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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzonitrile
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Accession:CHEBI:27991 term browser browse the term
Definition:A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group.
Synonyms:related_synonym: C6H5-CN;   Cyanobenzene;   Formula=C7H5N;   InChI=1S/C7H5N/c8-6-7-4-2-1-3-5-7/h1-5H;   InChIKey=JFDZBHWFFUWGJE-UHFFFAOYSA-N;   Phenyl cyanide;   SMILES=N#Cc1ccccc1;   benzenenitrile;   benzoic acid nitrile
 alt_id: CHEBI:22725;   CHEBI:3033
 xref: Beilstein:506893;   CAS:100-47-0;   Gmelin:2653;   KEGG:C09814;   MetaCyc:CPD-15582;   PMID:24129580;   UM-BBD_compID:c0367;   Wikipedia:Benzonitrile

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2,6-dichlorobenzonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases metabolic processing ISO CYP2A5 protein results in increased metabolism of dichlobanil CTD PMID:20840855 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO Dexamethasone inhibits the reaction [dichlobanil results in increased expression of IL6 protein] CTD PMID:23921153 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Por cytochrome p450 oxidoreductase decreases response to substance ISO POR protein results in decreased susceptibility to dichlobanil CTD PMID:20840855 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
cyanophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [cyanophos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      group 19689
        pseudohalo group 2943
          cyano group 2943
            nitrile 2943
              benzonitrile 4
                2,6-dichlorobenzonitrile 3
                2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 0
                3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile 0
                4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                4-cyanophenol + 1
                benzonitrile oxide 0
                perampanel + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic molecule 19497
                              organic cyclic compound 19321
                                carbocyclic compound 18297
                                  benzenoid aromatic compound 17402
                                    benzenes 17174
                                      benzonitrile 4
                                        2,6-dichlorobenzonitrile 3
                                        2-(\{8-[(3R)-3-aminopiperidin-1-yl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl\}methyl)benzonitrile 0
                                        3-(\{(5R)-3-[3-(1H-imidazol-1-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl\}methyl)benzonitrile 0
                                        4-[(1S,2R)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                                        4-[(1S,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile 0
                                        4-cyanophenol + 1
                                        benzonitrile oxide 0
                                        perampanel + 0
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