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Accession:CHEBI:27701 term browser browse the term
Definition:A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.
Synonyms:exact_synonym: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
 related_synonym: 5-Hydroxytetracycline;   Formula=C22H24N2O9;   InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1;   InChIKey=IWVCMVBTMGNXQD-PXOLEDIWSA-N;   Oxyterracin;   Oxyterracine;   Oxytetracyclin;   Oxytetracycline amphoteric;   Oxytetracycline anhydrous;   SMILES=[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C;   oxitetraciclina;   oxytetracyclinum
 alt_id: CHEBI:25811;   CHEBI:521157;   CHEBI:596903;   CHEBI:7871
 xref: BPDB:503;   Beilstein:2686362 "Beilstein";   Beilstein:2714587 "Beilstein";   CAS:79-57-2 "ChemIDplus";   CAS:79-57-2 "KEGG COMPOUND";   DrugBank:DB00595;   Drug_Central:2041 "DrugCentral";   Gmelin:623487 "Gmelin";   HMDB:HMDB0014733;   KEGG:C06624;   KNApSAcK:C00017127;   LIPID_MAPS_instance:LMPK07000005 "LIPID MAPS"
 xref_mesh: MESH:D010118
 xref: PMID:1650428 "Europe PMC";   PMID:17386724 "Europe PMC";   PMID:17638695 "ChEMBL";   PMID:17870541 "ChEMBL";   PMID:1833366 "Europe PMC";   PMID:21136283 "Europe PMC";   PMID:21488905 "Europe PMC";   PMID:22013404 "Europe PMC";   PMID:24247133 "Europe PMC";   PMID:24281679 "Europe PMC";   PMID:24290103 "Europe PMC";   PMID:24362004 "Europe PMC";   PMID:24510709 "Europe PMC";   PMID:24607684 "Europe PMC";   PMID:24853528 "Europe PMC";   PMID:24983832 "Europe PMC";   PMID:25019386 "Europe PMC";   PMID:25035320 "Europe PMC";   PMID:25081007 "Europe PMC";   Pesticides:oxytetracycline "Alan Wood's Pesticides";   Reaxys:2714587 "Reaxys";   VSDB:503;   Wikipedia:Oxytetracycline
 cyclic_relationship: is_tautomer_of CHEBI:133011

show annotations for term's descendants       view all columns           Sort by:
oxytetracycline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Dio1 iodothyronine deiodinase 1 JBrowse link 5 126,894,837 126,911,532 RGD:6480464
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        antimicrobial agent 17158
          oxytetracycline 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    main group molecular entity 19555
                      s-block molecular entity 19336
                        hydrogen molecular entity 19325
                          hydrides 18249
                            organic hydride 17537
                              organic fundamental parent 17537
                                hydrocarbon 16941
                                  cyclic hydrocarbon 15103
                                    arene 15090
                                      polycyclic arene 14522
                                        ortho-fused polycyclic arene 9539
                                          acene 7484
                                            tetracene 7480
                                              tetracyclines 490
                                                oxytetracycline 10
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.