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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cocaine
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Accession:CHEBI:27958 term browser browse the term
Definition:A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Synonyms:exact_synonym: (1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate;   methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
 related_synonym: 2-methyl-3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester);   Benzoylmethylecgonine;   Cocain;   Cocaina;   Formula=C17H21NO4;   InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1;   InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N;   Kokain;   Neurocaine;   SMILES=[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C;   [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester;   beta-Cocain;   cocainum;   l-Cocain;   l-cocaine;   methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate;   methyl benzoylecgonine
 alt_id: CHEBI:23346;   CHEBI:3801;   CHEBI:41642
 xref: Beilstein:3621912;   Beilstein:5291037;   Beilstein:91034;   CAS:50-36-2;   DrugBank:DB00907;   Drug_Central:723;   Gmelin:170209;   KEGG:C01416;   KEGG:D00110;   KNApSAcK:C00002285
 xref_mesh: MESH:D003042
 xref: MetaCyc:CPD-9776;   PDBeChem:COC;   PMID:11416615;   PMID:11853120;   PMID:14962054;   PMID:17551070;   PMID:19536276;   PMID:21150772;   PMID:25303034;   Reaxys:5291037;   Reaxys:91034;   Wikipedia:Cocaine
 cyclic_relationship: is_conjugate_base_of CHEBI:60056


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cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase affects expression EXP Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr12:31,113,098...31,156,411 JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 2:144,163,436...144,186,086 JBrowse link
G Aanat aralkylamine N-acetyltransferase affects response to substance ISO AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr10:101,827,072...101,831,805 JBrowse link
G Abat 4-aminobutyrate aminotransferase increases response to substance ISO ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr10:6,996,688...7,092,835 JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 decreases expression EXP Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 2:210,164,813...210,302,069 JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr10:95,240,159...95,309,195 JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr10:79,296,681...79,342,749 JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 affects expression EXP Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr11:80,473,809...80,567,257 JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr 4:175,531,854...175,655,849 JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 affects expression EXP Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr 6:104,246,459...104,260,965 JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression ISO Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 6:25,422,526...25,427,514 JBrowse link
G Abhd14a abhydrolase domain containing 14A affects expression EXP Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 8:107,079,139...107,089,004 JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr 7:9,124,332...9,132,762 JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase affects expression ISO Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 3:14,979,853...15,083,065 JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 8:118,872,996...118,881,852 JBrowse link
G Acan aggrecan affects expression EXP Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr 1:132,981,034...133,044,416 JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr10:90,910,316...90,930,437 JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression ISO Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr15:28,102,112...28,147,001 JBrowse link
G Ackr2 atypical chemokine receptor 2 affects expression EXP Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 8:121,559,563...121,573,633 JBrowse link
G Aco2 aconitase 2 increases expression ISO Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr 7:113,385,677...113,428,794 JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr 1:254,289,513...254,336,608 JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression EXP Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr 3:139,450,383...139,500,325 JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 4:116,021,832...116,046,475 JBrowse link
G Actn2 actinin alpha 2 increases expression ISO Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr17:58,143,334...58,210,622 JBrowse link
G Acvr1c activin A receptor type 1C increases expression EXP Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 3:42,815,490...42,892,423 JBrowse link
G Acy3 aminoacylase 3 affects expression EXP Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr 1:201,279,751...201,285,803 JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression EXP Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr10:30,491,362...30,583,115 JBrowse link
G Adam1a ADAM metallopeptidase domain 1a multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr12:35,017,433...35,020,300 JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 decreases expression EXP Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr18:52,346,448...52,531,245 JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression EXP Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr 1:7,954,520...7,975,254 JBrowse link
G Adcy2 adenylate cyclase 2 affects expression EXP Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr 1:34,375,639...34,822,237 JBrowse link
G Adcy8 adenylate cyclase 8 affects expression EXP Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr 7:96,417,310...96,665,911 JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1 mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]
CTD PMID:29673861 NCBI chr 9:113,102,632...113,122,500 JBrowse link
G Adcyap1r1 ADCYAP receptor type I increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1R1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]
CTD PMID:29673861 NCBI chr 4:84,593,558...84,642,700 JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr 1:194,629,744...194,673,254 JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 affects expression EXP Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr 9:2,242,476...2,398,000 JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression EXP Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr 9:17,661,258...17,696,359 JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr19:24,202,405...24,244,137 JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 affects expression EXP Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr14:26,336,320...27,104,060 JBrowse link
G Adora1 adenosine A1 receptor affects expression
affects response to substance
EXP
ISO
Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine
CTD PMID:12358776 PMID:19092996 NCBI chr13:45,658,872...45,695,821 JBrowse link
G Adora2a adenosine A2a receptor increases response to substance
increases expression
ISO ADORA2A results in increased susceptibility to Cocaine
Cocaine deficiency results in increased expression of ADORA2A mRNA
CTD PMID:16123743 PMID:27126842 NCBI chr20:13,315,848...13,333,386 JBrowse link
G Adora2b adenosine A2B receptor affects expression EXP Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr10:46,940,394...46,956,772 JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr10:28,255,025...28,373,418 JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029 PMID:18596687 NCBI chr 1:255,772,217...255,773,617 JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression EXP Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr10:37,498,825...37,579,751 JBrowse link
G Afmid arylformamidase increases expression EXP Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr10:103,046,129...103,061,718 JBrowse link
G Afp alpha-fetoprotein increases expression EXP Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr14:17,573,412...17,591,476 JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression EXP Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr 7:62,897,282...62,914,295 JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions
affects response to substance
ISO AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine
CTD PMID:20643829 NCBI chr 7:105,018,202...105,105,120 JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 3:15,229,476...15,254,033 JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects expression
increases expression
ISO Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA
CTD PMID:15681117 PMID:18000554 NCBI chr  X:127,650,223...127,689,356 JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 affects expression ISO Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr20:29,654,283...29,679,239 JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Ak3 adenylate kinase 3 affects expression EXP Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr 1:226,737,472...226,764,647 JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 4:66,154,246...66,187,505 JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 affects expression EXP Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr17:65,735,909...65,750,441 JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Cocaine affects the expression of AKR7A3 mRNA CTD PMID:20187946 NCBI chr 5:151,590,968...151,601,394 JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects expression
multiple interactions
increases phosphorylation
EXP
ISO
Cocaine affects the expression of AKT1 mRNA
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein
Cocaine results in increased phosphorylation of AKT1 protein
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]
CTD PMID:18702665 PMID:20187946 PMID:25933444 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression EXP Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr11:48,336,123...48,536,296 JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 decreases expression EXP Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr 3:77,700,936...77,890,221 JBrowse link
G Amh anti-Mullerian hormone increases expression EXP Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr 7:8,906,776...8,909,184 JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 affects expression EXP Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 2:195,823,138...195,828,593 JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 8:108,741,899...108,743,425 JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog decreases expression EXP Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr 4:182,155,140...182,182,085 JBrowse link
G Ankrd54 ankyrin repeat domain 54 affects expression EXP Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr 7:110,614,942...110,627,739 JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression EXP Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr 7:24,313,810...25,479,307 JBrowse link
G Anxa7 annexin A7 affects expression EXP Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr15:3,821,798...3,849,659 JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 2:216,276,631...216,309,020 JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr10:68,099,397...68,205,023 JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr11:80,355,307...80,364,218 JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 decreases expression ISO Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr 1:77,417,496...77,428,903 JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 affects expression EXP Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr15:22,355,478...22,385,222 JBrowse link
G Apcs amyloid P component, serum increases expression ISO Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr13:85,373,338...85,374,134 JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit affects expression EXP Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 2:183,437,676...183,443,113 JBrowse link
G Aplnr apelin receptor increases expression EXP Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr 3:70,217,407...70,221,052 JBrowse link
G Apol11a apolipoprotein L 11a decreases expression EXP Cocaine results in decreased expression of APOL11A mRNA CTD PMID:27899881 NCBI chr 7:109,248,260...109,262,266 JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO Cocaine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632 JBrowse link
G Apold1 apolipoprotein L domain containing 1 affects expression EXP Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr 4:167,768,437...167,825,706 JBrowse link
G Apoo apolipoprotein O increases expression EXP Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:59,157,971...59,262,940 JBrowse link
G App amyloid beta precursor protein decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA
CTD PMID:15009677 PMID:16710320 PMID:17898221 NCBI chr11:24,019,774...24,236,584 JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 increases expression EXP Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr16:2,118,503...2,166,741 JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression
increases expression
multiple interactions
EXP Cocaine affects the expression of ARC mRNA
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
CTD PMID:7722525 PMID:12117546 PMID:15254092 PMID:17851536 PMID:18311559 PMID:18361437 PMID:20187946 PMID:24810662 NCBI chr 7:106,555,968...106,559,697 JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr16:1,896,692...1,913,267 JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr 3:77,621,377...77,643,400 JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 2:210,060,036...210,132,572 JBrowse link
G Arhgap30 Rho GTPase activating protein 30 increases expression EXP Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr13:83,822,290...83,843,634 JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression EXP Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr10:49,655,583...49,822,876 JBrowse link
G Arhgap5 Rho GTPase activating protein 5 increases expression EXP Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr 6:69,975,904...70,039,299 JBrowse link
G Arhgap9 Rho GTPase activating protein 9 decreases expression EXP Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr 7:63,148,573...63,157,025 JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 affects expression EXP Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr 1:80,499,026...80,520,954 JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 affects expression EXP Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr16:77,671,021...77,782,593 JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 affects expression EXP Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:97,929,032...97,932,032 JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Cocaine results in decreased expression of ARNTL mRNA CTD PMID:15994025 NCBI chr 1:167,331,756...167,430,235 JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression EXP Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr12:9,502,496...9,525,304 JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions EXP Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr 8:75,779,640...75,802,474 JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions
increases expression
EXP
ISO
Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein]
Cocaine deficiency results in increased expression of ARPP21 mRNA
CTD PMID:11268215 PMID:27126842 NCBI chr 8:112,034,636...112,199,273 JBrowse link
G Art5 ADP-ribosyltransferase 5 increases expression EXP Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr 1:156,473,362...156,483,324 JBrowse link
G As3mt arsenite methyltransferase affects expression EXP Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr 1:245,595,939...245,628,921 JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression EXP Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr 7:95,786,130...96,093,111 JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression EXP Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr 1:230,544,227...230,610,524 JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression EXP Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr10:65,070,682...65,118,489 JBrowse link
G Ate1 arginyltransferase 1 increases expression EXP Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr 1:184,961,548...185,081,112 JBrowse link
G Atf3 activating transcription factor 3 increases expression
decreases expression
EXP Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA
CTD PMID:23644055 PMID:27899881 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 PMID:23644055 NCBI chr 7:111,804,135...111,806,457 JBrowse link
G Atf6 activating transcription factor 6 affects expression EXP Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr13:82,927,579...83,106,381 JBrowse link
G Atf7 activating transcription factor 7 affects expression ISO Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr 7:133,660,491...133,750,902 JBrowse link
G Atg2b autophagy related 2B affects expression EXP Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr 6:124,522,283...124,592,412 JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase affects expression EXP Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 9:94,282,417...94,314,109 JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr 8:53,828,741...53,932,773 JBrowse link
G Atp10a ATPase phospholipid transporting 10A (putative) decreases expression EXP Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221 PMID:27899881 NCBI chr 1:109,556,760...109,730,440 JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression ISO Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 2:189,020,722...189,048,826 JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression
affects expression
EXP Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA
CTD PMID:16076954 PMID:20187946 NCBI chr 1:80,572,790...80,601,936 JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression EXP Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr10:54,318,698...54,324,933 JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]
CTD PMID:18355967 NCBI chr 8:96,910,265...96,941,592 JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects expression ISO Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:71,292,406...71,300,342 JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr 7:515,454...521,858 JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr 3:163,259,072...163,261,974 JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA
CTD PMID:12629581 PMID:20187946 NCBI chr 3:58,810,535...58,813,185 JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression EXP Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 2:193,424,138...193,435,418 JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d affects expression EXP Cocaine affects the expression of ATP5H mRNA CTD PMID:12358776 NCBI chr10:100,657,700...100,662,960 JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D affects expression EXP Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr 6:97,656,725...97,672,211 JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]
CTD PMID:18355967 NCBI chr 2:175,378,514...175,402,265 JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) affects response to substance ISO ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:74,176,863...74,368,993 JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 5:129,265,789...129,293,556 JBrowse link
G Atrx ATRX, chromatin remodeler increases expression EXP Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:70,850,981...70,997,330 JBrowse link
G Atxn1 ataxin 1 affects expression EXP Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr17:18,737,491...19,142,360 JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr 6:121,072,228...121,107,902 JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression EXP Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr12:16,930,990...16,939,333 JBrowse link
G Baalc BAALC binder of MAP3K1 and KLF4 decreases expression ISO Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr 7:69,918,998...69,992,289 JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr11:26,939,429...26,974,876 JBrowse link
G Bach2 BTB domain and CNC homolog 2 affects expression ISO Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 5:46,632,338...46,982,676 JBrowse link
G Bad BCL2-associated agonist of cell death affects expression ISO Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr 1:204,133,502...204,142,829 JBrowse link
G Bag1 BAG cochaperone 1 affects expression ISO Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 5:56,068,494...56,081,075 JBrowse link
G Bag3 BAG cochaperone 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA
CTD PMID:15681117 PMID:27899881 NCBI chr 1:183,103,038...183,126,862 JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr17:54,121,251...54,125,816 JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 affects expression EXP Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr 2:75,816,130...75,863,801 JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of BAX mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]
Cocaine results in increased activity of BAX protein
Cocaine affects the expression of BAX mRNA
CTD PMID:11392460 PMID:15681117 PMID:15685203 PMID:17084983 PMID:17635674 PMID:18974856 PMID:20948987 PMID:29673861 PMID:30393195 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions
increases expression
ISO [SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
Cocaine results in increased expression of BAZ1B mRNA
CTD PMID:27053203 NCBI chr12:21,431,985...21,489,956 JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression EXP Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 3:44,384,282...44,681,619 JBrowse link
G Bcap31 B-cell receptor-associated protein 31 affects expression EXP Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:151,397,567...151,429,666 JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression EXP Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr 4:177,964,834...178,046,573 JBrowse link
G Bche butyrylcholinesterase affects metabolic processing
multiple interactions
increases hydrolysis
increases metabolic processing
decreases response to substance
affects hydrolysis
decreases metabolic processing
affects degradation
ISO BCHE protein affects the metabolism of Cocaine
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine
CTD PMID:572161 PMID:16275916 PMID:17989928 PMID:18514178 PMID:18514640 PMID:19067679 PMID:20060817 PMID:20219449 PMID:20971807 PMID:22917637 PMID:22960160 PMID:24582612 PMID:25814464 PMID:27154495 PMID:30080993 NCBI chr 2:158,308,674...158,401,148 JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B increases expression ISO Cocaine deficiency results in increased expression of BCL11B mRNA CTD PMID:27126842 NCBI chr 6:126,834,531...126,927,720 JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
multiple interactions
decreases expression
increases phosphorylation
increases expression
ISO
EXP
Cocaine affects the expression of BCL2 mRNA
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]
Cocaine results in increased phosphorylation of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
Cocaine results in increased expression of BCL2 protein
CTD PMID:11392460 PMID:15365088 PMID:15681117 PMID:15685203 PMID:17084983 PMID:18974856 PMID:19183502 PMID:19879923 PMID:29673861 PMID:30393195 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
EXP
ISO
Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
Cocaine results in decreased expression of BCL2L1 protein
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]
CTD PMID:16076954 PMID:29673861 PMID:30393195 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Bcl2l11 BCL2 like 11 increases expression EXP Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 3:115,366,783...115,404,068 JBrowse link
G Bdnf brain-derived neurotrophic factor decreases response to substance
increases expression
decreases activity
affects expression
multiple interactions
decreases expression
increases response to substance
ISO
EXP
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of BDNF mRNA
Cocaine results in decreased activity of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
BDNF results in increased susceptibility to Cocaine
CTD PMID:12099907 PMID:14973246 PMID:16423334 PMID:17194538 PMID:17618281 PMID:18311559 PMID:18355967 PMID:19321768 PMID:20554863 PMID:20711185 PMID:20810894 PMID:20826313 PMID:24358339 PMID:26558777 NCBI chr 3:96,165,042...96,215,621 JBrowse link
G Begain brain-enriched guanylate kinase-associated affects expression EXP Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr 6:127,943,651...127,979,876 JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression EXP Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 2:100,486,400...100,489,510 JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression EXP Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 4:141,618,453...141,624,154 JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr 4:154,113,198...154,136,353 JBrowse link
G Bik BCL2-interacting killer affects expression ISO Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr 7:114,672,277...114,691,296 JBrowse link
G Bmp2k BMP-2 inducible kinase affects expression EXP Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr14:12,481,194...12,579,411 JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression EXP Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 9:61,192,718...61,307,280 JBrowse link
G Bnip2 BCL2 interacting protein 2 affects expression ISO Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr 8:70,640,436...70,661,782 JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression ISO Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr 1:193,708,164...193,725,348 JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects expression ISO Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr15:41,174,594...41,197,730 JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression
ISO
EXP
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein
CTD PMID:26558777 NCBI chr 7:11,216,446...11,296,029 JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin affects expression EXP Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr 1:205,731,814...205,743,430 JBrowse link
G Bst1 bone marrow stromal cell antigen 1 affects expression EXP Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr14:67,253,706...67,270,203 JBrowse link
G Btbd9 BTB domain containing 9 increases expression EXP Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr20:8,286,337...8,645,567 JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression EXP Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr13:45,531,881...45,535,642 JBrowse link
G Btk Bruton tyrosine kinase decreases expression EXP Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:97,722,796...97,762,315 JBrowse link
G C1qbp complement C1q binding protein decreases expression EXP Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr10:55,699,954...55,704,605 JBrowse link
G C1qtnf1 C1q and TNF related 1 affects expression EXP Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr10:103,660,319...103,681,662 JBrowse link
G C1qtnf4 C1q and TNF related 4 decreases expression EXP Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr 3:76,854,368...76,872,991 JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator decreases expression EXP Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr 1:154,715,151...154,812,955 JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression EXP Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 2:181,997,393...182,001,938 JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression EXP Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr10:69,827,945...69,836,501 JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr15:33,606,588...33,710,518 JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects response to substance ISO CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr16:5,227,157...5,521,163 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects expression EXP Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr 7:129,784,799...129,797,074 JBrowse link
G Cald1 caldesmon 1 affects expression EXP Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 4:63,265,781...63,446,936 JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759 JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284 JBrowse link
G Calr calreticulin decreases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in decreased expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]
Cocaine affects the expression of CALR mRNA
CTD PMID:18355967 PMID:20187946 NCBI chr19:23,308,525...23,313,420 JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr 1:194,862,671...194,873,861 JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr13:104,877,909...104,901,658 JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression
ISO
EXP
CAMK2A affects the susceptibility to Cocaine
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
CTD PMID:14725635 PMID:17609678 PMID:19217379 PMID:28194001 NCBI chr18:54,378,642...54,441,120 JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA
CTD PMID:17205118 PMID:20187946 NCBI chr14:80,845,206...80,934,172 JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases response to substance
decreases response to substance
ISO CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine
CTD PMID:19001277 NCBI chr18:24,582,988...24,811,918 JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects expression EXP Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr17:18,054,234...18,203,453 JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression ISO Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 5:151,435,600...151,535,409 JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression EXP Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr12:13,620,979...13,758,115 JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 affects expression EXP Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr 8:20,097,262...20,141,950 JBrowse link
G Carnmt1 carnosine N-methyltransferase 1 affects expression EXP Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr 1:216,093,720...216,123,360 JBrowse link
G Cartpt CART prepropeptide increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA
CTD PMID:15009677 PMID:17851536 PMID:20187946 NCBI chr 2:31,255,098...31,257,452 JBrowse link
G Casp2 caspase 2 increases activity
increases expression
EXP Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA
CTD PMID:16076954 PMID:16638611 NCBI chr 4:71,149,632...71,167,388 JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of CASP3 protein
Cocaine results in increased cleavage of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]
Cocaine results in increased activity of CASP3 protein
Cocaine affects the expression of CASP3 protein
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 mRNA
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:14741756 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 PMID:19183502 PMID:20600547 PMID:29673861 PMID:30393195 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp4 caspase 4 affects expression
decreases expression
ISO Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA
CTD PMID:12629581 PMID:15681117 NCBI chr 8:2,599,017...2,635,097 JBrowse link
G Casp8 caspase 8 affects expression
increases activity
ISO
EXP
Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein
CTD PMID:11392460 PMID:15681117 PMID:18974856 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Casp9 caspase 9 affects expression
increases activity
multiple interactions
increases expression
ISO
EXP
Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased activity of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]
Cocaine affects the expression of CASP9 protein
Cocaine results in increased expression of CASP9 protein
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression EXP Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr14:79,086,136...79,090,549 JBrowse link
G Cat catalase decreases activity
increases activity
increases expression
ISO
EXP
Cocaine results in decreased activity of CAT protein
Cocaine results in increased activity of CAT protein
Cocaine results in increased expression of CAT protein
CTD PMID:14576513 PMID:16085363 PMID:29475069 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Catsper2 cation channel, sperm associated 2 increases expression EXP Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr 3:108,368,654...108,389,380 JBrowse link
G Cbln1 cerebellin 1 precursor multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr19:19,608,763...19,612,572 JBrowse link
G Ccdc127 coiled-coil domain containing 127 increases expression EXP Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr 1:28,928,420...28,935,885 JBrowse link
G Ccdc174 coiled-coil domain containing 174 affects expression EXP Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 4:124,392,183...124,419,035 JBrowse link
G Ccdc73 coiled-coil domain containing 73 decreases expression EXP Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr 3:91,282,919...91,424,269 JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression EXP Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr14:103,104,091...103,256,112 JBrowse link
G Ccdc93 coiled-coil domain containing 93 increases expression EXP Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr13:32,607,618...32,675,993 JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
increases response to substance
ISO Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine
CTD PMID:11403953 PMID:18000554 NCBI chr 1:159,771,733...159,781,738 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
multiple interactions
ISO
EXP
Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]
CTD PMID:10065903 PMID:20354174 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr 1:20,802,199...20,805,315 JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr 7:86,094,000...86,101,022 JBrowse link
G Ccna2 cyclin A2 decreases expression ISO
EXP
Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 2:119,427,239...119,433,645 JBrowse link
G Ccnd1 cyclin D1 affects expression EXP Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr 9:13,394,161...13,400,341 JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 2:150,184,865...150,199,524 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 affects expression
increases response to substance
EXP
ISO
Cocaine affects the expression of CCR2 mRNA
CCR2 results in increased susceptibility to Cocaine
CTD PMID:20187946 PMID:20354174 NCBI chr 8:123,734,465...123,742,483 JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 8:123,752,423...123,757,538 JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 affects response to substance ISO CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 4:90,153,873...91,391,441 JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression EXP Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr 7:52,692,725...52,705,478 JBrowse link
G Cd180 CD180 molecule decreases expression EXP Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr 2:33,855,940...33,870,046 JBrowse link
G Cd276 Cd276 molecule affects expression EXP Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr 8:58,937,751...58,968,082 JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr 3:89,155,850...89,244,615 JBrowse link
G Cd47 Cd47 molecule affects expression EXP Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr11:50,906,052...50,970,000 JBrowse link
G Cd74 CD74 molecule affects expression EXP Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr18:54,256,757...54,266,003 JBrowse link
G Cd81 Cd81 molecule increases response to substance
increases expression
affects response to substance
ISO
EXP
CD81 protein results in increased susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA
CD81 protein affects the susceptibility to Cocaine
CTD PMID:11178868 PMID:12113778 PMID:15715673 NCBI chr 1:198,235,861...198,251,660 JBrowse link
G Cd93 CD93 molecule decreases expression EXP Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr 3:135,891,859...135,898,378 JBrowse link
G Cdc14b cell division cycle 14B decreases expression EXP Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr17:844,731...934,787 JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 8:109,864,356...109,882,734 JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Cdh16 cadherin 16 affects expression EXP Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr19:360,824...371,008 JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 5:25,262,820...25,314,884 JBrowse link
G Cdk18 cyclin-dependent kinase 18 affects expression EXP Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr13:43,555,597...43,582,210 JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr 7:62,885,647...62,889,562 JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein
CTD PMID:11268215 PMID:12787079 PMID:16263094 PMID:17339080 PMID:17680995 PMID:20187946 NCBI chr 4:10,754,682...10,760,110 JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions
increases expression
decreases expression
ISO
EXP
CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein
Cocaine results in decreased expression of CDK5R1 protein
CTD PMID:11268215 PMID:15665076 PMID:16263094 NCBI chr10:65,484,266...65,485,467 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cel carboxyl ester lipase increases expression EXP Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 3:11,883,532...11,891,035 JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
affects binding
ISO CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
CES1 protein results in increased hydrolysis of Cocaine
Cocaine binds to CES1 protein
CTD PMID:8930175 PMID:9311626 PMID:12679808 PMID:12773168 PMID:25445008 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
increases hydrolysis
ISO Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
Cocaine results in decreased expression of CES2 mRNA
CES2 protein results in increased hydrolysis of Cocaine
CTD PMID:8930175 PMID:9169443 PMID:12629581 NCBI chr19:32,974,242...32,988,842 JBrowse link
G Cfh complement factor H decreases expression EXP Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr13:51,512,376...51,613,829 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 9:60,185,338...60,236,173 JBrowse link
G Chfr checkpoint with forkhead and ring finger domains affects expression EXP Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr12:46,504,497...46,538,104 JBrowse link
G Chn1 chimerin 1 affects expression EXP Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 3:58,509,822...58,676,774 JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects expression EXP Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr 3:77,893,425...77,901,166 JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance EXP CHRM5 mutant form results in decreased susceptibility to Cocaine CTD PMID:20393457 NCBI chr 3:99,284,846...99,337,252 JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 8:55,401,981...55,415,012 JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 3:168,136,246...168,157,839 JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit decreases response to substance ISO CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr 8:55,369,794...55,398,526 JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
increases response to substance
EXP
ISO
Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine
CTD PMID:10336510 PMID:11282258 NCBI chr 2:175,181,402...175,189,619 JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr10:55,331,211...55,339,923 JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression EXP Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr19:34,782,005...34,792,306 JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 6:95,464,488...95,485,208 JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects expression EXP Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 3:114,458,671...114,465,928 JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression ISO Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:60,894,917...60,920,485 JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression ISO Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr15:29,252,203...29,256,759 JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression EXP Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr20:17,255,302...17,268,688 JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 2:223,828,937...223,853,768 JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 5:134,246,936...134,247,827 JBrowse link
G Ckb creatine kinase B multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 6:130,729,420...130,732,301 JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 1:79,061,390...79,071,721 JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects expression EXP Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr 3:108,329,859...108,335,760 JBrowse link
G Clcn7 chloride voltage-gated channel 7 affects expression EXP Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr10:14,151,758...14,177,130 JBrowse link
G Cldn11 claudin 11 decreases expression ISO Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 2:112,207,745...112,221,050 JBrowse link
G Clec4f C-type lectin domain family 4, member F affects expression EXP Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 4:116,129,023...116,138,744 JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr20:3,764,867...3,773,711 JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr12:32,910,932...33,017,891 JBrowse link
G Clk1 CDC-like kinase 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]
CTD PMID:18355967 NCBI chr 9:59,947,774...59,959,002 JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr10:35,523,382...35,541,387 JBrowse link
G Clock clock circadian regulator increases expression ISO Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr14:31,908,542...31,992,673 JBrowse link
G Cltb clathrin, light chain B decreases expression ISO Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581 PMID:15009677 NCBI chr17:10,001,512...10,019,201 JBrowse link
G Clybl citramalyl-CoA lyase increases expression EXP Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr15:99,283,644...99,505,697 JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression EXP Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr 3:144,819,166...144,884,825 JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 increases expression ISO Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:36,908,135...37,148,337 JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance
increases activity
decreases response to substance
multiple interactions
ISO CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein
CNR1 mutant form results in decreased susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:9106242 PMID:16314880 PMID:17596442 PMID:19052543 PMID:20554863 NCBI chr 5:48,408,543...48,436,099 JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 5:148,125,222...148,151,548 JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 3:49,753,260...49,915,168 JBrowse link
G Coil coilin affects expression EXP Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr10:73,789,077...73,810,378 JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects expression EXP Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 5:61,501,963...61,607,591 JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr10:79,883,622...79,900,625 JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 9:47,374,611...47,410,547 JBrowse link
G Coq6 coenzyme Q6 monooxygenase affects expression EXP Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr 6:104,007,814...104,019,888 JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr10:10,880,299...10,941,001 JBrowse link
G Cox20 cytochrome c oxidase assembly factor COX20 decreases expression EXP Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr13:90,065,900...90,075,386 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression EXP Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr 8:57,922,374...57,933,781 JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression
increases expression
EXP Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein
CTD PMID:20187946 PMID:25100957 NCBI chr12:41,261,983...41,265,037 JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr 7:67,129,265...67,142,001 JBrowse link
G Cox7b cytochrome c oxidase subunit 7B affects expression EXP Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:71,083,486...71,089,733 JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression EXP Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cplx1 complexin 1 affects expression EXP Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Cpne8 copine 8 increases expression EXP Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr 7:121,615,293...121,789,507 JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression
EXP
ISO
Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased phosphorylation of CREB1 protein
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
Cocaine affects the phosphorylation of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
CTD PMID:12595601 PMID:15470197 PMID:15665076 PMID:16219028 PMID:16339038 PMID:16710312 PMID:18596687 PMID:20187946 PMID:20810894 PMID:24358339 NCBI chr 9:65,903,511...65,972,562 JBrowse link
G Crebbp CREB binding protein increases expression EXP Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr10:11,335,551...11,461,888 JBrowse link
G Crebrf CREB3 regulatory factor increases expression EXP Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr10:16,399,170...16,479,650 JBrowse link
G Crem cAMP responsive element modulator affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA
CTD PMID:18355967 PMID:27899881 NCBI chr17:54,238,889...54,305,989 JBrowse link
G Crh corticotropin releasing hormone multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein
CTD PMID:7796157 PMID:11597771 PMID:12782395 PMID:15930388 PMID:18596687 NCBI chr 2:102,143,055...102,144,919 JBrowse link
G Crhbp corticotropin releasing hormone binding protein increases expression EXP Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr 2:26,692,403...26,704,710 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr10:89,040,203...89,083,481 JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr 6:132,221,120...132,226,066 JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression EXP Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 5:1,267,347...1,314,926 JBrowse link
G Crp C-reactive protein increases expression ISO Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr13:85,131,635...85,175,179 JBrowse link
G Crtac1 cartilage acidic protein 1 affects expression EXP Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr 1:241,091,679...241,233,677 JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 multiple interactions EXP [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr16:18,988,197...19,046,913 JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr 7:18,529,823...18,594,092 JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr 3:78,374,995...78,405,001 JBrowse link
G Cryab crystallin, alpha B decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA
CTD PMID:15009677 PMID:27899881 NCBI chr 8:51,093,441...51,099,161 JBrowse link
G Crybb2 crystallin, beta B2 decreases expression ISO Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr12:43,569,747...43,579,671 JBrowse link
G Csad cysteine sulfinic acid decarboxylase affects expression
decreases expression
EXP Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein
CTD PMID:20187946 PMID:25100957 NCBI chr 7:133,308,571...133,337,914 JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha decreases expression EXP Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr14:98,089...103,261 JBrowse link
G Csn3 casein kappa affects expression EXP Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr14:20,154,032...20,160,585 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr 3:140,709,984...140,756,757 JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 affects expression EXP Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 8:110,220,653...110,234,750 JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr 7:46,349,109...46,367,743 JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 affects expression EXP Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr10:54,704,367...54,713,781 JBrowse link
G Ctnnb1 catenin beta 1 affects expression
multiple interactions
EXP Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]
CTD PMID:20187946 PMID:27422367 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 5:159,961,961...160,010,942 JBrowse link
G Ctnnd2 catenin delta 2 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 2:81,168,976...82,016,495 JBrowse link
G Ctrl chymotrypsin-like affects expression
increases expression
EXP Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr19:33,827,279...33,829,129 JBrowse link
G Ctsb cathepsin B affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]
CTD PMID:15681117 PMID:18355967 NCBI chr15:37,389,636...37,410,508 JBrowse link
G Ctsd cathepsin D affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein
CTD PMID:15681117 PMID:25100957 NCBI chr 1:197,527,467...197,539,343 JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr10:72,892,637...72,986,546 JBrowse link
G Cul4b cullin 4B increases expression ISO Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:117,287,481...117,326,688 JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 increases expression EXP Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr 6:290,148...356,636 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr19:10,227,337...10,237,826 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion ISO Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr14:15,704,772...15,706,969 JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr14:15,722,868...15,727,779 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr13:40,077,976...40,081,883 JBrowse link
G Cxxc5 CXXC finger protein 5 affects expression EXP Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr18:27,427,591...27,458,579 JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr19:50,487,598...50,495,669 JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
increases response to substance
ISO Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine
CTD PMID:18952886 NCBI chr  X:13,360,583...13,392,517 JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr 7:108,067,106...108,069,483 JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects expression
EXP
ISO
Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]
Cocaine affects the expression of CYCS mRNA
CTD PMID:15681117 PMID:21424555 NCBI chr 4:79,651,894...79,653,994 JBrowse link
G Cygb cytoglobin decreases expression EXP Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr10:101,877,675...101,887,442 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression EXP Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr 8:54,553,165...54,580,758 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression EXP Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr 1:235,471,368...235,475,204 JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases response to substance EXP CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 4:117,041,808...117,058,628 JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 decreases expression EXP Cocaine results in decreased expression of CYP2J10 mRNA CTD PMID:27899881 NCBI chr 5:110,960,319...110,995,220 JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
multiple interactions
ISO Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]
CTD PMID:11856816 NCBI chr 5:111,179,981...111,207,490 JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Cocaine affects the expression of CYP3A23-3A1 mRNA CTD PMID:20187946 NCBI chr12:9,256,159...9,285,020 JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 4:30,036,956...30,055,410 JBrowse link
G Cyss cystatin S affects expression EXP Cocaine affects the expression of CYSS mRNA CTD PMID:20187946 NCBI chr 3:137,432,272...137,436,610 JBrowse link
G Dab2ip DAB2 interacting protein decreases expression EXP Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 3:18,915,290...19,086,282 JBrowse link
G Dazap1 DAZ associated protein 1 affects expression EXP Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr 7:9,423,673...9,448,116 JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance
decreases response to substance
ISO DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine
CTD PMID:10673769 PMID:12555232 PMID:18083142 NCBI chr 3:10,488,260...10,505,245 JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr17:9,150,608...9,164,982 JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr13:84,609,838...84,667,025 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA
CTD PMID:15681117 PMID:20187946 PMID:23644055 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr13:82,193,623...82,318,229 JBrowse link
G Ddx41 DEAD-box helicase 41 decreases expression ISO Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr17:9,102,926...9,108,415 JBrowse link
G Ddx50 DExD-box helicase 50 affects expression EXP Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr20:30,561,623...30,591,324 JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression EXP Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr 8:44,931,127...44,967,773 JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 1:196,401,857...196,435,541 JBrowse link
G Dhh desert hedgehog signaling molecule affects expression EXP Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr 7:130,050,910...130,056,406 JBrowse link
G Dhx30 DExH-box helicase 30 affects expression EXP Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 8:110,064,751...110,096,954 JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression EXP Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 3:9,455,914...9,464,169 JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression EXP Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr 1:144,451,653...146,503,949 JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression
increases expression
multiple interactions
decreases response to substance
decreases expression
EXP
ISO
Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in increased expression of DLG4 protein
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]
DLG4 protein results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of DLG4 mRNA
CTD PMID:14980210 PMID:19629758 PMID:20187946 PMID:20534846 PMID:20600170 NCBI chr10:54,740,700...54,769,097 JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]
CTD PMID:18355967 NCBI chr 9:14,677,102...14,681,515 JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 affects response to substance ISO DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr20:8,692,939...8,946,780 JBrowse link
G Dnm1 dynamin 1 affects expression EXP Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 3:15,604,782...15,648,654 JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation
EXP
ISO
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein
CTD PMID:30158054 PMID:31494168 NCBI chr11:84,581,216...84,632,382 JBrowse link
G Dnm2 dynamin 2 affects expression EXP Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr 8:19,978,313...20,060,162 JBrowse link
G Dnm3 dynamin 3 affects expression EXP Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr13:74,359,043...74,838,135 JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr 1:242,736,189...242,829,498 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]
CTD PMID:22438930 NCBI chr 3:142,130,592...142,169,124 JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 9:14,481,296...14,484,034 JBrowse link
G Dpf2 double PHD fingers 2 increases expression ISO Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr 1:203,183,674...203,199,037 JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions EXP [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr15:41,005,551...41,111,724 JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression EXP Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr18:35,374,429...35,480,462 JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
increases expression
decreases expression
affects response to substance
affects expression
increases response to substance
decreases response to substance
ISO
EXP
1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
Cocaine deficiency results in increased expression of DRD1 mRNA
Cocaine results in decreased expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 results in increased susceptibility to Cocaine
DRD1 gene mutant form results in decreased susceptibility to Cocaine
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]
CTD PMID:2213551 PMID:8001143 PMID:11421588 PMID:11602327 PMID:15049517 PMID:15056714 PMID:16674926 PMID:17161392 PMID:20435100 PMID:20456009 PMID:20956312 PMID:27126842 PMID:27129946 NCBI chr17:10,540,440...10,544,971 JBrowse link
G Drd2 dopamine receptor D2 decreases expression
increases expression
affects response to substance
increases activity
multiple interactions
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
Cocaine deficiency results in increased expression of DRD2 mRNA
DRD2 protein affects the susceptibility to Cocaine
Cocaine results in increased activity of DRD2 protein
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
DRD2 protein results in decreased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 results in increased susceptibility to Cocaine
DRD2 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the reaction [Raclopride binds to DRD2]
CTD PMID:2213551 PMID:9892293 PMID:11126397 PMID:11602327 PMID:11790512 PMID:11923462 PMID:12892653 PMID:15010698 PMID:15042275 PMID:15049517 PMID:17161392 PMID:17532787 PMID:17544385 PMID:17671965 PMID:18000554 PMID:18305460 PMID:18990547 PMID:19046384 PMID:19723785 PMID:20435100 PMID:20729865 PMID:27126842 NCBI chr 8:49,708,903...49,772,888 JBrowse link
G Drd3 dopamine receptor D3 decreases expression
decreases response to substance
increases expression
increases activity
affects expression
affects activity
multiple interactions
affects response to substance
ISO
EXP
Cocaine results in decreased expression of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of DRD3 mRNA
Cocaine results in increased activity of DRD3 protein
Cocaine affects the expression of DRD3 protein
Cocaine affects the activity of DRD3 protein
DRD3 protein results in decreased susceptibility to Cocaine
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]
CTD PMID:10523822 PMID:10943692 PMID:11120399 PMID:12099907 PMID:15056714 PMID:15100700 PMID:16026479 PMID:18566292 PMID:19046384 PMID:19217379 PMID:19723785 PMID:20435100 PMID:20456009 NCBI chr11:56,879,689...56,931,901 JBrowse link
G Drd4 dopamine receptor D4 increases response to substance
affects expression
ISO
EXP
DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA
CTD PMID:17671965 PMID:20187946 NCBI chr 1:196,396,366...196,400,824 JBrowse link
G Drd5 dopamine receptor D5 affects expression EXP Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr14:72,489,347...72,490,774 JBrowse link
G Drp2 dystrophin related protein 2 affects expression ISO Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:97,607,577...97,658,115 JBrowse link
G Dsp desmoplakin increases expression ISO Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr17:26,623,602...26,671,692 JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
increases phosphorylation
EXP Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein
CTD PMID:18822274 PMID:20187946 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression
increases expression
EXP Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr 1:252,538,408...252,555,320 JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions
increases expression
EXP 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr 1:197,167,392...197,184,285 JBrowse link
G Dvl1 dishevelled segment polarity protein 1 affects expression EXP Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 5:166,456,989...166,468,733 JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 4:33,852,597...34,166,159 JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression EXP Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr19:531,783...554,670 JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression EXP Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr12:41,312,367...41,314,742 JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Cocaine affects the expression of PECI mRNA CTD PMID:20187946 NCBI chr17:29,850,884...29,886,781 JBrowse link
G Edn1 endothelin 1 increases expression EXP
ISO
Cocaine results in increased expression of EDN1 protein CTD PMID:9714087 PMID:11948058 PMID:17420087 PMID:18813882 NCBI chr17:22,454,924...22,460,812 JBrowse link
G Ednra endothelin receptor type A increases expression ISO
EXP
Cocaine results in increased expression of EDNRA protein CTD PMID:17420087 PMID:18813882 NCBI chr19:30,233,540...30,303,727 JBrowse link
G Ednrb endothelin receptor type B affects expression EXP Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr15:80,640,839...80,672,115 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression EXP Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 8:79,341,554...79,344,784 JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 affects expression EXP Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr 3:168,265,893...168,275,071 JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr 1:205,860,713...205,871,319 JBrowse link
G Efcab3 EF-hand calcium binding domain 3 affects expression
decreases expression
EXP Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA
CTD PMID:17898221 PMID:20187946 NCBI chr10:89,583,526...90,077,260 JBrowse link
G Efna1 ephrin A1 affects expression EXP Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 2:174,681,676...174,690,306 JBrowse link
G Efna2 ephrin A2 affects expression EXP Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr 7:9,515,635...9,528,071 JBrowse link
G Efna3 ephrin A3 affects expression EXP Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 2:174,729,192...174,738,111 JBrowse link
G Efna4 ephrin A4 affects expression EXP Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 2:174,748,729...174,752,979 JBrowse link
G Efna5 ephrin A5 increases expression EXP Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr 9:102,316,753...102,595,480 JBrowse link
G Efnb1 ephrin B1 increases expression EXP Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709 PMID:17898221 NCBI chr  X:64,257,351...64,270,158 JBrowse link
G Efnb2 ephrin B2 increases expression EXP Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr16:80,783,389...80,827,420 JBrowse link
G Efnb3 ephrin B3 increases expression EXP Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr10:54,274,506...54,281,951 JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 affects expression EXP Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr10:87,804,893...87,852,181 JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr14:91,176,931...91,349,722 JBrowse link
G Egr1 early growth response 1 affects expression
decreases expression
increases expression
multiple interactions
increases response to substance
ISO
EXP
Cocaine affects the expression of EGR1 mRNA
Cocaine deficiency results in decreased expression of EGR1 mRNA
Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
EGR1 results in increased susceptibility to Cocaine
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]
CTD PMID:1347779 PMID:7905595 PMID:9890435 PMID:10971643 PMID:11860464 PMID:16339038 PMID:16459018 PMID:16738229 PMID:17851536 PMID:18311559 PMID:18355967 PMID:20187946 PMID:27126842 NCBI chr18:26,463,333...26,465,531 JBrowse link
G Egr2 early growth response 2 increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA
CTD PMID:20056891 PMID:20187946 PMID:27899881 NCBI chr20:21,051,270...21,056,322 JBrowse link
G Egr3 early growth response 3 affects expression
decreases expression
multiple interactions
increases expression
EXP
ISO
Cocaine affects the expression of EGR3 mRNA
Cocaine deficiency results in decreased expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine results in increased expression of EGR3 mRNA
CTD PMID:16459018 PMID:20187946 PMID:27126842 PMID:30158054 NCBI chr15:45,150,335...45,156,052 JBrowse link
G Egr4 early growth response 4 increases expression EXP Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 4:118,047,869...118,050,328 JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr 1:76,639,568...76,658,747 JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 decreases expression ISO Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 3:7,580,680...7,729,046 JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions
decreases response to substance
decreases expression
ISO Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
EHMT2 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein
CTD PMID:20056891 NCBI chr20:3,919,623...3,936,751 JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Cocaine results in increased expression of EIF1A mRNA; Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr18:39,325,695...39,338,043 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
EXP Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]
CTD PMID:17303341 NCBI chr 4:102,805,495...102,866,914 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr 6:97,672,829...97,697,499 JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression EXP Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr 1:259,902,767...259,932,976 JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression EXP Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr12:14,196,403...14,220,865 JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr 1:181,134,604...181,152,489 JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E affects expression EXP Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr 7:75,257,366...75,265,601 JBrowse link
G Eif4b eukaryotic translation initiation factor 4B multiple interactions
increases expression
ISO FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression
affects expression
increases expression
ISO
EXP
Cocaine results in decreased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA
CTD PMID:15009677 PMID:16710320 PMID:20187946 NCBI chr10:54,640,104...54,644,845 JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 9:40,222,769...40,277,482 JBrowse link
G Eif5b-ps1 eukaryotic translation initiation factor 5B, pseudogene 1 increases expression EXP Cocaine results in increased expression of EIF5B-PS1 mRNA CTD PMID:17898221 NCBI chr19:35,387,899...35,392,006 JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr 7:9,817,251...9,819,174 JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr17:44,286,495...44,822,788 JBrowse link
G Emc9 ER membrane protein complex subunit 9 affects expression EXP Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr15:29,071,881...29,076,098 JBrowse link
G Enah ENAH, actin regulator increases expression EXP Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr13:93,617,751...93,738,119 JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr 2:28,550,670...28,562,591 JBrowse link
G Enho energy homeostasis associated decreases expression ISO Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 5:56,800,980...56,802,777 JBrowse link
G Eno2 enolase 2 decreases expression
increases expression
ISO Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein
CTD PMID:12629581 PMID:17075605 NCBI chr 4:157,572,085...157,580,971 JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression ISO Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr 9:16,910,187...16,917,633 JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 3:8,213,575...8,219,094 JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 8:120,246,412...120,277,943 JBrowse link
G Epha1 Eph receptor A1 affects expression EXP Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 4:71,246,409...71,260,920 JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 5:153,605,644...153,634,115 JBrowse link
G Epha3 Eph receptor A3 affects expression EXP Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr11:1,138,485...1,474,102 JBrowse link
G Epha4 Eph receptor A4 affects expression
increases expression
EXP Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA
CTD PMID:15691709 PMID:17898221 NCBI chr 9:78,815,460...78,958,139 JBrowse link
G Epha5 EPH receptor A5 affects expression EXP Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr14:23,653,393...24,020,135 JBrowse link
G Epha7 Eph receptor A7 affects expression EXP Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 5:42,975,353...43,128,703 JBrowse link
G Epha8 Eph receptor A8 affects expression EXP Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 5:149,166,107...149,193,498 JBrowse link
G Ephb1 Eph receptor B1 increases expression ISO
EXP
Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA
CTD PMID:11146119 PMID:15691709 NCBI chr 8:102,507,549...102,944,839 JBrowse link
G Ephb2 Eph receptor B2 increases expression EXP Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 5:148,889,574...149,077,027 JBrowse link
G Ephb3 Eph receptor B3 affects expression EXP Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr11:79,840,668...79,859,467 JBrowse link
G Ephb4 EPH receptor B4 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA
CTD PMID:15691709 PMID:18000554 NCBI chr12:19,326,411...19,351,667 JBrowse link
G Ephb6 Eph receptor B6 affects expression EXP Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 4:70,491,973...70,507,230 JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr 2:34,926,962...35,028,440 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
EXP 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr10:91,326,889...91,421,201 JBrowse link
G Ess2 ess-2 splicing factor homolog decreases expression EXP Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr11:83,075,893...83,085,849 JBrowse link
G Etf1 eukaryotic translation termination factor 1 affects expression EXP Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr18:26,502,413...26,530,753 JBrowse link
G Etfa electron transfer flavoprotein subunit alpha affects expression EXP Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr 8:55,835,115...55,891,890 JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr17:33,506,289...33,698,246 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 increases expression ISO Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 5:4,863,501...5,101,483 JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 affects expression EXP Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr 3:154,335,558...154,519,006 JBrowse link
G Ezr ezrin decreases expression ISO Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr 1:46,967,961...47,011,505 JBrowse link
G Fadd Fas associated via death domain affects expression
multiple interactions
decreases expression
EXP Cocaine affects the expression of FADD mRNA
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]
Cocaine results in decreased expression of FADD protein modified form
CTD PMID:18580876 NCBI chr 1:199,743,200...199,745,746 JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 increases expression EXP Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr10:13,873,539...13,874,978 JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression ISO Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 8:99,543,877...99,569,499 JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression EXP Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr 7:130,632,368...130,659,353 JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression EXP Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr14:65,475,489...65,591,388 JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression EXP Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr12:15,826,864...15,885,423 JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression EXP Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr13:79,162,405...79,250,958 JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression EXP Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr15:79,906,795...79,926,678 JBrowse link
G Fbxo46 F-box protein 46 affects expression EXP Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr 1:78,770,059...78,786,582 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb decreases expression EXP Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr13:83,191,253...83,207,776 JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198 JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 9:76,439,164...76,443,603 JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression EXP Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 4:124,497,061...124,594,564 JBrowse link
G Fgf12 fibroblast growth factor 12 affects expression EXP Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr11:71,997,049...72,564,965 JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 2:120,236,328...120,290,673 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression EXP Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr16:66,492,445...66,546,731 JBrowse link
G Fh fumarate hydratase affects expression ISO Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr13:87,524,331...87,550,215 JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr12:19,708,558...19,723,392 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects expression EXP Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr 6:27,832,128...27,850,600 JBrowse link
G Fkbpl FKBP prolyl isomerase like affects expression EXP Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr20:4,099,845...4,101,315 JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 increases expression ISO Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr 3:127,994,491...128,008,137 JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 decreases expression EXP Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr10:12,774,644...12,794,373 JBrowse link
G Fmr1 FMRP translational regulator 1 decreases expression EXP Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Fndc1 fibronectin type III domain containing 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr 1:47,281,839...47,364,247 JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 5:141,481,593...141,491,257 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects expression
increases phosphorylation
decreases response to substance
increases activity
decreases expression
ISO
EXP
[Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine results in increased phosphorylation of FOS protein
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
FOS protein mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of FOS protein
Cocaine deficiency results in decreased expression of FOS protein; Cocaine results in decreased expression of FOS protein
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]
CTD PMID:1498673 PMID:2118661 PMID:7905595 PMID:10415707 PMID:10521585 PMID:10632609 PMID:10814832 PMID:10904129 PMID:10943692 PMID:10971643 PMID:11160452 PMID:11172061 PMID:11403691 PMID:11421588 PMID:11716816 PMID:11739600 PMID:11860464 PMID:11882344 PMID:12112414 PMID:12122080 PMID:12128156 PMID:12379259 PMID:12419516 PMID:12581847 PMID:12670717 PMID:12699766 PMID:12786985 PMID:12821175 PMID:14644470 PMID:14741756 PMID:15056714 PMID:15219685 PMID:15254092 PMID:15295023 PMID:15665076 PMID:15814102 PMID:16179556 PMID:16263220 PMID:16300424 PMID:16339038 PMID:16395306 PMID:16459018 PMID:16710312 PMID:16930414 PMID:16962079 PMID:17276011 PMID:17596442 PMID:17851536 PMID:18164822 PMID:18311559 PMID:18355967 PMID:18396266 PMID:18479823 PMID:18822274 PMID:18991842 PMID:19169671 PMID:19606084 PMID:19620976 PMID:20187946 PMID:20633205 PMID:20947769 PMID:25933444 PMID:27126842 PMID:27899881 PMID:31059705 NCBI chr 6:105,121,170...105,124,036 JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in increased expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]
CTD PMID:10103106 PMID:11391778 PMID:11739600 PMID:12417638 PMID:15056714 PMID:15814102 PMID:15926929 PMID:16263220 PMID:16674926 PMID:16710312 PMID:17898221 PMID:18293355 PMID:18355967 PMID:18822274 PMID:20056891 PMID:20633205 PMID:27899881 NCBI chr 1:78,954,312...78,961,492 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects expression
decreases expression
EXP
ISO
Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA
CTD PMID:12117546 PMID:12629581 NCBI chr 1:202,754,549...202,763,057 JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein
CTD PMID:15056714 PMID:15814102 NCBI chr 6:24,297,898...24,319,157 JBrowse link
G Foxc2 forkhead box C2 decreases expression EXP Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr19:49,186,034...49,188,736 JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr 2:136,312,168...136,390,603 JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Cocaine deficiency results in increased expression of FOXP1 mRNA CTD PMID:27126842 NCBI chr 4:131,559,599...132,155,092 JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression EXP Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr14:12,791,407...13,200,862 JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression EXP Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr 2:137,602,784...137,740,785 JBrowse link
G Frmd5 FERM domain containing 5 decreases expression EXP Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr 3:108,492,099...108,763,715 JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression EXP Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr 9:13,288,559...13,297,285 JBrowse link
G Fubp1 far upstream element binding protein 1 affects expression EXP Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 2:241,159,481...241,186,591 JBrowse link
G Fut8 fucosyltransferase 8 affects expression EXP Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr 6:95,948,230...96,176,677 JBrowse link
G Fzd6 frizzled class receptor 6 affects expression EXP Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr 7:70,055,012...70,086,781 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:152,201,081...152,220,863 JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA
CTD PMID:11793422 PMID:16076954 PMID:20187946 NCBI chr20:1,464,534...1,494,114 JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases phosphorylation EXP Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 5:60,947,517...61,288,104 JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 affects expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GABRA1 protein
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:20826313 PMID:23266428 PMID:32209479 NCBI chr10:26,595,151...26,650,611 JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr14:36,068,725...36,548,946 JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO
EXP
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:32209479 NCBI chr10:26,936,592...27,156,141 JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression
multiple interactions
EXP Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein
CTD PMID:20187946 PMID:20826313 NCBI chr 1:108,467,047...108,702,522 JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions
increases expression
ISO
EXP
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine deficiency results in increased expression of GABRG2 mRNA
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:27126842 PMID:32209479 NCBI chr10:26,376,805...26,463,680 JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein
CTD PMID:12629581 PMID:15295023 PMID:18611417 NCBI chr 3:55,369,704...55,410,335 JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions ISO GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr 1:200,650,439...200,655,302 JBrowse link
G Galk1 galactokinase 1 affects expression EXP Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr10:101,243,146...101,247,323 JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression EXP Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:15,489,015...15,568,849 JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression EXP Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr 6:100,168,943...100,250,718 JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr11:58,376,371...58,470,047 JBrowse link
G Gas2 growth arrest-specific 2 affects expression ISO Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr 1:101,452,361...101,582,619 JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 increases expression ISO Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]
CTD PMID:30393195 NCBI chr 8:78,629,899...78,668,547 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression
increases expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GCLM mRNA
Cocaine results in increased expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]
CTD PMID:20187946 PMID:30393195 NCBI chr 2:210,347,482...210,367,537 JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Cocaine deficiency results in increased expression of GCNT2 mRNA CTD PMID:27126842 NCBI chr17:23,796,859...23,901,625 JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression EXP Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 5:1,932,613...1,951,691 JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression EXP Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr 3:152,110,225...152,129,693 JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression EXP Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr 2:56,893,992...56,919,935 JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 5:25,214,309...25,225,222 JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
affects expression
ISO
EXP
Cocaine results in increased expression of GFAP protein
Cocaine results in decreased expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein
CTD PMID:11391778 PMID:11882367 PMID:12670315 PMID:15814102 PMID:20187946 NCBI chr10:87,852,891...87,861,631 JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression EXP Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr15:45,941,841...46,033,715 JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO
EXP
Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
CTD PMID:9413023 PMID:10657535 PMID:15099682 NCBI chr10:91,228,102...91,230,079 JBrowse link
G Gid8 GID complex subunit 8 homolog affects expression EXP Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr 3:167,826,006...167,836,759 JBrowse link
G Gimap1 GTPase, IMAP family member 1 affects expression EXP Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 4:77,687,581...77,691,468 JBrowse link
G Gimap5 GTPase, IMAP family member 5 affects expression EXP Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 4:77,693,417...77,701,025 JBrowse link
G Gins3 GINS complex subunit 3 decreases expression EXP Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr19:9,420,085...9,428,621 JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects expression EXP Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr19:24,474,291...24,487,083 JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 2:184,602,407...184,621,952 JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:66,501,848...66,509,783 JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression ISO Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr15:31,260,390...31,278,222 JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression EXP Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 5:139,680,670...139,683,588 JBrowse link
G Gjd2 gap junction protein, delta 2 affects expression EXP Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr 3:100,771,450...100,776,134 JBrowse link
G Gli2 GLI family zinc finger 2 decreases expression EXP Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr13:29,946,809...30,163,901 JBrowse link
G Glp2r glucagon-like peptide 2 receptor decreases expression EXP Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr10:52,402,748...52,465,908 JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions EXP Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]; Dronabinol inhibits the reaction [Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]] CTD PMID:32209479 NCBI chr10:39,625,853...39,727,897 JBrowse link
G Glrx3 glutaredoxin 3 affects expression EXP Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr 1:192,241,707...192,272,012 JBrowse link
G Gnao1 G protein subunit alpha o1 decreases expression
multiple interactions
ISO
EXP
Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form
CTD PMID:12629581 PMID:19457111 NCBI chr19:11,034,874...11,192,502 JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 8:108,350,935...108,355,671 JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 5:166,075,508...166,142,223 JBrowse link
G Gnb2 G protein subunit beta 2 affects expression EXP Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr12:19,159,002...19,164,021 JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 2:115,360,746...115,400,680 JBrowse link
G Gng12 G protein subunit gamma 12 affects expression EXP Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 4:96,011,118...96,134,767 JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]
CTD PMID:31059705 NCBI chr15:41,972,482...41,976,690 JBrowse link
G Gp2 glycoprotein 2 affects expression EXP Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr 1:173,797,057...173,812,619 JBrowse link
G Gpc5 glypican 5 increases expression
multiple interactions
ISO Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]
CTD PMID:18355967 NCBI chr15:92,207,275...93,644,054 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr12:15,217,217...15,222,679 JBrowse link
G Gphn gephyrin increases phosphorylation
multiple interactions
EXP Cocaine results in increased phosphorylation of GPHN protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]
CTD PMID:32312805 NCBI chr 6:96,954,365...97,483,617 JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr16:36,641,282...36,973,477 JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:28,057,788...28,204,409 JBrowse link
G Gpr157 G protein-coupled receptor 157 decreases expression EXP Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 5:160,550,703...160,566,432 JBrowse link
G Gpr3 G protein-coupled receptor 3 increases expression EXP Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 5:145,411,500...145,414,621 JBrowse link
G Gpr88 G-protein coupled receptor 88 affects expression
increases expression
EXP
ISO
Cocaine affects the expression of GPR88 mRNA
Cocaine deficiency results in increased expression of GPR88 mRNA
CTD PMID:20187946 PMID:27126842 NCBI chr 2:204,191,443...204,199,576 JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 affects expression EXP Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:98,765,581...98,772,685 JBrowse link
G Gpsm1 G-protein signaling modulator 1 affects expression EXP Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 3:9,140,816...9,167,828 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein] CTD PMID:30393195 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
affects response to substance
multiple interactions
ISO Cocaine results in increased expression of GPX1 protein
GPX1 protein affects the susceptibility to Cocaine
GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
CTD PMID:31059705 NCBI chr 8:109,026,905...109,028,031 JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr10:100,881,404...100,949,193 JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
increases response to substance
increases expression
decreases phosphorylation
multiple interactions
affects expression
ISO
EXP
GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine results in increased phosphorylation of GRIA1 protein
GRIA1 protein affects the susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
Cocaine results in decreased phosphorylation of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
CTD PMID:9886066 PMID:11268215 PMID:11801363 PMID:12511956 PMID:12787079 PMID:14684464 PMID:15140200 PMID:16473939 PMID:16794574 PMID:17680995 PMID:17898221 PMID:18278040 PMID:18430032 PMID:18701074 PMID:19070590 PMID:19105975 PMID:19457111 PMID:19474322 PMID:19629758 PMID:20187946 PMID:20600170 PMID:23499958 PMID:24810662 PMID:28194001 NCBI chr10:41,210,713...41,527,283 JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression
decreases response to substance
multiple interactions
affects expression
ISO
EXP
Cocaine results in increased expression of GRIA2 protein
GRIA2 results in decreased susceptibility to Cocaine
Cocaine results in increased phosphorylation of and affects the localization of GRIA2 protein
Cocaine results in increased expression of GRIA2 mRNA
Cocaine affects the expression of GRIA2 mRNA; Cocaine affects the expression of GRIA2 protein
CTD PMID:9886066 PMID:12511956 PMID:12787079 PMID:15140200 PMID:16363995 PMID:18945913 PMID:19105975 PMID:20187946 PMID:20534846 NCBI chr 2:165,949,379...166,069,510 JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression
affects expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GRIA3 mRNA
Cocaine affects the expression of GRIA3 protein
Cocaine results in increased expression of GRIA3 protein
CTD PMID:9886066 PMID:12511956 PMID:15140200 PMID:16363995 NCBI chr  X:120,238,515...120,504,106 JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 affects expression ISO
EXP
Cocaine affects the expression of GRIA4 mRNA
Cocaine affects the expression of GRIA4 protein
CTD PMID:9886066 PMID:15140200 NCBI chr 8:1,562,118...2,035,035 JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 affects expression EXP Cocaine affects the expression of GRIK1 mRNA; Cocaine affects the expression of GRIK1 protein CTD PMID:12358776 PMID:15140200 NCBI chr11:27,169,739...27,571,131 JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 affects expression EXP Cocaine affects the expression of GRIK2 protein CTD PMID:15140200 NCBI chr20:52,135,325...52,833,061 JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 affects expression EXP Cocaine affects the expression of GRIK3 protein CTD PMID:15140200 NCBI chr 5:137,767,865...137,989,617 JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression EXP Cocaine affects the expression of GRIK5 protein CTD PMID:15140200 NCBI chr 1:80,605,878...80,667,896 JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
affects response to substance
increases expression
affects phosphorylation
affects expression
decreases expression
EXP
ISO
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIN1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIN1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]
GRIN1 protein affects the susceptibility to Cocaine
Cocaine results in increased expression of GRIN1 mRNA; Cocaine results in increased expression of GRIN1 protein
Cocaine affects the expression of GRIN1 mRNA; Cocaine affects the expression of GRIN1 protein
Cocaine results in decreased expression of GRIN1 mRNA
CTD PMID:9886066 PMID:11032893 PMID:11801363 PMID:12457264 PMID:12670717 PMID:12787079 PMID:15140200 PMID:16363995 PMID:17680995 PMID:19474322 PMID:20187946 PMID:20600170 NCBI chr 3:8,103,680...8,130,603 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
increases expression
affects expression
ISO
EXP
HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]
ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2A protein]
Cocaine results in increased expression of GRIN2A mRNA; Cocaine results in increased expression of GRIN2A protein
Cocaine affects the expression of GRIN2A mRNA; Cocaine affects the expression of GRIN2A protein
CTD PMID:17898221 PMID:17988634 PMID:19105975 PMID:19306440 PMID:19474322 PMID:20187946 NCBI chr10:5,630,684...6,043,341 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
affects response to substance
multiple interactions
affects expression
decreases phosphorylation
EXP Cocaine results in increased expression of GRIN2B protein
GRIN2B protein affects the susceptibility to Cocaine
Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in decreased phosphorylation of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]
Cocaine affects the expression of GRIN2B mRNA; Cocaine affects the expression of GRIN2B protein
CTD PMID:11032893 PMID:11801363 PMID:15140200 PMID:16794574 PMID:19105975 PMID:19306440 PMID:19474322 PMID:20187946 NCBI chr 4:168,580,824...169,044,110 JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C affects expression EXP Cocaine affects the expression of GRIN2C mRNA CTD PMID:20187946 NCBI chr10:100,488,430...100,507,083 JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression
affects expression
EXP Cocaine results in increased expression of GRIN2D mRNA
Cocaine affects the expression of GRIN2D mRNA
CTD PMID:16076954 PMID:20187946 NCBI chr 1:96,306,871...96,346,994 JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A affects expression EXP Cocaine affects the expression of GRIN3A protein CTD PMID:15140200 NCBI chr 5:64,006,847...64,206,408 JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B affects expression EXP Cocaine affects the expression of GRIN3B protein CTD PMID:15140200 NCBI chr 7:9,730,861...9,737,183 JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP Cocaine results in increased expression of GRINA mRNA CTD PMID:16076954 NCBI chr 7:107,962,194...107,965,368 JBrowse link
G Grip1 glutamate receptor interacting protein 1 increases phosphorylation
multiple interactions
EXP
ISO
Cocaine results in increased phosphorylation of GRIP1 protein
[Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA
CTD PMID:18355967 PMID:19439608 NCBI chr 7:54,934,856...55,592,274 JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression EXP Cocaine results in increased expression of GRIP2 mRNA CTD PMID:16076954 NCBI chr 4:124,271,456...124,356,538 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 affects expression
increases expression
EXP Cocaine affects the expression of GRK2 mRNA
Cocaine results in increased expression of GRK2 mRNA
CTD PMID:16076954 PMID:20187946 NCBI chr 1:201,581,480...201,601,580 JBrowse link
G Grk6 G protein-coupled receptor kinase 6 affects expression EXP Cocaine affects the expression of GRK6 mRNA CTD PMID:20187946 NCBI chr17:9,177,018...9,192,644 JBrowse link
G Grm1 glutamate metabotropic receptor 1 affects response to substance ISO GRM1 affects the susceptibility to Cocaine CTD PMID:19597494 NCBI chr 1:5,058,285...5,453,170 JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases activity
affects expression
decreases activity
EXP Cocaine results in increased activity of GRM2 protein
Cocaine affects the expression of GRM2 protein
Cocaine results in decreased activity of GRM2 protein
CTD PMID:18673447 PMID:19105975 PMID:20416862 NCBI chr 8:107,280,099...107,293,159 JBrowse link
G Grm3 glutamate metabotropic receptor 3 increases activity
affects expression
EXP Cocaine results in increased activity of GRM3 protein
Cocaine affects the expression of GRM3 protein
CTD PMID:19105975 PMID:20416862 NCBI chr 4:24,364,854...24,643,972 JBrowse link
G Grm5 glutamate metabotropic receptor 5 affects expression
increases expression
multiple interactions
affects localization
decreases response to substance
ISO
EXP
Cocaine affects the expression of GRM5 mRNA
Cocaine deficiency results in increased expression of GRM5 mRNA
Cocaine results in decreased expression of and results in decreased activity of GRM5 protein
Cocaine results in increased expression of GRM5 mRNA
Cocaine affects the expression of GRM5 protein
Cocaine affects the localization of GRM5 protein
GRM5 mutant form results in decreased susceptibility to Cocaine
CTD PMID:9886066 PMID:15295029 PMID:17898221 PMID:19105975 PMID:19118598 PMID:20416862 PMID:20534846 PMID:20826661 PMID:24810662 PMID:27126842 NCBI chr 1:141,310,069...141,884,980 JBrowse link
G Grm7 glutamate metabotropic receptor 7 increases expression EXP Cocaine results in increased expression of GRM7 mRNA CTD PMID:16076954 NCBI chr 4:143,730,862...144,613,230 JBrowse link
G Grpr gastrin releasing peptide receptor affects expression EXP Cocaine affects the expression of GRPR mRNA CTD PMID:20187946 NCBI chr  X:30,998,425...31,038,442 JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects expression EXP Cocaine affects the expression of GSK3A mRNA CTD PMID:12117546 NCBI chr 1:80,815,843...80,825,732 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
ISO Cocaine results in decreased phosphorylation of and results in increased activity of GSK3B protein
Cocaine results in increased activity of GSK3B protein
CTD PMID:19328817 NCBI chr11:62,498,997...62,648,665 JBrowse link
G Gsn gelsolin decreases expression ISO Cocaine results in decreased expression of GSN mRNA CTD PMID:12629581 NCBI chr 3:18,585,166...18,638,404 JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP Cocaine deficiency results in increased expression of GSR mRNA CTD PMID:22860061 NCBI chr16:58,482,209...58,525,256 JBrowse link
G Gsto1 glutathione S-transferase omega 1 affects expression ISO Cocaine affects the expression of GSTO1 protein CTD PMID:19393250 NCBI chr 1:246,721,089...246,731,228 JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance ISO GSTP1 polymorphism affects the susceptibility to Cocaine CTD PMID:16272961 NCBI chr 1:201,337,762...201,340,230 JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Cocaine results in increased expression of GUCY1A1 mRNA CTD PMID:17898221 NCBI chr 2:167,418,615...167,482,293 JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP Cocaine results in increased expression of GUCY1B1 mRNA CTD PMID:17898221 NCBI chr 2:167,348,824...167,398,983 JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP Cocaine results in decreased expression of GYG1 protein CTD PMID:25100957 NCBI chr 2:102,611,888...102,653,916 JBrowse link
G Gzmm granzyme M affects expression EXP Cocaine affects the expression of GZMM mRNA CTD PMID:20187946 NCBI chr 7:10,011,065...10,016,841 JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 affects expression EXP Cocaine affects the expression of HAND1 mRNA CTD PMID:20187946 NCBI chr10:42,006,646...42,009,213 JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 increases expression ISO Cocaine results in increased expression of HCN2 mRNA CTD PMID:18000554 NCBI chr 7:9,969,801...9,988,839 JBrowse link
G Hcrt hypocretin neuropeptide precursor affects expression
multiple interactions
EXP Cocaine affects the expression of HCRT mRNA
Methadone affects the reaction [Cocaine affects the expression of HCRT mRNA]
CTD PMID:18990547 NCBI chr10:85,689,992...85,691,206 JBrowse link
G Hcrtr2 hypocretin receptor 2 affects expression EXP Cocaine affects the expression of HCRTR2 protein CTD PMID:17623047 NCBI chr 8:76,989,834...77,105,893 JBrowse link
G Hdac10 histone deacetylase 10 affects expression EXP Cocaine affects the expression of HDAC10 mRNA CTD PMID:20187946 NCBI chr 7:120,199,126...120,205,850 JBrowse link
G Hdac5 histone deacetylase 5 decreases activity
decreases response to substance
multiple interactions
ISO Cocaine results in decreased activity of HDAC5 protein
HDAC5 results in decreased susceptibility to Cocaine
Cocaine results in increased phosphorylation of and results in increased localization of HDAC5 protein; HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNK4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNQ5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of PRM1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RAPGEF6 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RGS20 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of SUV39H1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of TACR1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of WNT5A mRNA]
CTD PMID:17988634 NCBI chr10:87,152,978...87,187,921 JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions
decreases expression
EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in decreased expression of HDAC6 protein] CTD PMID:32312805 NCBI chr  X:14,550,645...14,572,445 JBrowse link
G Hdc histidine decarboxylase affects response to substance ISO HDC gene mutant form affects the susceptibility to Cocaine CTD PMID:17072589 NCBI chr 3:113,847,256...113,865,334 JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression EXP Cocaine results in decreased expression of HECW2 mRNA CTD PMID:17898221 NCBI chr 9:55,359,462...55,753,106 JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 increases expression EXP Cocaine results in increased expression of HERC1 mRNA CTD PMID:17898221 NCBI chr 8:66,857,169...67,070,318 JBrowse link
G Hhip Hedgehog-interacting protein decreases expression EXP Cocaine results in decreased expression of HHIP mRNA CTD PMID:17898221 NCBI chr19:27,863,684...27,952,528 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Cocaine results in decreased expression of HIF1A mRNA CTD PMID:12629581 NCBI chr 6:92,624,059...92,669,262 JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A affects expression
increases expression
EXP Cocaine affects the expression of HIGD1A mRNA
Cocaine results in increased expression of HIGD1A protein
CTD PMID:20187946 PMID:25100957 NCBI chr 8:121,514,152...121,523,382 JBrowse link
G Hmga1 high mobility group AT-hook 1 affects expression EXP Cocaine affects the expression of HMGA1 mRNA CTD PMID:20187946 NCBI chr20:5,611,088...5,618,755 JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Cocaine results in increased expression of HMGCS1 mRNA CTD PMID:12117546 NCBI chr 2:51,649,368...51,667,100 JBrowse link
G Homer1 homer scaffold protein 1 increases response to substance
increases expression
affects expression
multiple interactions
decreases response to substance
ISO
EXP
HOMER1 polymorphism results in increased susceptibility to Cocaine
Cocaine results in increased expression of HOMER1 protein
Cocaine affects the expression of HOMER1 mRNA; Cocaine affects the expression of HOMER1 protein
Cocaine affects the expression of and affects the localization of HOMER1 protein
HOMER1 protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of HOMER1 mRNA
CTD PMID:15294147 PMID:16314758 PMID:18355967 PMID:19105975 PMID:19118598 PMID:19306440 PMID:20187946 PMID:20534846 NCBI chr 2:24,542,777...24,645,715 JBrowse link
G Homer2 homer scaffold protein 2 multiple interactions
affects expression
decreases response to substance
decreases expression
ISO
EXP
Cocaine affects the reaction [HOMER2 mutant form results in decreased secretion of Excitatory Amino Acid Agents]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]
Cocaine affects the expression of HOMER2 mRNA
HOMER2 protein results in decreased susceptibility to Cocaine; HOMER2 results in decreased susceptibility to Cocaine
CTD PMID:14684444 PMID:15294147 PMID:15545022 PMID:18355967 PMID:20187946 NCBI chr 1:135,558,977...135,659,780 JBrowse link
G Homer3 homer scaffold protein 3 affects expression EXP Cocaine affects the expression of HOMER3 mRNA CTD PMID:20187946 NCBI chr16:19,132,177...19,142,739 JBrowse link
G Hpca hippocalcin increases expression ISO Cocaine deficiency results in increased expression of HPCA mRNA CTD PMID:27126842 NCBI chr 5:141,455,616...141,466,252 JBrowse link
G Hpcal1 hippocalcin-like 1 decreases expression ISO Cocaine results in decreased expression of HPCAL1 mRNA CTD PMID:15009677 NCBI chr 6:40,478,182...40,584,721 JBrowse link
G Hpcal4 hippocalcin-like 4 affects expression
increases expression
EXP Cocaine affects the expression of HPCAL4 mRNA
Cocaine results in increased expression of HPCAL4 mRNA
CTD PMID:17898221 PMID:20187946 NCBI chr 5:135,454,477...135,466,417 JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression EXP Cocaine results in increased expression of HPD mRNA CTD PMID:27899881 NCBI chr12:33,381,397...33,392,750 JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 affects expression EXP Cocaine affects the expression of HPS1 mRNA CTD PMID:20187946 NCBI chr 1:241,551,180...241,577,292 JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of HS3ST2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]
CTD PMID:18355967 NCBI chr 1:175,956,161...176,077,400 JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP Cocaine results in decreased expression of HSD17B6 mRNA CTD PMID:17898221 NCBI chr 7:422,466...442,008 JBrowse link
G Hsf1 heat shock transcription factor 1 affects expression EXP Cocaine affects the expression of HSF1 mRNA CTD PMID:20187946 NCBI chr 7:108,196,040...108,223,011 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Cocaine deficiency results in increased expression of HSP90AA1 mRNA CTD PMID:22860061 NCBI chr 6:129,702,376...129,707,907 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Cocaine results in decreased expression of HSP90AB1 mRNA CTD PMID:17898221 NCBI chr 9:15,432,986...15,438,358 JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Cocaine results in increased expression of HSPA1A mRNA CTD PMID:20056891
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression
increases expression
ISO
EXP
Cocaine affects the expression of HSPA1B mRNA
Cocaine results in increased expression of HSPA1B mRNA
CTD PMID:15681117 PMID:27899881 NCBI chr20:3,855,104...3,859,148 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO
EXP
Cocaine results in increased expression of HSPA5 mRNA
Cocaine results in increased expression of HSPA5 mRNA; Cocaine results in increased expression of HSPA5 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]
CTD PMID:15009677 PMID:17303341 PMID:23644055 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
EXP Anisomycin inhibits the reaction [Cocaine results in increased expression of HSPA9 protein] CTD PMID:12422371 NCBI chr18:26,536,131...26,554,294 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Cocaine results in increased expression of HSPB1 mRNA CTD PMID:27899881 NCBI chr12:20,794,014...20,795,675 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Cocaine affects the expression of HSPD1 protein CTD PMID:19393250 NCBI chr 9:56,579,195...56,590,011 JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Cocaine] results in decreased phosphorylation of HTATSF1 protein CTD PMID:32312805 NCBI chr  X:134,935,426...134,949,607 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] CTD PMID:9723786 NCBI chr 2:36,694,174...36,695,442 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B increases response to substance
affects activity
multiple interactions
ISO
EXP
HTR1B mutant form results in increased susceptibility to Cocaine
Cocaine affects the activity of HTR1B protein
[3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [CP 94253 binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine
CTD PMID:9603521 PMID:9822762 PMID:17074068 NCBI chr 8:82,513,572...82,534,892 JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D affects expression EXP Cocaine affects the expression of HTR1D mRNA CTD PMID:20187946 NCBI chr 5:148,655,979...148,676,534 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects activity
affects response to substance
ISO
EXP
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Alprenolol co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; [Metergoline binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Methiothepin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Mianserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Yohimbine co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; Cocaine inhibits the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]
Cocaine affects the activity of HTR2A protein
Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]; Ketanserin inhibits the reaction [Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]]
HTR2A protein affects the susceptibility to Cocaine
CTD PMID:8392199 PMID:10764922 PMID:10773209 PMID:10773215 PMID:17259860 NCBI chr15:49,950,035...50,022,188 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
decreases expression
increases response to substance
ISO
EXP
[1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; [6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; HTR2C protein affects the reaction [Cocaine results in increased abundance of Dopamine]
Cocaine results in decreased expression of HTR2C mRNA
HTR2C mutant form results in increased susceptibility to Cocaine
CTD PMID:10541732 PMID:12427861 PMID:16076954 NCBI chr  X:110,640,777...110,870,288 JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases response to substance
multiple interactions
ISO
EXP
HTR3A mutant form results in decreased susceptibility to Cocaine
Cocaine inhibits the reaction [Serotonin results in increased activity of HTR3A protein]
CTD PMID:17559417 PMID:32209479 NCBI chr 8:49,242,018...49,254,475 JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 affects response to substance EXP HTR4 protein affects the susceptibility to Cocaine CTD PMID:9806222 NCBI chr18:55,765,981...55,949,921 JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 multiple interactions EXP [Ro 4-6790 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine; [SB 271046 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine CTD PMID:20426879 NCBI chr 5:151,295,269...151,312,853 JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 decreases expression EXP Cocaine results in decreased expression of HVCN1 mRNA CTD PMID:27899881 NCBI chr12:34,341,673...34,370,010 JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP Cocaine results in increased expression of ICAM1 mRNA CTD PMID:10864098 NCBI chr 8:19,553,063...19,565,438 JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 affects response to substance ISO ICE2 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 8:70,043,419...70,085,217 JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha affects expression EXP Cocaine affects the expression of IDH3A mRNA CTD PMID:20187946 NCBI chr 8:54,971,694...54,991,085 JBrowse link
G Ier5 immediate early response 5 affects expression EXP Cocaine affects the expression of IER5 mRNA CTD PMID:20187946 NCBI chr13:67,270,134...67,272,226 JBrowse link
G Ifng interferon gamma affects secretion
decreases expression
multiple interactions
ISO Cocaine affects the secretion of IFNG protein
Cocaine results in decreased expression of IFNG mRNA; Cocaine results in decreased expression of IFNG protein
[Cocaine co-treated with Heroin] results in increased expression of IFNG protein
CTD PMID:9787120 PMID:16766138 PMID:29673861 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Ifrd1 interferon-related developmental regulator 1 affects expression EXP Cocaine affects the expression of IFRD1 mRNA CTD PMID:20187946 NCBI chr 6:57,269,395...57,317,833 JBrowse link
G Ift81 intraflagellar transport 81 increases expression EXP Cocaine results in increased expression of IFT81 mRNA CTD PMID:17898221 NCBI chr12:33,957,744...34,037,164 JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression EXP Cocaine affects the expression of IGF1R mRNA CTD PMID:20187946 NCBI chr 1:121,549,839...121,838,545 JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Cocaine results in decreased expression of IGF2 mRNA CTD PMID:16076954 NCBI chr 1:197,814,409...197,831,802 JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression EXP Cocaine results in decreased expression of IGFBP2 mRNA CTD PMID:16076954 NCBI chr 9:74,415,574...74,442,945 JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 affects expression EXP Cocaine affects the expression of IGSF8 mRNA CTD PMID:20187946 NCBI chr13:84,770,348...84,781,534 JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects expression EXP Cocaine affects the expression of IKBKB mRNA CTD PMID:20187946 NCBI chr16:69,319,487...69,373,251 JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
decreases secretion
ISO [Cocaine co-treated with Heroin] results in increased expression of IL10 protein
Cocaine results in increased expression of IL10 protein
Cocaine results in decreased secretion of IL10 protein
CTD PMID:9787120 PMID:16766138 NCBI chr13:42,472,625...42,477,308 JBrowse link
G Il16 interleukin 16 decreases expression EXP Cocaine results in decreased expression of IL16 mRNA CTD PMID:27899881 NCBI chr 1:137,617,702...137,718,022 JBrowse link
G Il18bp interleukin 18 binding protein affects expression EXP Cocaine affects the expression of IL18BP mRNA CTD PMID:20187946 NCBI chr 1:156,372,923...156,374,963 JBrowse link
G Il1a interleukin 1 alpha affects expression EXP Cocaine affects the expression of IL1A mRNA CTD PMID:20187946 NCBI chr 3:116,526,601...116,537,055 JBrowse link
G Il1b interleukin 1 beta increases expression ISO Cocaine results in increased expression of IL1B mRNA CTD PMID:20948987 PMID:26558777 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Cocaine co-treated with Heroin] results in increased expression of IL2 protein CTD PMID:16766138 NCBI chr 2:120,004,862...120,009,566 JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases secretion ISO Cocaine results in decreased secretion of IL2RA protein CTD PMID:1452400 NCBI chr17:66,849,974...66,898,665 JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Cocaine co-treated with Heroin] results in increased expression of IL4 protein CTD PMID:16766138 NCBI chr10:37,771,203...37,776,750 JBrowse link
G Il4i1 interleukin 4 induced 1 decreases expression EXP Cocaine results in decreased expression of IL4I1 mRNA CTD PMID:17898221 NCBI chr 1:95,299,457...95,324,564 JBrowse link
G Il6 interleukin 6 decreases expression
affects response to substance
multiple interactions
increases expression
ISO
EXP
Cocaine results in decreased expression of IL6 protein
IL6 protein affects the susceptibility to Cocaine
[IL6 protein affects the susceptibility to Cocaine] which affects the expression of TNF mRNA; [IL6 protein affects the susceptibility to Cocaine] which affects the expression of TNF protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased phosphorylation of STAT3 protein]]; IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]; IL6 protein affects the reaction [Cocaine results in increased phosphorylation of STAT3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]; TNF protein affects the reaction [IL6 protein affects the susceptibility to Cocaine]
Cocaine results in increased expression of IL6 mRNA; Cocaine results in increased expression of IL6 protein
CTD PMID:10864098 PMID:17068203 PMID:29673861 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Il6r interleukin 6 receptor affects response to substance ISO IL6R protein affects the susceptibility to Cocaine CTD PMID:29673861 NCBI chr 2:175,289,157...175,347,719 JBrowse link
G Ilk integrin-linked kinase multiple interactions
increases expression
EXP Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased expression of SYN1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
Cocaine results in increased expression of ILK protein
CTD PMID:18702665 PMID:19629758 NCBI chr 1:160,088,839...160,095,140 JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha multiple interactions
decreases expression
ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA
Cocaine results in decreased expression of INA mRNA
CTD PMID:18355967 NCBI chr 1:245,896,775...245,908,330 JBrowse link
G Inha inhibin subunit alpha decreases expression ISO Cocaine results in decreased expression of INHA mRNA CTD PMID:18000554 NCBI chr 9:76,994,465...76,997,366 JBrowse link
G Ins2 insulin 2 decreases expression ISO Cocaine results in decreased expression of INS protein CTD PMID:18346162 NCBI chr 1:197,843,277...197,992,522 JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO Cocaine results in decreased expression of IRF9 mRNA CTD PMID:12629581 NCBI chr15:29,095,474...29,101,924 JBrowse link
G Irs2 insulin receptor substrate 2 increases expression EXP Cocaine results in increased expression of IRS2 mRNA CTD PMID:27899881 NCBI chr16:78,488,249...78,512,482 JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO Cocaine affects the expression of ITGB1 protein CTD PMID:19073234 NCBI chr19:56,705,123...56,753,199 JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 increases expression ISO Cocaine results in increased expression of ITGB1BP1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 6:40,820,693...40,836,074 JBrowse link
G Itgb3 integrin subunit beta 3 affects expression ISO Cocaine affects the expression of ITGB3 protein CTD PMID:19073234 NCBI chr10:89,509,917...89,564,679 JBrowse link
G Itgb5 integrin subunit beta 5 affects expression EXP Cocaine affects the expression of ITGB5 mRNA CTD PMID:20187946 NCBI chr11:66,828,428...66,944,231 JBrowse link
G Itgb6 integrin subunit beta 6 increases expression ISO Cocaine results in increased expression of ITGB6 mRNA CTD PMID:18000554 NCBI chr 3:45,046,295...45,170,532 JBrowse link
G Itgb7 integrin subunit beta 7 decreases expression EXP Cocaine results in decreased expression of ITGB7 mRNA CTD PMID:17898221 NCBI chr 7:133,347,927...133,364,955 JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B increases expression EXP Cocaine results in increased expression of ITPKB mRNA CTD PMID:16076954 NCBI chr13:92,069,160...92,164,281 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions
increases expression
ISO
EXP
[Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA
Cocaine results in increased expression of ITPR1 protein
CTD PMID:18355967 PMID:25100957 NCBI chr 4:141,187,377...141,554,240 JBrowse link
G Jag2 jagged canonical Notch ligand 2 affects expression EXP Cocaine affects the expression of JAG2 mRNA CTD PMID:20187946 NCBI chr 6:131,983,056...132,005,359 JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation
multiple interactions
ISO Cocaine results in increased phosphorylation of JAK2 protein
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased phosphorylation of JAK2 protein]; IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]; TNF protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]
CTD PMID:29673861 NCBI chr 1:226,995,334...227,054,381 JBrowse link
G Jakmip2 janus kinase and microtubule interacting protein 2 increases expression EXP Cocaine results in increased expression of JAKMIP2 mRNA CTD PMID:17898221 NCBI chr18:35,532,552...35,747,938 JBrowse link
G Jdp2 Jun dimerization protein 2 affects expression EXP Cocaine affects the expression of JDP2 mRNA CTD PMID:20187946 NCBI chr 6:105,261,619...105,302,386 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects expression
ISO
EXP
Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
Cocaine results in increased expression of JUN protein modified form
Cocaine affects the expression of JUN protein
CTD PMID:15814102 PMID:16179556 PMID:17635674 PMID:18355967 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression
increases expression
multiple interactions
ISO
EXP
Cocaine affects the expression of JUNB protein
Cocaine results in increased expression of JUNB mRNA
Cocaine results in increased expression of JUNB protein
Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of JUNB protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of JUNB mRNA]
Cocaine affects the expression of JUNB mRNA
SL 327 inhibits the reaction [Cocaine results in increased expression of JUNB protein]
CTD PMID:1347779 PMID:11860464 PMID:12122080 PMID:15814102 PMID:16263220 PMID:18355967 PMID:20187946 NCBI chr19:23,176,265...23,178,049 JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Cocaine results in decreased expression of JUND protein
[JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine
CTD PMID:15814102 PMID:20056891 NCBI chr16:18,734,121...18,735,799 JBrowse link
G Jup junction plakoglobin affects expression EXP Cocaine affects the expression of JUP mRNA CTD PMID:20187946 NCBI chr10:85,300,438...85,327,378 JBrowse link
G Kalrn kalirin, RhoGEF kinase affects expression EXP Cocaine affects the expression of KALRN mRNA CTD PMID:20187946 NCBI chr11:66,198,155...66,803,166 JBrowse link
G Katnb1 katanin regulatory subunit B1 affects expression EXP Cocaine affects the expression of KATNB1 mRNA CTD PMID:20187946 NCBI chr19:9,921,216...9,940,853 JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 multiple interactions ISO Cocaine affects the reaction [NTRK2 protein affects the expression of KCNA2 mRNA] CTD PMID:20947769 NCBI chr 2:194,704,555...194,718,387 JBrowse link
G Kcna6 potassium voltage-gated channel subfamily A member 6 increases expression EXP Cocaine results in increased expression of KCNA6 mRNA CTD PMID:16076954 NCBI chr 4:159,542,941...159,576,189 JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of KCNAB1 mRNA
Cocaine affects the expression of KCNAB1 mRNA
CTD PMID:18000554 PMID:20187946 NCBI chr 2:149,137,025...149,603,540 JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 multiple interactions
affects expression
ISO
EXP
Cocaine affects the reaction [NTRK2 protein affects the expression of KCNB1 mRNA]
Cocaine affects the expression of KCNB1 mRNA
CTD PMID:20187946 PMID:20947769 NCBI chr 3:155,820,255...155,913,383 JBrowse link
G Kcnd1 potassium voltage-gated channel subfamily D member 1 multiple interactions ISO Cocaine affects the reaction [NTRK2 protein affects the expression of KCND1 mRNA] CTD PMID:20947769 NCBI chr  X:14,661,688...14,678,745 JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression EXP Cocaine results in decreased expression of KCND2 mRNA CTD PMID:16076954 NCBI chr 4:49,775,812...50,277,746 JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 increases expression EXP Cocaine results in increased expression of KCND3 mRNA CTD PMID:17898221 NCBI chr 2:192,937,950...193,155,345 JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 affects expression EXP Cocaine affects the expression of KCNIP3 mRNA CTD PMID:20187946 NCBI chr 3:114,677,027...114,742,923 JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 increases expression EXP Cocaine results in increased expression of KCNJ10 mRNA CTD PMID:16076954 NCBI chr13:84,802,026...84,835,383 JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 decreases response to substance ISO KCNJ11 results in decreased susceptibility to Cocaine CTD PMID:20443920 NCBI chr 1:96,591,048...96,594,574 JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO Cocaine affects the reaction [NTRK2 protein affects the expression of KCNJ4 mRNA] CTD PMID:20947769 NCBI chr 7:111,047,097...111,074,151 JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 affects expression
increases expression
decreases expression
EXP
ISO
Cocaine affects the expression of KCNJ6 mRNA
Cocaine results in increased expression of KCNJ6 mRNA
Cocaine results in decreased expression of KCNJ6 mRNA
CTD PMID:12629581 PMID:17898221 PMID:20187946 NCBI chr11:34,061,705...34,309,128 JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO Cocaine affects the reaction [NTRK2 protein affects the expression of KCNJ8 mRNA] CTD PMID:20947769 NCBI chr&nbs