycero-3-phosphocholine 0
                                                      1-[(6Z,9Z,12Z,15Z)-octadecatetraenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                                                      1-[(9Z)-octadecenoyl]-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-eicosanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                                                      1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                                                      1-hexadecyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine 0
                                                      1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine 0
                                                      1-octadecyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-oleoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol 0
                                                      1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate 0
                                                      1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol 0
                                                      1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate 0
                                                      1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol 0
                                                      1-tetradecanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine 0
                                                      14(S)-HPDHE 0
                                                      14-HPDHE + 0
                                                      2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine 0
                                                      21-HDoHE 0
                                                      CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol 0
                                                      N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine 0
                                                      N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine 0
                                                      N-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-L-glutamic acid 0
                                                      cholesteryl (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate 0
                                                      ethyl (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate 0
                                                      lysophosphatidylethanolamine (0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) 0
                                                      lysophosphatidylethanolamine (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.