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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:apocynin
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Accession:CHEBI:2781 term browser browse the term
Definition:An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Synonyms:exact_synonym: 1-(4-hydroxy-3-methoxyphenyl)ethan-1-one
 related_synonym: 1-(4-Hydroxy-3-methoxyphenyl)ethanone;   4'-hydroxy-3'-methoxyacetophenone;   4-Acetyl-2-methoxyphenol;   4-Hydroxy-3-methoxyphenyl methyl ketone;   Acetoguaiacon;   Acetoguaiacone;   Acetovanillone;   Formula=C9H10O3;   InChI=1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3;   InChIKey=DFYRUELUNQRZTB-UHFFFAOYSA-N;   SMILES=COC1=C(O)C=CC(=C1)C(C)=O
 xref: Beilstein:637373;   CAS:498-02-2;   KEGG:C11380;   KNApSAcK:C00002689
 xref_mesh: MESH:C056165
 xref: PDBeChem:I75;   PMID:21848266;   PMID:21954959;   PMID:24870309;   Reaxys:637373;   Wikipedia:Apocynin


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apocynin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] CTD PMID:18474546 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO acetovanillone inhibits the reaction [Mitogens results in increased expression of ACTA2 protein] CTD PMID:29760339 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G AGT angiotensinogen multiple interactions
decreases activity		 EXP
ISO		 [acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein; acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]
acetovanillone results in decreased activity of AGT protein
acetovanillone inhibits the reaction [AGT protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [AGT protein results in increased activity of PARP1 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
acetovanillone inhibits the reaction [AGT protein results in decreased export of Sodium]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Oxygen]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]; acetovanillone inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]		 CTD PMID:14597645 PMID:15502880 PMID:15677497 PMID:16531806 PMID:17224469 More... NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein]; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein] CTD PMID:28202386 PMID:30366073 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B multiple interactions EXP acetovanillone inhibits the reaction [Uric Acid results in increased expression of AKR1B1 mRNA] CTD PMID:30651350 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:26514923 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALB albumin multiple interactions ISO acetovanillone inhibits the reaction [Mitogens results in decreased expression of ALB protein] CTD PMID:29760339 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions ISO acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] CTD PMID:24080574 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions EXP acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of ATF2 protein] CTD PMID:22288910 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]		 CTD PMID:22431579 PMID:29859868 PMID:30366073 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of BCL2 protein]; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein]		 CTD PMID:22431579 PMID:29859868 PMID:30366073 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein] CTD PMID:30366073 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BECN1 beclin 1 multiple interactions ISO acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of BECN1 protein] CTD PMID:29859868 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA] CTD PMID:24080574 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G CASP1 caspase 1 multiple interactions EXP acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form] CTD PMID:26079697 PMID:26901245 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP		 acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; acetovanillone inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CASP3 protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]
[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased cleavage of CASP3 mRNA]		 CTD PMID:20153346 PMID:22147442 PMID:22497828 PMID:24291008 PMID:26522475 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions ISO [acetovanillone co-treated with CAT protein] inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; [acetovanillone results in increased susceptibility to Thioctic Acid] inhibits the reaction [Mitogens results in decreased activity of CAT protein]; acetovanillone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of CAT mRNA]; acetovanillone inhibits the reaction [Mitogens results in decreased activity of CAT protein]; acetovanillone inhibits the reaction [Pyrogallol results in increased activity of CAT protein]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in decreased activity of CAT protein]] CTD PMID:21983654 PMID:24291008 PMID:29760339 PMID:32298299 PMID:35944648 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA] CTD PMID:22414048 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL18 C-C motif chemokine ligand 18 multiple interactions EXP acetovanillone inhibits the reaction [arsenic trioxide results in increased secretion of CCL18 protein] CTD PMID:18424721 NCBI chr17:36,064,272...36,072,032
Ensembl chr17:36,064,272...36,072,032 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP acetovanillone inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; acetovanillone inhibits the reaction [Homocysteine results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 protein] CTD PMID:16845898 PMID:19158351 PMID:22414048 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]		 CTD PMID:10495789 PMID:22414048 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA] CTD PMID:22414048 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions EXP acetovanillone inhibits the reaction [[Oxygen deficiency results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD36 mRNA] CTD PMID:19640849 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CDH3 cadherin 3 multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in decreased expression of CDH3 protein] CTD PMID:21647593 NCBI chr16:68,645,310...68,733,771
Ensembl chr16:68,636,189...68,727,468 		JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions ISO acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein] CTD PMID:16531806 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]; acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein] CTD PMID:16531806 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO acetovanillone inhibits the reaction [Antimycin A results in decreased phosphorylation of CREB1 protein] CTD PMID:21538410 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA] CTD PMID:22414048 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CTF1 cardiotrophin 1 multiple interactions ISO acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of CTF1 protein]; acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein] CTD PMID:16507596 NCBI chr16:30,895,846...30,903,560
Ensembl chr16:30,896,614...30,903,547 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:22414048 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA]; acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA] CTD PMID:18322232 PMID:22414048 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP acetovanillone inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein] CTD PMID:20920494 PMID:22414048 PMID:27393034 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain multiple interactions ISO acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]		 CTD PMID:23270704 PMID:29037473 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB mRNA]; acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of CYBB protein]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]		 CTD PMID:19878672 PMID:23270704 PMID:24080574 PMID:30797899 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of CYCS protein] CTD PMID:36988283 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G DES desmin multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES mRNA]; acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES protein] CTD PMID:20036696 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DMD dystrophin multiple interactions ISO acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA] CTD PMID:26930420 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609 		JBrowse link
G EDN1 endothelin 1 multiple interactions ISO [polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein]; acetovanillone inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]; acetovanillone inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species]
acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]		 CTD PMID:17391658 PMID:20977430 PMID:22431579 PMID:24932781 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA protein] CTD PMID:23270704 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein] CTD PMID:23270704 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]] CTD PMID:19281832 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha multiple interactions ISO acetovanillone inhibits the reaction [arsenite results in increased expression of ERO1A protein] CTD PMID:37659621 NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions ISO acetovanillone inhibits the reaction [Gentamicins results in increased expression of FAS protein] CTD PMID:28116922 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FN1 fibronectin 1 multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]
acetovanillone inhibits the reaction [Glucose results in increased expression of FN1 protein]		 CTD PMID:15086456 PMID:16632126 PMID:22245600 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of FSHB protein] CTD PMID:23270704 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GAD1 glutamate decarboxylase 1 multiple interactions ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151 		JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of GFAP protein] CTD PMID:30797899 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 protein] CTD PMID:23270704 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GLO1 glyoxalase I multiple interactions ISO acetovanillone inhibits the reaction [Pyruvaldehyde results in decreased activity of GLO1 protein] CTD PMID:25042521 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145 		JBrowse link
G GNA11 G protein subunit alpha 11 multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in increased expression of GNA11 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr19:3,094,362...3,123,999
Ensembl chr19:3,094,362...3,123,999 		JBrowse link
G GNAQ G protein subunit alpha q multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 9:77,716,097...78,031,811
Ensembl chr 9:77,716,097...78,031,811 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]; acetovanillone inhibits the reaction [Pyrogallol results in increased activity of GPX1 protein]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]		 CTD PMID:22431579 PMID:29037473 PMID:35944648 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 multiple interactions ISO acetovanillone inhibits the reaction [Formaldehyde results in increased expression of GPX3 mRNA] CTD PMID:21983654 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein] CTD PMID:30797899 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GSDMD gasdermin D multiple interactions EXP acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein] CTD PMID:30378427 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 increases expression ISO acetovanillone results in increased expression of GUCY1A1 protein CTD PMID:25217652 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO acetovanillone results in increased expression of GUCY1B1 protein CTD PMID:25217652 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G GYPA glycophorin A (MNS blood group) multiple interactions EXP acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] CTD PMID:20523355 NCBI chr 4:144,109,303...144,140,718
Ensembl chr 4:144,109,303...144,140,751 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO
EXP		 acetovanillone results in increased expression of HIF1A protein
acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]		 CTD PMID:12595275 PMID:23144690 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMGB1 high mobility group box 1 multiple interactions EXP acetovanillone inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein] CTD PMID:26079697 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
decreases expression		 EXP
ISO		 acetovanillone inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; acetovanillone inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; acetovanillone inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]
acetovanillone inhibits the reaction [Cisplatin results in increased expression of HMOX1 mRNA]
acetovanillone results in decreased expression of HMOX1 mRNA		 CTD PMID:19414066 PMID:20934533 PMID:21690482 PMID:24291008 PMID:26945724 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein] CTD PMID:30366073 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G HTRA2 HtrA serine peptidase 2 multiple interactions EXP [tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione affects the localization of HTRA2 protein] CTD PMID:20153346 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
decreases expression		 EXP
ISO		 acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
acetovanillone results in decreased expression of ICAM1 protein		 CTD PMID:10495789 PMID:19417757 PMID:19632255 PMID:20920494 PMID:22414048 More... NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNB1 interferon beta 1 multiple interactions EXP acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of IFNB1 mRNA] CTD PMID:18322232 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNG interferon gamma multiple interactions ISO acetovanillone results in decreased susceptibility to [IFNG protein co-treated with Lipopolysaccharides]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IFNG protein]		 CTD PMID:16307444 PMID:30366073 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases response to substance		 ISO
EXP		 acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]; acetovanillone inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of IL1B protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
acetovanillone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; acetovanillone inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]
acetovanillone results in decreased susceptibility to IL1B protein
acetovanillone inhibits the reaction [Ethanol results in increased expression of IL1B protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL1B protein]		 CTD PMID:18403674 PMID:19005069 PMID:19281832 PMID:21211511 PMID:21983654 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [Pyruvaldehyde results in increased expression of IL6 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 protein]
acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [Pyrogallol results in increased expression of IL6 protein]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of IL6 protein]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of IL6 protein]]		 CTD PMID:21983654 PMID:22414048 PMID:22472292 PMID:24631921 PMID:25042521 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO acetovanillone inhibits the reaction [Mitogens results in increased secretion of INS1 protein]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased secretion of INS1 protein]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased secretion of INS1 protein]] CTD PMID:29760339 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G ITGA2B integrin subunit alpha 2b multiple interactions EXP acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] CTD PMID:20523355 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGAM integrin subunit alpha M multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of ITGAM mRNA]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ITGAM protein]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ITGAM protein]		 CTD PMID:16357311 PMID:28202386 PMID:30797899 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB3 integrin subunit beta 3 multiple interactions EXP acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] CTD PMID:20523355 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions EXP acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of and results in increased expression of JUN protein]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of JUN mRNA]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of JUN protein] CTD PMID:22288910 PMID:36988283 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G LEP leptin multiple interactions ISO acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; acetovanillone inhibits the reaction [LEP protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF1 protein]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein] CTD PMID:16380530 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor multiple interactions ISO acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; acetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides] CTD PMID:19478208 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of LHB protein] CTD PMID:23270704 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LPO lactoperoxidase multiple interactions ISO acetovanillone inhibits the reaction [Pyrogallol results in increased activity of LPO protein] CTD PMID:35944648 NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions ISO acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased lipidation of MAP1LC3B protein] CTD PMID:29859868 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]		 CTD PMID:16632126 PMID:20354174 PMID:21391979 PMID:22288910 PMID:23774252 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:16632126 PMID:20354174 PMID:21391979 PMID:22288910 PMID:23774252 More... NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]
acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein]		 CTD PMID:20354174 PMID:21391979 PMID:24967690 PMID:26514923 PMID:36988283 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK9 protein]; acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] CTD PMID:21391979 PMID:24967690 PMID:26514923 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MIF macrophage migration inhibitory factor multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of MIF mRNA] CTD PMID:22414048 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase multiple interactions EXP acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of MLKL protein] CTD PMID:30378427 NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions EXP acetovanillone inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP13 protein] CTD PMID:21211511 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 protein]; acetovanillone inhibits the reaction [RELA protein binds to MMP9 promoter]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]		 CTD PMID:23270704 PMID:23774252 PMID:26514923 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase decreases expression
multiple interactions		 ISO acetovanillone results in decreased expression of MPO protein
acetovanillone inhibits the reaction [Cisplatin results in increased activity of MPO protein]		 CTD PMID:19417757 PMID:24291008 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MSR1 macrophage scavenger receptor 1 multiple interactions EXP acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein]; acetovanillone inhibits the reaction [Arsenic Trioxide affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of NCF1 protein]; acetovanillone inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides affects the localization of NCF1 protein]; acetovanillone inhibits the reaction [N-Methylaspartate affects the localization of NCF1 protein]
acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 mRNA]; acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF1 protein]		 CTD PMID:16380530 PMID:18424721 PMID:19281832 PMID:19878672 PMID:20299304 More... NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 multiple interactions ISO acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]		 CTD PMID:16380530 PMID:24080574 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 multiple interactions EXP acetovanillone inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which affects the localization of NFATC1 protein] CTD PMID:22564430 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [Cisplatin results in increased expression of NFE2L2 mRNA]
[acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein		 CTD PMID:24291008 PMID:27983965 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [Homocysteine results in increased phosphorylation of and results in increased activity of NFKBIA protein]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; acetovanillone inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]		 CTD PMID:16845898 PMID:17065336 PMID:28202386 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein] CTD PMID:26901245 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO acetovanillone inhibits the reaction [Ethanol results in increased expression of NOS2 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS2 mRNA]
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]		 CTD PMID:21983654 PMID:26522475 PMID:28202386 PMID:30797899 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases expression		 EXP
ISO		 acetovanillone inhibits the reaction [Glucose results in decreased expression of NOS3 protein]
[Cadmium co-treated with acetovanillone] results in increased expression of NOS3 protein; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS3 mRNA]
acetovanillone results in increased expression of NOS3 protein		 CTD PMID:19878672 PMID:21983654 PMID:23703608 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOX1 NADPH oxidase 1 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX1 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX1 mRNA]]
acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX1 mRNA]		 CTD PMID:26522475 PMID:29760339 PMID:30797899 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NOX4 NADPH oxidase 4 multiple interactions ISO
EXP		 [acetovanillone co-treated with CAT protein] inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; acetovanillone inhibits the reaction [Cyclosporine results in increased expression of NOX4 mRNA]; acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX4 protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of NOX4 mRNA]]
acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of NOX4 mRNA]; acetovanillone inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of NOX4 protein]		 CTD PMID:26522475 PMID:29760339 PMID:32298299 PMID:36988283 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NOXA1 NADPH oxidase activator 1 multiple interactions ISO acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA] CTD PMID:24080574 NCBI chr 9:137,423,393...137,434,406
Ensembl chr 9:137,423,350...137,434,406 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 multiple interactions ISO acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA] CTD PMID:24080574 NCBI chr16:1,978,917...1,981,469
Ensembl chr16:1,978,917...1,984,192 		JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS1 mRNA]; acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS1 protein] CTD PMID:20036696 NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287 		JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein] CTD PMID:20036696 NCBI chr 1:179,550,539...179,575,948
Ensembl chr 1:179,550,539...179,575,952 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 multiple interactions EXP acetovanillone inhibits the reaction [Glucose results in increased expression of OLR1 mRNA] CTD PMID:19878672 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [AGT protein results in increased activity of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]
[polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein]
acetovanillone inhibits the reaction [arsenite results in increased oxidation of PARP1 protein]; acetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]		 CTD PMID:15502880 PMID:18509044 PMID:24932781 PMID:29111459 PMID:34798142 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO acetovanillone inhibits the reaction [Ozone results in increased expression of PCNA protein] CTD PMID:9517619 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PLCB1 phospholipase C beta 1 multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB1 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] CTD PMID:20691780 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360 		JBrowse link
G PLCB2 phospholipase C beta 2 multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] CTD PMID:20691780 NCBI chr15:40,284,256...40,307,935
Ensembl chr15:40,278,176...40,307,935 		JBrowse link
G POMC proopiomelanocortin multiple interactions ISO acetovanillone inhibits the reaction [POMC protein affects the abundance of F2-Isoprostanes] CTD PMID:16053986 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PRKCD protein kinase C delta multiple interactions ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased cleavage of PRKCD protein]		 CTD PMID:29859868 PMID:30366073 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 multiple interactions ISO acetovanillone inhibits the reaction [Glucose results in decreased expression of PRKG1 protein] CTD PMID:17320767 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO acetovanillone inhibits the reaction [Formaldehyde results in increased expression of PTGS1 mRNA]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] CTD PMID:18414395 PMID:21983654 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO
EXP		 acetovanillone inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; acetovanillone inhibits the reaction [Pyrogallol results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
acetovanillone inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; acetovanillone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein]
acetovanillone results in decreased expression of PTGS2 mRNA		 CTD PMID:17244722 PMID:18414395 PMID:21983654 PMID:22288910 PMID:23415682 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta multiple interactions ISO acetovanillone inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein] CTD PMID:23774252 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G PVALB parvalbumin multiple interactions ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein] CTD PMID:18063801 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions EXP acetovanillone inhibits the reaction [Ethanol results in increased expression of PYCARD protein] CTD PMID:26079697 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of RELA protein]; acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]; acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]
acetovanillone inhibits the reaction [RELA protein binds to MMP9 promoter]; acetovanillone inhibits the reaction [TNF protein affects the localization of RELA protein]		 CTD PMID:19281832 PMID:19608869 PMID:20354174 PMID:23774252 PMID:26930420 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA] CTD PMID:24080574 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G S100A4 S100 calcium binding protein A4 multiple interactions ISO acetovanillone inhibits the reaction [Homocysteine results in increased expression of S100A4 protein] CTD PMID:21647593 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G SELE selectin E multiple interactions EXP acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein] CTD PMID:26901245 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions EXP acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:22414048 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SHC1 SHC adaptor protein 1 multiple interactions ISO acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 protein] CTD PMID:23270704 NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA] CTD PMID:26930420 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 multiple interactions ISO acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of SLC40A1 protein] CTD PMID:30797899 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758 		JBrowse link
G SNCA synuclein alpha multiple interactions ISO acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased phosphorylation of SNCA protein] CTD PMID:29859868 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD1 mRNA]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]		 CTD PMID:21983654 PMID:22431579 PMID:29037473 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD2 mRNA]
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]		 CTD PMID:21983654 PMID:22431579 PMID:29037473 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO acetovanillone inhibits the reaction [Hydrogen Peroxide deficiency results in decreased expression of STAR protein]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR mRNA]; acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR protein] CTD PMID:23270704 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [vanadium pentoxide results in increased phosphorylation of STAT1 protein]
acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of and results in increased phosphorylation of STAT1 protein]		 CTD PMID:18322232 PMID:29859868 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO acetovanillone inhibits the reaction [Mitogens results in increased expression of TGFB1 protein] CTD PMID:29760339 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TH tyrosine hydroxylase decreases expression
multiple interactions		 ISO acetovanillone results in decreased expression of TH mRNA
acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein]		 CTD PMID:25217652 PMID:29859868 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP
ISO		 acetovanillone inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of TJP1 protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]
acetovanillone inhibits the reaction [Homocysteine results in decreased expression of TJP1 protein]		 CTD PMID:20299304 PMID:21647593 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases response to substance		 EXP
ISO		 acetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Superoxides]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MIF mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
acetovanillone inhibits the reaction [Cisplatin results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Ethanol results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Mitogens results in increased expression of TNF protein]; acetovanillone inhibits the reaction [TNF protein affects the localization of RELA protein]; acetovanillone inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein]; acetovanillone inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; acetovanillone promotes the reaction [Thioctic Acid inhibits the reaction [Mitogens results in increased expression of TNF protein]]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in increased expression of TNF protein]]
acetovanillone results in decreased susceptibility to TNF protein
acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; acetovanillone inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein]; acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; acetovanillone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]		 CTD PMID:10495789 PMID:15795323 PMID:16632126 PMID:19608869 PMID:21211511 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein] CTD PMID:22431579 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions ISO Apocynin inhibits the reaction [hydrogen peroxide increases expression of Traf6 protein in rat neonatal cardiomyocytes] RGD PMID:27249171 RGD:155646134 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein] CTD PMID:19281832 PMID:19632255 PMID:26901245 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO acetovanillone inhibits the reaction [Cocaine results in increased activity of XDH protein] CTD PMID:17217956 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        anti-inflammatory agent 17787
          anti-inflammatory drug 15742
            non-steroidal anti-inflammatory drug 15003
              apocynin 138
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            heteroorganic entity 24766
                              organochalcogen compound 24378
                                organooxygen compound 24054
                                  carbonyl compound 23563
                                    ketone 19347
                                      methyl ketone 820
                                        acetophenones 162
                                          apocynin 138
paths to the root