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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:24,25-dihydrolanosterol
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Accession:CHEBI:28113 term browser browse the term
Definition:A 3beta-sterol formed from lanosterol by reduction across the C-24-C-25 double bond.
Synonyms:exact_synonym: lanost-8-en-3beta-ol
 related_synonym: Formula=C30H52O;   InChI=1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=MBZYKEVPFYHDOH-BQNIITSRSA-N;   Lanostenol;   SMILES=[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCCC(C)C
 alt_id: CHEBI:1303;   CHEBI:19807
 xref: Beilstein:2224904;   CAS:79-62-9;   HMDB:HMDB0006839;   KEGG:C05109;   KNApSAcK:C00023781;   LIPID_MAPS_instance:LMST01010087
 xref_mesh: MESH:C015316
 xref: MetaCyc:CPD-8606;   PMID:898228;   Reaxys:2224904



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24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 decreases abundance ISO CYP51A1 mRNA results in decreased abundance of lanostenol CTD PMID:23125191 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO lanostenol results in decreased activity of HMGCR protein CTD PMID:18024962 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      biological role 19773
        biochemical role 19390
          metabolite 19367
            eukaryotic metabolite 19054
              plant metabolite 17458
                lanosterol 7
                  24,25-dihydrolanosterol 2
                    eburicol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic molecule 19572
                              organic cyclic compound 19366
                                organic polycyclic compound 16539
                                  steroid 13056
                                    hydroxy steroid 12658
                                      3-hydroxy steroid 10372
                                        sterol 439
                                          3beta-sterol 433
                                            lanosterol 7
                                              24,25-dihydrolanosterol 2
                                                eburicol + 0
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