Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diethanolamine
go back to main search page
Accession:CHEBI:28123 term browser browse the term
Definition:A member of the class of ethanolamines that is ethanolamine having a N-hydroxyethyl substituent.
Synonyms:related_synonym: 2,2'-Iminodiethanol;   Formula=C4H11NO2;   H2dea;   InChI=1S/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H2;   InChIKey=ZBCBWPMODOFKDW-UHFFFAOYSA-N;   N,N-di(hydroxyethyl)amine;   SMILES=OCCNCCO;   bis-(2-hydroxy-ethyl)-amine;   diolamine
 alt_id: CHEBI:23706;   CHEBI:4519
 xref: CAS:111-42-2;   HMDB:HMDB0004437;   KEGG:C06772;   KEGG:D02337;   LINCS:LSM-26236
 xref_mesh: MESH:C020283
 xref: PMID:12571685;   PMID:15304302;   PMID:23567043;   PMID:24275050;   Reaxys:605315;   UM-BBD_compID:c0589;   Wikipedia:Diethanolamine



show annotations for term's descendants           Sort by:
 
diethanolamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death decreases expression ISO
EXP
diethanolamine results in decreased expression of BAD mRNA CTD PMID:16014740 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP
ISO
diethanolamine results in decreased expression of BAX mRNA CTD PMID:16014740 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Casp3 caspase 3 decreases expression
increases activity
ISO
EXP
diethanolamine results in decreased expression of CASP3 mRNA
diethanolamine results in increased activity of CASP3 protein
CTD PMID:16014740 PMID:18948303 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO
EXP
diethanolamine results in increased expression of CCND2 mRNA CTD PMID:16014740 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 increases expression ISO
EXP
diethanolamine results in increased expression of CCNE1 mRNA CTD PMID:16014740 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO
EXP
diethanolamine results in decreased expression of CDKN1A mRNA CTD PMID:16014740 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO
EXP
diethanolamine results in decreased expression of CDKN1B mRNA CTD PMID:16014740 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO
EXP
diethanolamine results in increased expression of E2F1 mRNA CTD PMID:16014740 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Il2 interleukin 2 multiple interactions ISO [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO diethanolamine results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO
EXP
diethanolamine results in decreased expression of TRP53 mRNA
diethanolamine results in decreased expression of TP53 mRNA
CTD PMID:16014740 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      biological role 19757
        biochemical role 19377
          metabolite 19352
            xenobiotic metabolite 14478
              human xenobiotic metabolite 13866
                diethanolamine 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    main group molecular entity 19704
                      s-block molecular entity 19489
                        hydrogen molecular entity 19484
                          hydrides 18841
                            inorganic hydride 17688
                              pnictogen hydride 17669
                                nitrogen hydride 17542
                                  azane 17278
                                    ammonia 17277
                                      organic amino compound 17277
                                        amino alcohol 1034
                                          ethanolamines 800
                                            ethanolamine 77
                                              diethanolamine 11
paths to the root