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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyanidin cation
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Accession:CHEBI:27843 term browser browse the term
Definition:An anthocyanidin cation that is flavylium substituted at positions 3, 3', 4', 5 and 7 by hydroxy groups.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenium
 related_synonym: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopyrylium;   2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenylium;   3,5,7,3',4'-Pentahydroxyflavylium;   Cyanidin;   Cyanidine;   Cyanidol;   Formula=C15H11O6;   InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6H,(H4-,16,17,18,19,20)/p+1;   InChIKey=VEVZSMAEJFVWIL-UHFFFAOYSA-O;   SMILES=Oc1cc(O)c2cc(O)c([o+]c2c1)-c1ccc(O)c(O)c1
 alt_id: CHEBI:23425;   CHEBI:3970
 xref: Beilstein:1690254;   CAS:13306-05-3;   KEGG:C05905;   KNApSAcK:C00006614;   LIPID_MAPS_instance:LMPK12010002
 xref_mesh: MESH:C017154
 xref: MetaCyc:CPD-591;   PMID:23123597;   PMID:23360684;   PMID:23375153;   PMID:23389674;   Reaxys:1690254;   Wikipedia:Cyanidin
 cyclic_relationship: is_conjugate_acid_of CHEBI:71682


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cyanidin cation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity ISO cyanidin results in increased activity of AHR protein CTD PMID:23419638 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein]
CTD PMID:32044269 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP
ISO
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CSF2 protein]
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]
CTD PMID:32044269 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO cyanidin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO cyanidin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmox1 heme oxygenase 1 affects expression ISO cyanidin affects the expression of HMOX1 protein CTD PMID:26505893 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]] CTD PMID:32044269 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein] CTD PMID:32044269 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of IL23A protein]
CTD PMID:32044269 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein] CTD PMID:32044269 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein] CTD PMID:32044269 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
affects expression
EXP
ISO
cyanidin results in increased activity of NFE2L2 protein
cyanidin affects the expression of NFE2L2 protein
CTD PMID:26505893 PMID:27166148 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO cyanidin results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein] CTD PMID:32044269 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein CTD PMID:32044269 NCBI chr 2:198,821,377...198,831,533
Ensembl chr 2:198,823,366...198,836,372
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein]
CTD PMID:32044269 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]
CTD PMID:32044269 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA] CTD PMID:28533128 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA] CTD PMID:28533128 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein]; cyanidin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] CTD PMID:16921400 PMID:26800359 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      chemical role 19260
        antioxidant 14254
          cyanidin cation 22
            6-hydroxycyanidin 0
            cyanidin 3,3',5-tri-O-glucoside 0
            cyanidin 3,7-di-O-beta-D-glucoside 0
            cyanidin 3,7-di-O-beta-D-glucoside betaine 0
            cyanidin 3-O-(2''-O-galloyl-beta-D-galactopyranoside) 0
            cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside 0
            cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine 0
            cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-) 0
            cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
            cyanidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
            cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) 0
            cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) 0
            cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) 0
            cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) 0
            cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] 0
            cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-) 0
            cyanidin 3-O-\ 0
            cyanidin 3-O-\ 0
            cyanidin 3-O-beta-D-galactoside + 0
            cyanidin 3-O-beta-D-galactoside betaine 0
            cyanidin 3-O-beta-D-glucoside 0
            cyanidin 3-O-beta-D-glucoside(1-) 0
            cyanidin 3-O-beta-D-sambubioside 0
            cyanidin 3-O-rutinoside + 0
            cyanidin 3-O-rutinoside 5-O-beta-D-glucoside 0
            cyanin + 0
            cyanin betaine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic molecule 19504
                              organic cyclic compound 19331
                                organic heterocyclic compound 18519
                                  oxacycle 17539
                                    benzopyran 10267
                                      1-benzopyran 9989
                                        chromenes 931
                                          chromene 132
                                            2H-chromene 132
                                              chromenyliums 132
                                                chromenylium 132
                                                  flavylium 132
                                                    anthocyanidin cation 132
                                                      5-hydroxyanthocyanidin 80
                                                        cyanidin cation 22
                                                          6-hydroxycyanidin 0
                                                          cyanidin 3,3',5-tri-O-glucoside 0
                                                          cyanidin 3,7-di-O-beta-D-glucoside 0
                                                          cyanidin 3,7-di-O-beta-D-glucoside betaine 0
                                                          cyanidin 3-O-(2''-O-galloyl-beta-D-galactopyranoside) 0
                                                          cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside 0
                                                          cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine 0
                                                          cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-) 0
                                                          cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
                                                          cyanidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
                                                          cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) 0
                                                          cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) 0
                                                          cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) 0
                                                          cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) 0
                                                          cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] 0
                                                          cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-) 0
                                                          cyanidin 3-O-\ 0
                                                          cyanidin 3-O-\ 0
                                                          cyanidin 3-O-beta-D-galactoside + 0
                                                          cyanidin 3-O-beta-D-galactoside betaine 0
                                                          cyanidin 3-O-beta-D-glucoside 0
                                                          cyanidin 3-O-beta-D-glucoside(1-) 0
                                                          cyanidin 3-O-beta-D-sambubioside 0
                                                          cyanidin 3-O-rutinoside + 0
                                                          cyanidin 3-O-rutinoside 5-O-beta-D-glucoside 0
                                                          cyanin + 0
                                                          cyanin betaine 0
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