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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzonitrile
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Accession:CHEBI:27991 term browser browse the term
Definition:A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group.
Synonyms:related_synonym: C6H5-CN;   Cyanobenzene;   Formula=C7H5N;   InChI=1S/C7H5N/c8-6-7-4-2-1-3-5-7/h1-5H;   InChIKey=JFDZBHWFFUWGJE-UHFFFAOYSA-N;   Phenyl cyanide;   SMILES=N#Cc1ccccc1;   benzenenitrile;   benzoic acid nitrile
 alt_id: CHEBI:22725;   CHEBI:3033
 xref: Beilstein:506893;   CAS:100-47-0;   Gmelin:2653;   KEGG:C09814;   MetaCyc:CPD-15582;   PMID:24129580;   UM-BBD_compID:c0367;   Wikipedia:Benzonitrile


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2,6-dichlorobenzonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases metabolic processing ISO CYP2A5 protein results in increased metabolism of dichlobanil CTD PMID:20840855 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO Dexamethasone inhibits the reaction [dichlobanil results in increased expression of IL6 protein] CTD PMID:23921153 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Por cytochrome p450 oxidoreductase decreases response to substance ISO POR protein results in decreased susceptibility to dichlobanil CTD PMID:20840855 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
cyanophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [cyanophos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
perampanel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO CYP1A2 protein results in increased metabolism of perampanel CTD PMID:35200000 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      group 20002
        pseudohalo group 3908
          cyano group 3908
            nitrile 3908
              benzonitrile 5
                2,6-dichlorobenzonitrile 3
                2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 0
                3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile 0
                4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                4-cyanophenol + 1
                benzonitrile oxide 0
                perampanel + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            organic molecule 19835
                              organic cyclic compound 19589
                                carbocyclic compound 18528
                                  benzenoid aromatic compound 17772
                                    benzenes 17582
                                      benzonitrile 5
                                        2,6-dichlorobenzonitrile 3
                                        2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 0
                                        3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile 0
                                        4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                                        4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                                        4-cyanophenol + 1
                                        benzonitrile oxide 0
                                        perampanel + 1
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