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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium azide
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Accession:CHEBI:278547 term browser browse the term
Definition:The sodium salt of hydrogen azide (hydrazoic acid).
Synonyms:related_synonym: Azoture de sodium;   Formula=N3Na;   InChI=1S/N3.Na/c1-3-2;/q-1;+1;   InChIKey=PXIPVTKHYLBLMZ-UHFFFAOYSA-N;   NaN3;   Natriumazid;   SMILES=[Na+].[N-]=[N+]=[N-];   hydrazoic acid sodium salt
 xref: CAS:26628-22-8
 xref_mesh: MESH:D019810
 xref: MetaCyc:CPD-23697;   PMID:25916484;   PMID:28712037;   PMID:28849152;   PMID:29947902;   PMID:30664159;   PMID:31088611;   PMID:31821925;   PMID:32437849;   PMID:32844280;   PMID:33400299;   Pesticides:sodium_azide;   Wikipedia:Sodium_azide


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sodium azide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]; Sodium Azide inhibits the reaction [ABCB1 protein results in increased export of Diazinon] CTD PMID:12526924 PMID:16221533 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]]; Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide] CTD PMID:10856430 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity		 EXP [bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased activity of ACHE protein]; [bergenin co-treated with Sodium Azide] results in increased activity of ACHE protein; [Donepezil co-treated with Sodium Azide] results in increased activity of ACHE protein CTD PMID:36249784 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression		 ISO
EXP		 [Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]
2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [bergenin affects the reaction [Sodium Azide results in increased expression of APP protein]]; bergenin affects the reaction [Sodium Azide results in increased expression of APP protein]		 CTD PMID:17405930 PMID:22906069 PMID:36249784 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions EXP Sodium Azide inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects localization		 EXP Minocycline inhibits the reaction [Sodium Azide affects the localization of BAX protein] CTD PMID:15004018 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Sodium Azide inhibits the reaction [Minocycline results in increased expression of BCL2 protein] CTD PMID:15004018 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP Minocycline inhibits the reaction [Sodium Azide results in increased activity of CASP3 protein] CTD PMID:15004018 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions		 ISO Sodium Azide results in decreased expression of CCNA2 mRNA; Sodium Azide results in decreased expression of CCNA2 protein
Sodium Azide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]		 CTD PMID:12730239 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression		 ISO Sodium Azide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
Sodium Azide results in decreased expression of CCNB1 mRNA; Sodium Azide results in decreased expression of CCNB1 protein		 CTD PMID:12730239 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of CDKN1A mRNA] CTD PMID:17045927 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Sodium Azide results in decreased expression of CIRBP mRNA CTD PMID:15075239 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Cp ceruloplasmin multiple interactions ISO Sodium Azide inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] CTD PMID:16756764 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Dao D-amino-acid oxidase decreases activity ISO Sodium Azide results in decreased activity of DAO protein CTD PMID:16846222 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO Sodium Azide inhibits the reaction [IFNG protein results in increased activity of DUOX2 protein] CTD PMID:16970942 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA] CTD PMID:10723097 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions
decreases localization		 ISO Sodium Azide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]; Sodium Azide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]
Sodium Azide results in decreased localization of ELAVL1 protein		 CTD PMID:12730239 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA] CTD PMID:10723097 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects expression EXP Sodium Azide affects the expression of HIF1A protein CTD PMID:16034640 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Sodium Azide inhibits the reaction [IFNG protein results in increased activity of DUOX2 protein] CTD PMID:16970942 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 EXP [bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased expression of IL1B protein]; [Sodium Azide co-treated with bergenin] results in increased expression of IL1B protein; [Sodium Azide co-treated with Donepezil] results in increased expression of IL1B protein CTD PMID:36249784 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Sodium Azide inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO Sodium Azide inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Sodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP1 protein]; Sodium Azide inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA] CTD PMID:10836612 PMID:12542540 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO Sodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP3 protein] CTD PMID:12542540 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity		 ISO
EXP		 Sodium Azide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; Sodium Azide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; Sodium Azide inhibits the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Azide inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]; Sodium Azide inhibits the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]
[bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased activity of MPO protein]; [Sodium Azide co-treated with bergenin] results in increased activity of MPO protein; [Sodium Azide co-treated with Donepezil] results in increased activity of MPO protein		 CTD PMID:19462961 PMID:22906169 PMID:25614581 PMID:36249784 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions ISO Sodium Azide inhibits the reaction [COX3 protein results in decreased susceptibility to Gemcitabine] CTD PMID:17428446 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of NOS3 mRNA]; Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of NOS3 protein] CTD PMID:17045927 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression EXP Sodium Azide results in decreased expression of PPP1CA protein CTD PMID:15113600 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Sodium Azide results in decreased expression of PPP1CC protein CTD PMID:15113600 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 increases response to substance ISO PPT1 protein results in increased susceptibility to Sodium Azide CTD PMID:27722792 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Sodium Azide results in increased phosphorylation of PRKAA1 protein CTD PMID:28298333 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Psen2 presenilin 2 decreases expression ISO Sodium Azide results in decreased expression of PSEN2 mRNA CTD PMID:12938025 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Rbm3 RNA binding motif protein 3 decreases expression ISO Sodium Azide results in decreased expression of RBM3 mRNA CTD PMID:15075239 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO Sodium Azide inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] CTD PMID:15804185 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Sodium Azide results in increased expression of SLC2A1 mRNA CTD PMID:14578187 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Sodium Azide results in increased expression of SLC2A4 mRNA CTD PMID:17957036 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP [bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased expression of TNF protein]; [Sodium Azide co-treated with bergenin] results in increased expression of TNF protein; [Sodium Azide co-treated with Donepezil] results in increased expression of TNF protein; Sodium Azide promotes the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein] CTD PMID:7539275 PMID:36249784 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA] CTD PMID:17045927 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpo thyroid peroxidase decreases activity EXP Sodium Azide results in decreased activity of TPO protein CTD PMID:26884060 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Txn2 thioredoxin 2 affects expression
multiple interactions		 ISO Sodium Azide affects the expression of TXN2 mRNA; Sodium Azide affects the expression of TXN2 protein
[Sodium Azide co-treated with Hydrogen Peroxide] affects the expression of TXN2 mRNA		 CTD PMID:15133893 PMID:17074421 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
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  CHEBI ontology 19811
    role 19818
      chemical role 19422
        explosive 4715
          sodium azide 41
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  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      s-block molecular entity 19628
                        alkali metal molecular entity 12797
                          sodium molecular entity 11287
                            elemental sodium 11287
                              sodium(1+) 11287
                                sodium salt 11287
                                  inorganic sodium salt 10997
                                    sodium azide 41
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