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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose 1,6-bisphosphate
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Accession:CHEBI:28013 term browser browse the term
Definition:A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.
Synonyms:exact_synonym: beta-D-fructofuranose 1,6-bis(dihydrogen phosphate)
 related_synonym: 1,6-di-O-phosphono-beta-D-fructofuranose;   BETA FRUCTOSE 1,6-DIPHOSPHATE;   Formula=C6H14O12P2;   Fosfructose;   InChI=1S/C6H14O12P2/c7-4-3(1-16-19(10,11)12)18-6(9,5(4)8)2-17-20(13,14)15/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6-/m1/s1;   InChIKey=RNBGYGVWRKECFJ-ARQDHWQXSA-N;   SMILES=O[C@H]1[C@H](O)[C@@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O;   beta-D-Fructose 1,6-bisphosphate
 alt_id: CHEBI:10374;   CHEBI:22767;   CHEBI:41014;   CHEBI:42553
 xref: Beilstein:1690982;   CAS:488-69-7;   DrugBank:DB04551;   KEGG:C05378
 xref_mesh: MESH:C029063
 xref: PDBeChem:FBP;   Reaxys:1690982
 cyclic_relationship: is_conjugate_acid_of CHEBI:32966


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beta-D-fructofuranose 1,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22227475 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22227475 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases degradation
ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
fructose-1,6-diphosphate results in decreased degradation of NOS2 mRNA
CTD PMID:22227475 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            fundamental metabolite 12625
              D-fructose 1,6-bisphosphate 5
                D-fructofuranose 1,6-bisphosphate 5
                  beta-D-fructofuranose 1,6-bisphosphate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              oxoacid 18235
                                pnictogen oxoacid 10181
                                  phosphorus oxoacid 9072
                                    phosphoric acids 7831
                                      phosphoric acid 7831
                                        phosphoric acid derivative 7511
                                          phosphate 7511
                                            organic phosphate 7510
                                              carbohydrate phosphate 1536
                                                phospho sugar 1462
                                                  ketose phosphate 8
                                                    ketohexose phosphate 6
                                                      ketohexose bisphosphate 6
                                                        D-fructose 1,6-bisphosphate 5
                                                          D-fructofuranose 1,6-bisphosphate 5
                                                            beta-D-fructofuranose 1,6-bisphosphate 5
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