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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:borneol
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Accession:CHEBI:28093 term browser browse the term
Definition:A bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2.
Synonyms:exact_synonym: 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
 related_synonym: Borneo camphor;   Formula=C10H18O;   InChI=1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3;   InChIKey=DTGKSKDOIYIVQL-UHFFFAOYSA-N;   SMILES=CC1(C)C2CCC1(C)C(O)C2;   Sumatra camphor;   bornyl alcohol;   endo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol;   endo-2-bornanol;   endo-2-camphanol;   endo-2-hydroxycamphane
 alt_id: CHEBI:22913;   CHEBI:3150
 xref: Beilstein:1903042;   CAS:507-70-0;   Gmelin:185292;   KEGG:C01411;   KNApSAcK:C00003028


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(+)-isoborneol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression		 EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein]; SN50 peptide inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein]
isoborneol results in decreased expression of ABCB1A mRNA; isoborneol results in decreased expression of ABCB1A protein		 CTD PMID:26593909 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP isoborneol results in increased expression of CYP2B1 mRNA CTD PMID:27889497 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO isoborneol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of GPT protein] CTD PMID:33166053 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of IL1B protein] CTD PMID:33166053 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of IL6 protein] CTD PMID:33166053 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased activity of MPO protein] CTD PMID:33166053 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in decreased expression of NFE2L2 protein] CTD PMID:33166053 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of NOS2 protein] CTD PMID:33166053 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in decreased phosphorylation of RELA protein] CTD PMID:33166053 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in decreased expression of SOD1 protein] CTD PMID:33166053 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of TNF protein] CTD PMID:33166053 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of isoborneol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO isoborneol inhibits the reaction [UGT2B7 results in increased susceptibility to Clofibric Acid] CTD PMID:17880178 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        biochemical role 19501
          metabolite 19486
            borneol 17
              (+)-borneol + 0
              (+)-isoborneol 17
              (-)-borneol + 0
              isobornyl formate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    main group molecular entity 19761
                      s-block molecular entity 19612
                        hydrogen molecular entity 19601
                          hydrides 19077
                            organic hydride 18671
                              organic fundamental parent 18671
                                hydrocarbon 18417
                                  terpene 13730
                                    terpenoid 13410
                                      monoterpenoid 1245
                                        bornane monoterpenoid 38
                                          borneol 17
                                            (+)-borneol + 0
                                            (+)-isoborneol 17
                                            (-)-borneol + 0
                                            isobornyl formate 0
paths to the root