Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:28052 term browser browse the term
Definition:An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group.
Synonyms:exact_synonym: 4-acetyl-N-(cyclohexylcarbamoyl)benzene-1-sulfonamide
 related_synonym: 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea;   4-Acetyl-N-((cyclohexylamino)carbonyl)benzenesulfonamide;   Dymelor;   Formula=C15H20N2O4S;   InChI=1S/C15H20N2O4S/c1-11(18)12-7-9-14(10-8-12)22(20,21)17-15(19)16-13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H2,16,17,19);   InChIKey=VGZSUPCWNCWDAN-UHFFFAOYSA-N;   N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea;   SMILES=CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1;   acetohexamida;   acetohexamidum
 alt_id: CHEBI:22175;   CHEBI:2395
 xref: Beilstein:2225115;   CAS:968-81-0;   DrugBank:DB00414;   Drug_Central:57;   HMDB:HMDB0014558;   KEGG:C06806;   KEGG:D00219;   LINCS:LSM-5638
 xref_mesh: MESH:D000092
 xref: PMID:13945057;   PMID:2699749;   PMID:8070312;   PMID:910864;   Reaxys:2225115;   Wikipedia:Acetohexamide

show annotations for term's descendants           Sort by:
acetohexamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Acetohexamide binds to ALB protein; Acetohexamide binds to ALB protein modified form CTD PMID:20435530 PMID:20829128 PMID:20956006 PMID:20974553 PMID:21612784 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Acetohexamide CTD PMID:25451588 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      application 19401
        pharmaceutical 19289
          drug 19289
            hypoglycemic agent 4048
              acetohexamide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        carboacyl group 17410
                                          univalent carboacyl group 17410
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                monocarboxylic acid amide 14600
                                                  urea 5020
                                                    ureas 5018
                                                      N-sulfonylurea 120
                                                        acetohexamide 2
paths to the root