CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: benzonitrile
Accession: CHEBI:27991
browse the term
Definition: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group.
Synonyms: related_synonym: C6H5-CN; Cyanobenzene; Formula=C7H5N; InChI=1S/C7H5N/c8-6-7-4-2-1-3-5-7/h1-5H; InChIKey=JFDZBHWFFUWGJE-UHFFFAOYSA-N; Phenyl cyanide; SMILES=N#Cc1ccccc1; benzenenitrile; benzoic acid nitrile
alt_id: CHEBI:22725; CHEBI:3033
xref: Beilstein:506893; CAS:100-47-0; Gmelin:2653; KEGG:C09814; MetaCyc:CPD-15582; PMID:24129580; UM-BBD_compID:c0367; Wikipedia:Benzonitrile
G
Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
increases metabolic processing
ISO
CYP2A5 protein results in increased metabolism of dichlobanil
CTD
PMID:20840855
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
G
Il6
interleukin 6
multiple interactions increases expression
ISO
Dexamethasone inhibits the reaction [dichlobanil results in increased expression of IL6 protein]
CTD
PMID:23921153
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Por
cytochrome p450 oxidoreductase
decreases response to substance
ISO
POR protein results in decreased susceptibility to dichlobanil
CTD
PMID:20840855
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ar
androgen receptor
multiple interactions
ISO
Dihydrotestosterone inhibits the reaction [cyanophos results in increased activity of AR protein]
CTD
PMID:15064155
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases metabolic processing
ISO
CYP1A2 protein results in increased metabolism of perampanel
CTD
PMID:35200000
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
20072
chemical entity
20071
group
20002
pseudohalo group
3908
cyano group
3908
nitrile
3908
benzonitrile
5
2,6-dichlorobenzonitrile
3
2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile
0
3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile
0
4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
0
4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
0
4-cyanophenol +
1
benzonitrile oxide
0
perampanel +
1
Path 2
CHEBI ontology
20072
subatomic particle
20071
composite particle
20071
hadron
20071
baryon
20071
nucleon
20071
atomic nucleus
20071
atom
20071
main group element atom
19971
p-block element atom
19971
carbon group element atom
19894
carbon atom
19887
organic molecular entity
19887
organic molecule
19835
organic cyclic compound
19589
carbocyclic compound
18528
benzenoid aromatic compound
17772
benzenes
17582
benzonitrile
5
2,6-dichlorobenzonitrile
3
2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile
0
3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile
0
4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
0
4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile
0
4-cyanophenol +
1
benzonitrile oxide
0
perampanel +
1