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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimethobenzamide
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Accession:CHEBI:27796 term browser browse the term
Definition:The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
Synonyms:exact_synonym: N-{4-[2-(dimethylamino)ethoxy]benzyl}-3,4,5-trimethoxybenzamide
 related_synonym: Formula=C21H28N2O5;   InChI=1S/C21H28N2O5/c1-23(2)10-11-28-17-8-6-15(7-9-17)14-22-21(24)16-12-18(25-3)20(27-5)19(13-16)26-4/h6-9,12-13H,10-11,14H2,1-5H3,(H,22,24);   InChIKey=FEZBIKUBAYAZIU-UHFFFAOYSA-N;   N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide;   SMILES=COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1;   trimethobenzamidum;   trimetobenzamida
 alt_id: CHEBI:27123;   CHEBI:9730
 xref: Beilstein:2186451;   CAS:138-56-7;   DrugBank:DB00662;   Drug_Central:2754;   KEGG:C07178;   KEGG:D08643;   LINCS:LSM-2750
 xref_mesh: MESH:C100146
 xref: Wikipedia:Trimethobenzamide


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trimethobenzamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO trimethobenzamide results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pharmaceutical 20416
          drug 20416
            antiemetic 5409
              trimethobenzamide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      carboacyl group 18085
                                        univalent carboacyl group 18085
                                          carbamoyl group 17921
                                            carboxamide 17921
                                              monocarboxylic acid amide 15953
                                                arenecarboxamide 8285
                                                  benzamides 8285
                                                    trimethobenzamide 1
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