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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoflavanone
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Accession:CHEBI:27945 term browser browse the term
Definition:Isoflavone in which the double bond between positions 2 and 3 has been reduced to a single bond.
Synonyms:exact_synonym: 3-phenyl-2,3-dihydro-4H-chromen-4-one
 related_synonym: 2,3-dihydro-3-phenyl-4H-1-benzopyran-4-one;   3-phenylchroman-4-one;   Formula=C15H12O2;   InChI=1S/C15H12O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-9,13H,10H2;   InChIKey=RTRZOHKLISMNRD-UHFFFAOYSA-N;   SMILES=O=C1C(COc2ccccc12)c1ccccc1
 alt_id: CHEBI:24890;   CHEBI:6012
 xref: Beilstein:1621056;   CAS:4737-27-3;   KEGG:C01927


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cajanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein CTD PMID:20638373 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO cajanol results in decreased expression of BCL2 protein
[[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein
CTD PMID:20638373 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein
cajanol results in increased activity of CASP3 protein
CTD PMID:20638373 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein
cajanol results in increased activity of CASP9 protein
CTD PMID:20638373 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO cajanol affects the localization of CYCS protein
[[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein
CTD PMID:20638373 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      group 19722
        inorganic group 19180
          oxo group 18427
            organic oxo compound 18427
              carbonyl compound 18427
                ketone 16171
                  cyclic ketone 13874
                    isoflavanones 184
                      isoflavanone 5
                        (3S)-isoflavanone + 5
                        2,6,7,4'-tetrahydroxyisoflavanone 0
                        ferreirin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  oxacycle 17200
                                    benzopyran 10149
                                      1-benzopyran 9865
                                        isoflavonoid 3806
                                          isoflavans 220
                                            isoflavanones 184
                                              isoflavanone 5
                                                (3S)-isoflavanone + 5
                                                2,6,7,4'-tetrahydroxyisoflavanone 0
                                                ferreirin 0
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