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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:24,25-dihydrolanosterol
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Accession:CHEBI:28113 term browser browse the term
Definition:A 3beta-sterol formed from lanosterol by reduction across the C-24-C-25 double bond.
Synonyms:exact_synonym: lanost-8-en-3beta-ol
 related_synonym: Formula=C30H52O;   InChI=1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=MBZYKEVPFYHDOH-BQNIITSRSA-N;   Lanostenol;   SMILES=[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCCC(C)C
 alt_id: CHEBI:1303;   CHEBI:19807
 xref: Beilstein:2224904;   CAS:79-62-9;   HMDB:HMDB0006839;   KEGG:C05109;   KNApSAcK:C00023781;   LIPID_MAPS_instance:LMST01010087
 xref_mesh: MESH:C015316
 xref: MetaCyc:CPD-8606;   PMID:898228;   Reaxys:2224904



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24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 decreases abundance ISO CYP51A1 mRNA results in decreased abundance of lanostenol CTD PMID:23125191 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO lanostenol results in decreased activity of HMGCR protein CTD PMID:18024962 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        biochemical role 19640
          metabolite 19623
            eukaryotic metabolite 19326
              plant metabolite 17657
                lanosterol 7
                  24,25-dihydrolanosterol 2
                    eburicol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                organic polycyclic compound 17176
                                  steroid 14380
                                    hydroxy steroid 14096
                                      3-hydroxy steroid 12143
                                        sterol 441
                                          3beta-sterol 435
                                            lanosterol 7
                                              24,25-dihydrolanosterol 2
                                                eburicol + 0
paths to the root