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G |
ACHE |
acetylcholinesterase (Yt blood group) |
increases activity multiple interactions |
ISO |
Galactose results in increased activity of ACHE protein catalpol inhibits the reaction [Galactose results in increased activity of ACHE protein]; theaflavin-3,3'-digallate inhibits the reaction [Galactose results in increased activity of ACHE protein] |
CTD |
PMID:23612000 PMID:36638877 |
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NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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G |
AGER |
advanced glycosylation end-product specific receptor |
increases expression multiple interactions decreases expression |
ISO |
Galactose results in increased expression of AGER mRNA; Galactose results in increased expression of AGER protein agomelatine inhibits the reaction [Galactose results in increased expression of AGER protein] Galactose results in decreased expression of AGER protein [Ethanol co-treated with Galactose] results in decreased expression of AGER protein |
CTD |
PMID:22687555 PMID:33516661 PMID:34673010 |
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NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
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G |
AIF1 |
allograft inflammatory factor 1 |
multiple interactions increases expression |
ISO |
lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] agomelatine inhibits the reaction [Galactose results in increased expression of AIF1 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of AIF1 protein] |
CTD |
PMID:28974442 PMID:34673010 |
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NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
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G |
AKR1B1 |
aldo-keto reductase family 1 member B |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of AKR1B1 mRNA protocatechuic acid inhibits the reaction [Galactose results in increased expression of AKR1B1 mRNA] |
CTD |
PMID:22687555 |
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NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
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G |
AOX1 |
aldehyde oxidase 1 |
increases expression multiple interactions |
EXP |
Galactose results in increased expression of AOX1 mRNA sodium bisulfide inhibits the reaction [Galactose results in increased expression of AOX1 mRNA] |
CTD |
PMID:23274001 |
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NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064
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G |
APP |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein] |
CTD |
PMID:35537655 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
AQP4 |
aquaporin 4 |
multiple interactions |
ISO |
[Ethanol co-treated with Galactose] results in decreased expression of AQP4 protein |
CTD |
PMID:33516661 |
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NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
EXP |
[Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of ATF4 protein] |
CTD |
PMID:29427785 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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G |
ATG5 |
autophagy related 5 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of ATG5 mRNA candesartan inhibits the reaction [Galactose results in decreased expression of ATG5 mRNA] |
CTD |
PMID:34906534 |
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NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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G |
ATG7 |
autophagy related 7 |
decreases expression multiple interactions |
ISO EXP |
Galactose results in decreased expression of ATG7 protein MIR34A mRNA promotes the reaction [Galactose results in decreased expression of ATG7 protein] |
CTD |
PMID:28302704 |
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NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
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G |
ATOX1 |
antioxidant 1 copper chaperone |
decreases expression multiple interactions |
EXP |
Galactose results in decreased expression of ATOX1 mRNA sodium bisulfide inhibits the reaction [Galactose results in decreased expression of ATOX1 mRNA] |
CTD |
PMID:23274001 |
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NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532
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G |
ATP5F1A |
ATP synthase F1 subunit alpha |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of ATP5F1A protein |
CTD |
PMID:25997894 |
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NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
Phycocyanin inhibits the reaction [Galactose results in increased expression of BAX protein] agomelatine inhibits the reaction [Galactose results in increased expression of BAX protein]; Galactose promotes the reaction [sodium arsenite results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [Galactose results in increased expression of BAX protein]; Saponins inhibits the reaction [Galactose results in increased expression of BAX protein] Galactose results in increased expression of BAX mRNA; Galactose results in increased expression of BAX protein |
CTD |
PMID:23036742 PMID:25892055 PMID:34673010 PMID:35259467 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
Phycocyanin inhibits the reaction [Galactose results in decreased expression of BCL2 protein] Galactose results in decreased expression of BCL2 mRNA; Galactose results in decreased expression of BCL2 protein agomelatine inhibits the reaction [Galactose results in decreased expression of BCL2 protein]; Galactose promotes the reaction [sodium arsenite results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [Galactose results in decreased expression of BCL2 protein]; Saponins inhibits the reaction [Galactose results in decreased expression of BCL2 protein] |
CTD |
PMID:23036742 PMID:25892055 PMID:34673010 PMID:35259467 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BDNF |
brain derived neurotrophic factor |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of BDNF mRNA; Galactose results in decreased expression of BDNF protein lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein] |
CTD |
PMID:28974442 |
|
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
BECN1 |
beclin 1 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in decreased expression of BECN1 protein]; candesartan inhibits the reaction [Galactose results in decreased expression of BECN1 mRNA] Galactose results in decreased expression of BECN1 mRNA; Galactose results in decreased expression of BECN1 protein |
CTD |
PMID:25997894 PMID:28302704 PMID:34906534 |
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NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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G |
CASP12 |
caspase 12 (gene/pseudogene) |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of CASP12 protein agomelatine inhibits the reaction [Galactose results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of CASP12 protein] |
CTD |
PMID:34673010 |
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NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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G |
CASP3 |
caspase 3 |
increases cleavage increases expression multiple interactions increases activity |
EXP ISO |
Galactose results in increased cleavage of CASP3 protein Galactose results in increased expression of CASP3 mRNA Galactose results in increased expression of CASP3 protein [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of CASP3 protein] albicanol inhibits the reaction [Galactose results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein] Phycocyanin inhibits the reaction [Galactose results in increased cleavage of CASP3 protein] |
CTD |
PMID:23036742 PMID:23795773 PMID:25997894 PMID:32295448 PMID:33761044 PMID:34673010 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP9 protein] Galactose results in increased expression of CASP9 mRNA albicanol inhibits the reaction [Galactose results in increased expression of CASP9 mRNA] Galactose results in increased expression of CASP9 protein |
CTD |
PMID:25997894 PMID:32295448 PMID:33761044 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
multiple interactions decreases activity affects activity increases activity |
ISO |
candesartan inhibits the reaction [Galactose results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Galactose results in increased activity of CAT protein] Galactose affects the activity of CAT protein [Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein; albicanol inhibits the reaction [Galactose results in decreased activity of CAT protein]; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein] |
CTD |
PMID:17211565 PMID:32295448 PMID:33761044 PMID:34906534 PMID:35537655 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCN2 |
cellular communication network factor 2 |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of CCN2 protein Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of CCN2 protein] |
CTD |
PMID:30367734 |
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NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
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G |
CDH5 |
cadherin 5 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of CDH5 protein Ethanol promotes the reaction [Galactose results in decreased expression of CDH5 protein] |
CTD |
PMID:33516661 |
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NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784
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G |
CDK5R1 |
cyclin dependent kinase 5 regulatory subunit 1 |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of CDK5R1 protein gentiopicroside analog inhibits the reaction [Galactose results in increased expression of CDK5R1 protein] |
CTD |
PMID:36878094 |
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NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of CDKN2A protein (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of CDKN2A protein]; Chloroquine inhibits the reaction [(1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of CDKN2A protein]] agomelatine inhibits the reaction [Galactose results in increased expression of CDKN2A protein]; Melatonin inhibits the reaction [Galactose results in increased expression of CDKN2A protein] |
CTD |
PMID:34673010 PMID:36792013 |
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NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
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G |
CHAT |
choline O-acetyltransferase |
multiple interactions decreases activity |
ISO |
catalpol inhibits the reaction [Galactose results in decreased activity of CHAT protein] |
CTD |
PMID:23612000 |
|
NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
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G |
CHRM1 |
cholinergic receptor muscarinic 1 |
multiple interactions decreases expression |
ISO |
catalpol inhibits the reaction [Galactose results in decreased expression of CHRM1 protein] |
CTD |
PMID:23612000 |
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NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
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G |
CTNNB1 |
catenin beta 1 |
multiple interactions decreases expression |
ISO |
gentiopicroside analog inhibits the reaction [Galactose results in decreased expression of CTNNB1 protein] |
CTD |
PMID:36878094 |
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NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression multiple interactions |
EXP |
Galactose results in increased expression of CXCL8 mRNA ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA]; ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein] |
CTD |
PMID:29412148 |
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CYBB |
cytochrome b-245 beta chain |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of CYBB protein agomelatine inhibits the reaction [Galactose results in increased expression of CYBB protein]; Melatonin inhibits the reaction [Galactose results in increased expression of CYBB protein] |
CTD |
PMID:34673010 |
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NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions increases expression |
EXP ISO |
[Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein]; Phycocyanin inhibits the reaction [Galactose results in increased expression of DDIT3 protein] agomelatine inhibits the reaction [Galactose results in increased expression of DDIT3 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of DDIT3 protein] |
CTD |
PMID:23036742 PMID:29427785 PMID:34673010 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DNM1L |
dynamin 1 like |
increases expression multiple interactions |
EXP ISO |
Galactose results in increased expression of DNM1L protein MIR34A mRNA promotes the reaction [Galactose results in increased expression of DNM1L protein] |
CTD |
PMID:28302704 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
ISO |
agomelatine inhibits the reaction [Galactose results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Galactose results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:34673010 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases phosphorylation |
ISO |
agomelatine inhibits the reaction [Galactose results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:34673010 |
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NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
FGF2 |
fibroblast growth factor 2 |
multiple interactions increases expression |
ISO |
Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of FGF2 protein] |
CTD |
PMID:30367734 |
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NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
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G |
GALK1 |
galactokinase 1 |
multiple interactions increases metabolic processing |
EXP |
[GALK1 protein results in increased metabolism of Galactose] which results in increased abundance of galactose-1-phosphate |
CTD |
PMID:20696150 |
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NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
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G |
GAP43 |
growth associated protein 43 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of GAP43 mRNA Quercetin inhibits the reaction [Galactose results in decreased expression of GAP43 mRNA] |
CTD |
PMID:16707173 |
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NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of GCLC mRNA Saponins inhibits the reaction [Galactose results in decreased expression of GCLC mRNA] |
CTD |
PMID:25892055 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GDNF |
glial cell derived neurotrophic factor |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of GDNF mRNA candesartan inhibits the reaction [Galactose results in decreased expression of GDNF mRNA] |
CTD |
PMID:34906534 |
|
NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041
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G |
GFAP |
glial fibrillary acidic protein |
multiple interactions increases expression |
ISO |
agomelatine inhibits the reaction [Galactose results in increased expression of GFAP protein]; Melatonin inhibits the reaction [Galactose results in increased expression of GFAP protein] |
CTD |
PMID:34673010 |
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NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GLB1 |
galactosidase beta 1 |
multiple interactions increases expression |
ISO |
(1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of GLB1 protein]; Chloroquine inhibits the reaction [(1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of GLB1 protein]] |
CTD |
PMID:36792013 |
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NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202
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G |
GLO1 |
glyoxalase I |
multiple interactions |
ISO |
Galactose results in decreased expression of and results in decreased activity of GLO1 protein; protocatechuic acid inhibits the reaction [Galactose results in decreased expression of and results in decreased activity of GLO1 protein] |
CTD |
PMID:22687555 |
|
NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Galactose] results in increased expression of GPT protein; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of GPT protein] |
CTD |
PMID:34416243 |
|
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions decreases expression |
ISO |
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of GPX1 mRNA] |
CTD |
PMID:36638877 |
|
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GRIN1 |
glutamate ionotropic receptor NMDA type subunit 1 |
multiple interactions increases expression |
ISO |
agomelatine inhibits the reaction [Galactose results in increased expression of GRIN1 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of GRIN1 protein] |
CTD |
PMID:34673010 |
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NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
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G |
GRIN2B |
glutamate ionotropic receptor NMDA type subunit 2B |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of GRIN2B protein agomelatine inhibits the reaction [Galactose results in increased expression of GRIN2B protein]; Melatonin inhibits the reaction [Galactose results in increased expression of GRIN2B protein] |
CTD |
PMID:34673010 |
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NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein; gentiopicroside analog inhibits the reaction [Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:36878094 |
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NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSS |
glutathione synthetase |
multiple interactions decreases expression |
EXP |
sodium bisulfide inhibits the reaction [Galactose results in decreased expression of GSS mRNA] |
CTD |
PMID:23274001 |
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NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
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G |
HES1 |
hes family bHLH transcription factor 1 |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein] |
CTD |
PMID:35537655 |
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NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
Galactose affects the reaction [Fusaric Acid affects the expression of HIF1A protein] |
CTD |
PMID:31654802 |
|
NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions decreases expression |
ISO |
Saponins inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA] albicanol inhibits the reaction [Galactose results in decreased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA] |
CTD |
PMID:25892055 PMID:28974442 PMID:33761044 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HSF1 |
heat shock transcription factor 1 |
increases activity |
EXP |
Galactose results in increased activity of HSF1 protein |
CTD |
PMID:34170685 |
|
NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
EXP ISO |
Phycocyanin inhibits the reaction [Galactose results in increased expression of HSPA5 protein] Melatonin inhibits the reaction [Galactose results in increased expression of HSPA5 protein] |
CTD |
PMID:23036742 PMID:34673010 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
IFNB1 |
interferon beta 1 |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased expression of IFNB1 protein; scoparone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased expression of IFNB1 protein] |
CTD |
PMID:23535186 |
|
NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
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G |
IL10 |
interleukin 10 |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein] |
CTD |
PMID:35537655 |
|
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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IL1B |
interleukin 1 beta |
increases expression multiple interactions increases secretion |
ISO |
Galactose results in increased expression of IL1B mRNA; Galactose results in increased expression of IL1B protein [Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein; albicanol inhibits the reaction [Galactose results in increased expression of IL1B mRNA]; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; catalpol inhibits the reaction [Galactose results in increased expression of IL1B protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [Galactose results in increased secretion of IL1B protein] |
CTD |
PMID:22687555 PMID:23612000 PMID:28974442 PMID:29405769 PMID:32295448 PMID:33761044 PMID:35537655 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL6 |
interleukin 6 |
multiple interactions increases expression increases secretion |
ISO EXP |
[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein; [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL6 protein; [Lipopolysaccharides co-treated with Galactose] results in increased expression of IL6 protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; protocatechuic acid inhibits the reaction [Galactose results in increased secretion of IL6 protein]; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of IL6 protein]; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL6 protein] Galactose promotes the reaction [sodium arsenite results in increased expression of IL6 mRNA] Galactose results in increased expression of IL6 mRNA; Galactose results in increased expression of IL6 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Galactose results in increased secretion of IL6 protein]; ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of IL6 protein]; ginsenoside M1 inhibits the reaction [Galactose results in increased secretion of IL6 protein]; ginsenoside Rg3 inhibits the reaction [Galactose results in increased secretion of IL6 protein]; ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein]; ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] |
CTD |
PMID:22687555 PMID:23535186 PMID:29412148 PMID:32295448 PMID:34416243 PMID:35259467 PMID:35537655 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IRF3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased phosphorylation of IRF3 protein; scoparone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased phosphorylation of IRF3 protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of IRF3 mRNA; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IRF3 mRNA] |
CTD |
PMID:23535186 PMID:29405769 |
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NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
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ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
multiple interactions increases expression |
ISO |
agomelatine inhibits the reaction [Galactose results in increased expression of ITPR3 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of ITPR3 protein] |
CTD |
PMID:34673010 |
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NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] affects the localization of and results in increased expression of JUN protein modified form; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of JUN protein modified form] |
CTD |
PMID:23535186 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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KEAP1 |
kelch like ECH associated protein 1 |
multiple interactions increases expression |
ISO |
albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA]; albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] Galactose results in increased expression of KEAP1 mRNA; Galactose results in increased expression of KEAP1 protein |
CTD |
PMID:33761044 |
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NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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LCT |
lactase |
increases hydrolysis |
ISO |
LCT protein results in increased hydrolysis of Galactose |
CTD |
PMID:14701853 |
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NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184
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LRP1 |
LDL receptor related protein 1 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of LRP1 protein [Ethanol co-treated with Galactose] results in decreased expression of LRP1 protein |
CTD |
PMID:33516661 |
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NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
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LRP6 |
LDL receptor related protein 6 |
multiple interactions |
ISO |
[Galactose co-treated with gentiopicroside analog] results in increased expression of LRP6 protein |
CTD |
PMID:36878094 |
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NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044
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MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:30367734 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:30367734 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK8 |
mitogen-activated protein kinase 8 |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of MAPK8 mRNA Galactose promotes the reaction [sodium arsenite results in increased expression of MAPK8 mRNA] |
CTD |
PMID:35259467 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPT |
microtubule associated protein tau |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of MAPT protein gentiopicroside analog inhibits the reaction [Galactose results in increased expression of MAPT protein] |
CTD |
PMID:36878094 |
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NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
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MFN2 |
mitofusin 2 |
increases expression multiple interactions |
EXP ISO |
Galactose results in increased expression of MFN2 protein MIR34A mRNA promotes the reaction [Galactose results in increased expression of MFN2 protein] |
CTD |
PMID:28302704 |
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NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
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MIR34A |
microRNA 34a |
multiple interactions increases expression |
EXP ISO |
MIR34A mRNA promotes the reaction [Galactose results in decreased expression of ATG7 protein]; MIR34A mRNA promotes the reaction [Galactose results in increased expression of DNM1L protein]; MIR34A mRNA promotes the reaction [Galactose results in increased expression of MFN2 protein]; MIR34A mRNA promotes the reaction [Galactose results in increased expression of SQSTM1 protein] Galactose results in increased expression of MIR34A mRNA |
CTD |
PMID:28302704 |
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NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777
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MMP2 |
matrix metallopeptidase 2 |
multiple interactions increases activity |
ISO |
Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased activity of MMP2 protein] |
CTD |
PMID:30367734 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
agomelatine inhibits the reaction [Galactose results in decreased expression of MMP9 protein]; Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of and results in increased activity of MMP9 protein]; Galactose results in increased expression of and results in increased activity of MMP9 protein; Melatonin inhibits the reaction [Galactose results in decreased expression of MMP9 protein] |
CTD |
PMID:30367734 PMID:34673010 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MT-CO1 |
mitochondrially encoded cytochrome c oxidase I |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of COX1 protein |
CTD |
PMID:25997894 |
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NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
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MT-ND4 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 |
affects metabolic processing |
EXP |
ND4 protein affects the metabolism of Galactose |
CTD |
PMID:8662757 |
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NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137
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MT-ND6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
affects metabolic processing |
ISO |
ND6 protein affects the metabolism of Galactose |
CTD |
PMID:9707444 |
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NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673
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MYD88 |
MYD88 innate immune signal transduction adaptor |
multiple interactions |
ISO |
[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of MYD88 protein; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of MYD88 protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of MYD88 mRNA; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of MYD88 mRNA] |
CTD |
PMID:23535186 PMID:29405769 |
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NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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NDUFB8 |
NADH:ubiquinone oxidoreductase subunit B8 |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of NDUFB8 protein |
CTD |
PMID:25997894 |
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NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000
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NFE2L2 |
NFE2 like bZIP transcription factor 2 |
affects localization decreases expression multiple interactions |
ISO |
Galactose affects the localization of NFE2L2 protein Galactose results in decreased expression of NFE2L2 mRNA; Galactose results in decreased expression of NFE2L2 protein albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 protein]; theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA] Saponins inhibits the reaction [Galactose affects the localization of NFE2L2 protein] |
CTD |
PMID:25892055 PMID:33761044 PMID:36638877 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKB1 |
nuclear factor kappa B subunit 1 |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of NFKB1 mRNA; Galactose results in increased expression of NFKB1 protein Galactose promotes the reaction [sodium arsenite results in increased expression of NFKB1 mRNA] |
CTD |
PMID:22687555 PMID:35259467 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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NOS2 |
nitric oxide synthase 2 |
multiple interactions increases expression increases activity |
ISO |
Oligopeptides inhibits the reaction [Galactose results in increased activity of NOS2 protein] Galactose results in increased expression of NOS2 mRNA |
CTD |
PMID:23796539 PMID:28974442 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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NOTCH1 |
notch receptor 1 |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] |
CTD |
PMID:35537655 |
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NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
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NOX4 |
NADPH oxidase 4 |
multiple interactions increases expression |
ISO |
agomelatine inhibits the reaction [Galactose results in increased expression of NOX4 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of NOX4 protein] |
CTD |
PMID:34673010 |
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NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
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NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions decreases expression |
ISO |
Saponins inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] albicanol inhibits the reaction [Galactose results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] |
CTD |
PMID:25892055 PMID:28974442 PMID:33761044 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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OAT |
ornithine aminotransferase |
multiple interactions |
ISO |
Galactose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] |
CTD |
PMID:2827574 |
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NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976
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OCLN |
occludin |
decreases expression |
ISO |
Galactose results in decreased expression of OCLN protein |
CTD |
PMID:33516661 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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PDK1 |
pyruvate dehydrogenase kinase 1 |
multiple interactions |
EXP |
Galactose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] |
CTD |
PMID:31654802 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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PKM |
pyruvate kinase M1/2 |
multiple interactions |
EXP |
Galactose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA] |
CTD |
PMID:31654802 |
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NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
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PLAU |
plasminogen activator, urokinase |
multiple interactions increases expression |
ISO |
Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of PLAU protein] |
CTD |
PMID:30367734 |
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NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
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PPARGC1A |
PPARG coactivator 1 alpha |
decreases expression |
ISO |
Galactose results in decreased expression of PPARGC1A protein |
CTD |
PMID:28302704 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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PRDX2 |
peroxiredoxin 2 |
multiple interactions decreases expression |
ISO |
theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of PRDX2 mRNA] |
CTD |
PMID:36638877 |
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NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
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PSENEN |
presenilin enhancer, gamma-secretase subunit |
multiple interactions increases expression |
ISO |
gentiopicroside analog inhibits the reaction [Galactose results in increased expression of PSENEN protein] |
CTD |
PMID:36878094 |
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NCBI chr19:35,745,651...35,747,519
Ensembl chr19:35,745,600...35,747,519
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PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
Galactose results in increased expression of and results in increased activity of PTGS2 protein; lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 protein] |
CTD |
PMID:22687555 PMID:28974442 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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RBPJ |
recombination signal binding protein for immunoglobulin kappa J region |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein] |
CTD |
PMID:35537655 |
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NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131
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RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization increases expression |
ISO EXP |
[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein; [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of RELA protein; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; Galactose results in increased expression of and results in increased activity of RELA protein; protocatechuic acid inhibits the reaction [Galactose results in increased expression of and results in increased activity of RELA protein]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA protein]; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of RELA protein] Galactose affects the localization of RELA protein ginsenoside F1 inhibits the reaction [Galactose affects the localization of RELA protein]; SB 203580 inhibits the reaction [Galactose affects the localization of RELA protein] Galactose results in increased expression of RELA mRNA; Galactose results in increased expression of RELA protein |
CTD |
PMID:22687555 PMID:23535186 PMID:29412148 PMID:35537655 |
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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REST |
RE1 silencing transcription factor |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of REST protein gentiopicroside analog inhibits the reaction [Galactose results in decreased expression of REST protein] |
CTD |
PMID:36878094 |
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NCBI chr 4:56,907,900...56,935,844
Ensembl chr 4:56,907,876...56,966,808
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RNF31 |
ring finger protein 31 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Galactose] results in increased expression of RNF31 protein; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of GPT protein]; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of IL6 protein]; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of TNF protein]; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of TNFAIP3 protein] |
CTD |
PMID:34416243 |
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NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660
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SIRT1 |
sirtuin 1 |
multiple interactions decreases expression |
ISO EXP |
Saponins inhibits the reaction [Galactose results in decreased expression of SIRT1 protein] [Glucose deficiency co-treated with Galactose co-treated with Amino Acids co-treated with Pyruvic Acid] inhibits the reaction [resveratrol results in increased expression of SIRT1 protein] |
CTD |
PMID:25892055 PMID:27358235 PMID:29426000 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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SLC2A2 |
solute carrier family 2 member 2 |
increases transport |
EXP |
SLC2A2 protein results in increased transport of Galactose |
CTD |
PMID:8457197 |
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NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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SLC2A3 |
solute carrier family 2 member 3 |
multiple interactions increases transport |
EXP |
Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Galactose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Galactose] |
CTD |
PMID:8457197 |
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NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007
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SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions affects transport |
EXP |
Galactose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] SLC5A1 protein affects the transport of Galactose |
CTD |
PMID:16300400 PMID:17288452 |
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NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029
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SOD1 |
superoxide dismutase 1 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of SOD1 mRNA theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of SOD1 mRNA] |
CTD |
PMID:36638877 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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SOD2 |
superoxide dismutase 2 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of SOD2 mRNA albicanol inhibits the reaction [Galactose results in decreased expression of SOD2 protein] Saponins inhibits the reaction [Galactose results in decreased expression of SOD2 mRNA] |
CTD |
PMID:25892055 PMID:33761044 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SORD |
sorbitol dehydrogenase |
increases expression |
ISO |
Galactose results in increased expression of SORD mRNA |
CTD |
PMID:22687555 |
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NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185
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G |
SP1 |
Sp1 transcription factor |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of SP1 protein Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of SP1 protein] |
CTD |
PMID:30367734 |
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NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
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G |
SQSTM1 |
sequestosome 1 |
increases expression multiple interactions |
EXP ISO |
Galactose results in increased expression of SQSTM1 protein (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [(1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]] Hydroxychloroquine inhibits the reaction [Metformin inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]]; Metformin inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]; MIR34A mRNA promotes the reaction [Galactose results in increased expression of SQSTM1 protein] |
CTD |
PMID:28302704 PMID:29426000 PMID:36792013 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
ISO |
Galactose results in increased expression of SREBF1 mRNA |
CTD |
PMID:10913129 |
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NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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G |
TFAM |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of TFAM protein |
CTD |
PMID:25997894 |
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NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
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G |
TFEB |
transcription factor EB |
affects localization multiple interactions |
ISO |
Galactose affects the localization of TFEB protein (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one inhibits the reaction [Galactose affects the localization of TFEB protein] |
CTD |
PMID:36792013 |
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NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
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G |
TGFB1 |
transforming growth factor beta 1 |
increases expression multiple interactions |
ISO |
Galactose results in increased expression of TGFB1 protein Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of TGFB1 protein] |
CTD |
PMID:30367734 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TICAM1 |
TIR domain containing adaptor molecule 1 |
multiple interactions |
ISO |
[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TICAM1 protein; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TICAM1 protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of TICAM1 mRNA; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TICAM1 mRNA] |
CTD |
PMID:23535186 PMID:29405769 |
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NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
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G |
TJP1 |
tight junction protein 1 |
decreases expression multiple interactions |
ISO |
Galactose results in decreased expression of TJP1 protein Ethanol promotes the reaction [Galactose results in decreased expression of TJP1 protein] |
CTD |
PMID:33516661 |
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NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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G |
TLR2 |
toll like receptor 2 |
multiple interactions |
ISO |
[Galactose co-treated with Aluminum Chloride] results in increased expression of TLR2 mRNA; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TLR2 mRNA] |
CTD |
PMID:29405769 |
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NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
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G |
TLR4 |
toll like receptor 4 |
multiple interactions |
ISO |
[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of TLR4 mRNA; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TLR4 mRNA] |
CTD |
PMID:23535186 PMID:29405769 |
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TNF |
tumor necrosis factor |
multiple interactions increases expression increases secretion |
ISO |
[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein; [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Galactose] results in increased expression of TNF protein; albicanol inhibits the reaction [Galactose results in increased expression of TNF mRNA]; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; catalpol inhibits the reaction [Galactose results in increased expression of TNF protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; protocatechuic acid inhibits the reaction [Galactose results in increased secretion of TNF protein]; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of TNF protein]; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein] [Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein; candesartan inhibits the reaction [Galactose results in increased expression of TNF mRNA]; Galactose promotes the reaction [sodium arsenite results in increased expression of TNF mRNA]; thymoquinone inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein] Galactose results in increased expression of TNF mRNA; Galactose results in increased expression of TNF protein |
CTD |
PMID:22687555 PMID:23535186 PMID:23612000 PMID:28974442 PMID:29405769 PMID:33761044 PMID:34416243 PMID:34906534 PMID:35259467 PMID:35537655 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP3 |
TNF alpha induced protein 3 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Galactose] results in increased expression of TNFAIP3 protein; RNF31 protein affects the reaction [[Lipopolysaccharides co-treated with Galactose] results in increased expression of TNFAIP3 protein] |
CTD |
PMID:34416243 |
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NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
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G |
TP53 |
tumor protein p53 |
multiple interactions increases expression |
EXP ISO |
Phycocyanin inhibits the reaction [Galactose results in increased expression of TP53 protein] [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] |
CTD |
PMID:23036742 PMID:25997894 PMID:29426000 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TXNIP |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP |
Galactose results in increased expression of TXNIP protein Hydroxychloroquine inhibits the reaction [Metformin inhibits the reaction [Galactose results in increased expression of TXNIP protein]]; Metformin inhibits the reaction [Galactose results in increased expression of TXNIP protein] |
CTD |
PMID:29426000 |
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NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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G |
TXNRD1 |
thioredoxin reductase 1 |
decreases expression multiple interactions |
EXP |
Galactose results in decreased expression of TXNRD1 mRNA sodium bisulfide inhibits the reaction [Galactose results in decreased expression of TXNRD1 mRNA] |
CTD |
PMID:23274001 |
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NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
increases expression |
EXP |
KRN 7000 results in increased expression of CXCL10 protein |
CTD |
PMID:15867097 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
IL12B |
interleukin 12B |
increases expression |
EXP |
KRN 7000 results in increased expression of IL12B protein |
CTD |
PMID:15867097 |
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NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
GALK1 |
galactokinase 1 |
multiple interactions |
EXP |
[Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein] which results in decreased abundance of galactose-1-phosphate; [GALK1 protein results in increased metabolism of Galactose] which results in increased abundance of galactose-1-phosphate |
CTD |
PMID:20696150 |
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NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
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