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ONTOLOGY REPORT - ANNOTATIONS


Term:physostigmine
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Accession:CHEBI:27953 term browser browse the term
Definition:An indole alkaloid that has formula C15H21N3O2.
Synonyms:exact_synonym: (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate
 related_synonym: Antilirium;   Eserine;   Formula=C15H21N3O2;   InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1;   InChIKey=PIJVFDBKTWXHHD-HIFRSBDPSA-N;   Physostol;   SMILES=[H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)NC)ccc1N2C
 alt_id: CHEBI:26108;   CHEBI:8187
 xref: Beilstein:91230 "Beilstein";   CAS:57-47-6 "KEGG COMPOUND";   CAS:57-64-7 "ChemIDplus";   DrugBank:DB00981;   Drug_Central:2159 "DrugCentral";   KEGG:C06535;   KEGG:D00196;   KNApSAcK:C00001757;   LINCS:LSM-2558
 xref_mesh: MESH:D010830


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physostigmine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadac arylacetamide deacetylase JBrowse link 2 150,146,234 150,157,480 RGD:6480464
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
G Chat choline O-acetyltransferase JBrowse link 16 8,576,858 8,686,131 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6480464
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6480464
G Slc18a3 solute carrier family 18 member A3 JBrowse link 16 8,682,668 8,685,529 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
physostigmine salicylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        pharmacological role 18671
          neurotransmitter agent 16221
            miotic 65
              physostigmine 20
                physostigmine salicylate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic ester 13946
                                        carbamate ester 7330
                                          physostigmine 20
                                            physostigmine salicylate 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.