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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:27953 term browser browse the term
Definition:An indole alkaloid that has formula C15H21N3O2.
Synonyms:exact_synonym: (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate
 related_synonym: Antilirium;   Eserine;   Formula=C15H21N3O2;   InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1;   InChIKey=PIJVFDBKTWXHHD-HIFRSBDPSA-N;   Physostol;   SMILES=[H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)NC)ccc1N2C
 alt_id: CHEBI:26108;   CHEBI:8187
 xref: Beilstein:91230;   CAS:57-47-6;   CAS:57-64-7;   DrugBank:DB00981;   Drug_Central:2159;   KEGG:C06535;   KEGG:D00196;   KNApSAcK:C00001757;   LINCS:LSM-2558
 xref_mesh: MESH:D010830

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physostigmine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase decreases activity
multiple interactions
EXP Physostigmine results in decreased activity of ACHE protein
Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]
CTD PMID:21414391 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,324...8,739,149
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  CHEBI ontology 880
    role 860
      biological role 860
        pharmacological role 385
          neurotransmitter agent 146
            miotic 1
              physostigmine 1
                physostigmine salicylate 0
Path 2
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  CHEBI ontology 880
    subatomic particle 865
      composite particle 865
        hadron 865
          baryon 865
            nucleon 865
              atomic nucleus 865
                atom 865
                  main group element atom 855
                    p-block element atom 852
                      carbon group element atom 828
                        carbon atom 827
                          organic molecular entity 827
                            organic group 392
                              organic divalent group 390
                                organodiyl group 390
                                  carbonyl group 389
                                    carbonyl compound 389
                                      carboxylic ester 233
                                        carbamate ester 11
                                          physostigmine 1
                                            physostigmine salicylate 0
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