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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose 1,6-bisphosphate
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Accession:CHEBI:28013 term browser browse the term
Definition:A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.
Synonyms:exact_synonym: beta-D-fructofuranose 1,6-bis(dihydrogen phosphate)
 related_synonym: 1,6-di-O-phosphono-beta-D-fructofuranose;   BETA FRUCTOSE 1,6-DIPHOSPHATE;   Formula=C6H14O12P2;   Fosfructose;   InChI=1S/C6H14O12P2/c7-4-3(1-16-19(10,11)12)18-6(9,5(4)8)2-17-20(13,14)15/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6-/m1/s1;   InChIKey=RNBGYGVWRKECFJ-ARQDHWQXSA-N;   SMILES=O[C@H]1[C@H](O)[C@@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O;   beta-D-Fructose 1,6-bisphosphate
 alt_id: CHEBI:10374;   CHEBI:22767;   CHEBI:41014;   CHEBI:42553
 xref: Beilstein:1690982;   CAS:488-69-7;   DrugBank:DB04551;   KEGG:C05378
 xref_mesh: MESH:C029063
 xref: PDBeChem:FBP;   Reaxys:1690982
 cyclic_relationship: is_conjugate_acid_of CHEBI:32966


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beta-D-fructofuranose 1,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22227475 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22227475 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases degradation
ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
fructose-1,6-diphosphate results in decreased degradation of NOS2 mRNA
CTD PMID:22227475 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19767
    role 19714
      biological role 19714
        biochemical role 19303
          metabolite 19285
            fundamental metabolite 12677
              D-fructose 1,6-bisphosphate 5
                D-fructofuranose 1,6-bisphosphate 5
                  beta-D-fructofuranose 1,6-bisphosphate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      chalcogen 19386
                        oxygen atom 19349
                          oxygen molecular entity 19349
                            hydroxides 19075
                              oxoacid 18277
                                pnictogen oxoacid 10311
                                  phosphorus oxoacid 9234
                                    phosphoric acids 7954
                                      phosphoric acid 7954
                                        phosphoric acid derivative 7634
                                          phosphate 7634
                                            organic phosphate 7633
                                              carbohydrate phosphate 1716
                                                phospho sugar 1641
                                                  ketose phosphate 8
                                                    ketohexose phosphate 6
                                                      ketohexose bisphosphate 6
                                                        D-fructose 1,6-bisphosphate 5
                                                          D-fructofuranose 1,6-bisphosphate 5
                                                            beta-D-fructofuranose 1,6-bisphosphate 5
paths to the root