Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:27983 term browser browse the term
Definition:A member of the class of aminopyrimidines that is 4,6-diaminopyrimidine bearing an additional formamido substituent at position 5. A DNA lesion formed when DNA exposed to ionising radiation.
Synonyms:exact_synonym: N-(4,6-diaminopyrimidin-5-yl)formamide
 related_synonym: 4,6-Diamino-5-(formylamino)pyrimidine;   4,6-Diamino-5-N-formamidopyrimidine;   4,6-Diamino-5-pyrimidinylformamide;   FAPY;   FAPy-adenine;   Fapyade;   Formula=C5H7N5O;   InChI=1S/C5H7N5O/c6-4-3(10-2-11)5(7)9-1-8-4/h1-2H,(H,10,11)(H4,6,7,8,9);   InChIKey=MVYUVUOSXNYQLL-UHFFFAOYSA-N;   SMILES=Nc1ncnc(N)c1NC=O
 alt_id: CHEBI:1754;   CHEBI:20278;   CHEBI:83705
 xref: CAS:5122-36-1 "ChemIDplus";   HMDB:HMDB0004816;   KEGG:C06502
 xref_mesh: MESH:C039544
 xref: PMID:23685671 "Europe PMC";   Reaxys:149617 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
4,6-diamino-5-formamidopyrimidine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neil1 nei-like DNA glycosylase 1 JBrowse link 8 61,817,258 61,824,023 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        refrigerant 17093
          ammonia 16691
            organic amino compound 16690
              aromatic amine 13592
                aminopyrimidine 1051
                  4,6-diamino-5-formamidopyrimidine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                formamides 1347
                                                  formamidopyrimidine 3
                                                    4,6-diamino-5-formamidopyrimidine 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.