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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-fructofuranose 1,6-bisphosphate
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Accession:CHEBI:28013 term browser browse the term
Definition:A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.
Synonyms:exact_synonym: beta-D-fructofuranose 1,6-bis(dihydrogen phosphate)
 related_synonym: 1,6-di-O-phosphono-beta-D-fructofuranose;   BETA FRUCTOSE 1,6-DIPHOSPHATE;   Formula=C6H14O12P2;   Fosfructose;   InChI=1S/C6H14O12P2/c7-4-3(1-16-19(10,11)12)18-6(9,5(4)8)2-17-20(13,14)15/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6-/m1/s1;   InChIKey=RNBGYGVWRKECFJ-ARQDHWQXSA-N;   SMILES=O[C@H]1[C@H](O)[C@@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O;   beta-D-Fructose 1,6-bisphosphate
 alt_id: CHEBI:10374;   CHEBI:22767;   CHEBI:41014;   CHEBI:42553
 xref: Beilstein:1690982;   CAS:488-69-7;   DrugBank:DB04551;   KEGG:C05378
 xref_mesh: MESH:C029063
 xref: PDBeChem:FBP;   Reaxys:1690982
 cyclic_relationship: is_conjugate_acid_of CHEBI:32966


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beta-D-fructofuranose 1,6-bisphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of fructose-1,6-diphosphate]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22227475 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22227475 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases degradation
ISO fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
fructose-1,6-diphosphate results in decreased degradation of NOS2 mRNA
CTD PMID:22227475 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            fundamental metabolite 12766
              D-fructose 1,6-bisphosphate 5
                D-fructofuranose 1,6-bisphosphate 5
                  beta-D-fructofuranose 1,6-bisphosphate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      chalcogen 19469
                        oxygen atom 19445
                          oxygen molecular entity 19445
                            hydroxides 19180
                              oxoacid 18498
                                pnictogen oxoacid 10685
                                  phosphorus oxoacid 9666
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8172
                                          phosphate 8172
                                            organic phosphate 8171
                                              carbohydrate phosphate 1734
                                                phospho sugar 1659
                                                  ketose phosphate 8
                                                    ketohexose phosphate 6
                                                      ketohexose bisphosphate 6
                                                        D-fructose 1,6-bisphosphate 5
                                                          D-fructofuranose 1,6-bisphosphate 5
                                                            beta-D-fructofuranose 1,6-bisphosphate 5
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