Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:griseofulvin
go back to main search page
Accession:CHEBI:27779 term browser browse the term
Definition:An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.
Synonyms:exact_synonym: (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
 related_synonym: Curling factor;   Formula=C17H17ClO6;   Fulcin;   Fulvicin;   Grifulvin;   Grisactin;   Grisovin;   Grysio;   InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1;   InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N;   Lamoryl;   Likuden;   Poncyl;   SMILES=COc1cc(OC)c2C(=O)[C@]3(Oc2c1Cl)[C@H](C)CC(=O)C=C3OC;   Spirofulvin;   Sporostatin;   amudane;   griseofulvina;   griseofulvine;   griseofulvinum
 alt_id: CHEBI:24429;   CHEBI:5546
 xref: Beilstein:95226;   CAS:126-07-8;   DrugBank:DB00400;   Drug_Central:1331;   KEGG:C06686;   KEGG:D00209;   KNApSAcK:C00002398;   LINCS:LSM-5259;   LIPID_MAPS_instance:LMPK13060001
 xref_mesh: MESH:D006118
 xref: MetaCyc:CPD-17786;   PMID:14407521;   PMID:15078340;   PMID:16922553;   PMID:23111828;   PMID:25476923;   PMID:3277037;   PPDB:1807;   Patent:US3069328;   Patent:US3069329;   Reaxys:95226;   VSDB:1807;   Wikipedia:Griseofulvin


show annotations for term's descendants           Sort by:
 
griseofulvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Griseofulvin results in increased expression of ABCB1A mRNA CTD PMID:8707270 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Griseofulvin results in increased expression of ABCB4 mRNA CTD PMID:8707270 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression EXP
ISO
Griseofulvin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Griseofulvin results in decreased expression of ADRB3 mRNA CTD PMID:12735108 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 affects expression
multiple interactions
increases activity
increases expression
ISO Griseofulvin affects the expression of ALAS1 mRNA
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; [Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Melatonin inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]
Griseofulvin results in increased expression of ALAS1 mRNA
CTD PMID:10215191 PMID:12735108 PMID:15793285 PMID:24523661 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Anxa2 annexin A2 increases expression ISO Griseofulvin results in increased expression of ANXA2 mRNA CTD PMID:12735108 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa3 annexin A3 affects expression ISO Griseofulvin affects the expression of ANXA3 mRNA CTD PMID:12735108 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa5 annexin A5 increases expression ISO Griseofulvin results in increased expression of ANXA5 mRNA CTD PMID:12735108 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa6 annexin A6 increases expression ISO Griseofulvin results in increased expression of ANXA6 mRNA CTD PMID:12735108 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Areg amphiregulin increases expression ISO Griseofulvin results in increased expression of AREG protein CTD PMID:19267999 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Btc betacellulin increases expression ISO Griseofulvin results in increased expression of BTC protein CTD PMID:19267999 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
ISO Griseofulvin results in increased activity of CASP3 protein
Griseofulvin results in increased cleavage of CASP3 protein
CTD PMID:23329179 PMID:25412316 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO Griseofulvin results in increased activity of CASP9 protein CTD PMID:23329179 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Griseofulvin affects the expression of CBR1 mRNA CTD PMID:12735108 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cd14 CD14 molecule affects expression ISO Griseofulvin affects the expression of CD14 mRNA CTD PMID:12735108 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd24 CD24 molecule affects expression ISO Griseofulvin affects the expression of CD24A mRNA CTD PMID:12735108 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL1A1 mRNA CTD PMID:12735108 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL3A1 mRNA CTD PMID:12735108 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a1 collagen type IV alpha 1 chain affects expression ISO Griseofulvin affects the expression of COL4A1 mRNA CTD PMID:12735108 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cstb cystatin B increases expression ISO Griseofulvin results in increased expression of CSTB mRNA CTD PMID:12735108 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
multiple interactions
ISO Griseofulvin affects the expression of CYP1A2 mRNA
Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]
CTD PMID:9029748 PMID:12735108 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases activity
increases expression
ISO Griseofulvin results in increased activity of CYP2A5 protein
Griseofulvin results in increased expression of CYP2A5 mRNA; Griseofulvin results in increased expression of CYP2A5 protein
CTD PMID:7543189 PMID:9007836 PMID:9698299 PMID:11038160 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects expression ISO Griseofulvin affects the expression of CYP2B10 mRNA CTD PMID:12735108 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression ISO Griseofulvin affects the expression of CYP2B13 mRNA CTD PMID:12735108 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression ISO Griseofulvin affects the expression of CYP2B9 mRNA CTD PMID:12735108 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects expression ISO Griseofulvin affects the expression of CYP2C29 mRNA CTD PMID:12735108
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Griseofulvin results in increased expression of CYP3A4 mRNA; Griseofulvin results in increased expression of CYP3A4 protein CTD PMID:18505790 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Griseofulvin results in decreased expression of CYP7B1 mRNA CTD PMID:12735108 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Eln elastin affects expression ISO Griseofulvin affects the expression of ELN mRNA CTD PMID:12735108 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Ereg epiregulin increases expression ISO Griseofulvin results in increased expression of EREG protein CTD PMID:19267999 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Griseofulvin results in decreased expression of FABP1 mRNA CTD PMID:12735108 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fech ferrochelatase decreases activity
increases expression
multiple interactions
ISO Griseofulvin results in decreased activity of FECH protein
Griseofulvin results in increased expression of FECH mRNA
[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron; heme arginate inhibits the reaction [[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron]
CTD PMID:10215191 PMID:15078340 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fstl1 follistatin-like 1 affects expression ISO Griseofulvin affects the expression of FSTL1 mRNA CTD PMID:12735108 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO Griseofulvin results in decreased expression of G0S2 mRNA CTD PMID:12735108 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta affects expression ISO Griseofulvin affects the expression of GADD45B mRNA CTD PMID:12735108 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO Griseofulvin results in increased expression of and results in increased localization of GJA1 protein
Griseofulvin results in increased expression of GJA1 mRNA
CTD PMID:23329179 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects expression ISO Griseofulvin affects the expression of GSTM2 mRNA CTD PMID:12735108 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Hmox1 heme oxygenase 1 increases activity
increases expression
ISO Griseofulvin results in increased activity of HMOX1 protein
Griseofulvin results in increased expression of HMOX1 mRNA; Griseofulvin results in increased expression of HMOX1 protein
CTD PMID:10215191 PMID:15793285 PMID:16309571 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ier3 immediate early response 3 affects expression ISO Griseofulvin affects the expression of IER3 mRNA CTD PMID:12735108 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Griseofulvin results in decreased expression of IGF1 mRNA CTD PMID:12735108 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO Griseofulvin results in decreased expression of IGFALS mRNA CTD PMID:12735108 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Griseofulvin affects the expression of IGFBP2 mRNA CTD PMID:12735108 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein] CTD PMID:11367519 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Inhbc inhibin subunit beta C decreases expression ISO Griseofulvin results in decreased expression of INHBC mRNA CTD PMID:12735108 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 affects expression ISO Griseofulvin affects the expression of IQGAP1 mRNA CTD PMID:12735108 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Itgb2 integrin subunit beta 2 affects expression ISO Griseofulvin affects the expression of ITGB2 mRNA CTD PMID:12735108 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Krt18 keratin 18 multiple interactions
increases expression
decreases response to substance
ISO Griseofulvin promotes the reaction [KRT18 protein binds to KRT18 protein]
Griseofulvin results in increased expression of KRT18 mRNA; Griseofulvin results in increased expression of KRT18 protein
KRT18 protein results in decreased susceptibility to Griseofulvin
CTD PMID:7504119 PMID:8770877 PMID:10952237 PMID:12388748 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 increases expression
increases phosphorylation
ISO Griseofulvin results in increased expression of KRT8 mRNA; Griseofulvin results in increased expression of KRT8 protein
Griseofulvin results in increased phosphorylation of KRT8 protein
CTD PMID:7504119 PMID:10952237 PMID:12735108 PMID:20643122 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Griseofulvin results in decreased expression of LAMB1 protein CTD PMID:1573853 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamb2 laminin subunit beta 2 decreases expression
increases expression
ISO Griseofulvin results in decreased expression of LAMB2 protein
Griseofulvin results in increased expression of LAMB2 mRNA
CTD PMID:1573853 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 affects expression ISO Griseofulvin affects the expression of LILRB4 mRNA CTD PMID:12735108 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Lpl lipoprotein lipase affects expression ISO Griseofulvin affects the expression of LPL mRNA CTD PMID:12735108 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Griseofulvin results in increased expression of LY6D mRNA CTD PMID:12735108 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Griseofulvin results in increased expression of MAPT mRNA; Griseofulvin results in increased expression of MAPT mRNA alternative form; Griseofulvin results in increased expression of MAPT protein CTD PMID:10051481 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Griseofulvin results in increased expression of MT1 mRNA CTD PMID:12735108 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 affects expression ISO Griseofulvin affects the expression of NPDC1 mRNA CTD PMID:12735108 NCBI chr 3:8,220,446...8,226,446 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Griseofulvin results in increased expression of NQO1 mRNA CTD PMID:12735108 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Griseofulvin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 affects expression ISO Griseofulvin affects the expression of PAPSS2 mRNA CTD PMID:12735108 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
JBrowse link
G Pf4 platelet factor 4 affects expression ISO Griseofulvin affects the expression of PF4 mRNA CTD PMID:12735108 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Por cytochrome p450 oxidoreductase affects expression ISO Griseofulvin affects the expression of POR mRNA CTD PMID:12735108 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Griseofulvin results in decreased expression of PPARA mRNA CTD PMID:9548566 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Griseofulvin results in increased expression of PPARD mRNA CTD PMID:9548566 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Griseofulvin results in increased expression of PPARG mRNA CTD PMID:9548566 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppl periplakin affects expression ISO Griseofulvin affects the expression of PPL mRNA CTD PMID:12735108 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Griseofulvin results in increased expression of RARA mRNA CTD PMID:9548566 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Griseofulvin results in increased expression of RARB mRNA CTD PMID:9548566 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Griseofulvin results in increased expression of RARG mRNA CTD PMID:9548566 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Griseofulvin results in decreased expression of RXRA mRNA CTD PMID:9548566 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression ISO Griseofulvin results in decreased expression of RXRG mRNA CTD PMID:9548566 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO Griseofulvin results in increased expression of S100A6 mRNA CTD PMID:12735108 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 affects expression ISO Griseofulvin affects the expression of SCD2 mRNA CTD PMID:12735108 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Sele selectin E multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:11367519 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sell selectin L decreases expression ISO Griseofulvin results in decreased expression of SELL protein CTD PMID:11367519 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Soat1 sterol O-acyltransferase 1 affects expression ISO Griseofulvin affects the expression of SOAT1 mRNA CTD PMID:12735108 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression ISO Griseofulvin affects the expression of SPP1 mRNA CTD PMID:12735108 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tgm2 transglutaminase 2 affects expression ISO Griseofulvin affects the expression of TGM2 mRNA CTD PMID:12735108 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 affects expression ISO Griseofulvin affects the expression of TM4SF4 mRNA CTD PMID:12735108 NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200
JBrowse link
G Tmsb10 thymosin, beta 10 affects expression ISO Griseofulvin affects the expression of TMSB10 mRNA CTD PMID:12735108 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tmsb4x thymosin beta 4, X-linked affects expression ISO Griseofulvin affects the expression of TMSB4X mRNA CTD PMID:12735108 NCBI chr  X:27,144,677...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]] CTD PMID:11154858 PMID:11367519 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO Griseofulvin affects the expression of UGDH mRNA CTD PMID:12735108 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression ISO Griseofulvin affects the expression of UGT1A1 mRNA CTD PMID:12735108 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 affects expression
multiple interactions
ISO Griseofulvin affects the expression of VCAM1 mRNA
Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]
CTD PMID:11154858 PMID:11367519 PMID:12735108 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcl vinculin affects localization ISO Griseofulvin affects the localization of VCL protein CTD PMID:25412316 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Wnt3a Wnt family member 3A affects expression ISO Griseofulvin affects the expression of WNT3A mRNA CTD PMID:12735108 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Ybx3 Y box binding protein 3 affects expression ISO Griseofulvin affects the expression of YBX3 mRNA CTD PMID:12735108 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        antimicrobial agent 17408
          antibacterial agent 13571
            griseofulvin 87
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  oxacycle 17587
                                    benzofurans 3224
                                      1-benzofurans 1355
                                        griseofulvin 87
paths to the root